Lyra TherapeuticsLYRA

13F holders, Q2 2024 (June 30)
51holders −28
13new positions
42sold out
2famous investors
$0.28avg. 13F price*

At the end of Q2 2024, 51 institutions reported holding Lyra Therapeutics Inc. (LYRA) in their 13F filings, down 28 from Q1 2024. 13 opened new positions and 42 sold out. The largest holders were Perceptive Advisors LLC ($3.5M), Citadel Advisors ($1.3M) and BlackRock Inc. ($783K). 2 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).

Company
Lyra Therapeutics Inc.
CUSIP
55234L105
Latest filing quarter
Q2 2025

History

Number of 13F holders

020406080 Q1 2024: 79Q1 2024Q2 2024: 51Q2 2024Q3 2024: 62Q3 2024Q4 2024: 54Q4 2024Q1 2025: 57Q1 2025Q2 2025: 1Q2 2025

Total Exit/New Position Q1 2024 → Q2 2024

InstitutionsTotal Value
New Positions13$498K
Exits42$112.3M

All 13F filers, Q1 2024 → Q2 2024: 7,439,864 shares bought and 20,280,673 shares sold, net −12,840,809 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 51 holders

Perceptive Advisors LLC 0.09% No change 12,757,562 $3.5M
Citadel Advisors 0.00% Add +10.0% 4,772,816 $1.3M
BlackRock Inc. 0.00% Add +1762.8% 2,829,978 $783K
Samsara Biocapital, LLC 0.16% No change 2,780,261 $769K
Vanguard Group Inc. 0.00% Add +16.8% 1,730,915 $479K
Ikarian Capital, LLC 0.09% No change 1,056,829 $292K
Rosalind Advisors, Inc. 0.23% Reduce -9.6% 1,034,773 $286K
Acadian Asset Management LLC 0.00% New 985,631 $271K
Morgan Stanley 0.00% Add +1160.6% 811,745 $225K
Geode Capital Management, LLC 0.00% Add +110.1% 755,095 $209K
Two Sigma Advisers, LP 0.00% Add +373.7% 681,600 $189K
Two Sigma Investments, LP 0.00% Add +167.2% 490,861 $136K
New York State Common Retirement Fund 0.00% New 382,900 $106K
State Street Corp. 0.00% Add +105.9% 259,820 $72K
Boothbay Fund Management, LLC 0.00% No change 232,670 $64K
Simplex Trading, LLC 0.00% New 129,141 $35K
Clearline Capital LP 0.00% No change 119,128 $33K
Charles Schwab Investment Management Inc. 0.00% New 111,609 $31K
Bank of America Corp. 0.00% Reduce -45.8% 86,459 $24K
Northern Trust Corp. 0.00% Add +38.6% 83,860 $23K
Bank of New York Mellon Corp 0.00% New 77,423 $21K
Alpine Global Management, LLC 0.00% New 46,439 $13K
Rhumbline Advisers 0.00% Add +14557.1% 43,385 $12K
Jane Street Group, LLC 0.00% Reduce -72.9% 42,676 $12K
Susquehanna International Group, LLP 0.00% Reduce -89.8% 35,160 $10K
XTX Topco Ltd 0.00% New 33,951 $9K
Alliancebernstein L.P. 0.00% New 33,120 $9K
Virtu Financial LLC 0.00% Add +165.7% 31,690 $9K
Letko, Brosseau & Associates Inc. 0.00% No change 31,900 $9K
Y-Intercept (Hong Kong) Ltd 0.00% Add +34.0% 27,516 $8K
Corebridge Financial, Inc. 0.00% — 26,036 $7K
Goldman Sachs Group Inc. 0.00% Reduce -92.7% 24,391 $7K
Invesco Ltd. 0.00% Reduce -95.9% 22,824 $6K
Dimensional Fund Advisors LP 0.00% Reduce -88.8% 21,471 $6K
JPMorgan Chase & Co. 0.00% Reduce -81.1% 20,659 $6K
Millennium Management 0.00% Reduce -95.0% 20,350 $6K
Wells Fargo & Company 0.00% Add +6919.1% 17,618 $5K
Barclays PLC 0.00% Reduce -49.4% 16,604 $5K
UBS Group AG 0.00% Add +81550.0% 14,697 $4K
DLK Investment Management, LLC 0.00% No change 12,000 $3K
Citigroup Inc. 0.00% Reduce -91.0% 10,652 $3K
Tower Research Capital LLC (TRC) 0.00% Reduce -23.5% 6,822 $2K
Ameritas Investment Partners, Inc. 0.00% New 4,741 $1K
National Bank of Canada 0.00% No change 3,700 $1K
Royal Bank of Canada 0.00% Add +645.1% 4,873 $1K
California State Teachers Retirement System 0.00% New 3,507 $970
Osaic Holdings, Inc. 0.00% Reduce -31.1% 1,378 $383
Comerica Bank 0.00% No change 1,159 $321
Farther Finance Advisors, LLC 0.00% New 38 $11
T. Rowe Price Associates Inc. 0.00% New 17,541 $0
Amalgamated Bank 0.00% New 1,674 $0

"% of holder's portfolio" is LYRA's weight in each manager's 13F, not the share of Lyra Therapeutics Inc. the manager owns.