Lyra TherapeuticsLYRA
13F holders, Q1 2025 (March 31)57holders +3
6new positions
3sold out
1famous investor
$0.13avg. 13F price*
At the end of Q1 2025, 57 institutions reported holding Lyra Therapeutics Inc. (LYRA) in their 13F filings, up 3 from Q4 2024. 6 opened new positions and 3 sold out. The largest holders were Perceptive Advisors LLC ($1.6M), BlackRock, Inc. ($381K) and Vanguard Group Inc. ($222K). One famous investor held it Cliff Asness (0.0% of AQR Capital Management's portfolio).
- Company
- Lyra Therapeutics Inc.
- CUSIP
- 55234L105
- Latest filing quarter
- Q2 2025
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 6 | $13K |
| Exits | 3 | $91K |
All 13F filers, Q4 2024 → Q1 2025: 498,096 shares bought and 1,788,805 shares sold, net −1,290,709 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 57 holders
| Perceptive Advisors LLC | 0.06% | No change | 12,757,562 | $1.6M |
| BlackRock, Inc. | 0.00% | Reduce -2.9% | 3,018,986 | $381K |
| Vanguard Group Inc. | 0.00% | Reduce -1.2% | 1,765,585 | $222K |
| Samsara Biocapital, LLC | 0.03% | Reduce -29.3% | 1,390,130 | $176K |
| Ikarian Capital, LLC | 0.04% | No change | 1,058,148 | $134K |
| Geode Capital Management, LLC | 0.00% | Add +14.7% | 1,016,004 | $128K |
| ADAR1 Capital Management, LLC | 0.01% | No change | 533,200 | $67K |
| State Street Corp. | 0.00% | No change | 488,720 | $62K |
| UBS Group AG | 0.00% | Add +2.2% | 434,226 | $55K |
| Goldman Sachs Group Inc. | 0.00% | Reduce -33.4% | 370,194 | $47K |
| Two Sigma Advisers, LP | 0.00% | Reduce -5.5% | 364,478 | $46K |
| Northern Trust Corp. | 0.00% | Add +16.2% | 332,639 | $42K |
| BNP Paribas Financial Markets | 0.00% | Reduce -1.0% | 242,546 | $31K |
| Boothbay Fund Management, LLC | 0.00% | No change | 233,989 | $30K |
| Susquehanna International Group, LLP | 0.00% | Add +110.3% | 217,567 | $27K |
| Two Sigma Investments, LP | 0.00% | Reduce -8.0% | 193,145 | $24K |
| New York State Common Retirement Fund | 0.00% | No change | 154,800 | $20K |
| Charles Schwab Investment Management Inc. | 0.00% | No change | 111,609 | $14K |
| Rhumbline Advisers | 0.00% | Add +112.6% | 87,710 | $11K |
| Bank of New York Mellon Corp | 0.00% | Reduce -5.8% | 71,585 | $9K |
| Morgan Stanley | 0.00% | Reduce -69.7% | 65,619 | $8K |
| FMR LLC | 0.00% | Reduce -41.7% | 58,213 | $7K |
| AQR Capital Management | 0.00% | Add +102.1% | 58,041 | $7K |
| JPMorgan Chase & Co. | 0.00% | Reduce -64.0% | 56,277 | $7K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +32.5% | 52,736 | $7K |
| Barclays PLC | 0.00% | Reduce -33.5% | 50,038 | $6K |
| Jane Street Group, LLC | 0.00% | New | 43,997 | $6K |
| Citigroup Inc. | 0.00% | Reduce -7.7% | 35,177 | $4K |
| Alliancebernstein L.P. | 0.00% | No change | 33,120 | $4K |
| Sei Investments Co. | 0.00% | Reduce -64.2% | 30,067 | $4K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +4.5% | 29,018 | $4K |
| Wells Fargo & Company | 0.00% | Add +2.3% | 25,305 | $3K |
| T. Rowe Price Associates Inc. | 0.00% | No change | 17,541 | $3K |
| Corebridge Financial, Inc. | 0.00% | Reduce -1.5% | 23,709 | $3K |
| Invesco Ltd. | 0.00% | No change | 23,626 | $3K |
| Bank of America Corp. | 0.00% | Reduce -59.5% | 21,352 | $3K |
| Intech Investment Management LLC | 0.00% | New | 16,560 | $2K |
| SG Americas Securities, LLC | 0.00% | Reduce -54.2% | 14,620 | $2K |
| Squarepoint Ops LLC | 0.00% | New | 15,283 | $2K |
| Abel Hall, LLC | 0.00% | Reduce -30.8% | 12,214 | $2K |
| Cibc World Markets Corp. | 0.00% | New | 10,739 | $1K |
| ProShare Advisors LLC | 0.00% | Reduce -23.1% | 10,477 | $1K |
| Sassicaia Capital Advisers LLC | 0.00% | New | 10,000 | $1K |
| Royal Bank of Canada | 0.00% | Add +51.5% | 8,019 | $1K |
| Cwm, LLC | 0.00% | Add +24.3% | 6,677 | $1K |
| Northwestern Mutual Wealth Management Co. | 0.00% | New | 6,000 | $758 |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 4,741 | $599 |
| SBI Securities Co., Ltd. | 0.00% | Add +0.1% | 4,272 | $540 |
| California State Teachers Retirement System | 0.00% | No change | 3,507 | $443 |
| Comerica Bank | 0.00% | No change | 1,159 | $146 |
| Wilmington Savings Fund Society, FSB | 0.00% | No change | 1,025 | $129 |
| Jones Financial Companies LLLP | 0.00% | No change | 500 | $69 |
| Nisa Investment Advisors, LLC | 0.00% | No change | 500 | $63 |
| EverSource Wealth Advisors, LLC | 0.00% | Add +188.2% | 343 | $43 |
| Sterling Capital Management LLC | 0.00% | No change | 88 | $11 |
| Amalgamated Bank | 0.00% | No change | 1,674 | $0 |
| Simplex Trading, LLC | 0.00% | Add +262.8% | 1,317 | $0 |
"% of holder's portfolio" is LYRA's weight in each manager's 13F, not the share of Lyra Therapeutics Inc. the manager owns.