Disc MedicineIRON

13F holders, Q2 2025 (June 30)
151holders −6
24new positions
31sold out
3famous investors
$52.96avg. 13F price*

At the end of Q2 2025, 151 institutions reported holding Disc Medicine Inc. (IRON) in their 13F filings, down 6 from Q1 2025. 24 opened new positions and 31 sold out. The largest holders were FMR LLC ($171.9M), Atlas Venture Life Science Advisors, LLC ($126.3M) and BlackRock, Inc. ($108.3M). 3 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Cliff Asness (0.0% of AQR Capital Management's portfolio).

Company
Disc Medicine Inc.
CUSIP
254604101
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150200250 Q1 2024: 130Q1 2024Q2 2024: 121Q2 2024Q3 2024: 132Q3 2024Q4 2024: 152Q4 2024Q1 2025: 157Q1 2025Q2 2025: 151Q2 2025Q3 2025: 168Q3 2025Q4 2025: 197Q4 2025Q1 2026: 203Q1 2026Q2 2026: 216Q2 2026

Total Exit/New Position Q1 2025 → Q2 2025

InstitutionsTotal Value
New Positions24$45.4M
Exits31$53.9M

All 13F filers, Q1 2025 → Q2 2025: 3,984,524 shares bought and 3,069,111 shares sold, net +915,413 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 151 holders

FMR LLC 0.01% Add +0.7% 3,245,710 $171.9M
Atlas Venture Life Science Advisors, LLC 19.07% No change 2,384,456 $126.3M
BlackRock, Inc. 0.00% Reduce -2.4% 2,044,827 $108.3M
Frazier Life Sciences Management, L.P. 3.51% Reduce -5.7% 1,654,834 $87.6M
Ra Capital Management, L.P. 1.41% No change 1,577,106 $83.5M
Janus Henderson Group PLC 0.04% Add +9.2% 1,553,961 $82.3M
T. Rowe Price Associates Inc. 0.01% Add +11.6% 1,515,625 $80.3M
Wellington Management Group LLP 0.01% Reduce -38.9% 1,432,090 $75.8M
Orbimed Advisors LLC 1.88% No change 1,415,020 $74.9M
Vanguard Group Inc. 0.00% Add +7.0% 1,396,736 $74.0M
Paradigm Biocapital Advisors LP 2.74% No change 1,210,971 $64.1M
Siren, L.L.C. 3.01% Add +2.6% 1,099,401 $58.2M
State Street Corp. 0.00% Add +1.2% 929,768 $49.2M
Deerfield Management Company, L.P. 0.99% Add +17.5% 919,403 $48.7M
Woodline Partners LP 0.24% Add +72.6% 866,955 $45.9M
JPMorgan Chase & Co. 0.00% Add +11.1% 843,616 $44.7M
Logos Global Management LP 4.95% Add +77.5% 700,000 $37.1M
Geode Capital Management, LLC 0.00% Add +4.7% 598,589 $31.7M
Bain Capital Life Sciences Investors, LLC 3.87% Reduce -40.7% 583,500 $30.9M
TCG Crossover Management, LLC 2.81% No change 465,257 $24.6M
Adage Capital Partners Gp, L.L.C. 0.04% Add +50.0% 450,000 $23.8M
Armistice Capital, LLC 0.88% No change 436,000 $23.1M
Saturn V Capital Management LP 8.50% Reduce -23.6% 396,115 $21.0M
Baker Bros. Advisors LP 0.17% Add +337.4% 337,050 $17.9M
Eventide Asset Management, LLC 0.29% Add +69.4% 308,030 $16.3M
First Turn Management, LLC 2.96% New 299,464 $15.9M
Foresite Capital Management V, LLC 19.62% No change 299,069 $15.8M
Nantahala Capital Management, LLC 1.08% Add +94.0% 287,800 $15.2M
Sio Capital Management, LLC 6.05% Add +287.4% 284,787 $15.1M
Checkpoint Capital L.P. 6.54% Add +8.9% 265,000 $14.0M
Goldman Sachs Group Inc. 0.00% Add +72.7% 225,856 $12.0M
Northern Trust Corp. 0.00% Add +4.9% 219,095 $11.6M
Charles Schwab Investment Management Inc. 0.00% Add +4.9% 204,241 $10.8M
Victory Capital Management Inc. 0.01% Add +2.1% 197,824 $10.5M
Dimensional Fund Advisors LP 0.00% Add +38.4% 192,856 $10.2M
Opaleye Management Inc. 2.04% Add +119.3% 186,418 $9.9M
Bank of America Corp. 0.00% Add +213.8% 168,822 $8.9M
Palo Alto Investors LP 1.64% New 145,691 $7.7M
UBS Group AG 0.00% Add +100.4% 145,549 $7.7M
Ensign Peak Advisors, Inc 0.01% Add +95.2% 141,545 $7.5M
Vestal Point Capital, LP 0.39% New 140,000 $7.4M
Blue Owl Capital Holdings LP 2.10% Reduce -12.8% 122,260 $6.5M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% Add +25.9% 121,584 $6.4M
Ameriprise Financial Inc. 0.00% Add +79.0% 121,520 $6.4M
Morgan Stanley 0.00% Reduce -35.0% 110,679 $5.9M
Renaissance Technologies 0.01% Reduce -49.6% 96,420 $5.1M
Zimmer Partners, LP 0.11% Add +110.2% 90,163 $4.8M
Barclays PLC 0.00% Add +89.4% 86,558 $4.6M
Raymond James Financial Inc. 0.00% Add +3.9% 86,487 $4.6M
Schroder Investment Management Group 0.00% Reduce -5.5% 82,451 $4.5M
Susquehanna International Group, LLP 0.01% Add +7.1% 75,997 $4.0M
Patient Square Capital LP 1.41% Reduce -10.8% 74,000 $3.9M
Bank of New York Mellon Corp 0.00% Add +12.6% 71,502 $3.8M
Exome Asset Management LLC 2.68% Reduce -0.5% 61,356 $3.2M
ExodusPoint Capital Management, LP 0.04% Add +327.2% 57,945 $3.1M
Nicholas Investment Partners, LP 0.29% New 54,445 $2.9M
TD Asset Management Inc 0.00% Add +25.0% 53,048 $2.8M
Manufacturers Life Insurance Company, The 0.00% Add +27.7% 51,836 $2.7M
Nuveen, LLC 0.00% Reduce -55.4% 50,270 $2.7M
Swiss National Bank 0.00% Add +19.5% 42,900 $2.3M
Rhumbline Advisers 0.00% Add +11.2% 35,755 $1.9M
Aberdeen Group plc 0.00% New 32,061 $1.7M
Rafferty Asset Management, LLC 0.01% Reduce -7.5% 31,489 $1.7M
PFM Health Sciences, LP 0.14% New 30,799 $1.6M
Catalio Capital Management, LP 0.34% New 30,661 $1.6M
Bollard Group LLC 0.04% New 30,635 $1.6M
PNC Financial Services Group, Inc. 0.00% Add +6.1% 25,140 $1.3M
Atle Fund Management AB 0.56% New 24,652 $1.3M
Alliancebernstein L.P. 0.00% Add +14.6% 24,140 $1.3M
Legal & General Group Plc 0.00% Add +18.0% 24,097 $1.3M
Royal Bank of Canada 0.00% Add +1786.4% 22,599 $1.2M
Wells Fargo & Company 0.00% Reduce -1.6% 22,461 $1.2M
Millennium Management 0.00% Reduce -80.1% 21,593 $1.1M
California State Teachers Retirement System 0.00% Add +0.5% 20,250 $1.1M
Voloridge Investment Management, LLC 0.00% New 19,726 $1.0M
Alps Advisors Inc. 0.01% Reduce -26.9% 18,626 $986K
Prelude Capital Management, LLC 0.09% Reduce -0.2% 18,156 $962K
New York State Common Retirement Fund 0.00% Add +168.5% 16,852 $892K
Invesco Ltd. 0.00% Add +21.6% 16,817 $891K
Deutsche Bank AG 0.00% Add +13.7% 16,717 $885K
Citigroup Inc. 0.00% Reduce -62.5% 16,109 $853K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Reduce -0.6% 15,041 $799K
MetLife Investment Management, LLC 0.00% Add +10.4% 14,854 $787K
Harvest Investment Services, LLC 0.17% Reduce -6.9% 14,316 $758K
Walleye Capital LLC 0.01% Reduce -36.3% 14,064 $745K
AQR Capital Management 0.00% New 13,649 $723K
State of Wisconsin Investment Board 0.00% Add +7.6% 12,889 $683K
Teachers Retirement System of the State of Kentucky 0.01% Reduce -12.2% 12,851 $681K
OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.02% Reduce -9.6% 12,317 $652K
Intech Investment Management LLC 0.01% Add +11.6% 12,222 $647K
Bank of Montreal 0.00% Add +87.8% 10,988 $582K
Lion Point Capital, LP 3.81% No change 10,600 $561K
First Trust Advisors LP 0.00% New 10,246 $543K
Y-Intercept (Hong Kong) Ltd 0.01% New 9,382 $497K
State Board of Administration of Florida Retirement System 0.00% Add +125.4% 9,129 $483K
Universal- Beteiligungs- und Servicegesellschaft mbH 0.00% Add +15.4% 7,376 $391K
Sofinnova Investments, Inc. 0.03% Reduce -2.3% 7,312 $387K
Legato Capital Management LLC 0.05% New 7,228 $383K
China Universal Asset Management Co., Ltd. 0.03% Add +0.3% 6,956 $368K
HighVista Strategies LLC 0.13% Add +4.3% 6,733 $357K
Profund Advisors LLC 0.01% Reduce -6.2% 6,714 $356K
Voya Investment Management LLC 0.00% Add +12.5% 6,695 $355K
Arizona State Retirement System 0.00% Add +22.9% 6,534 $346K
ProShare Advisors LLC 0.00% Reduce -2.4% 6,345 $336K
Teacher Retirement System of Texas 0.00% Add +21.2% 6,017 $319K
Police & Firemen's Retirement System of New Jersey 0.00% Add +12.3% 5,490 $291K
BNP Paribas Financial Markets 0.00% Reduce -54.3% 4,703 $249K
KLP Kapitalforvaltning As 0.00% Add +24.3% 4,600 $244K
DNB Asset Management AS 0.00% New 4,583 $243K
Fiduciary Trust Co 0.00% No change 4,051 $215K
Tower Research Capital LLC (TRC) 0.01% Add +383.0% 3,975 $211K
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% Reduce -0.9% 3,047 $161K
Ameritas Investment Partners, Inc. 0.00% Add +8.9% 2,515 $133K
Meeder Asset Management Inc. 0.01% New 2,244 $119K
STRS Ohio 0.00% Reduce -68.6% 2,200 $117K
Virtus Investment Advisers, LLC 0.03% Reduce -30.2% 1,784 $94K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +15.6% 1,338 $71K
US Bancorp \de 0.00% Reduce -2.0% 1,179 $62K
Avanza Fonder AB 0.00% New 1,083 $57K
Cwm, LLC 0.00% Add +213.5% 1,044 $55K
Amalgamated Bank 0.00% No change 787 $42K
GF Fund Management Co. LTD. 0.00% No change 762 $40K
Public Employees Retirement Association of Colorado 0.00% No change 730 $39K
Steward Partners Investment Advisory, LLC 0.00% Add +1.5% 533 $28K
AlphaQuest LLC 0.00% No change 327 $17K
iA Global Asset Management Inc. 0.00% New 322 $17K
Nisa Investment Advisors, LLC 0.00% Add +250.6% 284 $15K
Osaic Holdings, Inc. 0.00% New 270 $14K
GAMMA Investing LLC 0.00% Reduce -4.0% 240 $13K
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.00% New 202 $11K
Simplex Trading, LLC 0.00% Reduce -89.2% 199 $10K
Clearstead Advisors, LLC 0.00% Add +221.7% 148 $8K
Daiwa Securities Group Inc. 0.00% No change 113 $6K
Larson Financial Group LLC 0.00% New 109 $6K
EverSource Wealth Advisors, LLC 0.00% Add +620.0% 72 $4K
Sterling Capital Management LLC 0.00% Reduce -83.0% 60 $3K
Rothschild Investment LLC 0.00% No change 45 $2K
Comerica Bank 0.00% Add +47.1% 25 $1K
Parkside Financial Bank & Trust 0.00% New 20 $1K
Versant Capital Management, Inc 0.00% New 19 $1K
Bessemer Group Inc. 0.00% No change 12 $1K
Russell Investments Group, Ltd. 0.00% Add +60.0% 16 $847
Assetmark, Inc. 0.00% No change 12 $636
J.Safra Asset Management Corp 0.00% No change 6 $318
SBI Securities Co., Ltd. 0.00% No change 6 $318
Essential Partners LLC 0.00% — 4 $212
Allworth Financial LP 0.00% New 4 $212
Caitong International Asset Management Co., Ltd 0.00% Reduce -99.7% 3 $159
Global Retirement Partners, LLC 0.00% — 3 $159
True Wealth Design, LLC 0.00% Reduce -85.7% 1 $53
Covestor Ltd 0.00% No change 2 $0

"% of holder's portfolio" is IRON's weight in each manager's 13F, not the share of Disc Medicine Inc. the manager owns.