Ironwood PharmaceuticalsIRWD
13F holders, Q4 2025 (December 31)199holders +33
52new positions
18sold out
6famous investors
$3.36avg. 13F price*
At the end of Q4 2025, 199 institutions reported holding Ironwood Pharmaceuticals Inc. (IRWD) in their 13F filings, up 33 from Q3 2025. 52 opened new positions and 18 sold out. The largest holders were Armistice Capital, LLC ($54.0M), Vanguard Group Inc. ($53.8M) and Sarissa Capital Management LP ($53.6M). 6 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Cliff Asness (0.0% of AQR Capital Management's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Ironwood Pharmaceuticals Inc.
- CUSIP
- 46333X108
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 52 | $28.4M |
| Exits | 18 | $9.3M |
All 13F filers, Q3 2025 → Q4 2025: 18,685,729 shares bought and 12,706,309 shares sold, net +5,979,420 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 199 holders
| Armistice Capital, LLC | 1.32% | Reduce -0.8% | 16,025,000 | $54.0M |
| Vanguard Group Inc. | 0.00% | Reduce -0.7% | 15,958,196 | $53.8M |
| Sarissa Capital Management LP | 24.07% | No change | 15,919,435 | $53.6M |
| BlackRock, Inc. | 0.00% | Add +6.0% | 12,784,806 | $43.1M |
| Bank of America Corp. | 0.00% | Reduce -1.5% | 11,521,660 | $38.8M |
| Renaissance Technologies | 0.04% | Reduce -1.8% | 8,204,973 | $27.7M |
| Acadian Asset Management LLC | 0.04% | Reduce -0.7% | 6,457,817 | $21.7M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +1.2% | 4,975,939 | $16.8M |
| AQR Capital Management | 0.01% | Reduce -12.2% | 4,723,531 | $15.9M |
| Marshall Wace, LLP | 0.01% | Add +40.7% | 4,424,002 | $14.9M |
| State Street Corp. | 0.00% | Add +39.8% | 4,411,222 | $14.9M |
| Geode Capital Management, LLC | 0.00% | Add +0.2% | 3,623,534 | $12.2M |
| Federated Hermes, Inc. | 0.02% | Add +53.8% | 3,318,137 | $11.2M |
| Two Sigma Advisers, LP | 0.02% | Reduce -5.3% | 3,140,100 | $10.6M |
| Two Sigma Investments, LP | 0.02% | Add +12.6% | 2,853,205 | $9.6M |
| Jane Street Group, LLC | 0.01% | Add +21.5% | 2,819,562 | $9.5M |
| Jacobs Levy Equity Management, Inc. | 0.04% | Add +43.7% | 2,759,667 | $9.3M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.02% | Reduce -7.9% | 1,990,927 | $6.7M |
| Qube Research & Technologies Ltd | 0.01% | Reduce -40.1% | 1,681,229 | $5.7M |
| Goldman Sachs Group Inc. | 0.00% | Add +17.6% | 1,275,315 | $4.3M |
| Northern Trust Corp. | 0.00% | Reduce -8.0% | 1,233,685 | $4.2M |
| Hillsdale Investment Management Inc. | 0.11% | New | 1,156,378 | $3.9M |
| Deutsche Bank AG | 0.00% | Reduce -27.3% | 1,109,924 | $3.7M |
| Lazard Asset Management LLC | 0.01% | New | 1,000,445 | $3.4M |
| Raymond James Financial Inc. | 0.00% | Add +5681.1% | 869,826 | $2.9M |
| Morgan Stanley | 0.00% | Add +55.0% | 739,685 | $2.5M |
| FMR LLC | 0.00% | Add +22.6% | 686,737 | $2.3M |
| Diadema Partners LP | 1.37% | New | 683,611 | $2.3M |
| Sei Investments Co. | 0.00% | Reduce -1.4% | 673,862 | $2.3M |
| Exome Asset Management LLC | 1.08% | New | 648,532 | $2.2M |
| Amundi | 0.00% | New | 642,830 | $2.2M |
| Ieq Capital, LLC | 0.01% | Reduce -4.3% | 633,260 | $2.1M |
| Gsa Capital Partners LLP | 0.17% | Add +84.7% | 571,613 | $1.9M |
| Millennium Management | 0.00% | Add +124.2% | 560,713 | $1.9M |
| Walleye Capital LLC | 0.01% | New | 527,936 | $1.8M |
| UBS Group AG | 0.00% | Reduce -37.1% | 510,543 | $1.7M |
| Bank of New York Mellon Corp | 0.00% | Add +1.4% | 510,207 | $1.7M |
| Wellington Management Group LLP | 0.00% | New | 503,942 | $1.7M |
| Bridgeway Capital Management, LLC | 0.04% | Add +230.7% | 495,993 | $1.7M |
| Invesco Ltd. | 0.00% | Add +22.6% | 449,219 | $1.5M |
| Susquehanna International Group, LLP | 0.00% | Add +363.3% | 448,799 | $1.5M |
| Range Financial Group LLC | 0.50% | New | 426,095 | $1.4M |
| Arrowstreet Capital, Limited Partnership | 0.00% | New | 412,061 | $1.4M |
| Barclays PLC | 0.00% | Add +32.1% | 392,904 | $1.3M |
| Franklin Resources Inc. | 0.00% | Add +1558.3% | 385,583 | $1.3M |
| Robeco Institutional Asset Management B.V. | 0.00% | No change | 342,998 | $1.2M |
| Cerity Partners LLC | 0.00% | Reduce -0.2% | 338,512 | $1.1M |
| Dimensional Fund Advisors LP | 0.00% | Add +266.1% | 330,836 | $1.1M |
| O'shaughnessy Asset Management, LLC | 0.01% | New | 290,278 | $978K |
| Los Angeles Capital Management LLC | 0.00% | Reduce -43.9% | 634,331 | $951K |
| Russell Investments Group, Ltd. | 0.00% | Reduce -18.7% | 265,357 | $894K |
| Cwm, LLC | 0.00% | Add +0.1% | 232,984 | $785K |
| Citadel Advisors | 0.00% | Reduce -65.2% | 223,969 | $755K |
| OMERS ADMINISTRATION Corp | 0.01% | No change | 215,110 | $725K |
| JPMorgan Chase & Co. | 0.00% | Add +91.3% | 214,607 | $723K |
| Rhumbline Advisers | 0.00% | Reduce -10.4% | 199,908 | $674K |
| Alliancebernstein L.P. | 0.00% | No change | 199,520 | $672K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Add +0.7% | 155,523 | $665K |
| Hennion & Walsh Asset Management, Inc. | 0.02% | Add +15.7% | 196,032 | $661K |
| Canada Pension Plan Investment Board | 0.00% | New | 188,000 | $634K |
| Persistent Asset Partners Ltd | 0.29% | New | 182,046 | $613K |
| State of Wisconsin Investment Board | 0.00% | New | 180,040 | $607K |
| Wells Fargo & Company | 0.00% | Add +74.4% | 176,582 | $595K |
| KLP Kapitalforvaltning As | 0.00% | No change | 174,200 | $587K |
| WINTON GROUP Ltd | 0.02% | New | 164,335 | $554K |
| Creative Planning | 0.00% | Add +79.8% | 162,075 | $546K |
| State of Wyoming | 0.06% | Reduce -56.6% | 157,325 | $530K |
| Prudential Financial Inc. | 0.00% | Add +182.6% | 141,129 | $476K |
| Nuveen, LLC | 0.00% | New | 139,487 | $470K |
| Prelude Capital Management, LLC | 0.03% | New | 136,507 | $460K |
| Ameriprise Financial Inc. | 0.00% | No change | 119,969 | $404K |
| Quantinno Capital Management LP | 0.00% | New | 118,893 | $401K |
| D. E. Shaw & Co. | 0.00% | Reduce -68.5% | 117,446 | $396K |
| Mariner, LLC | 0.00% | Add +12.6% | 114,119 | $384K |
| Integrated Quantitative Investments LLC | 0.07% | New | 102,654 | $346K |
| Cercano Management LLC | 0.01% | No change | 101,378 | $342K |
| T. Rowe Price Associates Inc. | 0.00% | Add +23.9% | 99,363 | $335K |
| Squarepoint Ops LLC | 0.00% | Add +338.6% | 88,880 | $300K |
| Pallas Capital Advisors LLC | 0.01% | Add +0.5% | 87,975 | $296K |
| MetLife Investment Management, LLC | 0.00% | Add +50.9% | 87,521 | $295K |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | Reduce -36.7% | 79,013 | $266K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +7.0% | 78,103 | $263K |
| Mercer Global Advisors Inc. | 0.00% | Add +7.8% | 76,951 | $259K |
| STRS Ohio | 0.00% | No change | 76,600 | $258K |
| Exchange Traded Concepts, LLC | 0.00% | Reduce -60.9% | 76,554 | $258K |
| SmartHarvest Portfolios, LLC | 0.09% | — | 75,585 | $255K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Add +2.9% | 74,839 | $252K |
| Virtus Investment Advisers, LLC | 0.07% | New | 74,311 | $250K |
| Intech Investment Management LLC | 0.00% | Reduce -0.9% | 71,573 | $241K |
| Cibc World Market Inc. | 0.00% | New | 71,331 | $240K |
| Public Employees Retirement System of Ohio | 0.00% | Add +11.7% | 67,888 | $229K |
| Scotia Capital Inc. | 0.00% | New | 67,183 | $226K |
| EntryPoint Capital, LLC | 0.09% | New | 66,625 | $225K |
| Balyasny Asset Management L.P. | 0.00% | New | 65,156 | $220K |
| Rafferty Asset Management, LLC | 0.00% | New | 64,841 | $219K |
| Captrust Financial Advisors | 0.00% | Add +1.1% | 63,822 | $215K |
| Wedbush Securities Inc. | 0.01% | New | 63,733 | $215K |
| Optimist Retirement Group LLC | 0.09% | New | 59,912 | $202K |
| Focus Partners Advisor Solutions, LLC | 0.00% | Add +14.0% | 59,617 | $201K |
| Virtus Advisers, LLC | 0.09% | New | 58,000 | $195K |
"% of holder's portfolio" is IRWD's weight in each manager's 13F, not the share of Ironwood Pharmaceuticals Inc. the manager owns.