Eton PharmaceuticalsETON
13F holders, Q4 2024 (December 31)At the end of Q4 2024, 71 institutions reported holding Eton Pharmaceuticals Inc. (ETON) in their 13F filings, up 23 from Q3 2024. 24 opened new positions and 3 sold out. The largest holders were Opaleye Management Inc. ($38.0M), EcoR1 Capital, LLC ($24.4M) and Nantahala Capital Management, LLC ($14.9M). 2 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Eton Pharmaceuticals Inc.
- CUSIP
- 29772L108
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2024 → Q4 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 24 | $16.5M |
| Exits | 3 | $83K |
All 13F filers, Q3 2024 → Q4 2024: 3,788,781 shares bought and 618,038 shares sold, net +3,170,743 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 71 holders
| Opaleye Management Inc. | 6.78% | Add +2.6% | 2,852,070 | $38.0M |
| EcoR1 Capital, LLC | 0.97% | Add +223.2% | 1,829,603 | $24.4M |
| Nantahala Capital Management, LLC | 1.04% | Add +12.0% | 1,118,483 | $14.9M |
| Vanguard Group Inc. | 0.00% | Add +3.5% | 1,063,707 | $14.2M |
| Westside Investment Management, Inc. | 1.61% | Reduce -7.0% | 575,222 | $7.7M |
| National Philanthropic Trust | 0.09% | No change | 492,112 | $6.6M |
| Mink Brook Asset Management LLC | 5.81% | — | 455,805 | $6.1M |
| Cannell Capital LLC | 1.05% | New | 381,323 | $5.1M |
| BlackRock, Inc. | 0.00% | Add +11.5% | 317,625 | $4.2M |
| Parkman Healthcare Partners LLC | 0.49% | Add +6.4% | 276,890 | $3.7M |
| Geode Capital Management, LLC | 0.00% | Reduce -1.5% | 268,646 | $3.6M |
| Acadian Asset Management LLC | 0.01% | Add +134.5% | 248,505 | $3.3M |
| Aristides Capital LLC | 1.01% | Add +20.8% | 241,587 | $3.2M |
| Bridgeway Capital Management, LLC | 0.07% | Reduce -5.7% | 238,962 | $3.2M |
| Wasatch Advisors LP | 0.02% | Reduce -3.0% | 231,328 | $3.1M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.01% | Add +230.5% | 214,878 | $2.9M |
| Paradigm Capital Management Inc. | 0.12% | Reduce -33.3% | 200,000 | $2.7M |
| Renaissance Technologies | 0.00% | Add +131.5% | 193,100 | $2.6M |
| Susquehanna International Group, LLP | 0.00% | Add +61.1% | 192,326 | $2.6M |
| Acuitas Investments, LLC | 2.03% | Reduce -68.0% | 185,824 | $2.5M |
| Millennium Management | 0.00% | New | 138,887 | $1.8M |
| UBS Group AG | 0.00% | Add +611.7% | 135,352 | $1.8M |
| Goldman Sachs Group Inc. | 0.00% | New | 129,879 | $1.7M |
| Thompson Siegel & Walmsley LLC | 0.03% | Add +11.3% | 128,039 | $1.7M |
| Two Sigma Investments, LP | 0.00% | New | 112,458 | $1.5M |
| State Street Corp. | 0.00% | Add +29.4% | 105,336 | $1.4M |
| Informed Momentum Co LLC | 0.18% | Reduce -25.9% | 95,019 | $1.3M |
| Qube Research & Technologies Ltd | 0.00% | Add +191.2% | 94,181 | $1.3M |
| Schonfeld Strategic Advisors LLC | 0.01% | Add +421.3% | 89,664 | $1.2M |
| Northern Trust Corp. | 0.00% | Add +35.6% | 86,957 | $1.2M |
| Bank of New York Mellon Corp | 0.00% | Reduce -0.3% | 74,246 | $989K |
| 683 Capital Management, LLC | 0.10% | New | 69,000 | $919K |
| Jane Street Group, LLC | 0.00% | Add +328.6% | 64,323 | $857K |
| Anchor Capital Advisors LLC | 0.02% | New | 60,432 | $805K |
| Barclays PLC | 0.00% | New | 54,886 | $731K |
| JPMorgan Chase & Co. | 0.00% | Add +7086.9% | 51,961 | $692K |
| Two Sigma Advisers, LP | 0.00% | New | 49,700 | $662K |
| Cubist Systematic Strategies, LLC | 0.01% | Add +422.9% | 43,239 | $576K |
| OMERS ADMINISTRATION Corp | 0.00% | New | 37,900 | $505K |
| Simplex Trading, LLC | 0.01% | New | 36,376 | $484K |
| Marshall Wace, LLP | 0.00% | Add +75.3% | 36,182 | $482K |
| Blair William & Co. | 0.00% | Add +1.2% | 34,900 | $465K |
| Baader Bank Aktiengesellschaft | 0.03% | New | 28,000 | $373K |
| Jump Financial, LLC | 0.01% | New | 24,710 | $329K |
| Essex Investment Management Co. LLC | 0.06% | Reduce -10.3% | 24,442 | $326K |
| Prelude Capital Management, LLC | 0.03% | New | 24,242 | $323K |
| Citigroup Inc. | 0.00% | Reduce -17.1% | 21,977 | $293K |
| Envestnet Asset Management Inc. | 0.00% | New | 17,740 | $236K |
| Hillsdale Investment Management Inc. | 0.01% | New | 17,003 | $226K |
| CHICAGO TRUST Co NA | 0.04% | No change | 16,700 | $222K |
| XTX Topco Ltd | 0.02% | Add +29.6% | 14,655 | $195K |
| Charles Schwab Investment Management Inc. | 0.00% | No change | 13,239 | $176K |
| Morgan Stanley | 0.00% | Add +2695.1% | 13,193 | $176K |
| Engineers Gate Manager LP | 0.00% | New | 12,589 | $168K |
| Atom Investors LP | 0.02% | New | 12,068 | $161K |
| Balyasny Asset Management L.P. | 0.00% | New | 11,850 | $158K |
| Quantum Private Wealth, LLC | 0.05% | No change | 11,500 | $153K |
| Bank of America Corp. | 0.00% | Add +5422.4% | 11,100 | $148K |
| Raymond James Financial Inc. | 0.00% | — | 11,043 | $147K |
| Point72 Asia (Singapore) Pte. Ltd. | 0.04% | Add +18.3% | 10,561 | $141K |
| Jefferies Financial Group Inc. | 0.00% | New | 10,000 | $133K |
| Tower Research Capital LLC (TRC) | 0.00% | New | 6,433 | $86K |
| Point72 (DIFC) Ltd | 0.00% | New | 1,441 | $19K |
| Federated Hermes, Inc. | 0.00% | New | 1,392 | $19K |
| Truvestments Capital LLC | 0.00% | No change | 1,183 | $16K |
| Wells Fargo & Company | 0.00% | New | 1,000 | $13K |
| Lazard Asset Management LLC | 0.00% | New | 1,031 | $13K |
| Royal Bank of Canada | 0.00% | Add +173.4% | 752 | $10K |
| BNP Paribas Financial Markets | 0.00% | No change | 350 | $5K |
| Osaic Holdings, Inc. | 0.00% | Reduce -13.3% | 260 | $3K |
| SBI Securities Co., Ltd. | 0.00% | — | 141 | $2K |
"% of holder's portfolio" is ETON's weight in each manager's 13F, not the share of Eton Pharmaceuticals Inc. the manager owns.