Ensysce BiosciencesENSC

13F holders, Q4 2025 (December 31)
17holders
4new positions
5sold out
$0.92avg. 13F price*

At the end of Q4 2025, 17 institutions reported holding Ensysce Biosciences Inc. (ENSC) in their 13F filings, unchanged from Q3 2025. 4 opened new positions and 5 sold out. The largest holders were Adage Capital Partners Gp, L.L.C. ($138K), DRW Securities, LLC ($91K) and Perceptive Advisors LLC ($80K).

Company
Ensysce Biosciences Inc.
CUSIP
293602504
Latest filing quarter
Q2 2026

History

Number of 13F holders

05101520 Q4 2024: 8Q4 2024Q1 2025: 9Q1 2025Q2 2025: 11Q2 2025Q3 2025: 17Q3 2025Q4 2025: 17Q4 2025Q1 2026: 15Q1 2026Q2 2026: 18Q2 2026

Total Exit/New Position Q3 2025 → Q4 2025

InstitutionsTotal Value
New Positions4$58K
Exits5$131K

All 13F filers, Q3 2025 → Q4 2025: 182,905 shares bought and 55,984 shares sold, net +126,921 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 17 holders

Adage Capital Partners Gp, L.L.C. 0.00% Add +100.4% 149,711 $138K
DRW Securities, LLC 0.01% Add +42.4% 98,481 $91K
Perceptive Advisors LLC 0.00% No change 86,666 $80K
Vanguard Group Inc. 0.00% No change 36,708 $34K
Financial Plan, Inc. 0.00% — 24,000 $22K
HRT Financial LP 0.00% New 24,491 $22K
Geode Capital Management, LLC 0.00% Add +69.5% 22,090 $20K
Two Sigma Securities, LLC 0.00% New 21,605 $20K
Williams & Novak, LLC 0.01% New 17,850 $16K
Tru Independence Asset Management 2, LLC 0.01% Add +14.3% 12,000 $11K
Tower Research Capital LLC (TRC) 0.00% Add +294.6% 5,319 $5K
FNY Investment Advisers, LLC 0.00% No change 3,000 $2K
SBI Securities Co., Ltd. 0.00% Add +0.7% 421 $387
UBS Group AG 0.00% Reduce -87.5% 100 $92
Bank of America Corp. 0.00% Add +200.0% 72 $66
BlackRock, Inc. 0.00% No change 65 $60
Jones Financial Companies LLLP 0.00% New 41 $38

"% of holder's portfolio" is ENSC's weight in each manager's 13F, not the share of Ensysce Biosciences Inc. the manager owns.