Kalaris TherapeuticsKLRS

13F holders, Q4 2025 (December 31)
51holders +19
21new positions
5sold out
1famous investor
$8.44avg. 13F price*

At the end of Q4 2025, 51 institutions reported holding Kalaris Therapeutics Inc. (KLRS) in their 13F filings, up 19 from Q3 2025. 21 opened new positions and 5 sold out. The largest holders were Samsara Biocapital, LLC ($109.3M), RTW Investments, LP ($11.0M) and Paradigm Biocapital Advisors LP ($5.9M). One famous investor held it Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).

Company
Kalaris Therapeutics Inc.
CUSIP
482929106
Latest filing quarter
Q2 2026

History

Number of 13F holders

0204060 Q1 2025: 32Q1 2025Q2 2025: 30Q2 2025Q3 2025: 32Q3 2025Q4 2025: 51Q4 2025Q1 2026: 58Q1 2026Q2 2026: 56Q2 2026

Total Exit/New Position Q3 2025 → Q4 2025

InstitutionsTotal Value
New Positions21$28.3M
Exits5$2.6M

All 13F filers, Q3 2025 → Q4 2025: 5,161,346 shares bought and 629,529 shares sold, net +4,531,817 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 51 holders

Samsara Biocapital, LLC 11.28% Add +13.1% 12,948,081 $109.3M
RTW Investments, LP 0.11% New 1,300,000 $11.0M
Paradigm Biocapital Advisors LP 0.16% New 700,000 $5.9M
Siren, L.L.C. 0.11% Add +36.9% 435,798 $3.7M
Alyeska Investment Group, L.P. 0.01% New 403,551 $3.4M
Ikarian Capital, LLC 0.39% New 360,000 $3.0M
Vanguard Group Inc. 0.00% Add +44.2% 292,790 $2.5M
Kalehua Capital Management LLC 1.17% — 139,901 $1.2M
ADAR1 Capital Management, LLC 0.06% New 100,000 $844K
Woodline Partners LP 0.00% Reduce -58.5% 100,000 $844K
WHI TRUST Co LLC 0.63% — 97,493 $823K
Boothbay Fund Management, LLC 0.02% New 92,261 $779K
Raymond James Financial Inc. 0.00% New 88,436 $746K
Renaissance Technologies 0.00% Reduce -22.2% 87,751 $741K
Redmile Group, LLC 0.05% No change 82,955 $700K
Geode Capital Management, LLC 0.00% Add +28.0% 82,647 $698K
683 Capital Management, LLC 0.06% New 80,590 $680K
Marshall Wace, LLP 0.00% Add +416.3% 72,876 $615K
Propel Bio Management, LLC 0.30% New 42,053 $355K
Fortis Capital Advisors, LLC 0.05% No change 40,000 $338K
Belpointe Asset Management LLC 0.01% No change 40,000 $338K
BlackRock, Inc. 0.00% Reduce -4.8% 38,454 $325K
Goldman Sachs Group Inc. 0.00% Add +52.7% 34,303 $290K
Jane Street Group, LLC 0.00% New 33,114 $279K
OMERS ADMINISTRATION Corp 0.00% New 30,000 $253K
Morgan Stanley 0.00% Add +12.2% 27,948 $236K
Two Sigma Investments, LP 0.00% New 27,759 $234K
State Street Corp. 0.00% Add +12.4% 25,410 $214K
Squarepoint Ops LLC 0.00% Reduce -36.9% 25,367 $214K
Bridgeway Capital Management, LLC 0.00% No change 22,500 $190K
Simplify Asset Management Inc. 0.00% New 20,074 $169K
RBF Capital, LLC 0.01% No change 17,391 $147K
Northern Trust Corp. 0.00% New 13,654 $115K
Susquehanna International Group, LLP 0.00% New 12,856 $109K
Walleye Capital LLC 0.00% New 11,225 $95K
XTX Topco Ltd 0.00% New 10,897 $92K
Keel Point, LLC 0.01% New 10,225 $86K
Connor, Clark & Lunn Investment Management Ltd. 0.00% New 10,159 $86K
Johnson Financial Group, Inc. 0.00% No change 10,000 $84K
FMR LLC 0.00% No change 7,806 $66K
Bank of America Corp. 0.00% Add +2989.4% 6,704 $57K
Barclays PLC 0.00% New 6,065 $51K
Nano Cap New Millennium Growth Fund L P 0.03% — 4,000 $34K
UBS Group AG 0.00% Reduce -48.8% 2,691 $23K
Royal Bank of Canada 0.00% Add +32.9% 113 $1K
Fortitude Family Office, LLC 0.00% New 114 $962
BNP Paribas Financial Markets 0.00% Reduce -63.1% 52 $439
JPMorgan Chase & Co. 0.00% No change 50 $422
Parallel Advisors, LLC 0.00% No change 49 $414
SBI Securities Co., Ltd. 0.00% Reduce -37.5% 5 $42
Citigroup Inc. 0.00% No change 1 $8

"% of holder's portfolio" is KLRS's weight in each manager's 13F, not the share of Kalaris Therapeutics Inc. the manager owns.