Protalix BiotherapeuticsPLX

13F holders, Q1 2025 (March 31)
63holders +18
23new positions
5sold out
3famous investors
$2.56avg. 13F price*

At the end of Q1 2025, 63 institutions reported holding Protalix Biotherapeutics Inc. (PLX) in their 13F filings, up 18 from Q4 2024. 23 opened new positions and 5 sold out. The largest holders were Renaissance Technologies ($3.0M), Millennium Management ($2.5M) and Susquehanna International Group, LLP ($2.2M). 3 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).

Company
Protalix Biotherapeutics Inc.
CUSIP
74365A309
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150 Q1 2024: 63Q1 2024Q2 2024: 66Q2 2024Q3 2024: 45Q3 2024Q4 2024: 45Q4 2024Q1 2025: 63Q1 2025Q2 2025: 63Q2 2025Q3 2025: 77Q3 2025Q4 2025: 83Q4 2025Q1 2026: 100Q1 2026Q2 2026: 101Q2 2026

Total Exit/New Position Q4 2024 → Q1 2025

InstitutionsTotal Value
New Positions23$6.1M
Exits5$140K

All 13F filers, Q4 2024 → Q1 2025: 4,313,115 shares bought and 522,360 shares sold, net +3,790,755 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 63 holders

Renaissance Technologies 0.00% Add +6.3% 1,188,953 $3.0M
Millennium Management 0.00% Add +148.3% 963,011 $2.5M
Susquehanna International Group, LLP 0.00% New 858,650 $2.2M
Northern Trust Corp. 0.00% Reduce -6.4% 684,758 $1.8M
Marshall Wace, LLP 0.00% Add +503.6% 615,085 $1.6M
Connor, Clark & Lunn Investment Management Ltd. 0.01% New 482,875 $1.2M
Stratos Wealth Partners, LTD. 0.01% Add +28.3% 346,400 $887K
Jane Street Group, LLC 0.00% Add +159.1% 294,318 $753K
Goldman Sachs Group Inc. 0.00% Add +482.3% 289,461 $741K
BlackRock, Inc. 0.00% Add +13.3% 254,535 $652K
Gsa Capital Partners LLP 0.05% Reduce -31.6% 209,292 $536K
Bridgeway Capital Management, LLC 0.01% Add +4.2% 189,100 $484K
OMERS ADMINISTRATION Corp 0.00% New 179,300 $459K
Schonfeld Strategic Advisors LLC 0.00% New 163,058 $417K
Squarepoint Ops LLC 0.00% Add +63.4% 120,786 $309K
Qube Research & Technologies Ltd 0.00% Add +377.8% 118,808 $304K
Hillsdale Investment Management Inc. 0.02% New 116,100 $297K
Two Sigma Investments, LP 0.00% New 86,354 $221K
Morgan Stanley 0.00% Reduce -50.9% 83,558 $214K
Jain Global LLC 0.00% New 81,963 $210K
Balyasny Asset Management L.P. 0.00% New 76,063 $195K
Point72 Asia (Singapore) Pte. Ltd. 0.04% Add +1.3% 54,174 $139K
Cubist Systematic Strategies, LLC 0.00% Add +82.1% 53,380 $137K
Quantessence Capital LLC 0.03% New 51,243 $131K
Commonwealth Equity Services, LLC 0.00% Add +0.1% 50,025 $128K
Orin Green Financial, LLC 0.06% New 50,000 $128K
LMR Partners LLP 0.00% New 49,025 $126K
Kestra Advisory Services, LLC 0.00% Add +217.9% 44,500 $114K
XTX Topco Ltd 0.01% New 41,826 $107K
Prudential Financial Inc. 0.00% No change 36,400 $93K
Two Sigma Advisers, LP 0.00% New 33,015 $85K
Creative Planning 0.00% New 32,740 $84K
Catalyst Funds Management Pty Ltd 0.02% Add +166.1% 27,139 $69K
Earned Wealth Advisors, LLC 0.01% No change 25,976 $66K
HSBC Holdings PLC 0.00% Reduce -36.2% 25,535 $64K
Barclays PLC 0.00% Reduce -29.2% 24,310 $62K
Aptus Capital Advisors, LLC 0.00% Add +2.5% 23,938 $61K
Capula Management Ltd 0.00% New 15,690 $40K
Lido Advisors, LLC 0.00% No change 15,554 $40K
Capstone Investment Advisors, LLC 0.00% New 15,336 $39K
Raymond James Financial Inc. 0.00% New 15,174 $39K
NewEdge Advisors, LLC 0.00% New 15,080 $39K
Brevan Howard Capital Management LP 0.00% New 13,474 $34K
Altshuler Shaham Ltd 0.00% No change 12,142 $31K
Hudson Bay Capital Management LP 0.00% New 12,000 $31K
Harbour Investment Management LLC 0.01% No change 10,100 $26K
Acadian Asset Management LLC 0.00% New 9,691 $24K
TD Waterhouse Canada Inc. 0.00% No change 6,000 $15K
Point72 (DIFC) Ltd 0.00% Add +524.1% 5,623 $14K
Citadel Advisors 0.00% Reduce -98.1% 2,818 $7K
Truvestments Capital LLC 0.00% No change 2,458 $6K
Citigroup Inc. 0.00% Add +262.7% 2,292 $6K
UBS Group AG 0.00% Reduce -88.5% 2,087 $5K
JPMorgan Chase & Co. 0.00% No change 1,595 $4K
Lazard Asset Management LLC 0.00% Reduce -36.5% 797 $2K
BNP Paribas Financial Markets 0.00% Reduce -2.1% 701 $2K
Investment Research & Advisory Group, Inc. 0.00% New 600 $2K
Osaic Holdings, Inc. 0.00% Add +100.0% 400 $1K
Activest Wealth Management 0.00% No change 300 $768
Federation des caisses Desjardins du Quebec 0.00% No change 250 $640
Y.D. More Investments Ltd 0.00% No change 220 $563
SBI Securities Co., Ltd. 0.00% New 50 $128
Bank of America Corp. 0.00% Reduce -100.0% 6 $16

"% of holder's portfolio" is PLX's weight in each manager's 13F, not the share of Protalix Biotherapeutics Inc. the manager owns.