PTC TherapeuticsPTCT
13F holders, Q4 2025 (December 31)353holders +59
82new positions
36sold out
9famous investors
$75.95avg. 13F price*
At the end of Q4 2025, 353 institutions reported holding PTC Therapeutics Inc. (PTCT) in their 13F filings, up 59 from Q3 2025. 82 opened new positions and 36 sold out. The largest holders were BlackRock, Inc. ($970.7M), Vanguard Group Inc. ($668.7M) and RTW Investments, LP ($588.4M). 9 famous investors held it, including Steve Cohen (0.1% of Point72 Asset Management's portfolio), David E. Shaw (0.1% of D. E. Shaw & Co.'s portfolio) and Jim Simons / Peter Brown (0.1% of Renaissance Technologies's portfolio).
- Company
- PTC Therapeutics Inc.
- CUSIP
- 69366J200
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 82 | $186.3M |
| Exits | 36 | $94.5M |
All 13F filers, Q3 2025 → Q4 2025: 18,509,836 shares bought and 8,508,254 shares sold, net +10,001,582 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 353 holders
| BlackRock, Inc. | 0.02% | Add +79.2% | 12,779,065 | $970.7M |
| Vanguard Group Inc. | 0.01% | Add +6.2% | 8,803,203 | $668.7M |
| RTW Investments, LP | 5.89% | No change | 7,746,415 | $588.4M |
| Janus Henderson Group PLC | 0.17% | Add +28.6% | 4,851,332 | $368.6M |
| State Street Corp. | 0.01% | Add +34.2% | 4,206,126 | $319.5M |
| Toronto Dominion Bank | 0.56% | Add +27.5% | 4,138,215 | $314.3M |
| Wellington Management Group LLP | 0.05% | Reduce -21.4% | 3,867,380 | $293.8M |
| Armistice Capital, LLC | 5.22% | Reduce -14.5% | 2,801,869 | $212.8M |
| Geode Capital Management, LLC | 0.01% | Add +3.3% | 2,016,062 | $153.2M |
| D. E. Shaw & Co. | 0.11% | Reduce -19.8% | 1,744,991 | $132.5M |
| FMR LLC | 0.01% | Add +4.3% | 1,681,216 | $127.7M |
| Jefferies Financial Group Inc. | 1.06% | Add +4.7% | 1,658,481 | $126.0M |
| Tang Capital Management LLC | 5.63% | No change | 1,500,000 | $113.9M |
| Bank of America Corp. | 0.01% | Reduce -5.6% | 1,431,557 | $108.7M |
| Franklin Resources Inc. | 0.02% | Add +11.2% | 1,286,685 | $97.7M |
| Citadel Advisors | 0.06% | Reduce -33.3% | 1,154,455 | $87.7M |
| Driehaus Capital Management LLC | 0.59% | Add +0.4% | 1,136,188 | $86.3M |
| Point72 Asset Management | 0.14% | Reduce -7.5% | 1,128,551 | $85.7M |
| Goldman Sachs Group Inc. | 0.01% | Add +16.7% | 1,023,091 | $77.7M |
| Hood River Capital Management LLC | 0.84% | Add +0.7% | 1,003,075 | $76.2M |
| Pictet Asset Management Holding SA | 0.07% | Reduce -30.5% | 978,957 | $74.8M |
| UBS Group AG | 0.01% | Add +113.3% | 964,658 | $73.3M |
| Morgan Stanley | 0.00% | Add +115.8% | 905,192 | $68.8M |
| Palo Alto Investors LP | 9.56% | Add +4.8% | 903,916 | $68.7M |
| SG Americas Securities, LLC | 0.09% | Add +587.5% | 894,461 | $67.9M |
| BNP Paribas Financial Markets | 0.04% | Add +4013.1% | 828,662 | $62.9M |
| Northern Trust Corp. | 0.01% | Add +4.3% | 769,420 | $58.4M |
| Charles Schwab Investment Management Inc. | 0.01% | Add +4.6% | 734,933 | $55.8M |
| Nuveen, LLC | 0.01% | Reduce -3.0% | 699,190 | $53.1M |
| Avoro Capital Advisors LLC | 0.51% | New | 685,000 | $52.0M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.06% | Reduce -19.1% | 647,585 | $49.2M |
| Lord, Abbett & Co. LLC | 0.15% | Add +65.9% | 627,106 | $47.6M |
| Dimensional Fund Advisors LP | 0.01% | Reduce -18.9% | 627,092 | $47.6M |
| Renaissance Technologies | 0.07% | Reduce -34.5% | 607,589 | $46.2M |
| Woodline Partners LP | 0.17% | Add +441.2% | 571,553 | $43.4M |
| Bank of New York Mellon Corp | 0.01% | Add +88.5% | 514,680 | $39.1M |
| Boston Partners | 0.04% | Add +34.9% | 487,977 | $37.1M |
| Principal Financial Group Inc. | 0.02% | Add +607.6% | 478,897 | $36.4M |
| T. Rowe Price Associates Inc. | 0.00% | Add +0.4% | 460,114 | $35.0M |
| Invesco Ltd. | 0.00% | Add +38.7% | 434,285 | $33.0M |
| MPM Bioimpact LLC | 3.74% | Reduce -1.9% | 430,013 | $32.7M |
| Manufacturers Life Insurance Company, The | 0.03% | Add +0.3% | 426,506 | $32.4M |
| Arrowstreet Capital, Limited Partnership | 0.02% | Add +25.6% | 406,410 | $30.9M |
| Rockefeller Capital Management L.P. | 0.06% | Reduce -14.4% | 405,536 | $30.8M |
| Legal & General Group Plc | 0.01% | Add +51.8% | 366,265 | $27.8M |
| Jupiter Asset Management Ltd. | 0.22% | New | 361,159 | $27.4M |
| Panagora Asset Management Inc. | 0.10% | Add +3.3% | 359,837 | $27.3M |
| JPMorgan Chase & Co. | 0.00% | Reduce -27.5% | 356,041 | $27.0M |
| AQR Capital Management | 0.01% | Add +3.2% | 341,927 | $26.0M |
| Voya Investment Management LLC | 0.03% | Add +19.0% | 339,146 | $25.8M |
| Public Sector Pension Investment Board | 0.08% | New | 324,636 | $24.7M |
| Ensign Peak Advisors, Inc | 0.04% | Reduce -2.8% | 280,572 | $21.3M |
| Russell Investments Group, Ltd. | 0.02% | Add +9.4% | 270,748 | $20.6M |
| Empowered Funds, LLC | 0.32% | Add +473.0% | 250,412 | $19.0M |
| Marshall Wace, LLP | 0.02% | Add +57.1% | 247,746 | $18.8M |
| Mackenzie Financial Corp. | 0.02% | Add +17.4% | 236,909 | $18.0M |
| Pacer Advisors, Inc. | 0.05% | Reduce -53.2% | 235,653 | $17.9M |
| Deutsche Bank AG | 0.01% | Add +189.5% | 231,268 | $17.6M |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 0.01% | Reduce -6.9% | 220,847 | $16.8M |
| Barclays PLC | 0.01% | Reduce -8.1% | 220,196 | $16.7M |
| Rhumbline Advisers | 0.01% | Add +82.6% | 207,950 | $15.8M |
| Boxer Capital Management, LLC | 3.33% | No change | 200,000 | $15.2M |
| Prudential Financial Inc. | 0.02% | Add +109.5% | 183,185 | $13.9M |
| Parkman Healthcare Partners LLC | 1.16% | Reduce -20.9% | 160,179 | $12.2M |
| BI Asset Management Fondsmaeglerselskab A/S | 0.11% | Add +67.9% | 159,477 | $12.1M |
| First Trust Advisors LP | 0.01% | Add +27.7% | 155,596 | $11.8M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.02% | Add +14.6% | 151,401 | $11.5M |
| Ameriprise Financial Inc. | 0.00% | Add +1288.4% | 147,584 | $11.2M |
| Swiss National Bank | 0.01% | Add +2.0% | 141,065 | $10.7M |
| Adage Capital Partners Gp, L.L.C. | 0.02% | Reduce -51.5% | 141,000 | $10.7M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +1.5% | 131,893 | $10.0M |
| Ikarian Capital, LLC | 1.17% | Reduce -57.7% | 118,657 | $9.0M |
| Federated Hermes, Inc. | 0.01% | Add +659.8% | 112,566 | $8.6M |
| Neuberger Berman Group LLC | 0.01% | Add +2993.7% | 111,590 | $8.5M |
| WCM Investment Management, LLC | 0.02% | Reduce -25.0% | 110,267 | $8.4M |
| Castleark Management LLC | 0.22% | New | 96,860 | $7.4M |
| Alliancebernstein L.P. | 0.00% | Add +2.5% | 94,308 | $7.2M |
| Sei Investments Co. | 0.01% | Add +57.9% | 92,089 | $7.0M |
| Wells Fargo & Company | 0.00% | Add +69.0% | 86,921 | $6.6M |
| Raymond James Financial Inc. | 0.00% | Add +3.5% | 85,998 | $6.5M |
| Pinnacle Associates Ltd. | 0.08% | Reduce -5.8% | 83,431 | $6.3M |
| Royce & Associates LP | 0.06% | Add +146.5% | 80,794 | $6.1M |
| Rafferty Asset Management, LLC | 0.02% | Reduce -22.3% | 78,507 | $6.0M |
| CANADA LIFE ASSURANCE Co | 0.01% | Add +130.0% | 78,150 | $5.9M |
| Abacus FCF Advisors LLC | 0.75% | New | 75,757 | $5.8M |
| Hillsdale Investment Management Inc. | 0.16% | Reduce -16.9% | 75,706 | $5.8M |
| Canada Pension Plan Investment Board | 0.00% | New | 75,400 | $5.7M |
| Schroder Investment Management Group | 0.00% | Add +112.8% | 72,597 | $5.5M |
| Alyeska Investment Group, L.P. | 0.02% | New | 72,307 | $5.5M |
| Informed Momentum Co LLC | 0.61% | New | 71,735 | $5.4M |
| Acadian Asset Management LLC | 0.01% | Add +187.8% | 69,504 | $5.3M |
| California State Teachers Retirement System | 0.01% | Add +5.8% | 68,293 | $5.2M |
| HRT Financial LP | 0.02% | Add +469.2% | 67,064 | $5.1M |
| Sector Gamma As | 1.07% | Reduce -47.6% | 61,923 | $4.7M |
| Rock Springs Capital Management LP | 0.24% | New | 61,879 | $4.7M |
| Victory Capital Management Inc. | 0.00% | Reduce -25.7% | 56,571 | $4.3M |
| Thrivent Financial for Lutherans | 0.01% | New | 55,169 | $4.2M |
| Assenagon Asset Management S.A. | 0.01% | Reduce -49.7% | 54,170 | $4.1M |
| Norges Bank | 0.00% | — | 53,807 | $4.1M |
| Segall Bryant & Hamill, LLC | 0.05% | Add +34.6% | 50,431 | $3.8M |
"% of holder's portfolio" is PTCT's weight in each manager's 13F, not the share of PTC Therapeutics Inc. the manager owns.