Disc MedicineIRON
13F holders, Q3 2025 (September 30)At the end of Q3 2025, 168 institutions reported holding Disc Medicine Inc. (IRON) in their 13F filings, up 17 from Q2 2025. 25 opened new positions and 9 sold out. The largest holders were FMR LLC ($326.1M), Atlas Venture Life Science Advisors, LLC ($141.6M) and BlackRock, Inc. ($133.4M). 5 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Steve Cohen (0.0% of Point72 Asset Management's portfolio).
- Company
- Disc Medicine Inc.
- CUSIP
- 254604101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 25 | $69.7M |
| Exits | 9 | $39.1M |
All 13F filers, Q2 2025 → Q3 2025: 4,727,091 shares bought and 4,576,243 shares sold, net +150,848 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 168 holders
| FMR LLC | 0.02% | Add +52.0% | 4,935,159 | $326.1M |
| Atlas Venture Life Science Advisors, LLC | 18.81% | Reduce -10.1% | 2,142,617 | $141.6M |
| BlackRock, Inc. | 0.00% | Reduce -1.3% | 2,019,283 | $133.4M |
| Ra Capital Management, L.P. | 1.28% | No change | 1,577,106 | $104.2M |
| Vanguard Group Inc. | 0.00% | Add +3.7% | 1,448,059 | $95.7M |
| Frazier Life Sciences Management, L.P. | 2.86% | Reduce -13.1% | 1,438,534 | $95.1M |
| Orbimed Advisors LLC | 2.24% | No change | 1,415,020 | $93.5M |
| Wellington Management Group LLP | 0.02% | Reduce -1.5% | 1,410,077 | $93.2M |
| T. Rowe Price Associates Inc. | 0.01% | Reduce -12.5% | 1,326,429 | $87.7M |
| State Street Corp. | 0.00% | Add +12.5% | 1,045,597 | $69.1M |
| Deerfield Management Company, L.P. | 1.01% | No change | 919,403 | $60.8M |
| Siren, L.L.C. | 2.36% | Reduce -16.9% | 913,401 | $60.4M |
| Woodline Partners LP | 0.27% | No change | 866,955 | $57.3M |
| JPMorgan Chase & Co. | 0.00% | Reduce -10.8% | 752,879 | $49.8M |
| Geode Capital Management, LLC | 0.00% | Add +4.9% | 628,151 | $41.5M |
| Goldman Sachs Group Inc. | 0.01% | Add +134.3% | 529,081 | $35.0M |
| Vestal Point Capital, LP | 1.50% | Add +257.1% | 500,000 | $33.0M |
| TCG Crossover Management, LLC | 1.51% | No change | 465,257 | $30.7M |
| Logos Global Management LP | 2.94% | Reduce -35.7% | 450,000 | $29.7M |
| Adage Capital Partners Gp, L.L.C. | 0.05% | No change | 450,000 | $29.7M |
| Armistice Capital, LLC | 0.91% | No change | 436,000 | $28.8M |
| Checkpoint Capital L.P. | 9.52% | Add +62.3% | 430,000 | $28.4M |
| First Turn Management, LLC | 3.95% | Add +32.8% | 397,693 | $26.3M |
| Janus Henderson Group PLC | 0.01% | Reduce -76.7% | 361,704 | $23.9M |
| Saturn V Capital Management LP | 4.94% | Reduce -13.9% | 340,897 | $22.5M |
| Balyasny Asset Management L.P. | 0.05% | New | 338,101 | $22.3M |
| Baker Bros. Advisors LP | 0.16% | No change | 337,050 | $22.3M |
| Eventide Asset Management, LLC | 0.33% | Add +0.0% | 308,043 | $20.4M |
| Foresite Capital Management V, LLC | 18.17% | No change | 299,069 | $19.8M |
| Nantahala Capital Management, LLC | 1.18% | No change | 287,800 | $19.0M |
| Sio Capital Management, LLC | 4.76% | No change | 284,787 | $18.8M |
| Paradigm Biocapital Advisors LP | 0.48% | Reduce -79.5% | 247,716 | $16.4M |
| First Light Asset Management, LLC | 1.44% | New | 231,186 | $15.3M |
| Dimensional Fund Advisors LP | 0.00% | Add +19.5% | 230,423 | $15.2M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +11.0% | 226,655 | $15.0M |
| Palo Alto Investors LP | 2.74% | Add +54.0% | 224,300 | $14.8M |
| Northern Trust Corp. | 0.00% | Add +0.2% | 219,489 | $14.5M |
| Catalio Capital Management, LP | 2.65% | Add +606.2% | 216,527 | $14.3M |
| Opaleye Management Inc. | 1.82% | Add +4.0% | 193,773 | $12.8M |
| TimesSquare Capital Management, LLC | 0.17% | New | 182,170 | $12.0M |
| Ensign Peak Advisors, Inc | 0.02% | Add +25.1% | 177,050 | $11.7M |
| UBS Group AG | 0.00% | Add +17.9% | 171,623 | $11.3M |
| Bank of America Corp. | 0.00% | Reduce -4.5% | 161,184 | $10.7M |
| Millennium Management | 0.01% | Add +645.6% | 161,000 | $10.6M |
| Victory Capital Management Inc. | 0.01% | Reduce -24.2% | 149,864 | $9.9M |
| Raymond James Financial Inc. | 0.00% | Add +63.6% | 141,479 | $9.3M |
| Barclays PLC | 0.00% | Add +23.9% | 107,203 | $7.1M |
| Blue Owl Capital Holdings LP | 2.11% | Reduce -16.4% | 102,260 | $6.8M |
| Hudson Bay Capital Management LP | 0.05% | New | 102,185 | $6.8M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -24.8% | 91,380 | $6.0M |
| Zimmer Partners, LP | 0.15% | No change | 90,163 | $6.0M |
| Nicholas Investment Partners, LP | 0.51% | Add +61.6% | 88,003 | $5.8M |
| Ameriprise Financial Inc. | 0.00% | Reduce -38.8% | 74,350 | $4.9M |
| Patient Square Capital LP | 1.31% | No change | 74,000 | $4.9M |
| Schroder Investment Management Group | 0.00% | Reduce -18.5% | 67,196 | $4.4M |
| iA Global Asset Management Inc. | 0.06% | Add +20245.3% | 65,512 | $4.3M |
| Bank of New York Mellon Corp | 0.00% | Reduce -9.4% | 64,800 | $4.3M |
| Exome Asset Management LLC | 2.68% | No change | 61,356 | $4.1M |
| TD Asset Management Inc | 0.00% | Add +11.7% | 59,248 | $3.9M |
| Morgan Stanley | 0.00% | Reduce -49.3% | 56,075 | $3.7M |
| Citadel Advisors | 0.00% | New | 50,394 | $3.3M |
| Nuveen, LLC | 0.00% | Reduce -5.1% | 47,694 | $3.2M |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -8.2% | 47,577 | $3.1M |
| Swiss National Bank | 0.00% | Add +1.6% | 43,600 | $2.9M |
| Y-Intercept (Hong Kong) Ltd | 0.07% | Add +361.4% | 43,287 | $2.9M |
| BNP Paribas Financial Markets | 0.00% | Add +699.7% | 37,610 | $2.5M |
| Rafferty Asset Management, LLC | 0.01% | Add +18.5% | 37,302 | $2.5M |
| Rhumbline Advisers | 0.00% | Reduce -3.5% | 34,490 | $2.3M |
| Susquehanna International Group, LLP | 0.00% | Reduce -57.1% | 32,617 | $2.2M |
| PFM Health Sciences, LP | 0.19% | Add +5.7% | 32,539 | $2.2M |
| Aberdeen Group plc | 0.00% | No change | 32,061 | $2.1M |
| American Century Companies Inc. | 0.00% | New | 27,938 | $1.8M |
| Wells Fargo & Company | 0.00% | Add +20.4% | 27,055 | $1.8M |
| Legal & General Group Plc | 0.00% | Add +4.4% | 25,147 | $1.7M |
| PNC Financial Services Group, Inc. | 0.00% | Add +0.0% | 25,146 | $1.7M |
| Alliancebernstein L.P. | 0.00% | Add +1.7% | 24,540 | $1.6M |
| California State Teachers Retirement System | 0.00% | Add +9.1% | 22,093 | $1.5M |
| New York State Common Retirement Fund | 0.00% | Add +27.5% | 21,490 | $1.4M |
| Invesco Ltd. | 0.00% | Add +27.5% | 21,443 | $1.4M |
| Jane Street Group, LLC | 0.00% | New | 21,274 | $1.4M |
| Deutsche Bank AG | 0.00% | Add +13.0% | 18,886 | $1.2M |
| Prelude Capital Management, LLC | 0.09% | No change | 18,156 | $1.2M |
| Bank of Montreal | 0.00% | Add +61.9% | 17,785 | $1.2M |
| Alps Advisors Inc. | 0.01% | Reduce -9.8% | 16,792 | $1.1M |
| Royal Bank of Canada | 0.00% | Reduce -26.1% | 16,696 | $1.1M |
| Walleye Capital LLC | 0.01% | Add +4.2% | 14,649 | $968K |
| Marshall Wace, LLP | 0.00% | New | 14,001 | $925K |
| AQR Capital Management | 0.00% | Add +2.4% | 13,978 | $924K |
| MetLife Investment Management, LLC | 0.00% | Reduce -6.3% | 13,922 | $920K |
| Fred Alger Management, LLC | 0.00% | New | 13,726 | $907K |
| Sofinnova Investments, Inc. | 0.05% | Add +85.3% | 13,553 | $896K |
| Teachers Retirement System of the State of Kentucky | 0.01% | No change | 12,851 | $849K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -15.9% | 12,646 | $834K |
| State of Wisconsin Investment Board | 0.00% | Reduce -4.0% | 12,373 | $818K |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | Add +55.1% | 11,438 | $756K |
| Legato Capital Management LLC | 0.08% | Add +56.2% | 11,287 | $746K |
| Lion Point Capital, LP | 3.98% | No change | 10,600 | $700K |
| Assenagon Asset Management S.A. | 0.00% | New | 10,433 | $689K |
| Point72 Asset Management | 0.00% | New | 9,226 | $610K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 9,129 | $603K |
| Kennedy Capital Management LLC | 0.01% | New | 9,028 | $597K |
| Cubist Systematic Strategies, LLC | 0.01% | New | 8,714 | $576K |
| Profund Advisors LLC | 0.02% | Add +20.9% | 8,118 | $536K |
| SG Americas Securities, LLC | 0.00% | New | 8,064 | $533K |
| Intech Investment Management LLC | 0.00% | Reduce -34.5% | 8,006 | $529K |
| China Universal Asset Management Co., Ltd. | 0.04% | Add +2.0% | 7,094 | $469K |
| Renaissance Technologies | 0.00% | Reduce -93.0% | 6,800 | $449K |
| Arizona State Retirement System | 0.00% | Add +1.8% | 6,654 | $440K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +18.4% | 6,501 | $430K |
| Verition Fund Management LLC | 0.00% | New | 6,133 | $405K |
| DNB Asset Management AS | 0.00% | Add +20.5% | 5,522 | $365K |
| Teacher Retirement System of Texas | 0.00% | Reduce -8.8% | 5,487 | $363K |
| Squarepoint Ops LLC | 0.00% | New | 5,377 | $355K |
| Campbell & CO Investment Adviser LLC | 0.03% | New | 5,290 | $350K |
| ProShare Advisors LLC | 0.00% | Reduce -18.2% | 5,188 | $343K |
| Atle Fund Management AB | 1.19% | Add +85.3% | 45,690 | $321K |
| KLP Kapitalforvaltning As | 0.00% | No change | 4,600 | $304K |
| Voya Investment Management LLC | 0.00% | Reduce -36.3% | 4,266 | $282K |
| Fiduciary Trust Co | 0.00% | No change | 4,051 | $268K |
| Citigroup Inc. | 0.00% | Reduce -74.9% | 4,045 | $267K |
| Bryce Point Capital, LLC | 0.32% | New | 3,912 | $259K |
| Susquehanna Portfolio Strategies, LLC | 0.00% | New | 3,733 | $247K |
| Pictet Asset Management Holding SA | 0.00% | New | 3,563 | $235K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Reduce -1.9% | 2,988 | $197K |
| Russell Investments Group, Ltd. | 0.00% | Add +15137.5% | 2,438 | $161K |
| STRS Ohio | 0.00% | No change | 2,200 | $145K |
| Virtus Investment Advisers, LLC | 0.04% | Add +21.0% | 2,158 | $143K |
| Ameritas Investment Partners, Inc. | 0.00% | Reduce -23.2% | 1,931 | $128K |
| Avanza Fonder AB | 0.00% | Add +54.0% | 1,668 | $110K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +0.5% | 1,344 | $89K |
| US Bancorp \de | 0.00% | Reduce -0.3% | 1,176 | $78K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -72.2% | 1,105 | $73K |
| Cwm, LLC | 0.00% | Reduce -1.6% | 1,027 | $68K |
| Simplex Trading, LLC | 0.00% | Add +302.0% | 800 | $52K |
| Amalgamated Bank | 0.00% | No change | 787 | $52K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -1.8% | 748 | $49K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 730 | $48K |
| Aster Capital Management (DIFC) Ltd | 0.02% | New | 576 | $38K |
| Steward Partners Investment Advisory, LLC | 0.00% | No change | 533 | $35K |
| AlphaQuest LLC | 0.00% | No change | 327 | $22K |
| Nisa Investment Advisors, LLC | 0.00% | Add +3.2% | 293 | $19K |
| GAMMA Investing LLC | 0.00% | Add +15.0% | 276 | $18K |
| Osaic Holdings, Inc. | 0.00% | No change | 270 | $18K |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | Add +5.5% | 213 | $14K |
| Arax Advisory Partners | 0.00% | New | 206 | $14K |
| Optiver Holding B.V. | 0.00% | New | 194 | $13K |
| Larson Financial Group LLC | 0.00% | Reduce -0.9% | 108 | $7K |
| Daiwa Securities Group Inc. | 0.00% | No change | 113 | $7K |
| Clearstead Advisors, LLC | 0.00% | Reduce -31.1% | 102 | $7K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +4.2% | 75 | $5K |
| Caitong International Asset Management Co., Ltd | 0.00% | Add +1900.0% | 60 | $4K |
| Sterling Capital Management LLC | 0.00% | Reduce -6.7% | 56 | $4K |
| Comerica Bank | 0.00% | Add +76.0% | 44 | $3K |
| Rothschild Investment LLC | 0.00% | Reduce -11.1% | 40 | $3K |
| Parkside Financial Bank & Trust | 0.00% | No change | 20 | $1K |
| Versant Capital Management, Inc | 0.00% | No change | 19 | $1K |
| Assetmark, Inc. | 0.00% | No change | 12 | $793 |
| Bare Financial Services, Inc | 0.00% | New | 9 | $595 |
| Farther Finance Advisors, LLC | 0.00% | New | 7 | $463 |
| Allworth Financial LP | 0.00% | Add +50.0% | 6 | $397 |
| J.Safra Asset Management Corp | 0.00% | No change | 6 | $396 |
| Global Retirement Partners, LLC | 0.00% | Add +100.0% | 6 | $396 |
| SBI Securities Co., Ltd. | 0.00% | No change | 6 | $396 |
| Essential Partners LLC | 0.00% | No change | 4 | $264 |
| IFP Advisors, Inc | 0.00% | Add +0.0% | 3 | $198 |
| True Wealth Design, LLC | 0.00% | No change | 1 | $67 |
| Bessemer Group Inc. | 0.00% | Reduce -83.3% | 2 | $0 |
| Covestor Ltd | 0.00% | No change | 2 | $0 |
"% of holder's portfolio" is IRON's weight in each manager's 13F, not the share of Disc Medicine Inc. the manager owns.