Uniqure NVQURE
13F holders, Q2 2025 (June 30)At the end of Q2 2025, 143 institutions reported holding Uniqure NV (QURE) in their 13F filings, up 2 from Q1 2025. 32 opened new positions and 30 sold out. The largest holders were RTW Investments, LP ($71.9M), EcoR1 Capital, LLC ($55.6M) and Vestal Point Capital, LP ($51.6M). 4 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio), Steve Cohen (0.0% of Point72 Asset Management's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Uniqure NV
- CUSIP
- N90064101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 32 | $50.5M |
| Exits | 30 | $31.3M |
All 13F filers, Q1 2025 → Q2 2025: 11,876,089 shares bought and 8,996,842 shares sold, net +2,879,247 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 143 holders
| RTW Investments, LP | 1.02% | Add +20.9% | 5,158,231 | $71.9M |
| EcoR1 Capital, LLC | 3.30% | No change | 3,988,971 | $55.6M |
| Vestal Point Capital, LP | 2.72% | Reduce -22.8% | 3,700,000 | $51.6M |
| Avoro Capital Advisors LLC | 0.88% | Add +66.7% | 3,625,000 | $50.5M |
| Aberdeen Group plc | 0.07% | Add +24.1% | 2,750,714 | $38.3M |
| Jefferies Financial Group Inc. | 0.50% | New | 2,095,931 | $29.2M |
| Nantahala Capital Management, LLC | 2.03% | Reduce -25.6% | 2,051,852 | $28.6M |
| JPMorgan Chase & Co. | 0.00% | Add +471.7% | 1,807,685 | $25.2M |
| Franklin Resources Inc. | 0.01% | Reduce -19.2% | 1,605,515 | $22.4M |
| Sofinnova Investments, Inc. | 1.48% | Add +185.5% | 1,558,356 | $21.7M |
| Integral Health Asset Management, LLC | 1.76% | Add +8.0% | 1,350,000 | $18.8M |
| BlackRock, Inc. | 0.00% | Reduce -7.2% | 1,333,663 | $18.6M |
| 683 Capital Management, LLC | 1.93% | Reduce -17.1% | 1,285,000 | $17.9M |
| FMR LLC | 0.00% | Reduce -1.4% | 1,184,362 | $16.5M |
| State Street Corp. | 0.00% | Reduce -7.1% | 1,142,810 | $15.9M |
| Vanguard Group Inc. | 0.00% | Add +2.9% | 972,691 | $13.6M |
| Two Sigma Investments, LP | 0.02% | Add +2.7% | 940,960 | $13.1M |
| Morgan Stanley | 0.00% | Add +50.5% | 908,283 | $12.7M |
| Boxer Capital Management, LLC | 6.31% | Add +19.9% | 899,500 | $12.5M |
| Ameriprise Financial Inc. | 0.00% | Add +38.6% | 761,948 | $10.6M |
| Macquarie Group Ltd. | 0.01% | No change | 706,166 | $9.8M |
| Schroder Investment Management Group | 0.01% | Reduce -41.8% | 693,283 | $9.7M |
| Two Sigma Advisers, LP | 0.02% | Reduce -1.3% | 659,700 | $9.2M |
| Geode Capital Management, LLC | 0.00% | Reduce -1.3% | 603,210 | $8.4M |
| Stempoint Capital LP | 2.57% | Reduce -21.7% | 572,615 | $8.0M |
| Citadel Advisors | 0.01% | Reduce -29.2% | 555,865 | $7.7M |
| Balyasny Asset Management L.P. | 0.02% | Add +2054.1% | 536,968 | $7.5M |
| Pale Fire Capital SE | 0.77% | Add +14.6% | 529,798 | $7.4M |
| BNP Paribas Financial Markets | 0.01% | Add +4.6% | 503,672 | $7.0M |
| Privium Fund Management B.V. | 1.35% | Reduce -22.7% | 447,486 | $6.3M |
| Parkman Healthcare Partners LLC | 0.72% | Add +117.5% | 443,422 | $6.2M |
| Catalio Capital Management, LP | 1.22% | Reduce -49.7% | 417,443 | $5.8M |
| Royal Bank of Canada | 0.00% | Add +693.9% | 391,614 | $5.5M |
| Goldman Sachs Group Inc. | 0.00% | Add +37.3% | 356,463 | $5.0M |
| Bank of New York Mellon Corp | 0.00% | New | 348,328 | $4.9M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +4.6% | 292,931 | $4.1M |
| UBS Group AG | 0.00% | Add +16.2% | 263,668 | $3.7M |
| Marshall Wace, LLP | 0.00% | Add +276.5% | 222,979 | $3.1M |
| Avidity Partners Management LP | 0.58% | Reduce -38.4% | 207,000 | $2.9M |
| Silverarc Capital Management, LLC | 0.58% | Reduce -0.4% | 202,565 | $2.8M |
| Caption Management, LLC | 0.23% | Add +769.0% | 176,911 | $2.5M |
| Squarepoint Ops LLC | 0.01% | Reduce -1.3% | 176,002 | $2.5M |
| Woodline Partners LP | 0.01% | No change | 175,806 | $2.5M |
| Moore Capital Management, LP | 0.05% | Add +16.7% | 175,000 | $2.4M |
| PFM Health Sciences, LP | 0.22% | Reduce -70.9% | 174,331 | $2.4M |
| Invesco Ltd. | 0.00% | Reduce -65.6% | 166,799 | $2.3M |
| Hudson Bay Capital Management LP | 0.02% | Reduce -2.3% | 148,182 | $2.1M |
| Bank of America Corp. | 0.00% | Reduce -62.8% | 141,810 | $2.0M |
| Jennison Associates LLC | 0.00% | New | 140,060 | $2.0M |
| Affinity Asset Advisors, LLC | 0.29% | Reduce -66.3% | 135,000 | $1.9M |
| Schonfeld Strategic Advisors LLC | 0.01% | Add +220.2% | 134,948 | $1.9M |
| Millennium Management | 0.00% | Reduce -50.1% | 132,664 | $1.8M |
| Northern Trust Corp. | 0.00% | Add +27.1% | 125,685 | $1.8M |
| Voss Capital, LP | 0.12% | New | 125,000 | $1.7M |
| Ikarian Capital, LLC | 0.55% | New | 119,986 | $1.7M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | New | 110,576 | $1.5M |
| Russell Investments Group, Ltd. | 0.00% | Reduce -64.9% | 106,490 | $1.5M |
| Point72 Asset Management | 0.00% | Reduce -18.6% | 105,939 | $1.5M |
| Shay Capital LLC | 0.32% | Add +21.4% | 99,383 | $1.4M |
| Birchview Capital, LP | 1.37% | Add +11.3% | 98,697 | $1.4M |
| SG Americas Securities, LLC | 0.01% | New | 94,759 | $1.3M |
| Verition Fund Management LLC | 0.01% | Reduce -4.1% | 92,591 | $1.3M |
| Barclays PLC | 0.00% | Add +31.4% | 89,014 | $1.2M |
| Diamond Hill Capital Management, LLC (Investment Advisor) | 0.01% | No change | 82,653 | $1.2M |
| Swiss National Bank | 0.00% | New | 77,500 | $1.1M |
| SummitTX Capital, L.P. | 0.05% | New | 77,495 | $1.1M |
| Monaco Asset Management SAM | 0.37% | Reduce -6.7% | 70,000 | $976K |
| Rafferty Asset Management, LLC | 0.00% | Reduce -16.7% | 68,807 | $959K |
| Voya Investment Management LLC | 0.00% | Add +37.1% | 67,260 | $938K |
| Stifel Financial Corp. | 0.00% | Add +20.1% | 66,981 | $934K |
| Simplex Trading, LLC | 0.02% | Add +35.2% | 64,259 | $895K |
| Group One Trading LLC | 0.03% | Add +1696.4% | 63,681 | $888K |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0.03% | Reduce -44.8% | 63,475 | $885K |
| Y-Intercept (Hong Kong) Ltd | 0.02% | New | 62,538 | $872K |
| Main Management ETF Advisors, LLC | 0.03% | Add +1.6% | 56,420 | $786K |
| Sectoral Asset Management Inc. | 0.51% | Reduce -3.6% | 55,450 | $773K |
| Jane Street Group, LLC | 0.00% | Add +34.9% | 50,430 | $703K |
| Centiva Capital, LP | 0.05% | New | 50,000 | $697K |
| Susquehanna International Group, LLP | 0.00% | Add +16.8% | 48,283 | $673K |
| Headlands Technologies LLC | 0.07% | Add +304.4% | 42,444 | $592K |
| Raymond James Financial Inc. | 0.00% | Reduce -4.5% | 40,289 | $562K |
| Massar Capital Management, LP | 0.42% | No change | 40,000 | $558K |
| California State Teachers Retirement System | 0.00% | New | 38,707 | $540K |
| Susquehanna Fundamental Investments, LLC | 0.01% | No change | 38,534 | $537K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -47.6% | 37,213 | $518K |
| Legal & General Group Plc | 0.00% | New | 35,621 | $497K |
| Aquatic Capital Management LLC | 0.01% | Add +233.0% | 35,262 | $492K |
| Boothbay Fund Management, LLC | 0.01% | Reduce -11.0% | 33,612 | $469K |
| Hennion & Walsh Asset Management, Inc. | 0.02% | New | 30,369 | $423K |
| HRT Financial LP | 0.00% | New | 28,420 | $396K |
| Engineers Gate Manager LP | 0.00% | New | 27,904 | $389K |
| D. E. Shaw & Co. | 0.00% | New | 27,531 | $384K |
| DNB Asset Management AS | 0.00% | Reduce -0.6% | 25,159 | $351K |
| Militia Capital Partners, LP | 0.15% | New | 22,200 | $309K |
| Citigroup Inc. | 0.00% | Reduce -78.3% | 20,482 | $286K |
| Virtu Financial LLC | 0.01% | New | 19,850 | $277K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +706.4% | 19,804 | $276K |
| Bellevue Group AG | 0.01% | Reduce -12.8% | 19,610 | $273K |
| Algert Global LLC | 0.01% | New | 19,340 | $270K |
| Janus Henderson Group PLC | 0.00% | New | 16,900 | $236K |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.00% | New | 15,420 | $215K |
| Farallon Capital Management, L.L.C. | 0.00% | No change | 14,000 | $195K |
| Profund Advisors LLC | 0.01% | Reduce -16.1% | 13,716 | $191K |
| Wolverine Trading, LLC | 0.00% | Add +27.3% | 13,791 | $191K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Reduce -6.6% | 12,751 | $178K |
| Total Clarity Wealth Management, Inc. | 0.05% | Reduce -18.9% | 12,450 | $174K |
| Clear Harbor Asset Management, LLC | 0.01% | Reduce -9.3% | 12,250 | $171K |
| Arizona State Retirement System | 0.00% | New | 11,824 | $165K |
| China Universal Asset Management Co., Ltd. | 0.01% | Reduce -5.0% | 10,996 | $153K |
| Wells Fargo & Company | 0.00% | Reduce -11.3% | 10,942 | $153K |
| Teacher Retirement System of Texas | 0.00% | New | 10,808 | $151K |
| Corient Private Wealth LP | 0.00% | No change | 10,630 | $148K |
| KLP Kapitalforvaltning As | 0.00% | New | 8,400 | $117K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +358.0% | 7,085 | $99K |
| Virtus Investment Advisers, LLC | 0.03% | Reduce -46.1% | 5,881 | $82K |
| Activest Wealth Management | 0.02% | No change | 5,000 | $70K |
| Future Financial Wealth Managment LLC | 0.04% | No change | 4,000 | $56K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +16.9% | 2,115 | $29K |
| SBI Securities Co., Ltd. | 0.00% | Add +138.0% | 1,730 | $24K |
| Point72 Hong Kong Ltd | 0.00% | New | 1,465 | $20K |
| GF Fund Management Co. LTD. | 0.00% | No change | 1,248 | $17K |
| Toronto Dominion Bank | 0.00% | New | 1,200 | $17K |
| Covestor Ltd | 0.01% | New | 1,183 | $16K |
| FNY Investment Advisers, LLC | 0.01% | New | 936 | $13K |
| National Bank of Canada | 0.00% | Reduce -19.4% | 779 | $11K |
| US Bancorp \de | 0.00% | Add +9.0% | 737 | $10K |
| Brooklyn Investment Group | 0.00% | New | 447 | $6K |
| Wilmington Savings Fund Society, FSB | 0.00% | No change | 352 | $5K |
| Salem Investment Counselors Inc. | 0.00% | No change | 300 | $4K |
| Versant Capital Management, Inc | 0.00% | Reduce -24.1% | 249 | $3K |
| Signaturefd, LLC | 0.00% | Reduce -52.5% | 249 | $3K |
| Comerica Bank | 0.00% | New | 244 | $3K |
| Caitong International Asset Management Co., Ltd | 0.00% | Add +140.6% | 231 | $3K |
| Cwm, LLC | 0.00% | No change | 234 | $3K |
| Toth Financial Advisory Corp. | 0.00% | No change | 165 | $2K |
| Allworth Financial LP | 0.00% | No change | 164 | $2K |
| Daiwa Securities Group Inc. | 0.00% | No change | 158 | $2K |
| Osaic Holdings, Inc. | 0.00% | Reduce -38.7% | 111 | $2K |
| EverSource Wealth Advisors, LLC | 0.00% | No change | 109 | $2K |
| Jones Financial Companies LLLP | 0.00% | No change | 100 | $1K |
| Lanark Financial, Inc. | 0.00% | New | 3 | $1K |
| First Horizon Advisors, Inc. | 0.00% | Reduce -72.7% | 3 | $42 |
| Huntington National Bank | 0.00% | No change | 2 | $28 |
"% of holder's portfolio" is QURE's weight in each manager's 13F, not the share of Uniqure NV the manager owns.