Protalix BiotherapeuticsPLX
13F holders, Q1 2025 (March 31)At the end of Q1 2025, 63 institutions reported holding Protalix Biotherapeutics Inc. (PLX) in their 13F filings, up 18 from Q4 2024. 23 opened new positions and 5 sold out. The largest holders were Renaissance Technologies ($3.0M), Millennium Management ($2.5M) and Susquehanna International Group, LLP ($2.2M). 3 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Protalix Biotherapeutics Inc.
- CUSIP
- 74365A309
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 23 | $6.1M |
| Exits | 5 | $140K |
All 13F filers, Q4 2024 → Q1 2025: 4,313,115 shares bought and 522,360 shares sold, net +3,790,755 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 63 holders
| Renaissance Technologies | 0.00% | Add +6.3% | 1,188,953 | $3.0M |
| Millennium Management | 0.00% | Add +148.3% | 963,011 | $2.5M |
| Susquehanna International Group, LLP | 0.00% | New | 858,650 | $2.2M |
| Northern Trust Corp. | 0.00% | Reduce -6.4% | 684,758 | $1.8M |
| Marshall Wace, LLP | 0.00% | Add +503.6% | 615,085 | $1.6M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.01% | New | 482,875 | $1.2M |
| Stratos Wealth Partners, LTD. | 0.01% | Add +28.3% | 346,400 | $887K |
| Jane Street Group, LLC | 0.00% | Add +159.1% | 294,318 | $753K |
| Goldman Sachs Group Inc. | 0.00% | Add +482.3% | 289,461 | $741K |
| BlackRock, Inc. | 0.00% | Add +13.3% | 254,535 | $652K |
| Gsa Capital Partners LLP | 0.05% | Reduce -31.6% | 209,292 | $536K |
| Bridgeway Capital Management, LLC | 0.01% | Add +4.2% | 189,100 | $484K |
| OMERS ADMINISTRATION Corp | 0.00% | New | 179,300 | $459K |
| Schonfeld Strategic Advisors LLC | 0.00% | New | 163,058 | $417K |
| Squarepoint Ops LLC | 0.00% | Add +63.4% | 120,786 | $309K |
| Qube Research & Technologies Ltd | 0.00% | Add +377.8% | 118,808 | $304K |
| Hillsdale Investment Management Inc. | 0.02% | New | 116,100 | $297K |
| Two Sigma Investments, LP | 0.00% | New | 86,354 | $221K |
| Morgan Stanley | 0.00% | Reduce -50.9% | 83,558 | $214K |
| Jain Global LLC | 0.00% | New | 81,963 | $210K |
| Balyasny Asset Management L.P. | 0.00% | New | 76,063 | $195K |
| Point72 Asia (Singapore) Pte. Ltd. | 0.04% | Add +1.3% | 54,174 | $139K |
| Cubist Systematic Strategies, LLC | 0.00% | Add +82.1% | 53,380 | $137K |
| Quantessence Capital LLC | 0.03% | New | 51,243 | $131K |
| Commonwealth Equity Services, LLC | 0.00% | Add +0.1% | 50,025 | $128K |
| Orin Green Financial, LLC | 0.06% | New | 50,000 | $128K |
| LMR Partners LLP | 0.00% | New | 49,025 | $126K |
| Kestra Advisory Services, LLC | 0.00% | Add +217.9% | 44,500 | $114K |
| XTX Topco Ltd | 0.01% | New | 41,826 | $107K |
| Prudential Financial Inc. | 0.00% | No change | 36,400 | $93K |
| Two Sigma Advisers, LP | 0.00% | New | 33,015 | $85K |
| Creative Planning | 0.00% | New | 32,740 | $84K |
| Catalyst Funds Management Pty Ltd | 0.02% | Add +166.1% | 27,139 | $69K |
| Earned Wealth Advisors, LLC | 0.01% | No change | 25,976 | $66K |
| HSBC Holdings PLC | 0.00% | Reduce -36.2% | 25,535 | $64K |
| Barclays PLC | 0.00% | Reduce -29.2% | 24,310 | $62K |
| Aptus Capital Advisors, LLC | 0.00% | Add +2.5% | 23,938 | $61K |
| Capula Management Ltd | 0.00% | New | 15,690 | $40K |
| Lido Advisors, LLC | 0.00% | No change | 15,554 | $40K |
| Capstone Investment Advisors, LLC | 0.00% | New | 15,336 | $39K |
| Raymond James Financial Inc. | 0.00% | New | 15,174 | $39K |
| NewEdge Advisors, LLC | 0.00% | New | 15,080 | $39K |
| Brevan Howard Capital Management LP | 0.00% | New | 13,474 | $34K |
| Altshuler Shaham Ltd | 0.00% | No change | 12,142 | $31K |
| Hudson Bay Capital Management LP | 0.00% | New | 12,000 | $31K |
| Harbour Investment Management LLC | 0.01% | No change | 10,100 | $26K |
| Acadian Asset Management LLC | 0.00% | New | 9,691 | $24K |
| TD Waterhouse Canada Inc. | 0.00% | No change | 6,000 | $15K |
| Point72 (DIFC) Ltd | 0.00% | Add +524.1% | 5,623 | $14K |
| Citadel Advisors | 0.00% | Reduce -98.1% | 2,818 | $7K |
| Truvestments Capital LLC | 0.00% | No change | 2,458 | $6K |
| Citigroup Inc. | 0.00% | Add +262.7% | 2,292 | $6K |
| UBS Group AG | 0.00% | Reduce -88.5% | 2,087 | $5K |
| JPMorgan Chase & Co. | 0.00% | No change | 1,595 | $4K |
| Lazard Asset Management LLC | 0.00% | Reduce -36.5% | 797 | $2K |
| BNP Paribas Financial Markets | 0.00% | Reduce -2.1% | 701 | $2K |
| Investment Research & Advisory Group, Inc. | 0.00% | New | 600 | $2K |
| Osaic Holdings, Inc. | 0.00% | Add +100.0% | 400 | $1K |
| Activest Wealth Management | 0.00% | No change | 300 | $768 |
| Federation des caisses Desjardins du Quebec | 0.00% | No change | 250 | $640 |
| Y.D. More Investments Ltd | 0.00% | No change | 220 | $563 |
| SBI Securities Co., Ltd. | 0.00% | New | 50 | $128 |
| Bank of America Corp. | 0.00% | Reduce -100.0% | 6 | $16 |
"% of holder's portfolio" is PLX's weight in each manager's 13F, not the share of Protalix Biotherapeutics Inc. the manager owns.