Rapport TherapeuticsRAPP

13F holders, Q4 2025 (December 31)
144holders +20
36new positions
20sold out
5famous investors
$30.34avg. 13F price*

At the end of Q4 2025, 144 institutions reported holding Rapport Therapeutics Inc. (RAPP) in their 13F filings, up 20 from Q3 2025. 36 opened new positions and 20 sold out. The largest holders were TRV GP V, LLC ($216.5M), FMR LLC ($215.8M) and ARCH Venture Management, LLC ($113.1M). 5 famous investors held it, including David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).

Company
Rapport Therapeutics Inc.
CUSIP
75383L102
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150200 Q2 2024: 35Q2 2024Q3 2024: 55Q3 2024Q4 2024: 70Q4 2024Q1 2025: 77Q1 2025Q2 2025: 82Q2 2025Q3 2025: 124Q3 2025Q4 2025: 144Q4 2025Q1 2026: 147Q1 2026Q2 2026: 160Q2 2026

Total Exit/New Position Q3 2025 → Q4 2025

InstitutionsTotal Value
New Positions36$32.7M
Exits20$28.2M

All 13F filers, Q3 2025 → Q4 2025: 4,949,169 shares bought and 3,165,561 shares sold, net +1,783,608 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 144 holders

TRV GP V, LLC 50.44% No change 7,135,233 $216.5M
FMR LLC 0.01% Add +2.8% 7,111,865 $215.8M
ARCH Venture Management, LLC 17.36% No change 3,728,738 $113.1M
Capital International Investors 0.02% No change 3,402,529 $103.2M
Cormorant Asset Management, LP 5.21% Reduce -5.2% 3,027,521 $91.9M
Goldman Sachs Group Inc. 0.01% Add +23.9% 3,001,879 $91.1M
BlackRock, Inc. 0.00% Add +55.1% 2,431,862 $73.8M
Sofinnova Investments, Inc. 2.49% Reduce -2.2% 1,904,408 $57.8M
Vanguard Group Inc. 0.00% Add +11.8% 1,817,757 $55.2M
Johnson & Johnson 9.75% No change 1,784,517 $54.1M
Baker Bros. Advisors LP 0.28% No change 1,547,090 $46.9M
Vestal Point Capital, LP 1.24% Add +16.8% 1,110,000 $33.7M
Polar Capital Holdings Plc 0.14% Add +7.0% 1,004,728 $30.5M
TRV GP Vi, LLC 19.80% No change 969,218 $29.4M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% Add +6.7% 952,371 $28.9M
T. Rowe Price Associates Inc. 0.00% Reduce -20.0% 881,609 $26.7M
Alliancebernstein L.P. 0.01% Reduce -7.9% 788,411 $23.9M
State Street Corp. 0.00% Add +92.3% 714,821 $21.7M
Siren, L.L.C. 0.64% Reduce -32.8% 708,469 $21.5M
Geode Capital Management, LLC 0.00% Add +30.3% 694,734 $21.1M
Perceptive Advisors LLC 0.38% Add +66.8% 673,923 $20.4M
T. Rowe Price Investment Management, Inc. 0.01% Reduce -12.5% 619,029 $18.8M
Invesco Ltd. 0.00% Add +69.1% 267,120 $8.1M
Prudential Financial Inc. 0.01% New 254,967 $7.7M
Burkehill Global Management, LP 0.52% No change 250,000 $7.6M
D. E. Shaw & Co. 0.01% New 247,315 $7.5M
Charles Schwab Investment Management Inc. 0.00% Add +20.7% 244,391 $7.4M
UBS Group AG 0.00% Reduce -59.4% 226,360 $6.9M
Northern Trust Corp. 0.00% Add +43.5% 220,815 $6.7M
Morgan Stanley 0.00% Reduce -23.4% 210,331 $6.4M
Millennium Management 0.00% Add +30.9% 201,825 $6.1M
Ensign Peak Advisors, Inc 0.01% No change 194,200 $5.9M
Sio Capital Management, LLC 0.93% No change 185,265 $5.6M
Kennedy Capital Management LLC 0.11% New 178,737 $5.4M
Adage Capital Partners Gp, L.L.C. 0.01% Reduce -66.7% 150,000 $4.6M
Artia Global Partners LP 0.68% Add +114.4% 138,508 $4.2M
Renaissance Technologies 0.01% Add +236.6% 118,814 $3.6M
TD Asset Management Inc 0.00% Reduce -15.9% 115,190 $3.5M
Swedbank AB 0.00% New 113,200 $3.4M
Informed Momentum Co LLC 0.29% Reduce -2.0% 85,555 $2.6M
Dimensional Fund Advisors LP 0.00% Add +636.9% 83,487 $2.5M
Manufacturers Life Insurance Company, The 0.00% Reduce -4.5% 78,659 $2.4M
DAFNA Capital Management LLC 0.54% No change 75,000 $2.3M
Bank of New York Mellon Corp 0.00% Add +56.2% 74,081 $2.2M
Nuveen, LLC 0.00% Add +224.3% 70,946 $2.2M
Voya Investment Management LLC 0.00% Add +395.8% 66,149 $2.0M
Trexquant Investment LP 0.02% Add +206.9% 62,979 $1.9M
Eversept Partners, LP 0.10% Reduce -58.7% 59,233 $1.8M
Citigroup Inc. 0.00% Add +3091.2% 56,484 $1.7M
Wellington Management Group LLP 0.00% Reduce -10.1% 56,457 $1.7M
Swiss National Bank 0.00% New 54,600 $1.7M
Barclays PLC 0.00% Add +96.5% 52,480 $1.6M
Two Sigma Investments, LP 0.00% Add +135.4% 50,619 $1.5M
American Century Companies Inc. 0.00% Add +156.7% 46,849 $1.4M
Acadian Asset Management LLC 0.00% Add +2896.7% 44,291 $1.3M
Alps Advisors Inc. 0.01% Add +128.9% 39,139 $1.2M
Sectoral Asset Management Inc. 0.95% Reduce -10.5% 38,925 $1.2M
ExodusPoint Capital Management, LP 0.01% New 34,651 $1.1M
Bank of America Corp. 0.00% Reduce -40.5% 34,553 $1.0M
Wells Fargo & Company 0.00% Add +138.5% 32,109 $974K
Rhumbline Advisers 0.00% Add +26.5% 30,726 $932K
California State Teachers Retirement System 0.00% Add +2335.2% 26,690 $810K
Legal & General Group Plc 0.00% Reduce -34.0% 22,384 $679K
Deutsche Bank AG 0.00% Add +244.6% 21,535 $653K
Dark Forest Capital Management LP 0.03% New 21,074 $639K
AQR Capital Management 0.00% Add +1.2% 20,878 $633K
Sei Investments Co. 0.00% Add +124.1% 18,268 $554K
PSP Research LLC 0.46% — 17,506 $531K
Brevan Howard Capital Management LP 0.01% New 16,783 $509K
MetLife Investment Management, LLC 0.00% Add +47.3% 15,996 $485K
JPMorgan Chase & Co. 0.00% Add +51.5% 15,129 $459K
Ameriprise Financial Inc. 0.00% Reduce -88.2% 14,794 $449K
Janus Henderson Group PLC 0.00% New 13,800 $419K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Add +64.5% 13,249 $402K
Allianz Asset Management GmbH 0.00% New 13,200 $400K
XTX Topco Ltd 0.01% New 13,062 $396K
Gsa Capital Partners LLP 0.03% New 12,733 $386K
BNP Paribas Financial Markets 0.00% Add +71.1% 12,353 $375K
Creative Planning 0.00% Add +2.1% 12,212 $371K
China Universal Asset Management Co., Ltd. 0.03% Add +45.5% 10,766 $327K
Susquehanna International Group, LLP 0.00% Reduce -51.7% 10,208 $310K
Catalyst Private Wealth, LLC 0.13% No change 10,000 $303K
Silverarc Capital Management, LLC 0.04% Reduce -95.3% 9,659 $293K
SG Americas Securities, LLC 0.00% Add +54.4% 9,673 $293K
Canada Pension Plan Investment Board 0.00% New 9,100 $276K
Profund Advisors LLC 0.01% New 8,880 $269K
Quadrature Capital Ltd 0.00% New 8,837 $268K
Virtus Investment Advisers, LLC 0.07% Reduce -13.9% 8,789 $267K
State of Wisconsin Investment Board 0.00% New 8,297 $252K
Citadel Advisors 0.00% Reduce -92.3% 8,099 $246K
Intech Investment Management LLC 0.00% New 8,026 $244K
Squarepoint Ops LLC 0.00% New 7,859 $238K
Rafferty Asset Management, LLC 0.00% New 7,801 $237K
Arizona State Retirement System 0.00% New 7,726 $234K
Police & Firemen's Retirement System of New Jersey 0.00% Add +42.3% 7,471 $227K
ProShare Advisors LLC 0.00% New 7,308 $222K
New York State Common Retirement Fund 0.00% No change 7,300 $221K
Susquehanna Portfolio Strategies, LLC 0.00% Reduce -6.6% 7,031 $213K
Stifel Financial Corp. 0.00% New 6,823 $207K
Landscape Capital Management, L.L.C. 0.01% New 6,594 $200K
AlphaCentric Advisors LLC 0.18% — 6,030 $183K
Sandia Investment Management LP 0.46% No change 6,000 $182K
Los Angeles Capital Management LLC 0.00% New 6,690 $180K
KLP Kapitalforvaltning As 0.00% New 5,900 $179K
AlphaQuest LLC 0.01% New 3,754 $114K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +64.1% 2,316 $70K
Ameritas Investment Partners, Inc. 0.00% Add +55.8% 2,310 $70K
Russell Investments Group, Ltd. 0.00% Add +57.0% 2,282 $69K
STRS Ohio 0.00% No change 2,100 $64K
Sterling Capital Management LLC 0.00% Add +35.4% 1,640 $50K
Cwm, LLC 0.00% Add +0.7% 1,468 $45K
Nisa Investment Advisors, LLC 0.00% No change 1,353 $41K
Meeder Asset Management Inc. 0.00% New 1,208 $37K
Tidemark, LLC 0.01% No change 1,088 $33K
Royal Bank of Canada 0.00% Add +0.7% 1,100 $33K
GF Fund Management Co. LTD. 0.00% Add +18.5% 935 $28K
Amalgamated Bank 0.00% Add +53.6% 894 $27K
Arax Advisory Partners 0.00% Reduce -11.3% 500 $15K
Tower Research Capital LLC (TRC) 0.00% Reduce -59.3% 430 $13K
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.00% New 420 $13K
GAMMA Investing LLC 0.00% Reduce -3.4% 342 $10K
Cygnus Capital Advisors, LLC 0.01% — 341 $10K
Aster Capital Management (DIFC) Ltd 0.00% New 300 $9K
Signaturefd, LLC 0.00% Add +9.8% 225 $7K
MassMutual Private Wealth & Trust, FSB 0.00% New 161 $5K
Daiwa Securities Group Inc. 0.00% No change 121 $4K
EverSource Wealth Advisors, LLC 0.00% No change 115 $3K
Larson Financial Group LLC 0.00% New 83 $3K
Optiver Holding B.V. 0.00% Reduce -32.1% 72 $2K
SBI Securities Co., Ltd. 0.00% Add +18.9% 63 $2K
Quadrant Capital Group LLC 0.00% No change 57 $2K
Federated Hermes, Inc. 0.00% New 55 $2K
Cornerstone Financial Management LLC 0.00% — 49 $1K
PNC Financial Services Group, Inc. 0.00% Reduce -9.6% 47 $1K
True Wealth Design, LLC 0.00% No change 44 $1K
Essential Partners LLC 0.00% No change 40 $1K
Global Retirement Partners, LLC 0.00% Reduce -11.1% 40 $1K
Simplex Trading, LLC 0.00% Reduce -99.8% 27 $819
SageView Advisory Group, LLC 0.00% New 16 $486
Bare Financial Services, Inc 0.00% New 16 $485
Sunbelt Securities, Inc. 0.00% No change 11 $334
Osaic Holdings, Inc. 0.00% New 9 $273
IFP Advisors, Inc 0.00% No change 3 $91
Farther Finance Advisors, LLC 0.00% New 1 $30

"% of holder's portfolio" is RAPP's weight in each manager's 13F, not the share of Rapport Therapeutics Inc. the manager owns.