Ironwood PharmaceuticalsIRWD

13F holders, Q4 2025 (December 31)
199holders +33
52new positions
18sold out
6famous investors
$3.36avg. 13F price*

At the end of Q4 2025, 199 institutions reported holding Ironwood Pharmaceuticals Inc. (IRWD) in their 13F filings, up 33 from Q3 2025. 52 opened new positions and 18 sold out. The largest holders were Armistice Capital, LLC ($54.0M), Vanguard Group Inc. ($53.8M) and Sarissa Capital Management LP ($53.6M). 6 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Cliff Asness (0.0% of AQR Capital Management's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).

Company
Ironwood Pharmaceuticals Inc.
CUSIP
46333X108
Latest filing quarter
Q2 2026

History

Number of 13F holders

0100200300 Q1 2024: 261Q1 2024Q2 2024: 227Q2 2024Q3 2024: 221Q3 2024Q4 2024: 223Q4 2024Q1 2025: 200Q1 2025Q2 2025: 155Q2 2025Q3 2025: 166Q3 2025Q4 2025: 199Q4 2025Q1 2026: 227Q1 2026Q2 2026: 212Q2 2026

Total Exit/New Position Q3 2025 → Q4 2025

InstitutionsTotal Value
New Positions52$28.4M
Exits18$9.3M

All 13F filers, Q3 2025 → Q4 2025: 18,685,729 shares bought and 12,706,309 shares sold, net +5,979,420 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 199 holders

Armistice Capital, LLC 1.32% Reduce -0.8% 16,025,000 $54.0M
Vanguard Group Inc. 0.00% Reduce -0.7% 15,958,196 $53.8M
Sarissa Capital Management LP 24.07% No change 15,919,435 $53.6M
BlackRock, Inc. 0.00% Add +6.0% 12,784,806 $43.1M
Bank of America Corp. 0.00% Reduce -1.5% 11,521,660 $38.8M
Renaissance Technologies 0.04% Reduce -1.8% 8,204,973 $27.7M
Acadian Asset Management LLC 0.04% Reduce -0.7% 6,457,817 $21.7M
Charles Schwab Investment Management Inc. 0.00% Add +1.2% 4,975,939 $16.8M
AQR Capital Management 0.01% Reduce -12.2% 4,723,531 $15.9M
Marshall Wace, LLP 0.01% Add +40.7% 4,424,002 $14.9M
State Street Corp. 0.00% Add +39.8% 4,411,222 $14.9M
Geode Capital Management, LLC 0.00% Add +0.2% 3,623,534 $12.2M
Federated Hermes, Inc. 0.02% Add +53.8% 3,318,137 $11.2M
Two Sigma Advisers, LP 0.02% Reduce -5.3% 3,140,100 $10.6M
Two Sigma Investments, LP 0.02% Add +12.6% 2,853,205 $9.6M
Jane Street Group, LLC 0.01% Add +21.5% 2,819,562 $9.5M
Jacobs Levy Equity Management, Inc. 0.04% Add +43.7% 2,759,667 $9.3M
Connor, Clark & Lunn Investment Management Ltd. 0.02% Reduce -7.9% 1,990,927 $6.7M
Qube Research & Technologies Ltd 0.01% Reduce -40.1% 1,681,229 $5.7M
Goldman Sachs Group Inc. 0.00% Add +17.6% 1,275,315 $4.3M
Northern Trust Corp. 0.00% Reduce -8.0% 1,233,685 $4.2M
Hillsdale Investment Management Inc. 0.11% New 1,156,378 $3.9M
Deutsche Bank AG 0.00% Reduce -27.3% 1,109,924 $3.7M
Lazard Asset Management LLC 0.01% New 1,000,445 $3.4M
Raymond James Financial Inc. 0.00% Add +5681.1% 869,826 $2.9M
Morgan Stanley 0.00% Add +55.0% 739,685 $2.5M
FMR LLC 0.00% Add +22.6% 686,737 $2.3M
Diadema Partners LP 1.37% New 683,611 $2.3M
Sei Investments Co. 0.00% Reduce -1.4% 673,862 $2.3M
Exome Asset Management LLC 1.08% New 648,532 $2.2M
Amundi 0.00% New 642,830 $2.2M
Ieq Capital, LLC 0.01% Reduce -4.3% 633,260 $2.1M
Gsa Capital Partners LLP 0.17% Add +84.7% 571,613 $1.9M
Millennium Management 0.00% Add +124.2% 560,713 $1.9M
Walleye Capital LLC 0.01% New 527,936 $1.8M
UBS Group AG 0.00% Reduce -37.1% 510,543 $1.7M
Bank of New York Mellon Corp 0.00% Add +1.4% 510,207 $1.7M
Wellington Management Group LLP 0.00% New 503,942 $1.7M
Bridgeway Capital Management, LLC 0.04% Add +230.7% 495,993 $1.7M
Invesco Ltd. 0.00% Add +22.6% 449,219 $1.5M
Susquehanna International Group, LLP 0.00% Add +363.3% 448,799 $1.5M
Range Financial Group LLC 0.50% New 426,095 $1.4M
Arrowstreet Capital, Limited Partnership 0.00% New 412,061 $1.4M
Barclays PLC 0.00% Add +32.1% 392,904 $1.3M
Franklin Resources Inc. 0.00% Add +1558.3% 385,583 $1.3M
Robeco Institutional Asset Management B.V. 0.00% No change 342,998 $1.2M
Cerity Partners LLC 0.00% Reduce -0.2% 338,512 $1.1M
Dimensional Fund Advisors LP 0.00% Add +266.1% 330,836 $1.1M
O'shaughnessy Asset Management, LLC 0.01% New 290,278 $978K
Los Angeles Capital Management LLC 0.00% Reduce -43.9% 634,331 $951K
Russell Investments Group, Ltd. 0.00% Reduce -18.7% 265,357 $894K
Cwm, LLC 0.00% Add +0.1% 232,984 $785K
Citadel Advisors 0.00% Reduce -65.2% 223,969 $755K
OMERS ADMINISTRATION Corp 0.01% No change 215,110 $725K
JPMorgan Chase & Co. 0.00% Add +91.3% 214,607 $723K
Rhumbline Advisers 0.00% Reduce -10.4% 199,908 $674K
Alliancebernstein L.P. 0.00% No change 199,520 $672K
Wealth Enhancement Advisory Services, LLC 0.00% Add +0.7% 155,523 $665K
Hennion & Walsh Asset Management, Inc. 0.02% Add +15.7% 196,032 $661K
Canada Pension Plan Investment Board 0.00% New 188,000 $634K
Persistent Asset Partners Ltd 0.29% New 182,046 $613K
State of Wisconsin Investment Board 0.00% New 180,040 $607K
Wells Fargo & Company 0.00% Add +74.4% 176,582 $595K
KLP Kapitalforvaltning As 0.00% No change 174,200 $587K
WINTON GROUP Ltd 0.02% New 164,335 $554K
Creative Planning 0.00% Add +79.8% 162,075 $546K
State of Wyoming 0.06% Reduce -56.6% 157,325 $530K
Prudential Financial Inc. 0.00% Add +182.6% 141,129 $476K
Nuveen, LLC 0.00% New 139,487 $470K
Prelude Capital Management, LLC 0.03% New 136,507 $460K
Ameriprise Financial Inc. 0.00% No change 119,969 $404K
Quantinno Capital Management LP 0.00% New 118,893 $401K
D. E. Shaw & Co. 0.00% Reduce -68.5% 117,446 $396K
Mariner, LLC 0.00% Add +12.6% 114,119 $384K
Integrated Quantitative Investments LLC 0.07% New 102,654 $346K
Cercano Management LLC 0.01% No change 101,378 $342K
T. Rowe Price Associates Inc. 0.00% Add +23.9% 99,363 $335K
Squarepoint Ops LLC 0.00% Add +338.6% 88,880 $300K
Pallas Capital Advisors LLC 0.01% Add +0.5% 87,975 $296K
MetLife Investment Management, LLC 0.00% Add +50.9% 87,521 $295K
Universal- Beteiligungs- und Servicegesellschaft mbH 0.00% Reduce -36.7% 79,013 $266K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Add +7.0% 78,103 $263K
Mercer Global Advisors Inc. 0.00% Add +7.8% 76,951 $259K
STRS Ohio 0.00% No change 76,600 $258K
Exchange Traded Concepts, LLC 0.00% Reduce -60.9% 76,554 $258K
SmartHarvest Portfolios, LLC 0.09% — 75,585 $255K
Vanguard Personalized Indexing Management, LLC 0.00% Add +2.9% 74,839 $252K
Virtus Investment Advisers, LLC 0.07% New 74,311 $250K
Intech Investment Management LLC 0.00% Reduce -0.9% 71,573 $241K
Cibc World Market Inc. 0.00% New 71,331 $240K
Public Employees Retirement System of Ohio 0.00% Add +11.7% 67,888 $229K
Scotia Capital Inc. 0.00% New 67,183 $226K
EntryPoint Capital, LLC 0.09% New 66,625 $225K
Balyasny Asset Management L.P. 0.00% New 65,156 $220K
Rafferty Asset Management, LLC 0.00% New 64,841 $219K
Captrust Financial Advisors 0.00% Add +1.1% 63,822 $215K
Wedbush Securities Inc. 0.01% New 63,733 $215K
Optimist Retirement Group LLC 0.09% New 59,912 $202K
Focus Partners Advisor Solutions, LLC 0.00% Add +14.0% 59,617 $201K
Virtus Advisers, LLC 0.09% New 58,000 $195K
SG Americas Securities, LLC 0.00% Add +56.3% 57,747 $195K
Panagora Asset Management Inc. 0.00% Reduce -65.8% 54,408 $183K
Merit Financial Group, LLC 0.00% Add +1.0% 49,378 $166K
Polymer Capital Management (US) LLC 0.02% New 48,747 $164K
Man Group plc 0.00% New 47,659 $161K
Manufacturers Life Insurance Company, The 0.00% Reduce -11.8% 47,588 $160K
Krilogy Financial LLC 0.01% Add +0.1% 30,223 $157K
Police & Firemen's Retirement System of New Jersey 0.00% No change 44,115 $149K
Focus Partners Wealth 0.00% Reduce -1.5% 43,965 $148K
XTX Topco Ltd 0.00% Add +290.4% 43,904 $148K
New York State Common Retirement Fund 0.00% No change 41,869 $141K
Engineers Gate Manager LP 0.00% Reduce -62.1% 38,701 $130K
ProShare Advisors LLC 0.00% Add +9.6% 36,315 $122K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +474.7% 36,090 $122K
BNP Paribas Financial Markets 0.00% Reduce -5.5% 32,454 $109K
Jain Global LLC 0.00% New 30,009 $101K
Vise Technologies, Inc. 0.00% Add +0.2% 29,680 $100K
Voya Investment Management LLC 0.00% Reduce -2.1% 28,759 $97K
China Universal Asset Management Co., Ltd. 0.01% Reduce -6.9% 26,508 $89K
Profund Advisors LLC 0.00% New 26,483 $89K
Commonwealth Equity Services, LLC 0.00% New 26,478 $89K
GRIMES & Co WEALTH MANAGEMENT, LLC 0.00% Reduce -36.9% 25,887 $87K
HSBC Holdings PLC 0.00% New 23,436 $79K
Essential Partners LLC 0.02% Add +0.7% 22,081 $74K
OVERSEA-CHINESE BANKING Corp Ltd 0.00% No change 21,465 $72K
Harvest Investment Services, LLC 0.01% New 20,170 $68K
Victory Capital Management Inc. 0.00% Add +0.2% 18,042 $61K
Broderick Brian C 0.01% No change 18,000 $61K
NorthCrest Asset Manangement, LLC 0.00% Add +1.2% 13,157 $60K
Ariadne Wealth Management, LP 0.02% Reduce -0.1% 12,224 $56K
Legal & General Group Plc 0.00% Reduce -9.1% 16,690 $56K
Abel Hall, LLC 0.01% New 16,661 $56K
HighTower Advisors, LLC 0.00% Add +7.7% 16,150 $54K
Citigroup Inc. 0.00% Reduce -23.3% 15,501 $52K
Tower Research Capital LLC (TRC) 0.00% Add +59.1% 15,149 $51K
Neuberger Berman Group LLC 0.00% Add +45.0% 14,852 $50K
Evolve Private Wealth, LLC 0.00% — 14,809 $50K
Calamos Advisors LLC 0.00% New 14,520 $49K
Ameritas Investment Partners, Inc. 0.00% No change 13,773 $46K
EverSource Wealth Advisors, LLC 0.00% Reduce -6.1% 13,680 $46K
Farallon Capital Management, L.L.C. 0.00% No change 13,000 $44K
Diversified Trust Co. 0.00% No change 12,574 $42K
waypoint wealth counsel 0.02% Reduce -1.2% 12,503 $42K
Xponance LLC 0.00% Add +0.7% 12,419 $42K
MQS Management LLC 0.02% New 12,414 $42K
Coldstream Capital Management Inc. 0.00% Add +11.8% 12,300 $41K
Cetera Investment Advisers 0.00% No change 11,949 $40K
Integrated Wealth Concepts LLC 0.00% Reduce -40.7% 11,436 $39K
Mackenzie Financial Corp. 0.00% Add +10.4% 11,544 $38K
Evoke Wealth, LLC 0.00% Add +4.2% 11,287 $38K
Stonebrook Private Inc. 0.01% No change 10,985 $37K
Simplify Asset Management Inc. 0.00% New 10,946 $37K
Cibc World Markets Corp. 0.00% — 10,585 $36K
Kaufman Rossin Wealth, LLC 0.02% No change 10,516 $35K
DGS Capital Management, LLC 0.01% New 10,425 $35K
Jump Financial, LLC 0.00% New 10,062 $34K
Fisher Asset Management 0.00% No change 10,000 $34K
California State Teachers Retirement System 0.00% Reduce -4.0% 9,851 $33K
LSV Asset Management 0.00% New 9,048 $30K
EMC Capital Management 0.01% Reduce -15.0% 8,386 $28K
Harbor Capital Advisors, Inc. 0.00% Reduce -1.7% 7,902 $27K
NewEdge Advisors, LLC 0.00% New 5,793 $20K
Royal Bank of Canada 0.00% Add +250.0% 5,310 $18K
Amalgamated Bank 0.00% Add +7.5% 5,027 $17K
IFP Advisors, Inc 0.00% Add +0.2% 4,033 $14K
Osaic Holdings, Inc. 0.00% Add +1.4% 3,399 $11K
GF Fund Management Co. LTD. 0.00% Reduce -5.6% 3,196 $11K
Global Retirement Partners, LLC 0.00% New 2,713 $9K
GAMMA Investing LLC 0.00% New 2,462 $8K
True Wealth Design, LLC 0.00% No change 2,361 $8K
WealthCollab, LLC 0.00% No change 1,970 $7K
Sterling Capital Management LLC 0.00% Add +54.4% 1,916 $6K
Jones Financial Companies LLLP 0.00% New 1,683 $6K
Physician Wealth Advisors, Inc. 0.00% No change 1,669 $6K
Nisa Investment Advisors, LLC 0.00% No change 1,627 $5K
Allworth Financial LP 0.00% Add +18.6% 1,457 $5K
Rothschild Investment LLC 0.00% Add +5.0% 966 $3K
Optiver Holding B.V. 0.00% Reduce -56.6% 938 $3K
Bessemer Group Inc. 0.00% No change 932 $3K
Optima Capital LLC 0.00% New 778 $3K
Daiwa Securities Group Inc. 0.00% No change 573 $2K
Rockefeller Capital Management L.P. 0.00% Reduce -17.2% 548 $2K
Sunbelt Securities, Inc. 0.00% No change 444 $1K
Flagship Harbor Advisors, LLC 0.00% New 300 $1K
Avion Wealth 0.00% No change 408 $1K
CoreCap Advisors, LLC 0.00% No change 235 $792
Pinnacle Wealth Planning Services, Inc. 0.00% New 201 $677
Clean Yield Group 0.00% No change 85 $286
Torren Management, LLC 0.00% — 72 $243
SBI Securities Co., Ltd. 0.00% Reduce -2.9% 66 $222
Farther Finance Advisors, LLC 0.00% New 52 $175
Garner Asset Management Corp 0.00% New 50 $169
Clearstead Advisors, LLC 0.00% Reduce -98.7% 41 $139
Blue Trust, Inc. 0.00% No change 34 $115
Arax Advisory Partners 0.00% Reduce -100.0% 23 $78
SJS Investment Consulting Inc. 0.00% New 21 $71
Steward Partners Investment Advisory, LLC 0.00% No change 17 $57
Smartleaf Asset Management LLC 0.00% New 1 $3
Covestor Ltd 0.00% No change 94 $0

"% of holder's portfolio" is IRWD's weight in each manager's 13F, not the share of Ironwood Pharmaceuticals Inc. the manager owns.