Prothena Corp.PRTA
13F holders, Q4 2024 (December 31)At the end of Q4 2024, 170 institutions reported holding Prothena Corp. PLC (PRTA) in their 13F filings, up 6 from Q3 2024. 23 opened new positions and 27 sold out. The largest holders were EcoR1 Capital, LLC ($160.4M), FMR LLC ($111.8M) and Wellington Management Group LLP ($71.1M). 4 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Prothena Corp. PLC
- CUSIP
- G72800108
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2024 → Q4 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 23 | $5.4M |
| Exits | 27 | $16.7M |
All 13F filers, Q3 2024 → Q4 2024: 4,195,466 shares bought and 1,797,980 shares sold, net +2,397,486 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 170 holders
| EcoR1 Capital, LLC | 6.42% | No change | 11,584,280 | $160.4M |
| FMR LLC | 0.01% | Add +0.1% | 8,071,309 | $111.8M |
| Wellington Management Group LLP | 0.01% | Add +22.8% | 5,130,876 | $71.1M |
| BlackRock, Inc. | 0.00% | Add +2.3% | 4,122,376 | $57.1M |
| T. Rowe Price Associates Inc. | 0.01% | Reduce -3.6% | 3,685,708 | $51.0M |
| Armistice Capital, LLC | 0.72% | Add +35.5% | 2,236,000 | $31.0M |
| State Street Corp. | 0.00% | Add +11.2% | 1,861,641 | $25.8M |
| Palo Alto Investors LP | 3.73% | No change | 1,737,964 | $24.1M |
| Vanguard Group Inc. | 0.00% | Add +11.5% | 1,403,838 | $19.4M |
| Siren, L.L.C. | 0.67% | No change | 1,099,840 | $15.2M |
| Geode Capital Management, LLC | 0.00% | Add +0.1% | 964,308 | $13.4M |
| Dimensional Fund Advisors LP | 0.00% | Add +1.3% | 864,833 | $12.0M |
| Federated Hermes, Inc. | 0.02% | Add +84.3% | 746,177 | $10.3M |
| Morgan Stanley | 0.00% | Add +0.0% | 719,490 | $10.0M |
| Boxer Capital Management, LLC | 0.81% | — | 690,000 | $9.6M |
| Finepoint Capital LP | 1.05% | Add +51.6% | 657,071 | $9.1M |
| Rock Springs Capital Management LP | 0.34% | Add +3.1% | 644,601 | $8.9M |
| Goldman Sachs Group Inc. | 0.00% | Add +34.0% | 556,526 | $7.7M |
| Prosight Management, LP | 1.62% | Reduce -13.5% | 418,122 | $5.8M |
| Northern Trust Corp. | 0.00% | Add +8.5% | 404,496 | $5.6M |
| JPMorgan Chase & Co. | 0.00% | Add +93.7% | 387,350 | $5.4M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -27.6% | 381,508 | $5.3M |
| UBS Group AG | 0.00% | Add +494.0% | 371,287 | $5.1M |
| Mariner, LLC | 0.01% | Add +6.4% | 343,917 | $4.8M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +0.7% | 327,151 | $4.5M |
| Birchview Capital, LP | 3.43% | Add +45.3% | 304,574 | $4.2M |
| Renaissance Technologies | 0.00% | Add +10.4% | 201,900 | $2.8M |
| Nuveen Asset Management, LLC | 0.00% | Add +0.3% | 152,107 | $2.1M |
| Bank of New York Mellon Corp | 0.00% | Add +14.9% | 150,238 | $2.1M |
| PDT Partners, LLC | 0.16% | Add +15.0% | 127,203 | $1.8M |
| Millennium Management | 0.00% | Add +9.3% | 123,005 | $1.7M |
| AXA S.A. | 0.01% | Reduce -0.1% | 120,630 | $1.7M |
| Bank of America Corp. | 0.00% | Add +45.0% | 119,007 | $1.6M |
| Barclays PLC | 0.00% | Add +10.6% | 105,338 | $1.5M |
| DCF Advisers, LLC | 0.73% | Reduce -3.7% | 103,500 | $1.4M |
| Pinnacle Associates Ltd. | 0.02% | Reduce -18.0% | 103,081 | $1.4M |
| BNP Paribas Financial Markets | 0.00% | Add +74.4% | 97,383 | $1.3M |
| Deutsche Bank AG | 0.00% | Add +195.7% | 95,970 | $1.3M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.01% | Reduce -25.0% | 91,840 | $1.3M |
| Susquehanna Fundamental Investments, LLC | 0.02% | — | 80,677 | $1.1M |
| Rafferty Asset Management, LLC | 0.00% | Add +24.8% | 77,672 | $1.1M |
| Man Group plc | 0.00% | Add +90.7% | 77,430 | $1.1M |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -18.5% | 70,184 | $972K |
| Duncan Williams Asset Management, LLC | 0.38% | Add +42.0% | 69,199 | $958K |
| Swiss National Bank | 0.00% | No change | 68,700 | $951K |
| Citigroup Inc. | 0.00% | Add +113.4% | 68,433 | $948K |
| Rhumbline Advisers | 0.00% | Add +1.8% | 67,115 | $930K |
| TD Asset Management Inc | 0.00% | Reduce -35.8% | 64,694 | $896K |
| Boothbay Fund Management, LLC | 0.03% | New | 62,002 | $859K |
| Norges Bank | 0.00% | No change | 57,454 | $796K |
| Jane Street Group, LLC | 0.00% | Reduce -41.8% | 55,528 | $769K |
| Wells Fargo & Company | 0.00% | Reduce -20.2% | 52,823 | $732K |
| Hennion & Walsh Asset Management, Inc. | 0.03% | New | 52,284 | $724K |
| Alliancebernstein L.P. | 0.00% | Add +0.0% | 46,753 | $648K |
| Massachusetts Financial Services Co. | 0.00% | New | 44,815 | $621K |
| Alps Advisors Inc. | 0.00% | Add +4.5% | 43,510 | $603K |
| Invesco Ltd. | 0.00% | Add +4.0% | 42,846 | $593K |
| Citadel Advisors | 0.00% | Reduce -82.5% | 41,518 | $575K |
| Legal & General Group Plc | 0.00% | Add +2.9% | 41,405 | $573K |
| Verition Fund Management LLC | 0.00% | New | 39,422 | $546K |
| Thrivent Financial for Lutherans | 0.00% | Reduce -18.7% | 38,626 | $535K |
| Two Sigma Investments, LP | 0.00% | Add +265.4% | 38,394 | $532K |
| Balyasny Asset Management L.P. | 0.00% | New | 38,021 | $527K |
| SG Americas Securities, LLC | 0.00% | Add +167.0% | 37,612 | $521K |
| California State Teachers Retirement System | 0.00% | Reduce -0.9% | 33,243 | $460K |
| Focused Wealth Management, Inc | 0.06% | New | 32,129 | $445K |
| American Century Companies Inc. | 0.00% | Add +66.1% | 30,399 | $421K |
| RBF Capital, LLC | 0.02% | Reduce -35.6% | 29,200 | $404K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +6.0% | 27,269 | $381K |
| Tudor Investment Corporation | 0.00% | Reduce -0.5% | 27,398 | $379K |
| MetLife Investment Management, LLC | 0.00% | Add +2.1% | 25,873 | $358K |
| Susquehanna International Group, LLP | 0.00% | Reduce -46.7% | 25,269 | $350K |
| Edgewood Management LLC | 0.00% | No change | 24,060 | $333K |
| Caption Management, LLC | 0.01% | New | 24,000 | $332K |
| HSBC Holdings PLC | 0.00% | Add +60.4% | 24,179 | $323K |
| Intech Investment Management LLC | 0.00% | Add +78.3% | 22,383 | $310K |
| Ensign Peak Advisors, Inc | 0.00% | No change | 21,643 | $300K |
| Corebridge Financial, Inc. | 0.00% | Reduce -7.0% | 21,140 | $293K |
| Handelsbanken Fonder AB | 0.00% | Add +35.7% | 20,900 | $289K |
| Franklin Resources Inc. | 0.00% | New | 19,687 | $273K |
| Foundation Wealth Management, LLC | 0.21% | New | 19,471 | $270K |
| Cresset Asset Management, LLC | 0.00% | Reduce -20.4% | 19,434 | $269K |
| XTX Topco Ltd | 0.02% | Add +19.9% | 18,665 | $259K |
| Janus Henderson Group PLC | 0.00% | No change | 18,047 | $249K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +208.3% | 16,826 | $233K |
| Schroder Investment Management Group | 0.00% | No change | 15,000 | $223K |
| Creative Planning | 0.00% | Reduce -23.2% | 16,061 | $222K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +56.6% | 16,030 | $222K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 15,386 | $213K |
| Profund Advisors LLC | 0.01% | Add +20.1% | 15,212 | $211K |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 14,000 | $208K |
| Walleye Capital LLC | 0.00% | New | 14,953 | $207K |
| ProShare Advisors LLC | 0.00% | Add +29.5% | 14,524 | $201K |
| New York State Common Retirement Fund | 0.00% | No change | 14,279 | $198K |
| Raymond James Financial Inc. | 0.00% | — | 13,111 | $182K |
| KLP Kapitalforvaltning As | 0.00% | — | 12,900 | $179K |
| Voya Investment Management LLC | 0.00% | Reduce -8.1% | 12,829 | $178K |
| Cary Street Partners Financial LLC | 0.01% | — | 12,500 | $173K |
| Wolverine Trading, LLC | 0.00% | New | 11,162 | $166K |
| Chicago Partners Investment Group LLC | 0.01% | New | 11,197 | $159K |
| China Universal Asset Management Co., Ltd. | 0.01% | Add +10.3% | 11,409 | $158K |
| HighMark Wealth Management LLC | 0.09% | Reduce -32.3% | 11,168 | $155K |
| Purkiss Capital Advisors LLC | 0.13% | — | 10,729 | $149K |
| Teacher Retirement System of Texas | 0.00% | New | 10,434 | $145K |
| Arizona State Retirement System | 0.00% | Add +0.7% | 10,136 | $140K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | — | 10,113 | $140K |
| Headlands Technologies LLC | 0.01% | Add +196.5% | 7,330 | $102K |
| Royal Bank of Canada | 0.00% | Reduce -22.4% | 6,904 | $96K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 6,552 | $91K |
| Virtus Advisers, LLC | 0.03% | Add +19.3% | 5,148 | $71K |
| Group One Trading LLC | 0.00% | Reduce -35.1% | 4,824 | $67K |
| Acadian Asset Management LLC | 0.00% | New | 4,565 | $63K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 4,368 | $60K |
| STRS Ohio | 0.00% | Reduce -67.9% | 3,600 | $50K |
| Amundi | 0.00% | Reduce -85.7% | 1,954 | $28K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Reduce -7.8% | 1,793 | $27K |
| Amalgamated Bank | 0.00% | No change | 1,440 | $20K |
| Cwm, LLC | 0.00% | Add +118.2% | 1,189 | $16K |
| GF Fund Management Co. LTD. | 0.00% | — | 1,130 | $16K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -19.3% | 980 | $14K |
| SBI Securities Co., Ltd. | 0.00% | — | 972 | $13K |
| Russell Investments Group, Ltd. | 0.00% | Reduce -11.5% | 881 | $12K |
| US Bancorp \de | 0.00% | Add +7.8% | 861 | $12K |
| HM Payson & Co. | 0.00% | New | 800 | $11K |
| Blue Trust, Inc. | 0.00% | Add +1241.5% | 711 | $10K |
| Lindbrook Capital, LLC | 0.00% | Add +557.3% | 677 | $9K |
| Versant Capital Management, Inc | 0.00% | Add +93.5% | 629 | $9K |
| Sterling Capital Management LLC | 0.00% | Add +552.8% | 594 | $8K |
| PNC Financial Services Group, Inc. | 0.00% | Reduce -39.4% | 416 | $6K |
| Farther Finance Advisors, LLC | 0.00% | Reduce -5.9% | 353 | $5K |
| Signaturefd, LLC | 0.00% | Reduce -60.9% | 352 | $5K |
| Aster Capital Management (DIFC) Ltd | 0.00% | Reduce -18.9% | 288 | $4K |
| Osaic Holdings, Inc. | 0.00% | Reduce -69.4% | 259 | $4K |
| Manchester Capital Management LLC | 0.00% | No change | 250 | $3K |
| Daiwa Securities Group Inc. | 0.00% | No change | 195 | $3K |
| MeadowBrook Investment Advisors LLC | 0.00% | No change | 200 | $3K |
| Evelyn Partners Investment Management LLP | 0.00% | — | 199 | $3K |
| Asset Dedication, LLC | 0.00% | No change | 184 | $3K |
| Brooklyn Investment Group | 0.00% | New | 161 | $2K |
| Quadrant Capital Group LLC | 0.00% | Reduce -88.6% | 158 | $2K |
| Sittner & Nelson, LLC | 0.00% | No change | 155 | $2K |
| IFP Advisors, Inc | 0.00% | New | 132 | $2K |
| GAMMA Investing LLC | 0.00% | Add +89.5% | 127 | $2K |
| Albion Financial Group | 0.00% | No change | 125 | $2K |
| Caitong International Asset Management Co., Ltd | 0.00% | — | 115 | $2K |
| Private Wealth Management Group, LLC | 0.00% | Reduce -54.8% | 104 | $1K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +9.5% | 104 | $1K |
| Gould Capital, LLC | 0.00% | No change | 100 | $1K |
| Harbor Investment Advisory, LLC | 0.00% | No change | 100 | $1K |
| CVA Family Office, LLC | 0.00% | Reduce -23.4% | 72 | $997 |
| Parallel Advisors, LLC | 0.00% | Add +0.0% | 70 | $970 |
| Truvestments Capital LLC | 0.00% | No change | 68 | $942 |
| CIBC Private Wealth Group LLC | 0.00% | No change | 49 | $694 |
| Rothschild Investment LLC | 0.00% | Reduce -12.5% | 35 | $485 |
| Cassady Schiller Wealth Management, LLC | 0.00% | New | 34 | $471 |
| Huntington National Bank | 0.00% | New | 34 | $471 |
| Larson Financial Group LLC | 0.00% | New | 31 | $429 |
| POM Investment Strategies, LLC | 0.00% | No change | 24 | $332 |
| CoreCap Advisors, LLC | 0.00% | No change | 23 | $319 |
| Allworth Financial LP | 0.00% | Reduce -52.3% | 21 | $304 |
| MassMutual Private Wealth & Trust, FSB | 0.00% | Add +233.3% | 20 | $277 |
| Key Financial Inc | 0.00% | No change | 12 | $166 |
| Lowe Wealth Advisors, LLC | 0.00% | No change | 10 | $139 |
| Colonial Trust Advisors | 0.00% | New | 7 | $97 |
| Clearstead Advisors, LLC | 0.00% | No change | 4 | $56 |
| Valley Wealth Managers, Inc. | 0.00% | No change | 3 | $42 |
| Whittier Trust Co. of Nevada Inc. | 0.00% | No change | 3 | $41 |
| CBIZ Investment Advisory Services, LLC | 0.00% | New | 2 | $28 |
| Harbour Investments, Inc. | 0.00% | No change | 1 | $14 |
| Covestor Ltd | 0.00% | No change | 4 | $0 |
"% of holder's portfolio" is PRTA's weight in each manager's 13F, not the share of Prothena Corp. PLC the manager owns.