Nektar TherapeuticsNKTR
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 172 institutions reported holding Nektar Therapeutics (NKTR) in their 13F filings, up 27 from Q3 2025. 50 opened new positions and 31 sold out. The largest holders were BVF Inc. ($65.9M), Vanguard Group Inc. ($43.4M) and Two Seas Capital LP ($31.5M). 4 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).
- Company
- Nektar Therapeutics
- CUSIP
- 640268306
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 50 | $105.3M |
| Exits | 31 | $79.7M |
All 13F filers, Q3 2025 → Q4 2025: 6,419,708 shares bought and 3,806,405 shares sold, net +2,613,303 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 172 holders
| BVF Inc. | 2.22% | Add +22.2% | 1,559,595 | $65.9M |
| Vanguard Group Inc. | 0.00% | Add +8.3% | 1,027,089 | $43.4M |
| Two Seas Capital LP | 1.85% | New | 745,185 | $31.5M |
| BlackRock, Inc. | 0.00% | Add +6.0% | 645,607 | $27.3M |
| Armistice Capital, LLC | 0.62% | Add +122.4% | 596,000 | $25.2M |
| Morgan Stanley | 0.00% | Reduce -39.0% | 566,421 | $23.9M |
| Prosight Management, LP | 4.85% | New | 554,633 | $23.4M |
| Two Sigma Investments, LP | 0.03% | Add +8.9% | 473,014 | $20.0M |
| Invesco Ltd. | 0.00% | Add +106.3% | 468,159 | $19.8M |
| Millennium Management | 0.01% | Reduce -16.8% | 454,075 | $19.2M |
| Sofinnova Investments, Inc. | 0.80% | Add +270.4% | 438,630 | $18.5M |
| Point72 Asset Management | 0.03% | Add +250.5% | 433,419 | $18.3M |
| Emerald Advisers, LLC | 0.50% | Add +18.9% | 384,342 | $16.2M |
| Susquehanna International Group, LLP | 0.02% | Reduce -58.6% | 383,310 | $16.2M |
| 22NW, LP | 5.89% | No change | 331,115 | $14.0M |
| Qube Research & Technologies Ltd | 0.02% | Add +8050.9% | 323,915 | $13.7M |
| Citadel Advisors | 0.01% | Reduce -14.2% | 309,777 | $13.1M |
| Two Sigma Advisers, LP | 0.03% | Add +72.4% | 308,414 | $13.0M |
| Voloridge Investment Management, LLC | 0.04% | Add +72.2% | 295,716 | $12.5M |
| UBS Group AG | 0.00% | Add +216.6% | 287,561 | $12.2M |
| Balyasny Asset Management L.P. | 0.02% | Add +54.3% | 282,021 | $11.9M |
| Primecap Management Co. | 0.01% | Reduce -3.1% | 280,150 | $11.8M |
| Geode Capital Management, LLC | 0.00% | Add +12.9% | 254,361 | $10.8M |
| Emerald Mutual Fund Advisers Trust | 0.52% | Add +8.5% | 253,125 | $10.7M |
| Jane Street Group, LLC | 0.01% | New | 218,337 | $9.2M |
| Great Point Partners LLC | 2.89% | Reduce -29.8% | 210,732 | $8.9M |
| BNP Paribas Financial Markets | 0.01% | Add +48355.8% | 210,298 | $8.9M |
| Gilder Gagnon Howe & Co. LLC | 0.09% | Reduce -7.3% | 208,302 | $8.8M |
| State Street Corp. | 0.00% | Add +51.7% | 195,656 | $8.3M |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | 0.71% | Add +22.3% | 188,112 | $8.0M |
| Creek Drive Management Group LLC | 5.84% | — | 185,500 | $7.8M |
| Stempoint Capital LP | 1.29% | Add +235.1% | 178,274 | $7.5M |
| HRT Financial LP | 0.02% | Add +1218.2% | 173,443 | $7.3M |
| Renaissance Technologies | 0.01% | Reduce -37.9% | 172,881 | $7.3M |
| JPMorgan Chase & Co. | 0.00% | Add +793605.3% | 150,804 | $6.4M |
| Goldman Sachs Group Inc. | 0.00% | Add +91.8% | 147,793 | $6.2M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +5.0% | 120,380 | $5.1M |
| Nantahala Capital Management, LLC | 0.29% | Reduce -73.0% | 112,946 | $4.8M |
| Jefferies Financial Group Inc. | 0.04% | Reduce -63.1% | 111,900 | $4.7M |
| Woodline Partners LP | 0.02% | Reduce -55.4% | 104,000 | $4.4M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.01% | Add +108.1% | 101,166 | $4.3M |
| FMR LLC | 0.00% | Add +153.0% | 101,129 | $4.3M |
| ING Groep NV | 0.03% | New | 100,000 | $4.2M |
| Monashee Investment Management LLC | 2.35% | New | 94,134 | $4.0M |
| Deutsche Bank AG | 0.00% | Add +0.8% | 90,743 | $3.8M |
| Quinn Opportunity Partners LLC | 0.16% | Reduce -21.8% | 85,868 | $3.6M |
| Russell Investments Group, Ltd. | 0.00% | Add +402.5% | 85,666 | $3.6M |
| Stonepine Capital Management, LLC | 2.84% | No change | 85,000 | $3.6M |
| Propel Bio Management, LLC | 2.99% | Add +69.0% | 82,822 | $3.5M |
| DAFNA Capital Management LLC | 0.75% | Add +36.4% | 74,998 | $3.2M |
| Acadian Asset Management LLC | 0.01% | Add +164.3% | 72,241 | $3.0M |
| ADAR1 Capital Management, LLC | 0.23% | Add +0.0% | 72,031 | $3.0M |
| Tetragon Partners GP Ltd | 0.62% | New | 69,287 | $2.9M |
| Voleon Capital Management LP | 0.06% | New | 68,335 | $2.9M |
| Nearwater Capital Markets, Ltd | 0.04% | New | 61,500 | $2.6M |
| Landscape Capital Management, L.L.C. | 0.17% | New | 60,431 | $2.6M |
| Hudson Bay Capital Management LP | 0.02% | Reduce -44.6% | 59,691 | $2.5M |
| F/m Investments LLC | 0.09% | Add +9.5% | 58,123 | $2.5M |
| Northern Trust Corp. | 0.00% | Add +45.7% | 56,076 | $2.4M |
| Moody Aldrich Partners LLC | 0.44% | Reduce -24.0% | 56,023 | $2.4M |
| Aquatic Capital Management LLC | 0.07% | New | 55,240 | $2.3M |
| Fred Alger Management, LLC | 0.01% | Reduce -41.2% | 54,020 | $2.3M |
| Cambridge Investment Research Advisors, Inc. | 0.01% | Add +15.2% | 53,713 | $2.3M |
| Jump Financial, LLC | 0.03% | New | 53,212 | $2.2M |
| Act Capital Management, LLC | 1.75% | — | 51,200 | $2.2M |
| Norges Bank | 0.00% | — | 50,000 | $2.1M |
| Dark Forest Capital Management LP | 0.08% | Add +360.3% | 42,277 | $1.8M |
| Headlands Technologies LLC | 0.15% | Add +38.1% | 41,201 | $1.7M |
| AWM Investment Company, Inc. | 0.16% | No change | 40,000 | $1.7M |
| Deuterium Capital Management, LLC | 2.29% | No change | 37,349 | $1.6M |
| Engineers Gate Manager LP | 0.02% | Add +111.5% | 37,284 | $1.6M |
| Citigroup Inc. | 0.00% | Add +1074.2% | 35,777 | $1.5M |
| Caption Management, LLC | 0.07% | New | 35,000 | $1.5M |
| Swiss National Bank | 0.00% | New | 31,900 | $1.3M |
| SummitTX Capital, L.P. | 0.04% | Add +361.2% | 31,353 | $1.3M |
| Birchview Capital, LP | 0.77% | Add +671.0% | 31,000 | $1.3M |
| Erste Asset Management GmbH | 0.01% | Add +64.7% | 28,000 | $1.2M |
| Simplify Asset Management Inc. | 0.02% | Reduce -67.9% | 28,000 | $1.2M |
| KVP Capital Advisors, LP | 1.17% | — | 26,900 | $1.1M |
| Fox Run Management, L.L.C. | 0.17% | New | 26,522 | $1.1M |
| Bank of America Corp. | 0.00% | Reduce -45.6% | 26,092 | $1.1M |
| Marshall Wace, LLP | 0.00% | New | 24,023 | $1.0M |
| Gsa Capital Partners LLP | 0.08% | New | 23,114 | $977K |
| Simplex Trading, LLC | 0.03% | Reduce -71.3% | 21,936 | $927K |
| BIT Capital GmbH | 0.04% | New | 21,100 | $892K |
| Squarepoint Ops LLC | 0.00% | Reduce -41.3% | 20,257 | $856K |
| Ishara Investments LP | 0.98% | — | 20,000 | $846K |
| Trexquant Investment LP | 0.01% | Reduce -79.4% | 18,821 | $796K |
| J. Goldman & Co LP | 0.03% | New | 18,352 | $776K |
| Jain Global LLC | 0.01% | Reduce -47.2% | 17,299 | $731K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | New | 16,184 | $684K |
| Susquehanna Portfolio Strategies, LLC | 0.01% | No change | 16,057 | $679K |
| Knott David M Jr | 0.30% | New | 15,500 | $655K |
| Barclays PLC | 0.00% | Reduce -7.4% | 15,444 | $653K |
| Algert Global LLC | 0.01% | New | 15,310 | $647K |
| Seven Fleet Capital Management LP | 0.43% | — | 15,000 | $634K |
| Palumbo Wealth Management LLC | 0.15% | Reduce -43.7% | 14,714 | $622K |
| Jacobs Levy Equity Management, Inc. | 0.00% | Reduce -2.6% | 14,564 | $616K |
| California State Teachers Retirement System | 0.00% | New | 14,520 | $614K |
| Virtu Financial LLC | 0.02% | New | 13,811 | $584K |
| Gainplan LLC | 0.21% | Add +168.1% | 13,500 | $571K |
| Sectoral Asset Management Inc. | 0.46% | New | 13,485 | $570K |
| Cibc World Market Inc. | 0.00% | New | 13,282 | $562K |
| Informed Momentum Co LLC | 0.06% | Reduce -83.4% | 12,972 | $548K |
| Legal & General Group Plc | 0.00% | New | 12,413 | $525K |
| HighVista Strategies LLC | 0.13% | New | 11,749 | $497K |
| SG Americas Securities, LLC | 0.00% | New | 10,954 | $463K |
| Y-Intercept (Hong Kong) Ltd | 0.01% | New | 10,862 | $459K |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -13.4% | 10,376 | $439K |
| Sei Investments Co. | 0.00% | Reduce -25.1% | 10,292 | $435K |
| Iridian Asset Management LLC | 0.15% | New | 9,728 | $411K |
| HB Wealth Management, LLC | 0.00% | No change | 9,244 | $391K |
| Sigma Planning Corp | 0.01% | New | 9,000 | $381K |
| State of Wisconsin Investment Board | 0.00% | New | 8,629 | $365K |
| Glenmede Trust Co. NA | 0.00% | — | 8,590 | $363K |
| Janus Henderson Group PLC | 0.00% | New | 8,100 | $342K |
| Leonteq Securities AG | 0.02% | New | 8,000 | $338K |
| WINTON GROUP Ltd | 0.01% | New | 7,765 | $328K |
| OMERS ADMINISTRATION Corp | 0.00% | New | 7,200 | $304K |
| XTX Topco Ltd | 0.01% | Add +22.0% | 7,196 | $304K |
| Verition Fund Management LLC | 0.00% | Reduce -71.2% | 7,035 | $297K |
| Royal Bank of Canada | 0.00% | Reduce -82.2% | 7,005 | $296K |
| Tower Research Capital LLC (TRC) | 0.01% | Add +1070.7% | 5,561 | $235K |
| FORA Capital, LLC | 0.03% | New | 5,761 | $232K |
| Osaic Holdings, Inc. | 0.00% | Reduce -0.7% | 5,388 | $228K |
| Envestnet Asset Management Inc. | 0.00% | Reduce -46.6% | 5,384 | $228K |
| Opal Capital LLC | 0.06% | — | 5,948 | $220K |
| FNY Investment Advisers, LLC | 0.06% | Add +99.8% | 5,200 | $219K |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 0.03% | New | 4,927 | $208K |
| Virtus Investment Advisers, LLC | 0.06% | New | 4,863 | $206K |
| KLP Kapitalforvaltning As | 0.00% | New | 3,500 | $148K |
| Bayforest Capital Ltd | 0.08% | Add +51.3% | 2,541 | $107K |
| Flagship Harbor Advisors, LLC | 0.00% | New | 2,179 | $92K |
| Quarry LP | 0.01% | New | 2,000 | $85K |
| Bessemer Group Inc. | 0.00% | Add +1.0% | 1,580 | $66K |
| Group One Trading LLC | 0.00% | Reduce -83.0% | 1,448 | $61K |
| US Bancorp \de | 0.00% | Reduce -30.4% | 1,260 | $53K |
| Natixis | 0.00% | New | 685 | $29K |
| Allworth Financial LP | 0.00% | No change | 676 | $29K |
| Canada Pension Plan Investment Board | 0.00% | New | 400 | $17K |
| Steward Partners Investment Advisory, LLC | 0.00% | No change | 213 | $9K |
| Cwm, LLC | 0.00% | Reduce -15.6% | 205 | $9K |
| Founders Capital Management | 0.00% | New | 200 | $8K |
| Activest Wealth Management | 0.00% | No change | 200 | $8K |
| Wells Fargo & Company | 0.00% | Reduce -23.0% | 191 | $8K |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | New | 178 | $8K |
| Los Angeles Capital Management LLC | 0.00% | New | 127 | $8K |
| SBI Securities Co., Ltd. | 0.00% | Reduce -6.4% | 146 | $6K |
| Jones Financial Companies LLLP | 0.00% | Reduce -5.2% | 109 | $5K |
| Rhumbline Advisers | 0.00% | No change | 100 | $4K |
| CIBC Private Wealth Group LLC | 0.00% | No change | 100 | $4K |
| EFG International AG | 0.00% | — | 75 | $3K |
| Signaturefd, LLC | 0.00% | Reduce -73.1% | 70 | $3K |
| Keating Financial Advisory Services, Inc. | 0.00% | — | 69 | $3K |
| MTM Investment Management, LLC | 0.00% | No change | 66 | $3K |
| Brown Brothers Harriman & Co. | 0.00% | No change | 66 | $3K |
| SJS Investment Consulting Inc. | 0.00% | New | 58 | $2K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | Reduce -29.7% | 45 | $2K |
| Atlas Capital Advisors Inc. | 0.00% | — | 40 | $2K |
| Boreal Capital Management LLC | 0.00% | No change | 36 | $2K |
| Rachor Investment Advisory Services, LLC | 0.00% | — | 35 | $1K |
| Global Retirement Partners, LLC | 0.00% | No change | 27 | $1K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -20.0% | 20 | $846 |
| ORG Partners LLC | 0.00% | No change | 20 | $845 |
| Ameriflex Group, Inc. | 0.00% | Reduce -50.0% | 13 | $550 |
| Medallion Wealth Advisors, LLC | 0.00% | No change | 13 | $550 |
| Kimelman & Baird, LLC | 0.00% | No change | 13 | $550 |
| Arlington Trust Co LLC | 0.00% | No change | 6 | $254 |
| Danske Bank A/S | 0.00% | No change | 2 | $85 |
| Arax Advisory Partners | 0.00% | Reduce -77.8% | 2 | $85 |
| Smartleaf Asset Management LLC | 0.00% | New | 2 | $84 |
| Amalgamated Bank | 0.00% | No change | 1 | $0 |
"% of holder's portfolio" is NKTR's weight in each manager's 13F, not the share of Nektar Therapeutics the manager owns.