Lyra TherapeuticsLYRA

13F holders, Q2 2025 (June 30)
30holders
$8.96avg. 13F price*

At the end of Q2 2025, 30 institutions reported holding Lyra Therapeutics Inc. (LYRA) in their 13F filings. The largest holders were Perceptive Advisors LLC ($2.3M), Sabby Management, LLC ($1.1M) and Vanguard Group Inc. ($261K).

Company
Lyra Therapeutics Inc.
CUSIP
55234L204
Latest filing quarter
Q1 2026

History

Number of 13F holders

0102030 Q2 2025: 30Q2 2025Q3 2025: 26Q3 2025Q4 2025: 23Q4 2025Q1 2026: 1Q1 2026

Total Exit/New Position Q2 2025

InstitutionsTotal Value
New Positions8$1.2M
Exits0$0

Ownership 30 holders

Perceptive Advisors LLC 0.09% No change 255,150 $2.3M
Sabby Management, LLC 9.11% New 125,729 $1.1M
Vanguard Group Inc. 0.00% Reduce -17.4% 29,178 $261K
Bank of America Corp. 0.00% Add +6583.7% 28,542 $256K
Ikarian Capital, LLC 0.06% No change 21,161 $190K
Geode Capital Management, LLC 0.00% Reduce -45.9% 10,986 $98K
State of Wisconsin Investment Board 0.00% New 10,500 $94K
Morgan Stanley 0.00% Add +64.9% 2,164 $19K
FMR LLC 0.00% Add +50.1% 1,748 $16K
BlackRock, Inc. 0.00% Reduce -97.2% 1,690 $15K
Russell Investments Group, Ltd. 0.00% New 1,594 $14K
Tower Research Capital LLC (TRC) 0.00% Add +40.6% 1,483 $13K
Royal Bank of Canada 0.00% Add +587.1% 1,102 $10K
Citigroup Inc. 0.00% Add +13.0% 795 $7K
Valley National Advisers Inc. 0.00% New 500 $4K
Signature Resources Capital Management, LLC 0.00% New 400 $4K
EverSource Wealth Advisors, LLC 0.00% Add +5118.7% 358 $3K
Cwm, LLC 0.00% Add +51.3% 202 $2K
JPMorgan Chase & Co. 0.00% Reduce -82.9% 192 $2K
SBI Securities Co., Ltd. 0.00% Reduce -0.5% 85 $762
Barclays PLC 0.00% Reduce -95.2% 48 $430
Wells Fargo & Company 0.00% Reduce -92.3% 39 $349
BNP Paribas Financial Markets 0.00% Reduce -99.5% 25 $224
Comerica Bank 0.00% Reduce -0.8% 23 $206
Principal Securities, Inc. 0.00% New 19 $170
Jones Financial Companies LLLP 0.00% No change 10 $91
Nisa Investment Advisors, LLC 0.00% No change 10 $90
Raymond James Financial Inc. 0.00% New 8 $72
IFP Advisors, Inc 0.00% New 6 $54
UBS Group AG 0.00% Reduce -100.0% 2 $18

"% of holder's portfolio" is LYRA's weight in each manager's 13F, not the share of Lyra Therapeutics Inc. the manager owns.