Eton PharmaceuticalsETON
13F holders, Q1 2025 (March 31)At the end of Q1 2025, 86 institutions reported holding Eton Pharmaceuticals Inc. (ETON) in their 13F filings, up 15 from Q4 2024. 26 opened new positions and 11 sold out. The largest holders were Opaleye Management Inc. ($37.0M), EcoR1 Capital, LLC ($25.2M) and Nantahala Capital Management, LLC ($15.3M). 4 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Eton Pharmaceuticals Inc.
- CUSIP
- 29772L108
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 26 | $10.3M |
| Exits | 11 | $14.0M |
All 13F filers, Q4 2024 → Q1 2025: 2,789,784 shares bought and 1,802,066 shares sold, net +987,718 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 86 holders
| Opaleye Management Inc. | 8.45% | No change | 2,852,070 | $37.0M |
| EcoR1 Capital, LLC | 1.50% | Add +6.0% | 1,939,288 | $25.2M |
| Nantahala Capital Management, LLC | 1.26% | Add +5.1% | 1,175,951 | $15.3M |
| Vanguard Group Inc. | 0.00% | Add +3.5% | 1,100,963 | $14.3M |
| Cannell Capital LLC | 3.03% | Add +81.3% | 691,367 | $9.0M |
| Westside Investment Management, Inc. | 1.37% | Reduce -14.2% | 493,650 | $6.4M |
| National Philanthropic Trust | 0.10% | No change | 492,112 | $6.4M |
| Susquehanna International Group, LLP | 0.01% | Add +133.4% | 448,804 | $5.8M |
| Acadian Asset Management LLC | 0.01% | Add +61.9% | 402,428 | $5.2M |
| Millennium Management | 0.00% | Add +156.3% | 355,929 | $4.6M |
| BlackRock, Inc. | 0.00% | Add +8.7% | 345,360 | $4.5M |
| Stifel Financial Corp. | 0.00% | New | 319,990 | $4.2M |
| Geode Capital Management, LLC | 0.00% | Add +11.0% | 298,248 | $3.9M |
| Renaissance Technologies | 0.01% | Add +41.9% | 274,000 | $3.6M |
| Aristides Capital LLC | 1.17% | No change | 241,587 | $3.1M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.01% | Add +8.2% | 232,532 | $3.0M |
| Thompson Siegel & Walmsley LLC | 0.04% | Add +48.3% | 189,863 | $2.5M |
| Goldman Sachs Group Inc. | 0.00% | Add +34.9% | 175,220 | $2.3M |
| Prelude Capital Management, LLC | 0.22% | Add +598.9% | 169,436 | $2.2M |
| Morgan Stanley | 0.00% | Add +1016.7% | 147,332 | $1.9M |
| Mink Brook Asset Management LLC | 1.93% | Reduce -69.0% | 141,488 | $1.8M |
| Bridgeway Capital Management, LLC | 0.04% | Reduce -43.4% | 135,270 | $1.8M |
| State Street Corp. | 0.00% | Add +8.4% | 114,236 | $1.5M |
| JPMorgan Chase & Co. | 0.00% | Add +117.7% | 113,113 | $1.5M |
| Cubist Systematic Strategies, LLC | 0.02% | Add +138.7% | 103,200 | $1.3M |
| Jane Street Group, LLC | 0.00% | Add +49.1% | 95,919 | $1.2M |
| UBS Group AG | 0.00% | Reduce -29.3% | 95,748 | $1.2M |
| Qube Research & Technologies Ltd | 0.00% | Reduce -7.8% | 86,848 | $1.1M |
| Northern Trust Corp. | 0.00% | Reduce -2.9% | 84,450 | $1.1M |
| Two Sigma Investments, LP | 0.00% | Reduce -26.8% | 82,355 | $1.1M |
| Raymond James Financial Inc. | 0.00% | Add +608.3% | 78,213 | $1.0M |
| Informed Momentum Co LLC | 0.17% | Reduce -18.1% | 77,833 | $1.0M |
| Bank of New York Mellon Corp | 0.00% | No change | 74,246 | $964K |
| Squarepoint Ops LLC | 0.00% | New | 64,795 | $841K |
| Anchor Capital Advisors LLC | 0.02% | Reduce -0.4% | 60,179 | $781K |
| HRT Financial LP | 0.00% | New | 57,235 | $742K |
| Jacobs Levy Equity Management, Inc. | 0.00% | New | 54,275 | $704K |
| Two Sigma Advisers, LP | 0.00% | Add +6.8% | 53,100 | $689K |
| Balyasny Asset Management L.P. | 0.00% | Add +323.7% | 50,205 | $652K |
| Barclays PLC | 0.00% | Reduce -18.6% | 44,661 | $580K |
| BNP Paribas Financial Markets | 0.00% | Add +11133.4% | 39,317 | $510K |
| OMERS ADMINISTRATION Corp | 0.00% | Reduce -6.9% | 35,300 | $458K |
| Blair William & Co. | 0.00% | No change | 34,900 | $453K |
| State of Wyoming | 0.05% | New | 26,443 | $343K |
| PDT Partners, LLC | 0.02% | New | 25,755 | $334K |
| Wellington Management Group LLP | 0.00% | New | 25,283 | $328K |
| Citadel Advisors | 0.00% | New | 24,492 | $318K |
| Schonfeld Strategic Advisors LLC | 0.00% | Reduce -73.0% | 24,213 | $314K |
| Man Group plc | 0.00% | New | 22,404 | $291K |
| Jain Global LLC | 0.01% | New | 22,401 | $291K |
| Essex Investment Management Co. LLC | 0.06% | Reduce -16.5% | 20,419 | $265K |
| Diametric Capital, LP | 0.30% | New | 19,597 | $254K |
| Hillsdale Investment Management Inc. | 0.01% | Add +11.7% | 18,983 | $246K |
| Envestnet Asset Management Inc. | 0.00% | Reduce -2.4% | 17,316 | $225K |
| ExodusPoint Capital Management, LP | 0.00% | New | 17,102 | $222K |
| CHICAGO TRUST Co NA | 0.04% | No change | 16,700 | $217K |
| Quantessence Capital LLC | 0.05% | New | 16,590 | $215K |
| Jump Financial, LLC | 0.00% | Reduce -34.0% | 16,303 | $212K |
| State of Tennessee, Department of Treasury | 0.00% | New | 13,950 | $181K |
| LMR Partners LLP | 0.00% | New | 13,574 | $176K |
| Y-Intercept (Hong Kong) Ltd | 0.01% | New | 13,400 | $174K |
| Charles Schwab Investment Management Inc. | 0.00% | Add +0.1% | 13,247 | $172K |
| Bank of America Corp. | 0.00% | Add +12.1% | 12,440 | $161K |
| XTX Topco Ltd | 0.01% | Reduce -19.5% | 11,797 | $153K |
| Quantum Private Wealth, LLC | 0.06% | No change | 11,500 | $149K |
| Cannon Global Investment Management, LLC | 0.41% | New | 11,400 | $148K |
| Point72 Asia (Singapore) Pte. Ltd. | 0.04% | Add +2.2% | 10,795 | $140K |
| Brevan Howard Capital Management LP | 0.00% | New | 10,693 | $139K |
| Verition Fund Management LLC | 0.00% | New | 10,189 | $132K |
| Jefferies Financial Group Inc. | 0.00% | No change | 10,000 | $130K |
| Quantbot Technologies LP | 0.00% | New | 7,794 | $101K |
| Steward Partners Investment Advisory, LLC | 0.00% | New | 7,499 | $97K |
| Simplex Trading, LLC | 0.00% | Reduce -87.7% | 4,472 | $58K |
| AlphaQuest LLC | 0.01% | New | 4,118 | $53K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -53.8% | 2,971 | $39K |
| Point72 (DIFC) Ltd | 0.00% | Add +24.9% | 1,800 | $23K |
| Royal Bank of Canada | 0.00% | Add +116.6% | 1,629 | $22K |
| Point72 Asset Management | 0.00% | New | 1,500 | $19K |
| Truvestments Capital LLC | 0.00% | No change | 1,183 | $15K |
| Wells Fargo & Company | 0.00% | Reduce -25.0% | 750 | $10K |
| Federated Hermes, Inc. | 0.00% | Reduce -50.7% | 686 | $9K |
| Group One Trading LLC | 0.00% | New | 634 | $8K |
| SBI Securities Co., Ltd. | 0.00% | Reduce -29.1% | 100 | $1K |
| Caitong International Asset Management Co., Ltd | 0.00% | New | 77 | $999 |
| FMR LLC | 0.00% | New | 10 | $130 |
| Citigroup Inc. | 0.00% | Reduce -100.0% | 1 | $13 |
"% of holder's portfolio" is ETON's weight in each manager's 13F, not the share of Eton Pharmaceuticals Inc. the manager owns.