Rapport TherapeuticsRAPP
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 144 institutions reported holding Rapport Therapeutics Inc. (RAPP) in their 13F filings, up 20 from Q3 2025. 36 opened new positions and 20 sold out. The largest holders were TRV GP V, LLC ($216.5M), FMR LLC ($215.8M) and ARCH Venture Management, LLC ($113.1M). 5 famous investors held it, including David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Rapport Therapeutics Inc.
- CUSIP
- 75383L102
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 36 | $32.7M |
| Exits | 20 | $28.2M |
All 13F filers, Q3 2025 → Q4 2025: 4,949,169 shares bought and 3,165,561 shares sold, net +1,783,608 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 144 holders
| TRV GP V, LLC | 50.44% | No change | 7,135,233 | $216.5M |
| FMR LLC | 0.01% | Add +2.8% | 7,111,865 | $215.8M |
| ARCH Venture Management, LLC | 17.36% | No change | 3,728,738 | $113.1M |
| Capital International Investors | 0.02% | No change | 3,402,529 | $103.2M |
| Cormorant Asset Management, LP | 5.21% | Reduce -5.2% | 3,027,521 | $91.9M |
| Goldman Sachs Group Inc. | 0.01% | Add +23.9% | 3,001,879 | $91.1M |
| BlackRock, Inc. | 0.00% | Add +55.1% | 2,431,862 | $73.8M |
| Sofinnova Investments, Inc. | 2.49% | Reduce -2.2% | 1,904,408 | $57.8M |
| Vanguard Group Inc. | 0.00% | Add +11.8% | 1,817,757 | $55.2M |
| Johnson & Johnson | 9.75% | No change | 1,784,517 | $54.1M |
| Baker Bros. Advisors LP | 0.28% | No change | 1,547,090 | $46.9M |
| Vestal Point Capital, LP | 1.24% | Add +16.8% | 1,110,000 | $33.7M |
| Polar Capital Holdings Plc | 0.14% | Add +7.0% | 1,004,728 | $30.5M |
| TRV GP Vi, LLC | 19.80% | No change | 969,218 | $29.4M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.01% | Add +6.7% | 952,371 | $28.9M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -20.0% | 881,609 | $26.7M |
| Alliancebernstein L.P. | 0.01% | Reduce -7.9% | 788,411 | $23.9M |
| State Street Corp. | 0.00% | Add +92.3% | 714,821 | $21.7M |
| Siren, L.L.C. | 0.64% | Reduce -32.8% | 708,469 | $21.5M |
| Geode Capital Management, LLC | 0.00% | Add +30.3% | 694,734 | $21.1M |
| Perceptive Advisors LLC | 0.38% | Add +66.8% | 673,923 | $20.4M |
| T. Rowe Price Investment Management, Inc. | 0.01% | Reduce -12.5% | 619,029 | $18.8M |
| Invesco Ltd. | 0.00% | Add +69.1% | 267,120 | $8.1M |
| Prudential Financial Inc. | 0.01% | New | 254,967 | $7.7M |
| Burkehill Global Management, LP | 0.52% | No change | 250,000 | $7.6M |
| D. E. Shaw & Co. | 0.01% | New | 247,315 | $7.5M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +20.7% | 244,391 | $7.4M |
| UBS Group AG | 0.00% | Reduce -59.4% | 226,360 | $6.9M |
| Northern Trust Corp. | 0.00% | Add +43.5% | 220,815 | $6.7M |
| Morgan Stanley | 0.00% | Reduce -23.4% | 210,331 | $6.4M |
| Millennium Management | 0.00% | Add +30.9% | 201,825 | $6.1M |
| Ensign Peak Advisors, Inc | 0.01% | No change | 194,200 | $5.9M |
| Sio Capital Management, LLC | 0.93% | No change | 185,265 | $5.6M |
| Kennedy Capital Management LLC | 0.11% | New | 178,737 | $5.4M |
| Adage Capital Partners Gp, L.L.C. | 0.01% | Reduce -66.7% | 150,000 | $4.6M |
| Artia Global Partners LP | 0.68% | Add +114.4% | 138,508 | $4.2M |
| Renaissance Technologies | 0.01% | Add +236.6% | 118,814 | $3.6M |
| TD Asset Management Inc | 0.00% | Reduce -15.9% | 115,190 | $3.5M |
| Swedbank AB | 0.00% | New | 113,200 | $3.4M |
| Informed Momentum Co LLC | 0.29% | Reduce -2.0% | 85,555 | $2.6M |
| Dimensional Fund Advisors LP | 0.00% | Add +636.9% | 83,487 | $2.5M |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -4.5% | 78,659 | $2.4M |
| DAFNA Capital Management LLC | 0.54% | No change | 75,000 | $2.3M |
| Bank of New York Mellon Corp | 0.00% | Add +56.2% | 74,081 | $2.2M |
| Nuveen, LLC | 0.00% | Add +224.3% | 70,946 | $2.2M |
| Voya Investment Management LLC | 0.00% | Add +395.8% | 66,149 | $2.0M |
| Trexquant Investment LP | 0.02% | Add +206.9% | 62,979 | $1.9M |
| Eversept Partners, LP | 0.10% | Reduce -58.7% | 59,233 | $1.8M |
| Citigroup Inc. | 0.00% | Add +3091.2% | 56,484 | $1.7M |
| Wellington Management Group LLP | 0.00% | Reduce -10.1% | 56,457 | $1.7M |
| Swiss National Bank | 0.00% | New | 54,600 | $1.7M |
| Barclays PLC | 0.00% | Add +96.5% | 52,480 | $1.6M |
| Two Sigma Investments, LP | 0.00% | Add +135.4% | 50,619 | $1.5M |
| American Century Companies Inc. | 0.00% | Add +156.7% | 46,849 | $1.4M |
| Acadian Asset Management LLC | 0.00% | Add +2896.7% | 44,291 | $1.3M |
| Alps Advisors Inc. | 0.01% | Add +128.9% | 39,139 | $1.2M |
| Sectoral Asset Management Inc. | 0.95% | Reduce -10.5% | 38,925 | $1.2M |
| ExodusPoint Capital Management, LP | 0.01% | New | 34,651 | $1.1M |
| Bank of America Corp. | 0.00% | Reduce -40.5% | 34,553 | $1.0M |
| Wells Fargo & Company | 0.00% | Add +138.5% | 32,109 | $974K |
| Rhumbline Advisers | 0.00% | Add +26.5% | 30,726 | $932K |
| California State Teachers Retirement System | 0.00% | Add +2335.2% | 26,690 | $810K |
| Legal & General Group Plc | 0.00% | Reduce -34.0% | 22,384 | $679K |
| Deutsche Bank AG | 0.00% | Add +244.6% | 21,535 | $653K |
| Dark Forest Capital Management LP | 0.03% | New | 21,074 | $639K |
| AQR Capital Management | 0.00% | Add +1.2% | 20,878 | $633K |
| Sei Investments Co. | 0.00% | Add +124.1% | 18,268 | $554K |
| PSP Research LLC | 0.46% | — | 17,506 | $531K |
| Brevan Howard Capital Management LP | 0.01% | New | 16,783 | $509K |
| MetLife Investment Management, LLC | 0.00% | Add +47.3% | 15,996 | $485K |
| JPMorgan Chase & Co. | 0.00% | Add +51.5% | 15,129 | $459K |
| Ameriprise Financial Inc. | 0.00% | Reduce -88.2% | 14,794 | $449K |
| Janus Henderson Group PLC | 0.00% | New | 13,800 | $419K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +64.5% | 13,249 | $402K |
| Allianz Asset Management GmbH | 0.00% | New | 13,200 | $400K |
| XTX Topco Ltd | 0.01% | New | 13,062 | $396K |
| Gsa Capital Partners LLP | 0.03% | New | 12,733 | $386K |
| BNP Paribas Financial Markets | 0.00% | Add +71.1% | 12,353 | $375K |
| Creative Planning | 0.00% | Add +2.1% | 12,212 | $371K |
| China Universal Asset Management Co., Ltd. | 0.03% | Add +45.5% | 10,766 | $327K |
| Susquehanna International Group, LLP | 0.00% | Reduce -51.7% | 10,208 | $310K |
| Catalyst Private Wealth, LLC | 0.13% | No change | 10,000 | $303K |
| Silverarc Capital Management, LLC | 0.04% | Reduce -95.3% | 9,659 | $293K |
| SG Americas Securities, LLC | 0.00% | Add +54.4% | 9,673 | $293K |
| Canada Pension Plan Investment Board | 0.00% | New | 9,100 | $276K |
| Profund Advisors LLC | 0.01% | New | 8,880 | $269K |
| Quadrature Capital Ltd | 0.00% | New | 8,837 | $268K |
| Virtus Investment Advisers, LLC | 0.07% | Reduce -13.9% | 8,789 | $267K |
| State of Wisconsin Investment Board | 0.00% | New | 8,297 | $252K |
| Citadel Advisors | 0.00% | Reduce -92.3% | 8,099 | $246K |
| Intech Investment Management LLC | 0.00% | New | 8,026 | $244K |
| Squarepoint Ops LLC | 0.00% | New | 7,859 | $238K |
| Rafferty Asset Management, LLC | 0.00% | New | 7,801 | $237K |
| Arizona State Retirement System | 0.00% | New | 7,726 | $234K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +42.3% | 7,471 | $227K |
| ProShare Advisors LLC | 0.00% | New | 7,308 | $222K |
| New York State Common Retirement Fund | 0.00% | No change | 7,300 | $221K |
| Susquehanna Portfolio Strategies, LLC | 0.00% | Reduce -6.6% | 7,031 | $213K |
| Stifel Financial Corp. | 0.00% | New | 6,823 | $207K |
| Landscape Capital Management, L.L.C. | 0.01% | New | 6,594 | $200K |
"% of holder's portfolio" is RAPP's weight in each manager's 13F, not the share of Rapport Therapeutics Inc. the manager owns.