CytokineticsCYTK

13F holders, Q4 2025 (December 31)
431holders +51
82new positions
46sold out
6famous investors
$63.54avg. 13F price*

At the end of Q4 2025, 431 institutions reported holding Cytokinetics Inc. (CYTK) in their 13F filings, up 51 from Q3 2025. 82 opened new positions and 46 sold out. The largest holders were T. Rowe Price Investment Management, Inc. ($1.1B), BlackRock, Inc. ($1.0B) and FMR LLC ($813.8M). 6 famous investors held it, including Ken Griffin (0.1% of Citadel Advisors's portfolio), Ken Fisher (0.0% of Fisher Asset Management's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).

Company
Cytokinetics Inc.
CUSIP
23282W605
Latest filing quarter
Q2 2026

History

Number of 13F holders

0100200300400500 Q1 2024: 389Q1 2024Q2 2024: 344Q2 2024Q3 2024: 348Q3 2024Q4 2024: 346Q4 2024Q1 2025: 355Q1 2025Q2 2025: 311Q2 2025Q3 2025: 380Q3 2025Q4 2025: 431Q4 2025Q1 2026: 441Q1 2026Q2 2026: 481Q2 2026

Total Exit/New Position Q3 2025 → Q4 2025

InstitutionsTotal Value
New Positions82$163.3M
Exits46$170.2M

All 13F filers, Q3 2025 → Q4 2025: 9,694,160 shares bought and 13,379,478 shares sold, net −3,685,318 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 431 holders

T. Rowe Price Investment Management, Inc. 0.71% Reduce -7.2% 17,716,372 $1.1B
BlackRock, Inc. 0.02% Add +5.6% 16,395,123 $1.0B
FMR LLC 0.04% Reduce -2.2% 12,807,752 $813.8M
Vanguard Group Inc. 0.01% Add +1.6% 12,048,131 $765.5M
Wellington Management Group LLP 0.09% Add +7.1% 7,937,063 $504.3M
State Street Corp. 0.01% Add +3.7% 5,825,295 $370.1M
Deep Track Capital, LP 4.84% Reduce -22.4% 3,336,998 $212.0M
Geode Capital Management, LLC 0.01% Add +0.5% 3,056,017 $194.2M
Bank of America Corp. 0.01% Reduce -3.9% 2,941,152 $186.9M
RTW Investments, LP 1.73% No change 2,721,158 $172.9M
Polar Capital Holdings Plc 0.70% Reduce -12.9% 2,422,612 $153.9M
Goldman Sachs Group Inc. 0.02% Add +45.1% 2,371,679 $150.7M
T. Rowe Price Associates Inc. 0.01% Reduce -18.4% 1,930,119 $122.6M
Woodline Partners LP 0.41% Add +0.0% 1,648,428 $104.7M
JPMorgan Chase & Co. 0.01% Reduce -8.4% 1,412,797 $89.8M
Integral Health Asset Management, LLC 4.51% No change 1,400,000 $89.0M
Charles Schwab Investment Management Inc. 0.01% Add +0.7% 1,383,437 $87.9M
Northern Trust Corp. 0.01% Reduce -1.9% 1,380,787 $87.7M
Morgan Stanley 0.00% Reduce -16.8% 1,265,301 $80.4M
Capital International Investors 0.01% No change 1,178,780 $74.9M
Citadel Advisors 0.05% Reduce -16.1% 1,162,937 $73.9M
UBS Group AG 0.01% Reduce -37.3% 1,131,456 $71.9M
Armistice Capital, LLC 1.55% Reduce -17.1% 992,766 $63.1M
Royalty Pharma Sub-Manager, LLC 36.36% — 980,392 $62.3M
Principal Financial Group Inc. 0.03% Reduce -16.8% 976,892 $62.1M
Frazier Life Sciences Management, L.P. 1.60% Add +5.0% 934,642 $59.4M
Bank of New York Mellon Corp 0.01% Reduce -1.7% 854,309 $54.3M
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.06% Add +5.5% 827,863 $52.6M
Fisher Asset Management 0.02% Add +8.1% 822,885 $52.3M
Norges Bank 0.01% — 807,070 $51.3M
Affinity Asset Advisors, LLC 3.77% Add +128.6% 800,000 $50.8M
Pictet Asset Management Holding SA 0.05% Reduce -33.9% 757,563 $48.0M
Susquehanna International Group, LLP 0.07% Reduce -26.0% 753,617 $47.9M
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. 4.22% Reduce -37.3% 747,983 $47.5M
Brown Advisory Inc. 0.06% Reduce -19.9% 731,154 $46.5M
Melqart Asset Management (UK) Ltd 3.96% Reduce -20.5% 622,898 $39.6M
BNP Paribas Financial Markets 0.02% Add +134.3% 579,862 $36.8M
Ameriprise Financial Inc. 0.01% Reduce -3.3% 545,805 $34.7M
TD Asset Management Inc 0.03% Reduce -19.0% 544,010 $34.6M
ADAR1 Capital Management, LLC 2.57% Add +4.1% 540,166 $34.3M
Qube Research & Technologies Ltd 0.05% Add +5844.6% 537,277 $34.1M
Federated Hermes, Inc. 0.05% Add +1775.1% 483,668 $30.7M
Aberdeen Group plc 0.05% Reduce -47.9% 483,061 $30.7M
Eventide Asset Management, LLC 0.48% Add +181.9% 479,611 $30.5M
GW&K Investment Management, LLC 0.26% Add +161.4% 472,363 $30.0M
Foresite Capital Management IV, LLC 12.68% No change 458,295 $29.1M
American Century Companies Inc. 0.01% Add +3.4% 443,910 $28.2M
Alliancebernstein L.P. 0.01% Add +75.4% 412,966 $26.2M
Franklin Resources Inc. 0.01% Add +0.1% 409,990 $26.1M
Group One Trading LLC 0.77% Add +116.7% 407,253 $25.9M
Sarissa Capital Management LP 11.30% Reduce -32.6% 396,357 $25.2M
Gilder Gagnon Howe & Co. LLC 0.26% Reduce -0.8% 385,820 $24.5M
DAFNA Capital Management LLC 5.55% Reduce -6.1% 370,997 $23.6M
Nuveen, LLC 0.01% Reduce -0.4% 369,279 $23.5M
E. Ohman J:or Asset Management AB 0.54% Reduce -10.8% 362,962 $23.1M
Rhumbline Advisers 0.02% Reduce -7.5% 356,995 $22.7M
Barclays PLC 0.01% Reduce -13.7% 343,458 $21.8M
ExodusPoint Capital Management, LP 0.24% New 343,144 $21.8M
GSK plc 2.71% — 340,434 $21.6M
Marshall Wace, LLP 0.02% Add +88.3% 337,031 $21.4M
Massachusetts Financial Services Co. 0.01% Reduce -34.1% 327,202 $20.8M
First Turn Management, LLC 2.36% Add +27.8% 325,668 $20.7M
Logos Global Management LP 1.27% New 300,000 $19.1M
Jane Street Group, LLC 0.02% New 284,125 $18.1M
Susquehanna Portfolio Strategies, LLC 0.27% No change 278,429 $17.7M
Two Sigma Investments, LP 0.03% New 274,017 $17.4M
Catalio Capital Management, LP 2.90% Reduce -42.8% 258,381 $16.4M
Janus Henderson Group PLC 0.01% Add +416.9% 256,212 $16.3M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% Reduce -1.4% 235,049 $14.9M
AQR Capital Management 0.01% Reduce -53.8% 236,925 $14.8M
Millennium Management 0.01% Reduce -34.2% 225,456 $14.3M
Swiss National Bank 0.01% Add +2.0% 224,200 $14.2M
Handelsbanken Fonder AB 0.04% Reduce -12.2% 205,800 $13.1M
Invesco Ltd. 0.00% Add +30.3% 204,878 $13.0M
Mirador Capital Partners LP 1.73% Add +0.6% 198,558 $12.6M
Rosalind Advisors, Inc. 4.52% Reduce -51.2% 195,045 $12.4M
Pinnacle Associates Ltd. 0.16% Reduce -5.2% 190,999 $12.1M
Segall Bryant & Hamill, LLC 0.16% Add +4.7% 189,513 $12.0M
California Public Employees Retirement System 0.01% Add +25.9% 189,401 $12.0M
Manufacturers Life Insurance Company, The 0.01% Reduce -0.6% 190,807 $12.0M
Deutsche Bank AG 0.00% Add +6.2% 175,804 $11.2M
Hudson Bay Capital Management LP 0.07% Reduce -3.7% 175,350 $11.1M
Two Sigma Advisers, LP 0.02% New 174,700 $11.1M
Ikarian Capital, LLC 1.42% Reduce -22.5% 172,672 $11.0M
Renaissance Technologies 0.02% Reduce -40.7% 172,067 $10.9M
Legal & General Group Plc 0.00% Reduce -6.2% 168,586 $10.7M
Checkpoint Capital L.P. 3.36% Add +343.8% 166,823 $10.6M
Wells Fargo & Company 0.00% Add +65.8% 161,556 $10.3M
Stempoint Capital LP 1.60% New 146,978 $9.3M
Retirement Systems of Alabama 0.03% Add +1.4% 146,668 $9.3M
Candriam S.C.A. 0.05% New 146,631 $9.3M
Royce & Associates LP 0.09% Add +44.3% 144,426 $9.2M
Russell Investments Group, Ltd. 0.01% Add +14.8% 137,690 $8.7M
Hood River Capital Management LLC 0.10% New 137,597 $8.7M
First Trust Advisors LP 0.01% New 127,524 $8.1M
Exome Asset Management LLC 3.92% Reduce -12.4% 124,749 $7.9M
Readystate Asset Management LP 0.60% Reduce -13.9% 122,711 $7.8M
MetLife Investment Management, LLC 0.04% Reduce -4.5% 121,910 $7.7M
D. E. Shaw & Co. 0.01% Add +776.4% 119,221 $7.6M
HighVista Strategies LLC 1.87% Reduce -13.8% 114,564 $7.3M

"% of holder's portfolio" is CYTK's weight in each manager's 13F, not the share of Cytokinetics Inc. the manager owns.

Show all 431 holders