Eton PharmaceuticalsETON
13F holders, Q3 2025 (September 30)103holders +16
27new positions
11sold out
2famous investors
$21.88avg. 13F price*
At the end of Q3 2025, 103 institutions reported holding Eton Pharmaceuticals Inc. (ETON) in their 13F filings, up 16 from Q2 2025. 27 opened new positions and 11 sold out. The largest holders were Opaleye Management Inc. ($62.1M), EcoR1 Capital, LLC ($44.1M) and BlackRock, Inc. ($37.0M). 2 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Eton Pharmaceuticals Inc.
- CUSIP
- 29772L108
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 27 | $20.8M |
| Exits | 11 | $4.4M |
All 13F filers, Q2 2025 → Q3 2025: 2,457,846 shares bought and 1,340,073 shares sold, net +1,117,773 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 103 holders
| Opaleye Management Inc. | 8.84% | No change | 2,860,000 | $62.1M |
| EcoR1 Capital, LLC | 2.12% | No change | 2,030,544 | $44.1M |
| BlackRock, Inc. | 0.00% | Add +11.3% | 1,704,361 | $37.0M |
| Vanguard Group Inc. | 0.00% | Add +2.4% | 1,344,115 | $29.2M |
| Nantahala Capital Management, LLC | 1.58% | No change | 1,175,951 | $25.6M |
| Morgan Stanley | 0.00% | Add +15.0% | 586,046 | $12.7M |
| Geode Capital Management, LLC | 0.00% | Reduce -3.2% | 574,030 | $12.5M |
| National Philanthropic Trust | 0.12% | No change | 492,112 | $10.7M |
| Royal Bank of Canada | 0.00% | Add +9360.9% | 479,193 | $10.4M |
| Westside Investment Management, Inc. | 1.64% | Reduce -0.1% | 472,540 | $10.3M |
| Cannell Capital LLC | 2.60% | Add +17.3% | 455,405 | $9.9M |
| State Street Corp. | 0.00% | Add +35.7% | 438,445 | $9.5M |
| Thompson Siegel & Walmsley LLC | 0.15% | Add +9.8% | 418,566 | $9.1M |
| JPMorgan Chase & Co. | 0.00% | Add +44.9% | 351,417 | $7.6M |
| Renaissance Technologies | 0.01% | Reduce -20.0% | 324,621 | $7.1M |
| Divisadero Street Capital Management, LP | 0.30% | Reduce -40.1% | 298,000 | $6.5M |
| Two Sigma Investments, LP | 0.01% | Add +33.5% | 286,421 | $6.2M |
| Northern Trust Corp. | 0.00% | Reduce -6.5% | 245,051 | $5.3M |
| BNP Paribas Financial Markets | 0.00% | Add +162.0% | 229,790 | $5.0M |
| UBS Group AG | 0.00% | Add +3.7% | 220,361 | $4.8M |
| Soleus Capital Management, L.P. | 0.23% | Reduce -29.8% | 200,000 | $4.3M |
| Oberweis Asset Management Inc./ | 0.16% | New | 192,360 | $4.2M |
| Goldman Sachs Group Inc. | 0.00% | Add +73.9% | 190,164 | $4.1M |
| Lumbard & Kellner, LLC | 1.41% | New | 176,300 | $3.8M |
| Two Sigma Advisers, LP | 0.01% | Add +67.4% | 168,900 | $3.7M |
| Aristides Capital LLC | 1.08% | No change | 167,587 | $3.6M |
| Summit Wealth Group LLC / Co. | 0.35% | New | 25,999 | $3.3M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.01% | Reduce -35.2% | 143,811 | $3.1M |
| Bank of New York Mellon Corp | 0.00% | Add +1.4% | 129,182 | $2.8M |
| Apis Capital Advisors, LLC | 0.56% | Add +10.9% | 117,600 | $2.6M |
| Bridgeway Capital Management, LLC | 0.05% | Reduce -19.4% | 109,020 | $2.4M |
| Diametric Capital, LP | 0.80% | Add +17.0% | 99,309 | $2.2M |
| Jefferies Financial Group Inc. | 0.02% | New | 88,440 | $1.9M |
| Wellington Management Group LLP | 0.00% | Add +202.0% | 88,219 | $1.9M |
| Raymond James Financial Inc. | 0.00% | Reduce -3.7% | 87,082 | $1.9M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -0.7% | 77,274 | $1.7M |
| Bank of America Corp. | 0.00% | Add +102.2% | 74,657 | $1.6M |
| Jane Street Group, LLC | 0.00% | New | 70,944 | $1.5M |
| Squarepoint Ops LLC | 0.00% | Reduce -36.4% | 59,645 | $1.3M |
| Nuveen, LLC | 0.00% | No change | 58,917 | $1.3M |
| Russell Investments Group, Ltd. | 0.00% | Add +202.9% | 54,865 | $1.2M |
| Informed Momentum Co LLC | 0.13% | New | 52,897 | $1.1M |
| Prelude Capital Management, LLC | 0.07% | Reduce -4.0% | 41,873 | $910K |
| Barclays PLC | 0.00% | Reduce -19.6% | 36,806 | $800K |
| Anchor Capital Advisors LLC | 0.02% | Reduce -58.0% | 36,778 | $799K |
| Aquatic Capital Management LLC | 0.01% | Add +1.3% | 36,332 | $789K |
| Rhumbline Advisers | 0.00% | Reduce -1.3% | 36,124 | $785K |
| WINTON GROUP Ltd | 0.03% | New | 35,304 | $767K |
| Blair William & Co. | 0.00% | No change | 32,400 | $704K |
| Susquehanna International Group, LLP | 0.00% | Reduce -1.8% | 30,056 | $653K |
| Acadian Asset Management LLC | 0.00% | Reduce -93.3% | 26,410 | $573K |
| XTX Topco Ltd | 0.03% | New | 24,399 | $530K |
| Calamos Advisors LLC | 0.00% | New | 23,634 | $514K |
| Essex Investment Management Co. LLC | 0.07% | No change | 20,182 | $439K |
| Hillsdale Investment Management Inc. | 0.01% | Reduce -2.1% | 18,503 | $402K |
| Navellier & Associates Inc. | 0.04% | New | 17,494 | $380K |
| Deutsche Bank AG | 0.00% | No change | 17,399 | $378K |
| Juncture Wealth Strategies, LLC | 0.12% | New | 16,968 | $369K |
| Wells Fargo & Company | 0.00% | Add +21.5% | 16,709 | $363K |
| CHICAGO TRUST Co NA | 0.05% | No change | 16,700 | $363K |
| Bridge City Capital, LLC | 0.10% | New | 16,673 | $362K |
| Millennium Management | 0.00% | New | 15,862 | $345K |
| MetLife Investment Management, LLC | 0.00% | No change | 15,537 | $338K |
| PDT Partners, LLC | 0.02% | No change | 14,891 | $324K |
| Sheets Smith Investment Management | 0.21% | New | 14,842 | $323K |
| Gsa Capital Partners LLP | 0.03% | New | 14,785 | $321K |
| T. Rowe Price Associates Inc. | 0.00% | Add +5.3% | 13,524 | $294K |
| Invesco Ltd. | 0.00% | No change | 13,478 | $293K |
| Man Group plc | 0.00% | Reduce -46.8% | 12,649 | $275K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -14.5% | 12,007 | $261K |
| Quantbot Technologies LP | 0.01% | Reduce -54.3% | 11,532 | $251K |
| Quantum Private Wealth, LLC | 0.07% | No change | 11,500 | $250K |
| Envestnet Asset Management Inc. | 0.00% | Reduce -50.6% | 11,377 | $247K |
| Intech Investment Management LLC | 0.00% | Reduce -7.4% | 11,177 | $243K |
| Voleon Capital Management LP | 0.01% | New | 10,950 | $238K |
| PharVision Advisers, LLC | 0.13% | New | 10,535 | $229K |
| Northwestern Mutual Wealth Management Co. | 0.00% | No change | 10,000 | $217K |
| Alliancebernstein L.P. | 0.00% | New | 9,600 | $209K |
| EntryPoint Capital, LLC | 0.08% | New | 9,365 | $204K |
| New York State Common Retirement Fund | 0.00% | No change | 8,100 | $176K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +17.5% | 7,209 | $157K |
| FMR LLC | 0.00% | Add +1151.4% | 5,694 | $124K |
| State of Wyoming | 0.01% | Reduce -52.7% | 5,440 | $118K |
| AlphaQuest LLC | 0.01% | Reduce -30.2% | 4,150 | $90K |
| Legal & General Group Plc | 0.00% | No change | 2,852 | $62K |
| Ameritas Investment Partners, Inc. | 0.00% | Reduce -17.2% | 2,167 | $47K |
| Quarry LP | 0.01% | New | 1,700 | $37K |
| California State Teachers Retirement System | 0.00% | Add +0.1% | 1,601 | $35K |
| State of Alaska, Department of Revenue | 0.00% | New | 1,421 | $30K |
| Citigroup Inc. | 0.00% | Reduce -86.7% | 1,211 | $26K |
| Truvestments Capital LLC | 0.00% | No change | 1,183 | $26K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -62.0% | 971 | $21K |
| Amalgamated Bank | 0.00% | No change | 876 | $19K |
| Group One Trading LLC | 0.00% | New | 762 | $17K |
| Comerica Bank | 0.00% | New | 219 | $5K |
| Osaic Holdings, Inc. | 0.00% | No change | 200 | $4K |
| Vermillion & White Wealth Management Group, LLC | 0.00% | No change | 150 | $3K |
| SBI Securities Co., Ltd. | 0.00% | Add +25.5% | 128 | $3K |
| Sterling Capital Management LLC | 0.00% | No change | 62 | $1K |
| Advisory Services Network, LLC | 0.00% | New | 50 | $1K |
"% of holder's portfolio" is ETON's weight in each manager's 13F, not the share of Eton Pharmaceuticals Inc. the manager owns.