CytokineticsCYTK
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 431 institutions reported holding Cytokinetics Inc. (CYTK) in their 13F filings, up 51 from Q3 2025. 82 opened new positions and 46 sold out. The largest holders were T. Rowe Price Investment Management, Inc. ($1.1B), BlackRock, Inc. ($1.0B) and FMR LLC ($813.8M). 6 famous investors held it, including Ken Griffin (0.1% of Citadel Advisors's portfolio), Ken Fisher (0.0% of Fisher Asset Management's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).
- Company
- Cytokinetics Inc.
- CUSIP
- 23282W605
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 82 | $163.3M |
| Exits | 46 | $170.2M |
All 13F filers, Q3 2025 → Q4 2025: 9,694,160 shares bought and 13,379,478 shares sold, net −3,685,318 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 431 holders
| T. Rowe Price Investment Management, Inc. | 0.71% | Reduce -7.2% | 17,716,372 | $1.1B |
| BlackRock, Inc. | 0.02% | Add +5.6% | 16,395,123 | $1.0B |
| FMR LLC | 0.04% | Reduce -2.2% | 12,807,752 | $813.8M |
| Vanguard Group Inc. | 0.01% | Add +1.6% | 12,048,131 | $765.5M |
| Wellington Management Group LLP | 0.09% | Add +7.1% | 7,937,063 | $504.3M |
| State Street Corp. | 0.01% | Add +3.7% | 5,825,295 | $370.1M |
| Deep Track Capital, LP | 4.84% | Reduce -22.4% | 3,336,998 | $212.0M |
| Geode Capital Management, LLC | 0.01% | Add +0.5% | 3,056,017 | $194.2M |
| Bank of America Corp. | 0.01% | Reduce -3.9% | 2,941,152 | $186.9M |
| RTW Investments, LP | 1.73% | No change | 2,721,158 | $172.9M |
| Polar Capital Holdings Plc | 0.70% | Reduce -12.9% | 2,422,612 | $153.9M |
| Goldman Sachs Group Inc. | 0.02% | Add +45.1% | 2,371,679 | $150.7M |
| T. Rowe Price Associates Inc. | 0.01% | Reduce -18.4% | 1,930,119 | $122.6M |
| Woodline Partners LP | 0.41% | Add +0.0% | 1,648,428 | $104.7M |
| JPMorgan Chase & Co. | 0.01% | Reduce -8.4% | 1,412,797 | $89.8M |
| Integral Health Asset Management, LLC | 4.51% | No change | 1,400,000 | $89.0M |
| Charles Schwab Investment Management Inc. | 0.01% | Add +0.7% | 1,383,437 | $87.9M |
| Northern Trust Corp. | 0.01% | Reduce -1.9% | 1,380,787 | $87.7M |
| Morgan Stanley | 0.00% | Reduce -16.8% | 1,265,301 | $80.4M |
| Capital International Investors | 0.01% | No change | 1,178,780 | $74.9M |
| Citadel Advisors | 0.05% | Reduce -16.1% | 1,162,937 | $73.9M |
| UBS Group AG | 0.01% | Reduce -37.3% | 1,131,456 | $71.9M |
| Armistice Capital, LLC | 1.55% | Reduce -17.1% | 992,766 | $63.1M |
| Royalty Pharma Sub-Manager, LLC | 36.36% | — | 980,392 | $62.3M |
| Principal Financial Group Inc. | 0.03% | Reduce -16.8% | 976,892 | $62.1M |
| Frazier Life Sciences Management, L.P. | 1.60% | Add +5.0% | 934,642 | $59.4M |
| Bank of New York Mellon Corp | 0.01% | Reduce -1.7% | 854,309 | $54.3M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.06% | Add +5.5% | 827,863 | $52.6M |
| Fisher Asset Management | 0.02% | Add +8.1% | 822,885 | $52.3M |
| Norges Bank | 0.01% | — | 807,070 | $51.3M |
| Affinity Asset Advisors, LLC | 3.77% | Add +128.6% | 800,000 | $50.8M |
| Pictet Asset Management Holding SA | 0.05% | Reduce -33.9% | 757,563 | $48.0M |
| Susquehanna International Group, LLP | 0.07% | Reduce -26.0% | 753,617 | $47.9M |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | 4.22% | Reduce -37.3% | 747,983 | $47.5M |
| Brown Advisory Inc. | 0.06% | Reduce -19.9% | 731,154 | $46.5M |
| Melqart Asset Management (UK) Ltd | 3.96% | Reduce -20.5% | 622,898 | $39.6M |
| BNP Paribas Financial Markets | 0.02% | Add +134.3% | 579,862 | $36.8M |
| Ameriprise Financial Inc. | 0.01% | Reduce -3.3% | 545,805 | $34.7M |
| TD Asset Management Inc | 0.03% | Reduce -19.0% | 544,010 | $34.6M |
| ADAR1 Capital Management, LLC | 2.57% | Add +4.1% | 540,166 | $34.3M |
| Qube Research & Technologies Ltd | 0.05% | Add +5844.6% | 537,277 | $34.1M |
| Federated Hermes, Inc. | 0.05% | Add +1775.1% | 483,668 | $30.7M |
| Aberdeen Group plc | 0.05% | Reduce -47.9% | 483,061 | $30.7M |
| Eventide Asset Management, LLC | 0.48% | Add +181.9% | 479,611 | $30.5M |
| GW&K Investment Management, LLC | 0.26% | Add +161.4% | 472,363 | $30.0M |
| Foresite Capital Management IV, LLC | 12.68% | No change | 458,295 | $29.1M |
| American Century Companies Inc. | 0.01% | Add +3.4% | 443,910 | $28.2M |
| Alliancebernstein L.P. | 0.01% | Add +75.4% | 412,966 | $26.2M |
| Franklin Resources Inc. | 0.01% | Add +0.1% | 409,990 | $26.1M |
| Group One Trading LLC | 0.77% | Add +116.7% | 407,253 | $25.9M |
| Sarissa Capital Management LP | 11.30% | Reduce -32.6% | 396,357 | $25.2M |
| Gilder Gagnon Howe & Co. LLC | 0.26% | Reduce -0.8% | 385,820 | $24.5M |
| DAFNA Capital Management LLC | 5.55% | Reduce -6.1% | 370,997 | $23.6M |
| Nuveen, LLC | 0.01% | Reduce -0.4% | 369,279 | $23.5M |
| E. Ohman J:or Asset Management AB | 0.54% | Reduce -10.8% | 362,962 | $23.1M |
| Rhumbline Advisers | 0.02% | Reduce -7.5% | 356,995 | $22.7M |
| Barclays PLC | 0.01% | Reduce -13.7% | 343,458 | $21.8M |
| ExodusPoint Capital Management, LP | 0.24% | New | 343,144 | $21.8M |
| GSK plc | 2.71% | — | 340,434 | $21.6M |
| Marshall Wace, LLP | 0.02% | Add +88.3% | 337,031 | $21.4M |
| Massachusetts Financial Services Co. | 0.01% | Reduce -34.1% | 327,202 | $20.8M |
| First Turn Management, LLC | 2.36% | Add +27.8% | 325,668 | $20.7M |
| Logos Global Management LP | 1.27% | New | 300,000 | $19.1M |
| Jane Street Group, LLC | 0.02% | New | 284,125 | $18.1M |
| Susquehanna Portfolio Strategies, LLC | 0.27% | No change | 278,429 | $17.7M |
| Two Sigma Investments, LP | 0.03% | New | 274,017 | $17.4M |
| Catalio Capital Management, LP | 2.90% | Reduce -42.8% | 258,381 | $16.4M |
| Janus Henderson Group PLC | 0.01% | Add +416.9% | 256,212 | $16.3M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -1.4% | 235,049 | $14.9M |
| AQR Capital Management | 0.01% | Reduce -53.8% | 236,925 | $14.8M |
| Millennium Management | 0.01% | Reduce -34.2% | 225,456 | $14.3M |
| Swiss National Bank | 0.01% | Add +2.0% | 224,200 | $14.2M |
| Handelsbanken Fonder AB | 0.04% | Reduce -12.2% | 205,800 | $13.1M |
| Invesco Ltd. | 0.00% | Add +30.3% | 204,878 | $13.0M |
| Mirador Capital Partners LP | 1.73% | Add +0.6% | 198,558 | $12.6M |
| Rosalind Advisors, Inc. | 4.52% | Reduce -51.2% | 195,045 | $12.4M |
| Pinnacle Associates Ltd. | 0.16% | Reduce -5.2% | 190,999 | $12.1M |
| Segall Bryant & Hamill, LLC | 0.16% | Add +4.7% | 189,513 | $12.0M |
| California Public Employees Retirement System | 0.01% | Add +25.9% | 189,401 | $12.0M |
| Manufacturers Life Insurance Company, The | 0.01% | Reduce -0.6% | 190,807 | $12.0M |
| Deutsche Bank AG | 0.00% | Add +6.2% | 175,804 | $11.2M |
| Hudson Bay Capital Management LP | 0.07% | Reduce -3.7% | 175,350 | $11.1M |
| Two Sigma Advisers, LP | 0.02% | New | 174,700 | $11.1M |
| Ikarian Capital, LLC | 1.42% | Reduce -22.5% | 172,672 | $11.0M |
| Renaissance Technologies | 0.02% | Reduce -40.7% | 172,067 | $10.9M |
| Legal & General Group Plc | 0.00% | Reduce -6.2% | 168,586 | $10.7M |
| Checkpoint Capital L.P. | 3.36% | Add +343.8% | 166,823 | $10.6M |
| Wells Fargo & Company | 0.00% | Add +65.8% | 161,556 | $10.3M |
| Stempoint Capital LP | 1.60% | New | 146,978 | $9.3M |
| Retirement Systems of Alabama | 0.03% | Add +1.4% | 146,668 | $9.3M |
| Candriam S.C.A. | 0.05% | New | 146,631 | $9.3M |
| Royce & Associates LP | 0.09% | Add +44.3% | 144,426 | $9.2M |
| Russell Investments Group, Ltd. | 0.01% | Add +14.8% | 137,690 | $8.7M |
| Hood River Capital Management LLC | 0.10% | New | 137,597 | $8.7M |
| First Trust Advisors LP | 0.01% | New | 127,524 | $8.1M |
| Exome Asset Management LLC | 3.92% | Reduce -12.4% | 124,749 | $7.9M |
| Readystate Asset Management LP | 0.60% | Reduce -13.9% | 122,711 | $7.8M |
| MetLife Investment Management, LLC | 0.04% | Reduce -4.5% | 121,910 | $7.7M |
| D. E. Shaw & Co. | 0.01% | Add +776.4% | 119,221 | $7.6M |
| HighVista Strategies LLC | 1.87% | Reduce -13.8% | 114,564 | $7.3M |
"% of holder's portfolio" is CYTK's weight in each manager's 13F, not the share of Cytokinetics Inc. the manager owns.