Prothena Corp.PRTA

13F holders, Q4 2024 (December 31)
170holders +6
23new positions
27sold out
4famous investors
$13.85avg. 13F price*

At the end of Q4 2024, 170 institutions reported holding Prothena Corp. PLC (PRTA) in their 13F filings, up 6 from Q3 2024. 23 opened new positions and 27 sold out. The largest holders were EcoR1 Capital, LLC ($160.4M), FMR LLC ($111.8M) and Wellington Management Group LLP ($71.1M). 4 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).

Company
Prothena Corp. PLC
CUSIP
G72800108
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150200 Q1 2024: 169Q1 2024Q2 2024: 160Q2 2024Q3 2024: 164Q3 2024Q4 2024: 170Q4 2024Q1 2025: 161Q1 2025Q2 2025: 188Q2 2025Q3 2025: 187Q3 2025Q4 2025: 182Q4 2025Q1 2026: 186Q1 2026Q2 2026: 187Q2 2026

Total Exit/New Position Q3 2024 → Q4 2024

InstitutionsTotal Value
New Positions23$5.4M
Exits27$16.7M

All 13F filers, Q3 2024 → Q4 2024: 4,195,466 shares bought and 1,797,980 shares sold, net +2,397,486 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 170 holders

EcoR1 Capital, LLC 6.42% No change 11,584,280 $160.4M
FMR LLC 0.01% Add +0.1% 8,071,309 $111.8M
Wellington Management Group LLP 0.01% Add +22.8% 5,130,876 $71.1M
BlackRock, Inc. 0.00% Add +2.3% 4,122,376 $57.1M
T. Rowe Price Associates Inc. 0.01% Reduce -3.6% 3,685,708 $51.0M
Armistice Capital, LLC 0.72% Add +35.5% 2,236,000 $31.0M
State Street Corp. 0.00% Add +11.2% 1,861,641 $25.8M
Palo Alto Investors LP 3.73% No change 1,737,964 $24.1M
Vanguard Group Inc. 0.00% Add +11.5% 1,403,838 $19.4M
Siren, L.L.C. 0.67% No change 1,099,840 $15.2M
Geode Capital Management, LLC 0.00% Add +0.1% 964,308 $13.4M
Dimensional Fund Advisors LP 0.00% Add +1.3% 864,833 $12.0M
Federated Hermes, Inc. 0.02% Add +84.3% 746,177 $10.3M
Morgan Stanley 0.00% Add +0.0% 719,490 $10.0M
Boxer Capital Management, LLC 0.81% — 690,000 $9.6M
Finepoint Capital LP 1.05% Add +51.6% 657,071 $9.1M
Rock Springs Capital Management LP 0.34% Add +3.1% 644,601 $8.9M
Goldman Sachs Group Inc. 0.00% Add +34.0% 556,526 $7.7M
Prosight Management, LP 1.62% Reduce -13.5% 418,122 $5.8M
Northern Trust Corp. 0.00% Add +8.5% 404,496 $5.6M
JPMorgan Chase & Co. 0.00% Add +93.7% 387,350 $5.4M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% Reduce -27.6% 381,508 $5.3M
UBS Group AG 0.00% Add +494.0% 371,287 $5.1M
Mariner, LLC 0.01% Add +6.4% 343,917 $4.8M
Charles Schwab Investment Management Inc. 0.00% Add +0.7% 327,151 $4.5M
Birchview Capital, LP 3.43% Add +45.3% 304,574 $4.2M
Renaissance Technologies 0.00% Add +10.4% 201,900 $2.8M
Nuveen Asset Management, LLC 0.00% Add +0.3% 152,107 $2.1M
Bank of New York Mellon Corp 0.00% Add +14.9% 150,238 $2.1M
PDT Partners, LLC 0.16% Add +15.0% 127,203 $1.8M
Millennium Management 0.00% Add +9.3% 123,005 $1.7M
AXA S.A. 0.01% Reduce -0.1% 120,630 $1.7M
Bank of America Corp. 0.00% Add +45.0% 119,007 $1.6M
Barclays PLC 0.00% Add +10.6% 105,338 $1.5M
DCF Advisers, LLC 0.73% Reduce -3.7% 103,500 $1.4M
Pinnacle Associates Ltd. 0.02% Reduce -18.0% 103,081 $1.4M
BNP Paribas Financial Markets 0.00% Add +74.4% 97,383 $1.3M
Deutsche Bank AG 0.00% Add +195.7% 95,970 $1.3M
Connor, Clark & Lunn Investment Management Ltd. 0.01% Reduce -25.0% 91,840 $1.3M
Susquehanna Fundamental Investments, LLC 0.02% — 80,677 $1.1M
Rafferty Asset Management, LLC 0.00% Add +24.8% 77,672 $1.1M
Man Group plc 0.00% Add +90.7% 77,430 $1.1M
Manufacturers Life Insurance Company, The 0.00% Reduce -18.5% 70,184 $972K
Duncan Williams Asset Management, LLC 0.38% Add +42.0% 69,199 $958K
Swiss National Bank 0.00% No change 68,700 $951K
Citigroup Inc. 0.00% Add +113.4% 68,433 $948K
Rhumbline Advisers 0.00% Add +1.8% 67,115 $930K
TD Asset Management Inc 0.00% Reduce -35.8% 64,694 $896K
Boothbay Fund Management, LLC 0.03% New 62,002 $859K
Norges Bank 0.00% No change 57,454 $796K
Jane Street Group, LLC 0.00% Reduce -41.8% 55,528 $769K
Wells Fargo & Company 0.00% Reduce -20.2% 52,823 $732K
Hennion & Walsh Asset Management, Inc. 0.03% New 52,284 $724K
Alliancebernstein L.P. 0.00% Add +0.0% 46,753 $648K
Massachusetts Financial Services Co. 0.00% New 44,815 $621K
Alps Advisors Inc. 0.00% Add +4.5% 43,510 $603K
Invesco Ltd. 0.00% Add +4.0% 42,846 $593K
Citadel Advisors 0.00% Reduce -82.5% 41,518 $575K
Legal & General Group Plc 0.00% Add +2.9% 41,405 $573K
Verition Fund Management LLC 0.00% New 39,422 $546K
Thrivent Financial for Lutherans 0.00% Reduce -18.7% 38,626 $535K
Two Sigma Investments, LP 0.00% Add +265.4% 38,394 $532K
Balyasny Asset Management L.P. 0.00% New 38,021 $527K
SG Americas Securities, LLC 0.00% Add +167.0% 37,612 $521K
California State Teachers Retirement System 0.00% Reduce -0.9% 33,243 $460K
Focused Wealth Management, Inc 0.06% New 32,129 $445K
American Century Companies Inc. 0.00% Add +66.1% 30,399 $421K
RBF Capital, LLC 0.02% Reduce -35.6% 29,200 $404K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Add +6.0% 27,269 $381K
Tudor Investment Corporation 0.00% Reduce -0.5% 27,398 $379K
MetLife Investment Management, LLC 0.00% Add +2.1% 25,873 $358K
Susquehanna International Group, LLP 0.00% Reduce -46.7% 25,269 $350K
Edgewood Management LLC 0.00% No change 24,060 $333K
Caption Management, LLC 0.01% New 24,000 $332K
HSBC Holdings PLC 0.00% Add +60.4% 24,179 $323K
Intech Investment Management LLC 0.00% Add +78.3% 22,383 $310K
Ensign Peak Advisors, Inc 0.00% No change 21,643 $300K
Corebridge Financial, Inc. 0.00% Reduce -7.0% 21,140 $293K
Handelsbanken Fonder AB 0.00% Add +35.7% 20,900 $289K
Franklin Resources Inc. 0.00% New 19,687 $273K
Foundation Wealth Management, LLC 0.21% New 19,471 $270K
Cresset Asset Management, LLC 0.00% Reduce -20.4% 19,434 $269K
XTX Topco Ltd 0.02% Add +19.9% 18,665 $259K
Janus Henderson Group PLC 0.00% No change 18,047 $249K
Tower Research Capital LLC (TRC) 0.00% Add +208.3% 16,826 $233K
Schroder Investment Management Group 0.00% No change 15,000 $223K
Creative Planning 0.00% Reduce -23.2% 16,061 $222K
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% Add +56.6% 16,030 $222K
State Board of Administration of Florida Retirement System 0.00% No change 15,386 $213K
Profund Advisors LLC 0.01% Add +20.1% 15,212 $211K
DekaBank Deutsche Girozentrale 0.00% No change 14,000 $208K
Walleye Capital LLC 0.00% New 14,953 $207K
ProShare Advisors LLC 0.00% Add +29.5% 14,524 $201K
New York State Common Retirement Fund 0.00% No change 14,279 $198K
Raymond James Financial Inc. 0.00% — 13,111 $182K
KLP Kapitalforvaltning As 0.00% — 12,900 $179K
Voya Investment Management LLC 0.00% Reduce -8.1% 12,829 $178K
Cary Street Partners Financial LLC 0.01% — 12,500 $173K
Wolverine Trading, LLC 0.00% New 11,162 $166K
Chicago Partners Investment Group LLC 0.01% New 11,197 $159K
China Universal Asset Management Co., Ltd. 0.01% Add +10.3% 11,409 $158K
HighMark Wealth Management LLC 0.09% Reduce -32.3% 11,168 $155K
Purkiss Capital Advisors LLC 0.13% — 10,729 $149K
Teacher Retirement System of Texas 0.00% New 10,434 $145K
Arizona State Retirement System 0.00% Add +0.7% 10,136 $140K
Police & Firemen's Retirement System of New Jersey 0.00% — 10,113 $140K
Headlands Technologies LLC 0.01% Add +196.5% 7,330 $102K
Royal Bank of Canada 0.00% Reduce -22.4% 6,904 $96K
Public Employees Retirement Association of Colorado 0.00% No change 6,552 $91K
Virtus Advisers, LLC 0.03% Add +19.3% 5,148 $71K
Group One Trading LLC 0.00% Reduce -35.1% 4,824 $67K
Acadian Asset Management LLC 0.00% New 4,565 $63K
Ameritas Investment Partners, Inc. 0.00% No change 4,368 $60K
STRS Ohio 0.00% Reduce -67.9% 3,600 $50K
Amundi 0.00% Reduce -85.7% 1,954 $28K
Mirae Asset Global Investments Co., Ltd. 0.00% Reduce -7.8% 1,793 $27K
Amalgamated Bank 0.00% No change 1,440 $20K
Cwm, LLC 0.00% Add +118.2% 1,189 $16K
GF Fund Management Co. LTD. 0.00% — 1,130 $16K
Nisa Investment Advisors, LLC 0.00% Reduce -19.3% 980 $14K
SBI Securities Co., Ltd. 0.00% — 972 $13K
Russell Investments Group, Ltd. 0.00% Reduce -11.5% 881 $12K
US Bancorp \de 0.00% Add +7.8% 861 $12K
HM Payson & Co. 0.00% New 800 $11K
Blue Trust, Inc. 0.00% Add +1241.5% 711 $10K
Lindbrook Capital, LLC 0.00% Add +557.3% 677 $9K
Versant Capital Management, Inc 0.00% Add +93.5% 629 $9K
Sterling Capital Management LLC 0.00% Add +552.8% 594 $8K
PNC Financial Services Group, Inc. 0.00% Reduce -39.4% 416 $6K
Farther Finance Advisors, LLC 0.00% Reduce -5.9% 353 $5K
Signaturefd, LLC 0.00% Reduce -60.9% 352 $5K
Aster Capital Management (DIFC) Ltd 0.00% Reduce -18.9% 288 $4K
Osaic Holdings, Inc. 0.00% Reduce -69.4% 259 $4K
Manchester Capital Management LLC 0.00% No change 250 $3K
Daiwa Securities Group Inc. 0.00% No change 195 $3K
MeadowBrook Investment Advisors LLC 0.00% No change 200 $3K
Evelyn Partners Investment Management LLP 0.00% — 199 $3K
Asset Dedication, LLC 0.00% No change 184 $3K
Brooklyn Investment Group 0.00% New 161 $2K
Quadrant Capital Group LLC 0.00% Reduce -88.6% 158 $2K
Sittner & Nelson, LLC 0.00% No change 155 $2K
IFP Advisors, Inc 0.00% New 132 $2K
GAMMA Investing LLC 0.00% Add +89.5% 127 $2K
Albion Financial Group 0.00% No change 125 $2K
Caitong International Asset Management Co., Ltd 0.00% — 115 $2K
Private Wealth Management Group, LLC 0.00% Reduce -54.8% 104 $1K
EverSource Wealth Advisors, LLC 0.00% Add +9.5% 104 $1K
Gould Capital, LLC 0.00% No change 100 $1K
Harbor Investment Advisory, LLC 0.00% No change 100 $1K
CVA Family Office, LLC 0.00% Reduce -23.4% 72 $997
Parallel Advisors, LLC 0.00% Add +0.0% 70 $970
Truvestments Capital LLC 0.00% No change 68 $942
CIBC Private Wealth Group LLC 0.00% No change 49 $694
Rothschild Investment LLC 0.00% Reduce -12.5% 35 $485
Cassady Schiller Wealth Management, LLC 0.00% New 34 $471
Huntington National Bank 0.00% New 34 $471
Larson Financial Group LLC 0.00% New 31 $429
POM Investment Strategies, LLC 0.00% No change 24 $332
CoreCap Advisors, LLC 0.00% No change 23 $319
Allworth Financial LP 0.00% Reduce -52.3% 21 $304
MassMutual Private Wealth & Trust, FSB 0.00% Add +233.3% 20 $277
Key Financial Inc 0.00% No change 12 $166
Lowe Wealth Advisors, LLC 0.00% No change 10 $139
Colonial Trust Advisors 0.00% New 7 $97
Clearstead Advisors, LLC 0.00% No change 4 $56
Valley Wealth Managers, Inc. 0.00% No change 3 $42
Whittier Trust Co. of Nevada Inc. 0.00% No change 3 $41
CBIZ Investment Advisory Services, LLC 0.00% New 2 $28
Harbour Investments, Inc. 0.00% No change 1 $14
Covestor Ltd 0.00% No change 4 $0

"% of holder's portfolio" is PRTA's weight in each manager's 13F, not the share of Prothena Corp. PLC the manager owns.