Fulcrum TherapeuticsFULC
13F holders, Q3 2025 (September 30)129holders +7
26new positions
17sold out
4famous investors
$9.21avg. 13F price*
At the end of Q3 2025, 129 institutions reported holding Fulcrum Therapeutics Inc. (FULC) in their 13F filings, up 7 from Q2 2025. 26 opened new positions and 17 sold out. The largest holders were Ra Capital Management, L.P. ($94.1M), Montanova Capital, LLC ($49.5M) and TCG Crossover Management, LLC ($48.3M). 4 famous investors held it, including David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).
- Company
- Fulcrum Therapeutics Inc.
- CUSIP
- 359616109
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 26 | $8.9M |
| Exits | 17 | $12.7M |
All 13F filers, Q2 2025 → Q3 2025: 6,697,390 shares bought and 7,261,561 shares sold, net −564,171 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 129 holders
| Ra Capital Management, L.P. | 1.16% | No change | 10,229,099 | $94.1M |
| Montanova Capital, LLC | 1.50% | Add +5.9% | 5,381,000 | $49.5M |
| TCG Crossover Management, LLC | 2.38% | No change | 5,250,000 | $48.3M |
| Nantahala Capital Management, LLC | 2.66% | Add +8.9% | 4,670,784 | $43.0M |
| BlackRock, Inc. | 0.00% | Reduce -15.3% | 3,706,750 | $34.1M |
| Vanguard Group Inc. | 0.00% | Reduce -4.7% | 2,999,464 | $27.6M |
| Adage Capital Partners Gp, L.L.C. | 0.04% | Reduce -47.0% | 2,432,000 | $22.4M |
| Balyasny Asset Management L.P. | 0.03% | Add +8.4% | 1,450,480 | $13.3M |
| D. E. Shaw & Co. | 0.01% | Add +23.2% | 1,449,423 | $13.3M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -5.3% | 1,299,308 | $12.0M |
| Ikarian Capital, LLC | 2.40% | Add +200.8% | 1,289,225 | $11.9M |
| State Street Corp. | 0.00% | Reduce -12.7% | 1,063,207 | $9.8M |
| Geode Capital Management, LLC | 0.00% | Reduce -15.8% | 1,004,051 | $9.2M |
| Royal Bank of Canada | 0.00% | Add +23633.7% | 1,000,849 | $9.2M |
| Citadel Advisors | 0.01% | Add +414.1% | 854,556 | $7.9M |
| Boothbay Fund Management, LLC | 0.17% | Add +379.9% | 678,414 | $6.2M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -48.7% | 586,351 | $5.4M |
| Northern Trust Corp. | 0.00% | Reduce -7.1% | 568,322 | $5.2M |
| Acadian Asset Management LLC | 0.01% | Reduce -4.0% | 540,641 | $5.0M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.01% | Add +12.1% | 384,138 | $3.5M |
| Schonfeld Strategic Advisors LLC | 0.02% | Add +79.2% | 366,303 | $3.4M |
| ADAR1 Capital Management, LLC | 0.31% | Add +540.3% | 341,612 | $3.1M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -14.0% | 333,483 | $3.1M |
| Jane Street Group, LLC | 0.00% | Add +1745.0% | 321,520 | $3.0M |
| UBS Group AG | 0.00% | Add +122.7% | 301,157 | $2.8M |
| Bessemer Group Inc. | 0.00% | No change | 286,988 | $2.6M |
| Deutsche Bank AG | 0.00% | Add +2.2% | 285,329 | $2.6M |
| Renaissance Technologies | 0.00% | Add +216.2% | 248,200 | $2.3M |
| Morgan Stanley | 0.00% | Reduce -22.4% | 243,835 | $2.2M |
| Braidwell LP | 0.08% | New | 219,488 | $2.0M |
| Wellington Management Group LLP | 0.00% | Add +41.9% | 179,358 | $1.7M |
| American Century Companies Inc. | 0.00% | Add +15.0% | 152,244 | $1.4M |
| Millennium Management | 0.00% | Add +42.7% | 150,867 | $1.4M |
| Bank of America Corp. | 0.00% | Add +220.1% | 147,211 | $1.4M |
| Aberdeen Group plc | 0.00% | Add +135.0% | 137,961 | $1.3M |
| Fiduciary Trust Co | 0.01% | No change | 136,555 | $1.3M |
| J. Goldman & Co LP | 0.05% | Add +100.0% | 135,000 | $1.2M |
| HRT Financial LP | 0.00% | New | 124,924 | $1.1M |
| Ameriprise Financial Inc. | 0.00% | New | 124,666 | $1.1M |
| Invesco Ltd. | 0.00% | Reduce -73.7% | 123,872 | $1.1M |
| Bank of New York Mellon Corp | 0.00% | Reduce -13.0% | 119,158 | $1.1M |
| Gsa Capital Partners LLP | 0.09% | Add +256.4% | 116,068 | $1.1M |
| Nuveen, LLC | 0.00% | Reduce -10.0% | 112,203 | $1.0M |
| Susquehanna Fundamental Investments, LLC | 0.04% | No change | 111,582 | $1.0M |
| Campbell & CO Investment Adviser LLC | 0.07% | New | 102,470 | $943K |
| Exome Asset Management LLC | 0.60% | Reduce -77.8% | 98,799 | $909K |
| Bridgeway Capital Management, LLC | 0.02% | Reduce -2.3% | 95,400 | $878K |
| Barclays PLC | 0.00% | Reduce -20.0% | 89,616 | $824K |
| Commonwealth Equity Services, LLC | 0.00% | No change | 83,428 | $768K |
| Simplify Asset Management Inc. | 0.02% | Add +13.8% | 83,234 | $766K |
| RBF Capital, LLC | 0.03% | No change | 80,506 | $741K |
| STRS Ohio | 0.00% | Add +3.7% | 77,900 | $717K |
| Alliancebernstein L.P. | 0.00% | No change | 74,590 | $686K |
| Jacobs Levy Equity Management, Inc. | 0.00% | Reduce -24.3% | 70,015 | $644K |
| Rhumbline Advisers | 0.00% | Reduce -16.7% | 69,372 | $638K |
| Summit Wealth Group LLC / Co. | 0.07% | New | 533 | $616K |
| Principal Financial Group Inc. | 0.00% | New | 66,550 | $612K |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 60,000 | $611K |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -4.5% | 65,892 | $607K |
| Franklin Resources Inc. | 0.00% | No change | 60,022 | $552K |
| Acuta Capital Partners, LLC | 0.54% | Reduce -4.2% | 57,141 | $526K |
| Susquehanna International Group, LLP | 0.00% | Reduce -46.1% | 53,571 | $493K |
| HSBC Holdings PLC | 0.00% | Add +8.6% | 53,806 | $474K |
| Fox Run Management, L.L.C. | 0.07% | New | 50,791 | $467K |
| AlphaQuest LLC | 0.02% | New | 35,375 | $325K |
| Wells Fargo & Company | 0.00% | Reduce -3.7% | 32,507 | $299K |
| Two Sigma Advisers, LP | 0.00% | Reduce -61.6% | 31,500 | $290K |
| Graham Capital Management, L.P. | 0.02% | Add +152.9% | 30,486 | $280K |
| Country Trust Bank | 0.01% | Reduce -0.5% | 30,041 | $276K |
| LMR Partners LLP | 0.01% | Reduce -40.0% | 30,000 | $276K |
| Prelude Capital Management, LLC | 0.02% | Reduce -79.9% | 28,832 | $265K |
| Bailard, Inc. | 0.01% | No change | 26,881 | $247K |
| MetLife Investment Management, LLC | 0.00% | Reduce -20.4% | 25,895 | $238K |
| Quantinno Capital Management LP | 0.00% | New | 24,649 | $227K |
| PharVision Advisers, LLC | 0.12% | New | 23,868 | $220K |
| Trexquant Investment LP | 0.00% | New | 21,015 | $193K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -32.0% | 20,006 | $184K |
| Matisse Capital | 0.08% | Reduce -28.6% | 18,630 | $171K |
| JPMorgan Chase & Co. | 0.00% | Reduce -30.9% | 18,069 | $166K |
| Squarepoint Ops LLC | 0.00% | Add +30.4% | 17,826 | $164K |
| Intech Investment Management LLC | 0.00% | Reduce -38.5% | 17,244 | $159K |
| Algert Global LLC | 0.00% | New | 16,550 | $152K |
| Legal & General Group Plc | 0.00% | Reduce -6.2% | 16,373 | $151K |
| WINTON GROUP Ltd | 0.01% | New | 16,212 | $149K |
| Brevan Howard Capital Management LP | 0.00% | New | 15,303 | $141K |
| Creative Planning | 0.00% | Reduce -15.3% | 14,354 | $132K |
| BNP Paribas Financial Markets | 0.00% | Add +137.9% | 14,274 | $131K |
| Alphabet Inc. | 0.01% | No change | 14,262 | $131K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -29.9% | 13,948 | $128K |
| Russell Investments Group, Ltd. | 0.00% | Add +47.5% | 13,731 | $126K |
| State of Wisconsin Investment Board | 0.00% | New | 13,666 | $126K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Add +1.7% | 13,168 | $121K |
| Sanctuary Advisors, LLC | 0.00% | New | 13,154 | $121K |
| New York State Common Retirement Fund | 0.00% | No change | 13,100 | $121K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +3.0% | 12,843 | $118K |
| Simplex Trading, LLC | 0.00% | Reduce -88.3% | 12,800 | $117K |
| Y-Intercept (Hong Kong) Ltd | 0.00% | New | 11,272 | $104K |
| Martingale Asset Management L P | 0.00% | Reduce -88.4% | 10,563 | $97K |
| Assetmark, Inc. | 0.00% | New | 9,611 | $88K |
| FMR LLC | 0.00% | Add +5.5% | 7,350 | $68K |
| Farther Finance Advisors, LLC | 0.00% | Add +108.3% | 7,112 | $65K |
| BIT Capital GmbH | 0.00% | Add +26.0% | 6,090 | $56K |
| Group One Trading LLC | 0.00% | Add +2.5% | 5,760 | $53K |
| Nisa Investment Advisors, LLC | 0.00% | No change | 4,281 | $39K |
| Quarry LP | 0.01% | New | 3,774 | $35K |
| Ameritas Investment Partners, Inc. | 0.00% | Reduce -40.8% | 3,598 | $33K |
| California State Teachers Retirement System | 0.00% | Add +0.1% | 3,334 | $31K |
| Summit Securities Group LLC | 0.01% | New | 2,917 | $27K |
| Sterling Capital Management LLC | 0.00% | Add +105.1% | 2,746 | $25K |
| Macquarie Group Ltd. | 0.00% | New | 2,495 | $23K |
| Amalgamated Bank | 0.00% | No change | 2,147 | $20K |
| IFP Advisors, Inc | 0.00% | Add +22.9% | 1,976 | $18K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -70.0% | 1,910 | $18K |
| Versant Capital Management, Inc | 0.00% | New | 1,800 | $17K |
| PNC Financial Services Group, Inc. | 0.00% | Reduce -2.2% | 1,417 | $13K |
| Citigroup Inc. | 0.00% | Reduce -96.6% | 718 | $7K |
| National Bank of Canada | 0.00% | Reduce -9.5% | 428 | $4K |
| Rise Advisors, LLC | 0.00% | No change | 348 | $3K |
| Federated Hermes, Inc. | 0.00% | New | 328 | $3K |
| Optiver Holding B.V. | 0.00% | New | 322 | $3K |
| Physician Wealth Advisors, Inc. | 0.00% | No change | 283 | $3K |
| Cwm, LLC | 0.00% | Add +7.6% | 199 | $2K |
| EverSource Wealth Advisors, LLC | 0.00% | Reduce -6.4% | 204 | $2K |
| Rialto Wealth Management, LLC | 0.00% | No change | 159 | $1K |
| Osaic Holdings, Inc. | 0.00% | No change | 90 | $828 |
| SBI Securities Co., Ltd. | 0.00% | Add +7.7% | 28 | $258 |
| True Wealth Design, LLC | 0.00% | No change | 16 | $148 |
| Clearstead Advisors, LLC | 0.00% | New | 4 | $37 |
| Essential Partners LLC | 0.00% | New | 1 | $9 |
"% of holder's portfolio" is FULC's weight in each manager's 13F, not the share of Fulcrum Therapeutics Inc. the manager owns.