Lyra TherapeuticsLYRA
13F holders, Q4 2025 (December 31)23holders −3
3new positions
6sold out
$3.08avg. 13F price*
At the end of Q4 2025, 23 institutions reported holding Lyra Therapeutics Inc. (LYRA) in their 13F filings, down 3 from Q3 2025. 3 opened new positions and 6 sold out. The largest holders were Sabby Management, LLC ($539K), Ikarian Capital, LLC ($65K) and DRW Securities, LLC ($52K).
- Company
- Lyra Therapeutics Inc.
- CUSIP
- 55234L204
- Latest filing quarter
- Q1 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 3 | $79K |
| Exits | 6 | $1.8M |
All 13F filers, Q3 2025 → Q4 2025: 77,552 shares bought and 283,524 shares sold, net −205,972 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 23 holders
| Sabby Management, LLC | 4.52% | Add +37.3% | 175,158 | $539K |
| Ikarian Capital, LLC | 0.01% | No change | 21,161 | $65K |
| DRW Securities, LLC | 0.00% | New | 16,812 | $52K |
| Geode Capital Management, LLC | 0.00% | Add +11.5% | 12,249 | $38K |
| Artia Global Partners LP | 0.00% | New | 8,756 | $27K |
| BlackRock, Inc. | 0.00% | Add +41.7% | 2,394 | $7K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +310.3% | 2,191 | $7K |
| Royal Bank of Canada | 0.00% | Add +47.4% | 1,953 | $6K |
| UBS Group AG | 0.00% | Reduce -83.1% | 675 | $2K |
| EverSource Wealth Advisors, LLC | 0.00% | Reduce -2.0% | 338 | $1K |
| Morgan Stanley | 0.00% | Reduce -73.8% | 334 | $1K |
| Jones Financial Companies LLLP | 0.00% | No change | 210 | $647 |
| Bank of America Corp. | 0.00% | Add +1016.7% | 201 | $619 |
| SBI Securities Co., Ltd. | 0.00% | No change | 80 | $246 |
| JPMorgan Chase & Co. | 0.00% | No change | 27 | $83 |
| Comerica Bank | 0.00% | No change | 23 | $71 |
| Osaic Holdings, Inc. | 0.00% | No change | 22 | $67 |
| Wilmington Savings Fund Society, FSB | 0.00% | No change | 20 | $62 |
| BNP Paribas Financial Markets | 0.00% | No change | 16 | $49 |
| Global Retirement Partners, LLC | 0.00% | New | 15 | $46 |
| Citigroup Inc. | 0.00% | Reduce -99.6% | 3 | $9 |
| IFP Advisors, Inc | 0.00% | Reduce -50.0% | 1 | $3 |
| Cwm, LLC | 0.00% | Reduce -95.8% | 1 | $0 |
"% of holder's portfolio" is LYRA's weight in each manager's 13F, not the share of Lyra Therapeutics Inc. the manager owns.