Fulcrum TherapeuticsFULC
13F holders, Q4 2025 (December 31)172holders +43
56new positions
16sold out
6famous investors
$11.31avg. 13F price*
At the end of Q4 2025, 172 institutions reported holding Fulcrum Therapeutics Inc. (FULC) in their 13F filings, up 43 from Q3 2025. 56 opened new positions and 16 sold out. The largest holders were Montanova Capital, LLC ($74.2M), Ra Capital Management, L.P. ($68.5M) and TCG Crossover Management, LLC ($59.4M). 6 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Fulcrum Therapeutics Inc.
- CUSIP
- 359616109
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 56 | $126.1M |
| Exits | 16 | $6.8M |
All 13F filers, Q3 2025 → Q4 2025: 21,378,020 shares bought and 9,560,500 shares sold, net +11,817,520 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 172 holders
| Montanova Capital, LLC | 1.85% | Add +21.9% | 6,561,111 | $74.2M |
| Ra Capital Management, L.P. | 0.70% | Reduce -40.8% | 6,053,960 | $68.5M |
| TCG Crossover Management, LLC | 1.97% | No change | 5,250,000 | $59.4M |
| Nantahala Capital Management, LLC | 2.90% | Reduce -8.1% | 4,293,346 | $48.6M |
| BlackRock, Inc. | 0.00% | Add +15.0% | 4,263,761 | $48.2M |
| Vanguard Group Inc. | 0.00% | Add +18.7% | 3,559,552 | $40.3M |
| Braidwell LP | 1.33% | Add +1294.7% | 3,061,222 | $34.6M |
| Point72 Asset Management | 0.04% | New | 2,398,232 | $27.1M |
| Siren, L.L.C. | 0.66% | New | 1,950,000 | $22.1M |
| D. E. Shaw & Co. | 0.02% | Add +32.0% | 1,913,755 | $21.6M |
| First Turn Management, LLC | 2.45% | New | 1,892,683 | $21.4M |
| GSK plc | 2.53% | — | 1,785,714 | $20.2M |
| Adage Capital Partners Gp, L.L.C. | 0.03% | Reduce -30.1% | 1,700,000 | $19.2M |
| Ikarian Capital, LLC | 2.01% | Add +6.7% | 1,375,472 | $15.6M |
| Aberdeen Group plc | 0.02% | Add +809.0% | 1,254,027 | $14.2M |
| ADAR1 Capital Management, LLC | 1.06% | Add +267.0% | 1,253,749 | $14.2M |
| Citadel Advisors | 0.01% | Add +41.2% | 1,207,004 | $13.7M |
| Geode Capital Management, LLC | 0.00% | Add +10.1% | 1,105,813 | $12.5M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -19.1% | 1,051,124 | $11.9M |
| State Street Corp. | 0.00% | Reduce -5.4% | 1,005,345 | $11.4M |
| Balyasny Asset Management L.P. | 0.02% | Reduce -33.1% | 970,439 | $11.0M |
| Vestal Point Capital, LP | 0.39% | New | 950,000 | $10.7M |
| Great Point Partners LLC | 2.93% | New | 800,000 | $9.0M |
| Acadian Asset Management LLC | 0.01% | Add +36.3% | 736,740 | $8.3M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.02% | Add +51.6% | 582,377 | $6.6M |
| Northern Trust Corp. | 0.00% | Reduce -2.8% | 552,220 | $6.2M |
| Boothbay Fund Management, LLC | 0.16% | Reduce -23.7% | 517,526 | $5.9M |
| Jane Street Group, LLC | 0.01% | Add +53.6% | 493,750 | $5.6M |
| Invesco Ltd. | 0.00% | Add +236.8% | 417,189 | $4.7M |
| Silverarc Capital Management, LLC | 0.65% | New | 394,650 | $4.5M |
| Qube Research & Technologies Ltd | 0.01% | New | 392,489 | $4.4M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +16.6% | 388,896 | $4.4M |
| Sio Capital Management, LLC | 0.72% | New | 382,000 | $4.3M |
| Trexquant Investment LP | 0.04% | Add +1591.9% | 355,547 | $4.0M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -44.8% | 323,879 | $3.7M |
| Deutsche Bank AG | 0.00% | Add +0.6% | 287,096 | $3.2M |
| Bessemer Group Inc. | 0.01% | No change | 286,988 | $3.2M |
| Driehaus Capital Management LLC | 0.02% | New | 243,388 | $2.8M |
| Bank of America Corp. | 0.00% | Add +57.0% | 231,177 | $2.6M |
| Catalio Capital Management, LP | 0.40% | New | 201,301 | $2.3M |
| Nicholas Investment Partners, LP | 0.17% | New | 182,961 | $2.1M |
| Wells Fargo & Company | 0.00% | Add +411.9% | 166,395 | $1.9M |
| Morgan Stanley | 0.00% | Reduce -32.1% | 165,623 | $1.9M |
| Simplify Asset Management Inc. | 0.03% | Add +91.8% | 159,674 | $1.8M |
| American Century Companies Inc. | 0.00% | Add +3.6% | 157,672 | $1.8M |
| Wellington Management Group LLP | 0.00% | Reduce -18.4% | 146,427 | $1.7M |
| SummitTX Capital, L.P. | 0.05% | New | 138,143 | $1.6M |
| Fiduciary Trust Co | 0.02% | No change | 136,555 | $1.5M |
| Barclays PLC | 0.00% | Add +47.9% | 132,541 | $1.5M |
| Bank of New York Mellon Corp | 0.00% | Reduce -1.9% | 116,906 | $1.3M |
| Nuveen, LLC | 0.00% | No change | 112,203 | $1.3M |
| Walleye Capital LLC | 0.01% | New | 108,434 | $1.2M |
| UBS Group AG | 0.00% | Reduce -65.8% | 102,967 | $1.2M |
| Marshall Wace, LLP | 0.00% | New | 102,921 | $1.2M |
| Ameriprise Financial Inc. | 0.00% | Reduce -19.2% | 100,675 | $1.1M |
| Maven Securities LTD | 0.14% | New | 100,000 | $1.1M |
| Gsa Capital Partners LLP | 0.10% | Reduce -14.1% | 99,709 | $1.1M |
| Principal Financial Group Inc. | 0.00% | Add +46.8% | 97,688 | $1.1M |
| Jump Financial, LLC | 0.01% | New | 92,200 | $1.0M |
| Exome Asset Management LLC | 0.51% | Reduce -6.8% | 92,055 | $1.0M |
| Susquehanna International Group, LLP | 0.00% | Add +64.1% | 87,930 | $994K |
| State of Wisconsin Investment Board | 0.00% | Add +533.0% | 86,499 | $978K |
| RBF Capital, LLC | 0.04% | No change | 80,506 | $911K |
| Verition Fund Management LLC | 0.00% | New | 74,691 | $845K |
| Superstring Capital Management LP | 0.44% | New | 72,060 | $815K |
| Citigroup Inc. | 0.00% | Add +9245.7% | 67,102 | $759K |
| Y-Intercept (Hong Kong) Ltd | 0.02% | Add +491.9% | 66,716 | $755K |
| Legato Capital Management LLC | 0.06% | New | 66,347 | $750K |
| Squarepoint Ops LLC | 0.00% | Add +269.4% | 65,852 | $745K |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -3.2% | 63,760 | $722K |
| Integrated Quantitative Investments LLC | 0.15% | New | 62,522 | $707K |
| Informed Momentum Co LLC | 0.08% | New | 61,620 | $697K |
| Atom Investors LP | 0.05% | New | 60,595 | $685K |
| New York State Common Retirement Fund | 0.00% | Add +340.6% | 57,725 | $653K |
| Rhumbline Advisers | 0.00% | Reduce -19.7% | 55,713 | $630K |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 60,000 | $617K |
| Millennium Management | 0.00% | Reduce -63.9% | 54,431 | $616K |
| XTX Topco Ltd | 0.02% | New | 51,802 | $586K |
| KVP Capital Advisors, LP | 0.58% | — | 50,000 | $566K |
| Seven Grand Managers, LLC | 0.04% | New | 50,000 | $566K |
| Burkehill Global Management, LP | 0.04% | New | 50,000 | $566K |
| Brevan Howard Capital Management LP | 0.01% | Add +219.6% | 48,900 | $559K |
| STRS Ohio | 0.00% | Reduce -36.7% | 49,300 | $558K |
| Graham Capital Management, L.P. | 0.03% | Add +59.0% | 48,464 | $548K |
| Franklin Resources Inc. | 0.00% | Reduce -26.3% | 44,249 | $500K |
| HSBC Holdings PLC | 0.00% | Reduce -19.6% | 43,262 | $498K |
| Jain Global LLC | 0.00% | New | 41,260 | $467K |
| Commonwealth Equity Services, LLC | 0.00% | Reduce -52.0% | 40,000 | $452K |
| Sei Investments Co. | 0.00% | New | 37,511 | $424K |
| Campbell & CO Investment Adviser LLC | 0.02% | Reduce -65.3% | 35,601 | $403K |
| Group One Trading LLC | 0.01% | Add +503.3% | 34,750 | $393K |
| Axq Capital, LP | 0.08% | New | 31,545 | $357K |
| Woodline Partners LP | 0.00% | New | 30,793 | $348K |
| Two Sigma Advisers, LP | 0.00% | Reduce -3.2% | 30,500 | $345K |
| Country Trust Bank | 0.01% | No change | 30,041 | $340K |
| LMR Partners LLP | 0.00% | No change | 30,000 | $339K |
| Quantinno Capital Management LP | 0.00% | Add +18.7% | 29,264 | $331K |
| Prelude Capital Management, LLC | 0.02% | No change | 28,832 | $326K |
| Fox Run Management, L.L.C. | 0.04% | Reduce -49.7% | 25,568 | $289K |
| MetLife Investment Management, LLC | 0.00% | Reduce -12.3% | 22,714 | $257K |
"% of holder's portfolio" is FULC's weight in each manager's 13F, not the share of Fulcrum Therapeutics Inc. the manager owns.