Lyra TherapeuticsLYRA
13F holders, Q3 2025 (September 30)26holders −4
4new positions
8sold out
1famous investor
$6.54avg. 13F price*
At the end of Q3 2025, 26 institutions reported holding Lyra Therapeutics Inc. (LYRA) in their 13F filings, down 4 from Q2 2025. 4 opened new positions and 8 sold out. The largest holders were Perceptive Advisors LLC ($1.5M), Sabby Management, LLC ($833K) and Vanguard Group Inc. ($189K). One famous investor held it Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Lyra Therapeutics Inc.
- CUSIP
- 55234L204
- Latest filing quarter
- Q1 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 4 | $129K |
| Exits | 8 | $113K |
All 13F filers, Q2 2025 → Q3 2025: 25,939 shares bought and 71,076 shares sold, net −45,137 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 26 holders
| Perceptive Advisors LLC | 0.04% | Reduce -10.1% | 229,382 | $1.5M |
| Sabby Management, LLC | 4.35% | Add +1.5% | 127,624 | $833K |
| Vanguard Group Inc. | 0.00% | Reduce -1.4% | 28,754 | $189K |
| Ikarian Capital, LLC | 0.03% | No change | 21,161 | $139K |
| Citadel Advisors | 0.00% | New | 19,484 | $128K |
| Geode Capital Management, LLC | 0.00% | No change | 10,986 | $72K |
| UBS Group AG | 0.00% | Add +199950.0% | 4,001 | $26K |
| BlackRock, Inc. | 0.00% | No change | 1,690 | $11K |
| Royal Bank of Canada | 0.00% | Add +20.2% | 1,325 | $9K |
| Morgan Stanley | 0.00% | Reduce -41.0% | 1,277 | $8K |
| Citigroup Inc. | 0.00% | Reduce -11.3% | 705 | $5K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -64.0% | 534 | $3K |
| FMR LLC | 0.00% | Reduce -76.8% | 406 | $3K |
| Signature Resources Capital Management, LLC | 0.00% | No change | 400 | $3K |
| EverSource Wealth Advisors, LLC | 0.00% | Reduce -3.6% | 345 | $2K |
| Jones Financial Companies LLLP | 0.00% | Add +2000.0% | 210 | $1K |
| Fortitude Family Office, LLC | 0.00% | New | 96 | $627 |
| SBI Securities Co., Ltd. | 0.00% | Reduce -5.9% | 80 | $522 |
| JPMorgan Chase & Co. | 0.00% | Reduce -85.9% | 27 | $178 |
| Comerica Bank | 0.00% | No change | 23 | $150 |
| Osaic Holdings, Inc. | 0.00% | New | 22 | $143 |
| Wilmington Savings Fund Society, FSB | 0.00% | New | 20 | $131 |
| Bank of America Corp. | 0.00% | Reduce -99.9% | 18 | $117 |
| BNP Paribas Financial Markets | 0.00% | Reduce -36.0% | 16 | $104 |
| IFP Advisors, Inc | 0.00% | Reduce -66.7% | 2 | $13 |
| Cwm, LLC | 0.00% | Reduce -88.1% | 24 | $0 |
"% of holder's portfolio" is LYRA's weight in each manager's 13F, not the share of Lyra Therapeutics Inc. the manager owns.