Nektar TherapeuticsNKTR

13F holders, Q4 2025 (December 31)
172holders +27
50new positions
31sold out
4famous investors
$42.28avg. 13F price*

At the end of Q4 2025, 172 institutions reported holding Nektar Therapeutics (NKTR) in their 13F filings, up 27 from Q3 2025. 50 opened new positions and 31 sold out. The largest holders were BVF Inc. ($65.9M), Vanguard Group Inc. ($43.4M) and Two Seas Capital LP ($31.5M). 4 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).

Company
Nektar Therapeutics
CUSIP
640268306
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150200250 Q2 2025: 101Q2 2025Q3 2025: 145Q3 2025Q4 2025: 172Q4 2025Q1 2026: 208Q1 2026Q2 2026: 238Q2 2026

Total Exit/New Position Q3 2025 → Q4 2025

InstitutionsTotal Value
New Positions50$105.3M
Exits31$79.7M

All 13F filers, Q3 2025 → Q4 2025: 6,419,708 shares bought and 3,806,405 shares sold, net +2,613,303 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 172 holders

BVF Inc. 2.22% Add +22.2% 1,559,595 $65.9M
Vanguard Group Inc. 0.00% Add +8.3% 1,027,089 $43.4M
Two Seas Capital LP 1.85% New 745,185 $31.5M
BlackRock, Inc. 0.00% Add +6.0% 645,607 $27.3M
Armistice Capital, LLC 0.62% Add +122.4% 596,000 $25.2M
Morgan Stanley 0.00% Reduce -39.0% 566,421 $23.9M
Prosight Management, LP 4.85% New 554,633 $23.4M
Two Sigma Investments, LP 0.03% Add +8.9% 473,014 $20.0M
Invesco Ltd. 0.00% Add +106.3% 468,159 $19.8M
Millennium Management 0.01% Reduce -16.8% 454,075 $19.2M
Sofinnova Investments, Inc. 0.80% Add +270.4% 438,630 $18.5M
Point72 Asset Management 0.03% Add +250.5% 433,419 $18.3M
Emerald Advisers, LLC 0.50% Add +18.9% 384,342 $16.2M
Susquehanna International Group, LLP 0.02% Reduce -58.6% 383,310 $16.2M
22NW, LP 5.89% No change 331,115 $14.0M
Qube Research & Technologies Ltd 0.02% Add +8050.9% 323,915 $13.7M
Citadel Advisors 0.01% Reduce -14.2% 309,777 $13.1M
Two Sigma Advisers, LP 0.03% Add +72.4% 308,414 $13.0M
Voloridge Investment Management, LLC 0.04% Add +72.2% 295,716 $12.5M
UBS Group AG 0.00% Add +216.6% 287,561 $12.2M
Balyasny Asset Management L.P. 0.02% Add +54.3% 282,021 $11.9M
Primecap Management Co. 0.01% Reduce -3.1% 280,150 $11.8M
Geode Capital Management, LLC 0.00% Add +12.9% 254,361 $10.8M
Emerald Mutual Fund Advisers Trust 0.52% Add +8.5% 253,125 $10.7M
Jane Street Group, LLC 0.01% New 218,337 $9.2M
Great Point Partners LLC 2.89% Reduce -29.8% 210,732 $8.9M
BNP Paribas Financial Markets 0.01% Add +48355.8% 210,298 $8.9M
Gilder Gagnon Howe & Co. LLC 0.09% Reduce -7.3% 208,302 $8.8M
State Street Corp. 0.00% Add +51.7% 195,656 $8.3M
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. 0.71% Add +22.3% 188,112 $8.0M
Creek Drive Management Group LLC 5.84% — 185,500 $7.8M
Stempoint Capital LP 1.29% Add +235.1% 178,274 $7.5M
HRT Financial LP 0.02% Add +1218.2% 173,443 $7.3M
Renaissance Technologies 0.01% Reduce -37.9% 172,881 $7.3M
JPMorgan Chase & Co. 0.00% Add +793605.3% 150,804 $6.4M
Goldman Sachs Group Inc. 0.00% Add +91.8% 147,793 $6.2M
Charles Schwab Investment Management Inc. 0.00% Add +5.0% 120,380 $5.1M
Nantahala Capital Management, LLC 0.29% Reduce -73.0% 112,946 $4.8M
Jefferies Financial Group Inc. 0.04% Reduce -63.1% 111,900 $4.7M
Woodline Partners LP 0.02% Reduce -55.4% 104,000 $4.4M
Connor, Clark & Lunn Investment Management Ltd. 0.01% Add +108.1% 101,166 $4.3M
FMR LLC 0.00% Add +153.0% 101,129 $4.3M
ING Groep NV 0.03% New 100,000 $4.2M
Monashee Investment Management LLC 2.35% New 94,134 $4.0M
Deutsche Bank AG 0.00% Add +0.8% 90,743 $3.8M
Quinn Opportunity Partners LLC 0.16% Reduce -21.8% 85,868 $3.6M
Russell Investments Group, Ltd. 0.00% Add +402.5% 85,666 $3.6M
Stonepine Capital Management, LLC 2.84% No change 85,000 $3.6M
Propel Bio Management, LLC 2.99% Add +69.0% 82,822 $3.5M
DAFNA Capital Management LLC 0.75% Add +36.4% 74,998 $3.2M
Acadian Asset Management LLC 0.01% Add +164.3% 72,241 $3.0M
ADAR1 Capital Management, LLC 0.23% Add +0.0% 72,031 $3.0M
Tetragon Partners GP Ltd 0.62% New 69,287 $2.9M
Voleon Capital Management LP 0.06% New 68,335 $2.9M
Nearwater Capital Markets, Ltd 0.04% New 61,500 $2.6M
Landscape Capital Management, L.L.C. 0.17% New 60,431 $2.6M
Hudson Bay Capital Management LP 0.02% Reduce -44.6% 59,691 $2.5M
F/m Investments LLC 0.09% Add +9.5% 58,123 $2.5M
Northern Trust Corp. 0.00% Add +45.7% 56,076 $2.4M
Moody Aldrich Partners LLC 0.44% Reduce -24.0% 56,023 $2.4M
Aquatic Capital Management LLC 0.07% New 55,240 $2.3M
Fred Alger Management, LLC 0.01% Reduce -41.2% 54,020 $2.3M
Cambridge Investment Research Advisors, Inc. 0.01% Add +15.2% 53,713 $2.3M
Jump Financial, LLC 0.03% New 53,212 $2.2M
Act Capital Management, LLC 1.75% — 51,200 $2.2M
Norges Bank 0.00% — 50,000 $2.1M
Dark Forest Capital Management LP 0.08% Add +360.3% 42,277 $1.8M
Headlands Technologies LLC 0.15% Add +38.1% 41,201 $1.7M
AWM Investment Company, Inc. 0.16% No change 40,000 $1.7M
Deuterium Capital Management, LLC 2.29% No change 37,349 $1.6M
Engineers Gate Manager LP 0.02% Add +111.5% 37,284 $1.6M
Citigroup Inc. 0.00% Add +1074.2% 35,777 $1.5M
Caption Management, LLC 0.07% New 35,000 $1.5M
Swiss National Bank 0.00% New 31,900 $1.3M
SummitTX Capital, L.P. 0.04% Add +361.2% 31,353 $1.3M
Birchview Capital, LP 0.77% Add +671.0% 31,000 $1.3M
Erste Asset Management GmbH 0.01% Add +64.7% 28,000 $1.2M
Simplify Asset Management Inc. 0.02% Reduce -67.9% 28,000 $1.2M
KVP Capital Advisors, LP 1.17% — 26,900 $1.1M
Fox Run Management, L.L.C. 0.17% New 26,522 $1.1M
Bank of America Corp. 0.00% Reduce -45.6% 26,092 $1.1M
Marshall Wace, LLP 0.00% New 24,023 $1.0M
Gsa Capital Partners LLP 0.08% New 23,114 $977K
Simplex Trading, LLC 0.03% Reduce -71.3% 21,936 $927K
BIT Capital GmbH 0.04% New 21,100 $892K
Squarepoint Ops LLC 0.00% Reduce -41.3% 20,257 $856K
Ishara Investments LP 0.98% — 20,000 $846K
Trexquant Investment LP 0.01% Reduce -79.4% 18,821 $796K
J. Goldman & Co LP 0.03% New 18,352 $776K
Jain Global LLC 0.01% Reduce -47.2% 17,299 $731K
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% New 16,184 $684K
Susquehanna Portfolio Strategies, LLC 0.01% No change 16,057 $679K
Knott David M Jr 0.30% New 15,500 $655K
Barclays PLC 0.00% Reduce -7.4% 15,444 $653K
Algert Global LLC 0.01% New 15,310 $647K
Seven Fleet Capital Management LP 0.43% — 15,000 $634K
Palumbo Wealth Management LLC 0.15% Reduce -43.7% 14,714 $622K
Jacobs Levy Equity Management, Inc. 0.00% Reduce -2.6% 14,564 $616K
California State Teachers Retirement System 0.00% New 14,520 $614K
Virtu Financial LLC 0.02% New 13,811 $584K
Gainplan LLC 0.21% Add +168.1% 13,500 $571K
Sectoral Asset Management Inc. 0.46% New 13,485 $570K
Cibc World Market Inc. 0.00% New 13,282 $562K
Informed Momentum Co LLC 0.06% Reduce -83.4% 12,972 $548K
Legal & General Group Plc 0.00% New 12,413 $525K
HighVista Strategies LLC 0.13% New 11,749 $497K
SG Americas Securities, LLC 0.00% New 10,954 $463K
Y-Intercept (Hong Kong) Ltd 0.01% New 10,862 $459K
T. Rowe Price Associates Inc. 0.00% Reduce -13.4% 10,376 $439K
Sei Investments Co. 0.00% Reduce -25.1% 10,292 $435K
Iridian Asset Management LLC 0.15% New 9,728 $411K
HB Wealth Management, LLC 0.00% No change 9,244 $391K
Sigma Planning Corp 0.01% New 9,000 $381K
State of Wisconsin Investment Board 0.00% New 8,629 $365K
Glenmede Trust Co. NA 0.00% — 8,590 $363K
Janus Henderson Group PLC 0.00% New 8,100 $342K
Leonteq Securities AG 0.02% New 8,000 $338K
WINTON GROUP Ltd 0.01% New 7,765 $328K
OMERS ADMINISTRATION Corp 0.00% New 7,200 $304K
XTX Topco Ltd 0.01% Add +22.0% 7,196 $304K
Verition Fund Management LLC 0.00% Reduce -71.2% 7,035 $297K
Royal Bank of Canada 0.00% Reduce -82.2% 7,005 $296K
Tower Research Capital LLC (TRC) 0.01% Add +1070.7% 5,561 $235K
FORA Capital, LLC 0.03% New 5,761 $232K
Osaic Holdings, Inc. 0.00% Reduce -0.7% 5,388 $228K
Envestnet Asset Management Inc. 0.00% Reduce -46.6% 5,384 $228K
Opal Capital LLC 0.06% — 5,948 $220K
FNY Investment Advisers, LLC 0.06% Add +99.8% 5,200 $219K
Arrowpoint Investment Partners (Singapore) Pte. Ltd. 0.03% New 4,927 $208K
Virtus Investment Advisers, LLC 0.06% New 4,863 $206K
KLP Kapitalforvaltning As 0.00% New 3,500 $148K
Bayforest Capital Ltd 0.08% Add +51.3% 2,541 $107K
Flagship Harbor Advisors, LLC 0.00% New 2,179 $92K
Quarry LP 0.01% New 2,000 $85K
Bessemer Group Inc. 0.00% Add +1.0% 1,580 $66K
Group One Trading LLC 0.00% Reduce -83.0% 1,448 $61K
US Bancorp \de 0.00% Reduce -30.4% 1,260 $53K
Natixis 0.00% New 685 $29K
Allworth Financial LP 0.00% No change 676 $29K
Canada Pension Plan Investment Board 0.00% New 400 $17K
Steward Partners Investment Advisory, LLC 0.00% No change 213 $9K
Cwm, LLC 0.00% Reduce -15.6% 205 $9K
Founders Capital Management 0.00% New 200 $8K
Activest Wealth Management 0.00% No change 200 $8K
Wells Fargo & Company 0.00% Reduce -23.0% 191 $8K
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.00% New 178 $8K
Los Angeles Capital Management LLC 0.00% New 127 $8K
SBI Securities Co., Ltd. 0.00% Reduce -6.4% 146 $6K
Jones Financial Companies LLLP 0.00% Reduce -5.2% 109 $5K
Rhumbline Advisers 0.00% No change 100 $4K
CIBC Private Wealth Group LLC 0.00% No change 100 $4K
EFG International AG 0.00% — 75 $3K
Signaturefd, LLC 0.00% Reduce -73.1% 70 $3K
Keating Financial Advisory Services, Inc. 0.00% — 69 $3K
MTM Investment Management, LLC 0.00% No change 66 $3K
Brown Brothers Harriman & Co. 0.00% No change 66 $3K
SJS Investment Consulting Inc. 0.00% New 58 $2K
MassMutual Private Wealth & Trust, FSB 0.00% Reduce -29.7% 45 $2K
Atlas Capital Advisors Inc. 0.00% — 40 $2K
Boreal Capital Management LLC 0.00% No change 36 $2K
Rachor Investment Advisory Services, LLC 0.00% — 35 $1K
Global Retirement Partners, LLC 0.00% No change 27 $1K
Nisa Investment Advisors, LLC 0.00% Reduce -20.0% 20 $846
ORG Partners LLC 0.00% No change 20 $845
Ameriflex Group, Inc. 0.00% Reduce -50.0% 13 $550
Medallion Wealth Advisors, LLC 0.00% No change 13 $550
Kimelman & Baird, LLC 0.00% No change 13 $550
Arlington Trust Co LLC 0.00% No change 6 $254
Danske Bank A/S 0.00% No change 2 $85
Arax Advisory Partners 0.00% Reduce -77.8% 2 $85
Smartleaf Asset Management LLC 0.00% New 2 $84
Amalgamated Bank 0.00% No change 1 $0

"% of holder's portfolio" is NKTR's weight in each manager's 13F, not the share of Nektar Therapeutics the manager owns.