Disc MedicineIRON
13F holders, Q2 2025 (June 30)At the end of Q2 2025, 151 institutions reported holding Disc Medicine Inc. (IRON) in their 13F filings, down 6 from Q1 2025. 24 opened new positions and 31 sold out. The largest holders were FMR LLC ($171.9M), Atlas Venture Life Science Advisors, LLC ($126.3M) and BlackRock, Inc. ($108.3M). 3 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Cliff Asness (0.0% of AQR Capital Management's portfolio).
- Company
- Disc Medicine Inc.
- CUSIP
- 254604101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 24 | $45.4M |
| Exits | 31 | $53.9M |
All 13F filers, Q1 2025 → Q2 2025: 3,984,524 shares bought and 3,069,111 shares sold, net +915,413 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 151 holders
| FMR LLC | 0.01% | Add +0.7% | 3,245,710 | $171.9M |
| Atlas Venture Life Science Advisors, LLC | 19.07% | No change | 2,384,456 | $126.3M |
| BlackRock, Inc. | 0.00% | Reduce -2.4% | 2,044,827 | $108.3M |
| Frazier Life Sciences Management, L.P. | 3.51% | Reduce -5.7% | 1,654,834 | $87.6M |
| Ra Capital Management, L.P. | 1.41% | No change | 1,577,106 | $83.5M |
| Janus Henderson Group PLC | 0.04% | Add +9.2% | 1,553,961 | $82.3M |
| T. Rowe Price Associates Inc. | 0.01% | Add +11.6% | 1,515,625 | $80.3M |
| Wellington Management Group LLP | 0.01% | Reduce -38.9% | 1,432,090 | $75.8M |
| Orbimed Advisors LLC | 1.88% | No change | 1,415,020 | $74.9M |
| Vanguard Group Inc. | 0.00% | Add +7.0% | 1,396,736 | $74.0M |
| Paradigm Biocapital Advisors LP | 2.74% | No change | 1,210,971 | $64.1M |
| Siren, L.L.C. | 3.01% | Add +2.6% | 1,099,401 | $58.2M |
| State Street Corp. | 0.00% | Add +1.2% | 929,768 | $49.2M |
| Deerfield Management Company, L.P. | 0.99% | Add +17.5% | 919,403 | $48.7M |
| Woodline Partners LP | 0.24% | Add +72.6% | 866,955 | $45.9M |
| JPMorgan Chase & Co. | 0.00% | Add +11.1% | 843,616 | $44.7M |
| Logos Global Management LP | 4.95% | Add +77.5% | 700,000 | $37.1M |
| Geode Capital Management, LLC | 0.00% | Add +4.7% | 598,589 | $31.7M |
| Bain Capital Life Sciences Investors, LLC | 3.87% | Reduce -40.7% | 583,500 | $30.9M |
| TCG Crossover Management, LLC | 2.81% | No change | 465,257 | $24.6M |
| Adage Capital Partners Gp, L.L.C. | 0.04% | Add +50.0% | 450,000 | $23.8M |
| Armistice Capital, LLC | 0.88% | No change | 436,000 | $23.1M |
| Saturn V Capital Management LP | 8.50% | Reduce -23.6% | 396,115 | $21.0M |
| Baker Bros. Advisors LP | 0.17% | Add +337.4% | 337,050 | $17.9M |
| Eventide Asset Management, LLC | 0.29% | Add +69.4% | 308,030 | $16.3M |
| First Turn Management, LLC | 2.96% | New | 299,464 | $15.9M |
| Foresite Capital Management V, LLC | 19.62% | No change | 299,069 | $15.8M |
| Nantahala Capital Management, LLC | 1.08% | Add +94.0% | 287,800 | $15.2M |
| Sio Capital Management, LLC | 6.05% | Add +287.4% | 284,787 | $15.1M |
| Checkpoint Capital L.P. | 6.54% | Add +8.9% | 265,000 | $14.0M |
| Goldman Sachs Group Inc. | 0.00% | Add +72.7% | 225,856 | $12.0M |
| Northern Trust Corp. | 0.00% | Add +4.9% | 219,095 | $11.6M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +4.9% | 204,241 | $10.8M |
| Victory Capital Management Inc. | 0.01% | Add +2.1% | 197,824 | $10.5M |
| Dimensional Fund Advisors LP | 0.00% | Add +38.4% | 192,856 | $10.2M |
| Opaleye Management Inc. | 2.04% | Add +119.3% | 186,418 | $9.9M |
| Bank of America Corp. | 0.00% | Add +213.8% | 168,822 | $8.9M |
| Palo Alto Investors LP | 1.64% | New | 145,691 | $7.7M |
| UBS Group AG | 0.00% | Add +100.4% | 145,549 | $7.7M |
| Ensign Peak Advisors, Inc | 0.01% | Add +95.2% | 141,545 | $7.5M |
| Vestal Point Capital, LP | 0.39% | New | 140,000 | $7.4M |
| Blue Owl Capital Holdings LP | 2.10% | Reduce -12.8% | 122,260 | $6.5M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +25.9% | 121,584 | $6.4M |
| Ameriprise Financial Inc. | 0.00% | Add +79.0% | 121,520 | $6.4M |
| Morgan Stanley | 0.00% | Reduce -35.0% | 110,679 | $5.9M |
| Renaissance Technologies | 0.01% | Reduce -49.6% | 96,420 | $5.1M |
| Zimmer Partners, LP | 0.11% | Add +110.2% | 90,163 | $4.8M |
| Barclays PLC | 0.00% | Add +89.4% | 86,558 | $4.6M |
| Raymond James Financial Inc. | 0.00% | Add +3.9% | 86,487 | $4.6M |
| Schroder Investment Management Group | 0.00% | Reduce -5.5% | 82,451 | $4.5M |
| Susquehanna International Group, LLP | 0.01% | Add +7.1% | 75,997 | $4.0M |
| Patient Square Capital LP | 1.41% | Reduce -10.8% | 74,000 | $3.9M |
| Bank of New York Mellon Corp | 0.00% | Add +12.6% | 71,502 | $3.8M |
| Exome Asset Management LLC | 2.68% | Reduce -0.5% | 61,356 | $3.2M |
| ExodusPoint Capital Management, LP | 0.04% | Add +327.2% | 57,945 | $3.1M |
| Nicholas Investment Partners, LP | 0.29% | New | 54,445 | $2.9M |
| TD Asset Management Inc | 0.00% | Add +25.0% | 53,048 | $2.8M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +27.7% | 51,836 | $2.7M |
| Nuveen, LLC | 0.00% | Reduce -55.4% | 50,270 | $2.7M |
| Swiss National Bank | 0.00% | Add +19.5% | 42,900 | $2.3M |
| Rhumbline Advisers | 0.00% | Add +11.2% | 35,755 | $1.9M |
| Aberdeen Group plc | 0.00% | New | 32,061 | $1.7M |
| Rafferty Asset Management, LLC | 0.01% | Reduce -7.5% | 31,489 | $1.7M |
| PFM Health Sciences, LP | 0.14% | New | 30,799 | $1.6M |
| Catalio Capital Management, LP | 0.34% | New | 30,661 | $1.6M |
| Bollard Group LLC | 0.04% | New | 30,635 | $1.6M |
| PNC Financial Services Group, Inc. | 0.00% | Add +6.1% | 25,140 | $1.3M |
| Atle Fund Management AB | 0.56% | New | 24,652 | $1.3M |
| Alliancebernstein L.P. | 0.00% | Add +14.6% | 24,140 | $1.3M |
| Legal & General Group Plc | 0.00% | Add +18.0% | 24,097 | $1.3M |
| Royal Bank of Canada | 0.00% | Add +1786.4% | 22,599 | $1.2M |
| Wells Fargo & Company | 0.00% | Reduce -1.6% | 22,461 | $1.2M |
| Millennium Management | 0.00% | Reduce -80.1% | 21,593 | $1.1M |
| California State Teachers Retirement System | 0.00% | Add +0.5% | 20,250 | $1.1M |
| Voloridge Investment Management, LLC | 0.00% | New | 19,726 | $1.0M |
| Alps Advisors Inc. | 0.01% | Reduce -26.9% | 18,626 | $986K |
| Prelude Capital Management, LLC | 0.09% | Reduce -0.2% | 18,156 | $962K |
| New York State Common Retirement Fund | 0.00% | Add +168.5% | 16,852 | $892K |
| Invesco Ltd. | 0.00% | Add +21.6% | 16,817 | $891K |
| Deutsche Bank AG | 0.00% | Add +13.7% | 16,717 | $885K |
| Citigroup Inc. | 0.00% | Reduce -62.5% | 16,109 | $853K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -0.6% | 15,041 | $799K |
| MetLife Investment Management, LLC | 0.00% | Add +10.4% | 14,854 | $787K |
| Harvest Investment Services, LLC | 0.17% | Reduce -6.9% | 14,316 | $758K |
| Walleye Capital LLC | 0.01% | Reduce -36.3% | 14,064 | $745K |
| AQR Capital Management | 0.00% | New | 13,649 | $723K |
| State of Wisconsin Investment Board | 0.00% | Add +7.6% | 12,889 | $683K |
| Teachers Retirement System of the State of Kentucky | 0.01% | Reduce -12.2% | 12,851 | $681K |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0.02% | Reduce -9.6% | 12,317 | $652K |
| Intech Investment Management LLC | 0.01% | Add +11.6% | 12,222 | $647K |
| Bank of Montreal | 0.00% | Add +87.8% | 10,988 | $582K |
| Lion Point Capital, LP | 3.81% | No change | 10,600 | $561K |
| First Trust Advisors LP | 0.00% | New | 10,246 | $543K |
| Y-Intercept (Hong Kong) Ltd | 0.01% | New | 9,382 | $497K |
| State Board of Administration of Florida Retirement System | 0.00% | Add +125.4% | 9,129 | $483K |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | Add +15.4% | 7,376 | $391K |
| Sofinnova Investments, Inc. | 0.03% | Reduce -2.3% | 7,312 | $387K |
| Legato Capital Management LLC | 0.05% | New | 7,228 | $383K |
| China Universal Asset Management Co., Ltd. | 0.03% | Add +0.3% | 6,956 | $368K |
| HighVista Strategies LLC | 0.13% | Add +4.3% | 6,733 | $357K |
| Profund Advisors LLC | 0.01% | Reduce -6.2% | 6,714 | $356K |
| Voya Investment Management LLC | 0.00% | Add +12.5% | 6,695 | $355K |
| Arizona State Retirement System | 0.00% | Add +22.9% | 6,534 | $346K |
| ProShare Advisors LLC | 0.00% | Reduce -2.4% | 6,345 | $336K |
| Teacher Retirement System of Texas | 0.00% | Add +21.2% | 6,017 | $319K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +12.3% | 5,490 | $291K |
| BNP Paribas Financial Markets | 0.00% | Reduce -54.3% | 4,703 | $249K |
| KLP Kapitalforvaltning As | 0.00% | Add +24.3% | 4,600 | $244K |
| DNB Asset Management AS | 0.00% | New | 4,583 | $243K |
| Fiduciary Trust Co | 0.00% | No change | 4,051 | $215K |
| Tower Research Capital LLC (TRC) | 0.01% | Add +383.0% | 3,975 | $211K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Reduce -0.9% | 3,047 | $161K |
| Ameritas Investment Partners, Inc. | 0.00% | Add +8.9% | 2,515 | $133K |
| Meeder Asset Management Inc. | 0.01% | New | 2,244 | $119K |
| STRS Ohio | 0.00% | Reduce -68.6% | 2,200 | $117K |
| Virtus Investment Advisers, LLC | 0.03% | Reduce -30.2% | 1,784 | $94K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +15.6% | 1,338 | $71K |
| US Bancorp \de | 0.00% | Reduce -2.0% | 1,179 | $62K |
| Avanza Fonder AB | 0.00% | New | 1,083 | $57K |
| Cwm, LLC | 0.00% | Add +213.5% | 1,044 | $55K |
| Amalgamated Bank | 0.00% | No change | 787 | $42K |
| GF Fund Management Co. LTD. | 0.00% | No change | 762 | $40K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 730 | $39K |
| Steward Partners Investment Advisory, LLC | 0.00% | Add +1.5% | 533 | $28K |
| AlphaQuest LLC | 0.00% | No change | 327 | $17K |
| iA Global Asset Management Inc. | 0.00% | New | 322 | $17K |
| Nisa Investment Advisors, LLC | 0.00% | Add +250.6% | 284 | $15K |
| Osaic Holdings, Inc. | 0.00% | New | 270 | $14K |
| GAMMA Investing LLC | 0.00% | Reduce -4.0% | 240 | $13K |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | New | 202 | $11K |
| Simplex Trading, LLC | 0.00% | Reduce -89.2% | 199 | $10K |
| Clearstead Advisors, LLC | 0.00% | Add +221.7% | 148 | $8K |
| Daiwa Securities Group Inc. | 0.00% | No change | 113 | $6K |
| Larson Financial Group LLC | 0.00% | New | 109 | $6K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +620.0% | 72 | $4K |
| Sterling Capital Management LLC | 0.00% | Reduce -83.0% | 60 | $3K |
| Rothschild Investment LLC | 0.00% | No change | 45 | $2K |
| Comerica Bank | 0.00% | Add +47.1% | 25 | $1K |
| Parkside Financial Bank & Trust | 0.00% | New | 20 | $1K |
| Versant Capital Management, Inc | 0.00% | New | 19 | $1K |
| Bessemer Group Inc. | 0.00% | No change | 12 | $1K |
| Russell Investments Group, Ltd. | 0.00% | Add +60.0% | 16 | $847 |
| Assetmark, Inc. | 0.00% | No change | 12 | $636 |
| J.Safra Asset Management Corp | 0.00% | No change | 6 | $318 |
| SBI Securities Co., Ltd. | 0.00% | No change | 6 | $318 |
| Essential Partners LLC | 0.00% | — | 4 | $212 |
| Allworth Financial LP | 0.00% | New | 4 | $212 |
| Caitong International Asset Management Co., Ltd | 0.00% | Reduce -99.7% | 3 | $159 |
| Global Retirement Partners, LLC | 0.00% | — | 3 | $159 |
| True Wealth Design, LLC | 0.00% | Reduce -85.7% | 1 | $53 |
| Covestor Ltd | 0.00% | No change | 2 | $0 |
"% of holder's portfolio" is IRON's weight in each manager's 13F, not the share of Disc Medicine Inc. the manager owns.