Ensysce BiosciencesENSC

13F holders, Q3 2025 (September 30)
17holders +6
8new positions
2sold out
2famous investors
$2.37avg. 13F price*

At the end of Q3 2025, 17 institutions reported holding Ensysce Biosciences Inc. (ENSC) in their 13F filings, up 6 from Q2 2025. 8 opened new positions and 2 sold out. The largest holders were Perceptive Advisors LLC ($205K), Adage Capital Partners Gp, L.L.C. ($177K) and DRW Securities, LLC ($164K). 2 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).

Company
Ensysce Biosciences Inc.
CUSIP
293602504
Latest filing quarter
Q2 2026

History

Number of 13F holders

05101520 Q4 2024: 8Q4 2024Q1 2025: 9Q1 2025Q2 2025: 11Q2 2025Q3 2025: 17Q3 2025Q4 2025: 17Q4 2025Q1 2026: 15Q1 2026Q2 2026: 18Q2 2026

Total Exit/New Position Q2 2025 → Q3 2025

InstitutionsTotal Value
New Positions8$407K
Exits2$1K

All 13F filers, Q2 2025 → Q3 2025: 174,957 shares bought and 2,411 shares sold, net +172,546 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 17 holders

Perceptive Advisors LLC 0.01% No change 86,666 $205K
Adage Capital Partners Gp, L.L.C. 0.00% No change 74,711 $177K
DRW Securities, LLC 0.01% New 69,145 $164K
Vanguard Group Inc. 0.00% New 36,708 $87K
Renaissance Technologies 0.00% New 15,574 $37K
Citadel Advisors 0.00% New 14,518 $34K
Virtu Financial LLC 0.00% New 14,222 $34K
Geode Capital Management, LLC 0.00% Add +28.2% 13,030 $31K
XTX Topco Ltd 0.00% New 10,957 $26K
Tru Independence Asset Management 2, LLC 0.02% New 10,500 $25K
FNY Investment Advisers, LLC 0.00% No change 3,000 $7K
Tower Research Capital LLC (TRC) 0.00% Reduce -1.5% 1,348 $3K
UBS Group AG 0.00% Add +126.0% 800 $2K
SBI Securities Co., Ltd. 0.00% Reduce -82.1% 418 $991
BlackRock, Inc. 0.00% No change 65 $154
Bank of America Corp. 0.00% Add +26.3% 24 $57
Assetmark, Inc. 0.00% New 13 $31

"% of holder's portfolio" is ENSC's weight in each manager's 13F, not the share of Ensysce Biosciences Inc. the manager owns.