Protalix BiotherapeuticsPLX
13F holders, Q3 2025 (September 30)77holders +14
17new positions
3sold out
2famous investors
$2.22avg. 13F price*
At the end of Q3 2025, 77 institutions reported holding Protalix Biotherapeutics Inc. (PLX) in their 13F filings, up 14 from Q2 2025. 17 opened new positions and 3 sold out. The largest holders were BlackRock, Inc. ($7.9M), Opaleye Management Inc. ($5.7M) and Renaissance Technologies ($2.9M). 2 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Protalix Biotherapeutics Inc.
- CUSIP
- 74365A309
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 17 | $6.5M |
| Exits | 3 | $321K |
All 13F filers, Q2 2025 → Q3 2025: 3,605,944 shares bought and 1,587,252 shares sold, net +2,018,692 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 77 holders
| BlackRock, Inc. | 0.00% | Add +5.4% | 3,551,028 | $7.9M |
| Opaleye Management Inc. | 0.82% | New | 2,580,556 | $5.7M |
| Renaissance Technologies | 0.00% | Reduce -18.6% | 1,315,400 | $2.9M |
| Northern Trust Corp. | 0.00% | Reduce -16.4% | 902,459 | $2.0M |
| Geode Capital Management, LLC | 0.00% | Reduce -0.8% | 819,777 | $1.8M |
| Stratos Wealth Partners, LTD. | 0.01% | Add +42.9% | 500,000 | $1.1M |
| State Street Corp. | 0.00% | Add +12.2% | 498,547 | $1.1M |
| Vanguard Group Inc. | 0.00% | Reduce -4.2% | 464,421 | $1.0M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.00% | Reduce -19.3% | 400,398 | $889K |
| UBS Group AG | 0.00% | Add +153.2% | 190,276 | $422K |
| Bridgeway Capital Management, LLC | 0.01% | No change | 189,100 | $420K |
| Diametric Capital, LP | 0.15% | Add +25.6% | 179,984 | $400K |
| Charles Schwab Investment Management Inc. | 0.00% | No change | 175,070 | $389K |
| Commonwealth Equity Services, LLC | 0.00% | Reduce -12.7% | 171,772 | $381K |
| Evergreen Capital Management LLC | 0.01% | No change | 171,338 | $380K |
| Goldman Sachs Group Inc. | 0.00% | Add +47.6% | 150,829 | $335K |
| Bank of New York Mellon Corp | 0.00% | Add +3.2% | 138,548 | $308K |
| Main Street Financial Solutions, LLC | 0.02% | New | 129,100 | $287K |
| Barclays PLC | 0.00% | Reduce -19.8% | 101,798 | $226K |
| Nuveen, LLC | 0.00% | No change | 90,188 | $200K |
| XTX Topco Ltd | 0.01% | Add +16.5% | 85,841 | $191K |
| Susquehanna International Group, LLP | 0.00% | Reduce -75.6% | 72,922 | $162K |
| Morgan Stanley | 0.00% | Reduce -84.6% | 71,037 | $158K |
| Wolverine Trading, LLC | 0.00% | Add +187.2% | 70,394 | $152K |
| Deutsche Bank AG | 0.00% | New | 65,617 | $146K |
| Rhumbline Advisers | 0.00% | Reduce -6.6% | 65,194 | $145K |
| Orin Green Financial, LLC | 0.05% | No change | 61,200 | $136K |
| Prelude Capital Management, LLC | 0.01% | Reduce -11.2% | 49,791 | $111K |
| Invesco Ltd. | 0.00% | Reduce -0.3% | 45,003 | $100K |
| Wells Fargo & Company | 0.00% | Add +18.9% | 42,831 | $95K |
| New York State Common Retirement Fund | 0.00% | Reduce -40.1% | 41,300 | $92K |
| State of Wyoming | 0.01% | New | 39,018 | $87K |
| Citadel Advisors | 0.00% | New | 37,306 | $83K |
| T. Rowe Price Associates Inc. | 0.00% | No change | 35,278 | $79K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -15.3% | 32,253 | $72K |
| Intech Investment Management LLC | 0.00% | Reduce -14.4% | 31,248 | $69K |
| JPMorgan Chase & Co. | 0.00% | Reduce -13.2% | 29,991 | $67K |
| Earned Wealth Advisors, LLC | 0.01% | Reduce 0.0% | 25,975 | $58K |
| Aptus Capital Advisors, LLC | 0.00% | Add +3.5% | 25,727 | $57K |
| Manufacturers Life Insurance Company, The | 0.00% | New | 24,054 | $53K |
| Bank of America Corp. | 0.00% | Reduce -8.1% | 20,119 | $45K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 18,554 | $41K |
| Cascade Financial Partners, LLC | 0.00% | No change | 17,000 | $38K |
| Dimensional Fund Advisors LP | 0.00% | Reduce -62.6% | 17,028 | $38K |
| Virtu Financial LLC | 0.00% | New | 16,530 | $37K |
| Lido Advisors, LLC | 0.00% | No change | 15,554 | $35K |
| BNP Paribas Financial Markets | 0.00% | Add +126.5% | 15,215 | $34K |
| Altshuler Shaham Ltd | 0.00% | No change | 12,142 | $27K |
| ProShare Advisors LLC | 0.00% | Reduce -16.6% | 11,922 | $26K |
| Alliancebernstein L.P. | 0.00% | No change | 11,720 | $26K |
| Kestra Advisory Services, LLC | 0.00% | New | 11,000 | $24K |
| Two Sigma Advisers, LP | 0.00% | New | 10,300 | $23K |
| LPL Financial LLC | 0.00% | New | 10,291 | $23K |
| Harbour Investment Management LLC | 0.01% | No change | 10,100 | $22K |
| Legal & General Group Plc | 0.00% | No change | 7,757 | $17K |
| Russell Investments Group, Ltd. | 0.00% | New | 7,465 | $17K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 7,119 | $16K |
| Citigroup Inc. | 0.00% | Reduce -73.3% | 6,614 | $15K |
| TD Waterhouse Canada Inc. | 0.00% | No change | 6,000 | $14K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +4240.9% | 5,513 | $12K |
| California State Teachers Retirement System | 0.00% | Add +0.1% | 4,353 | $10K |
| Simplex Trading, LLC | 0.00% | New | 2,942 | $6K |
| Truvestments Capital LLC | 0.00% | No change | 2,458 | $5K |
| Amalgamated Bank | 0.00% | No change | 2,381 | $5K |
| Investment Research & Advisory Group, Inc. | 0.00% | No change | 1,000 | $2K |
| Royal Bank of Canada | 0.00% | Add +266.2% | 1,073 | $2K |
| Osaic Holdings, Inc. | 0.00% | No change | 700 | $1K |
| FMR LLC | 0.00% | New | 438 | $972 |
| Activest Wealth Management | 0.00% | No change | 300 | $666 |
| Arax Advisory Partners | 0.00% | New | 296 | $658 |
| Federation des caisses Desjardins du Quebec | 0.00% | No change | 250 | $555 |
| Y.D. More Investments Ltd | 0.00% | No change | 220 | $488 |
| SBI Securities Co., Ltd. | 0.00% | Add +0.5% | 201 | $446 |
| Sterling Capital Management LLC | 0.00% | Add +0.6% | 169 | $375 |
| PNC Financial Services Group, Inc. | 0.00% | New | 35 | $78 |
| Steward Partners Investment Advisory, LLC | 0.00% | New | 25 | $56 |
| Cwm, LLC | 0.00% | New | 163 | $0 |
"% of holder's portfolio" is PLX's weight in each manager's 13F, not the share of Protalix Biotherapeutics Inc. the manager owns.