Regulus TherapeuticsRGLS
13F holders, Q1 2025 (March 31)74holders +5
13new positions
8sold out
4famous investors
$1.96avg. 13F price*
At the end of Q1 2025, 74 institutions reported holding Regulus Therapeutics Inc. (RGLS) in their 13F filings, up 5 from Q4 2024. 13 opened new positions and 8 sold out. The largest holders were Federated Hermes, Inc. ($39.2M), NEA Management Company, LLC ($11.3M) and Octagon Capital Advisors LP ($8.1M). 4 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Regulus Therapeutics Inc.
- CUSIP
- 75915K309
- Latest filing quarter
- Q1 2025
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 13 | $5.8M |
| Exits | 8 | $7.3M |
All 13F filers, Q4 2024 → Q1 2025: 7,842,969 shares bought and 7,755,280 shares sold, net +87,689 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 74 holders
| Federated Hermes, Inc. | 0.08% | Add +23.1% | 15,819,863 | $39.2M |
| NEA Management Company, LLC | 0.87% | No change | 6,467,802 | $11.3M |
| Octagon Capital Advisors LP | 1.76% | Reduce -4.4% | 4,637,076 | $8.1M |
| BlackRock, Inc. | 0.00% | Reduce -1.6% | 4,170,515 | $7.3M |
| Vanguard Group Inc. | 0.00% | Reduce -0.4% | 3,952,120 | $6.9M |
| Deep Track Capital, LP | 0.18% | No change | 3,262,564 | $5.7M |
| Vivo Capital, LLC | 0.62% | Reduce -46.1% | 2,696,426 | $4.7M |
| Baker Bros. Advisors LP | 0.05% | New | 2,694,044 | $4.7M |
| Point72 Asset Management | 0.01% | Add +119.9% | 1,968,293 | $3.4M |
| Geode Capital Management, LLC | 0.00% | Add +1.7% | 1,300,818 | $2.3M |
| State Street Corp. | 0.00% | Reduce -1.9% | 1,036,643 | $1.8M |
| Alyeska Investment Group, L.P. | 0.01% | Reduce -9.6% | 937,500 | $1.6M |
| DAFNA Capital Management LLC | 0.43% | Reduce -3.2% | 847,176 | $1.5M |
| Sphera Funds Management LTD. | 0.20% | New | 452,845 | $792K |
| Northern Trust Corp. | 0.00% | Reduce -2.8% | 444,344 | $778K |
| Victory Capital Management Inc. | 0.00% | Reduce -0.8% | 386,666 | $677K |
| Wells Fargo & Company | 0.00% | Add +481.1% | 204,314 | $358K |
| UBS Group AG | 0.00% | Add +105.1% | 184,891 | $324K |
| Charles Schwab Investment Management Inc. | 0.00% | No change | 178,879 | $313K |
| Susquehanna International Group, LLP | 0.00% | Add +316.8% | 150,813 | $264K |
| Bank of New York Mellon Corp | 0.00% | No change | 149,355 | $261K |
| Citadel Advisors | 0.00% | Reduce -4.7% | 148,280 | $259K |
| Renaissance Technologies | 0.00% | Add +26.3% | 147,900 | $259K |
| Goldman Sachs Group Inc. | 0.00% | Reduce -38.6% | 130,339 | $228K |
| Tyche Wealth Partners LLC | 0.05% | Add +14.6% | 121,589 | $213K |
| Nuveen, LLC | 0.00% | — | 85,602 | $150K |
| Velan Capital Investment Management LP | 0.14% | Add +14.3% | 80,000 | $140K |
| Morgan Stanley | 0.00% | Reduce -44.5% | 77,621 | $136K |
| JPMorgan Chase & Co. | 0.00% | Reduce -60.9% | 74,517 | $130K |
| AQR Capital Management | 0.00% | New | 68,580 | $120K |
| Barclays PLC | 0.00% | Reduce -32.8% | 64,636 | $113K |
| Rhumbline Advisers | 0.00% | Reduce -3.0% | 57,744 | $101K |
| Oppenheimer & Co. Inc. | 0.00% | New | 55,000 | $96K |
| New York State Common Retirement Fund | 0.00% | No change | 49,400 | $86K |
| Citigroup Inc. | 0.00% | Reduce -12.0% | 44,135 | $77K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +4.5% | 38,345 | $67K |
| LPL Financial LLC | 0.00% | Reduce -24.0% | 37,980 | $66K |
| Intech Investment Management LLC | 0.00% | Add +13.8% | 32,410 | $57K |
| Corebridge Financial, Inc. | 0.00% | Reduce -1.5% | 30,938 | $54K |
| Bank of America Corp. | 0.00% | Reduce -44.4% | 29,937 | $52K |
| T. Rowe Price Associates Inc. | 0.00% | No change | 29,597 | $52K |
| Invesco Ltd. | 0.00% | Reduce -2.6% | 29,460 | $52K |
| Alliancebernstein L.P. | 0.00% | No change | 26,880 | $47K |
| Voya Investment Management LLC | 0.00% | Reduce -7.4% | 21,368 | $37K |
| SG Americas Securities, LLC | 0.00% | Reduce -29.3% | 18,696 | $33K |
| Creative Planning | 0.00% | Add +1.3% | 14,304 | $25K |
| Cibc World Markets Corp. | 0.00% | New | 14,013 | $25K |
| ProShare Advisors LLC | 0.00% | Reduce -23.1% | 13,671 | $24K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 12,696 | $22K |
| FMR LLC | 0.00% | Add +127.3% | 12,629 | $22K |
| XTX Topco Ltd | 0.00% | New | 11,418 | $20K |
| Prospera Financial Services Inc | 0.00% | New | 11,058 | $19K |
| HRT Financial LP | 0.00% | New | 10,952 | $19K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -42.9% | 6,384 | $11K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 6,187 | $11K |
| Legal & General Group Plc | 0.00% | No change | 5,956 | $10K |
| Cwm, LLC | 0.00% | Add +1065.5% | 5,781 | $10K |
| California State Teachers Retirement System | 0.00% | No change | 4,576 | $8K |
| Cubist Systematic Strategies, LLC | 0.00% | New | 4,088 | $7K |
| BNP Paribas Financial Markets | 0.00% | Reduce -43.2% | 4,060 | $7K |
| Amalgamated Bank | 0.00% | No change | 2,185 | $4K |
| Royal Bank of Canada | 0.00% | Reduce -69.5% | 2,366 | $4K |
| Deutsche Bank AG | 0.00% | New | 2,252 | $4K |
| Osaic Holdings, Inc. | 0.00% | Add +150.6% | 2,005 | $4K |
| Point72 (DIFC) Ltd | 0.00% | New | 1,608 | $3K |
| SBI Securities Co., Ltd. | 0.00% | Add +187.1% | 1,183 | $2K |
| Nisa Investment Advisors, LLC | 0.00% | Add +23.7% | 940 | $2K |
| Sterling Capital Management LLC | 0.00% | Reduce -48.7% | 830 | $1K |
| Community Bank, N.A. | 0.00% | No change | 690 | $1K |
| Russell Investments Group, Ltd. | 0.00% | No change | 458 | $802 |
| Legacy Wealth Managment, LLC | 0.00% | New | 90 | $158 |
| True Wealth Design, LLC | 0.00% | New | 60 | $105 |
| EverSource Wealth Advisors, LLC | 0.00% | Reduce -43.9% | 46 | $81 |
| Accredited Wealth Management, LLC | 0.00% | No change | 2 | $4 |
"% of holder's portfolio" is RGLS's weight in each manager's 13F, not the share of Regulus Therapeutics Inc. the manager owns.