Regulus TherapeuticsRGLS

13F holders, Q4 2024 (December 31)
69holders −1
7new positions
11sold out
4famous investors
$1.58avg. 13F price*

At the end of Q4 2024, 69 institutions reported holding Regulus Therapeutics Inc. (RGLS) in their 13F filings, down 1 from Q3 2024. 7 opened new positions and 11 sold out. The largest holders were Federated Hermes, Inc. ($20.3M), NEA Management Company, LLC ($10.2M) and Vivo Capital, LLC ($7.9M). 4 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).

Company
Regulus Therapeutics Inc.
CUSIP
75915K309
Latest filing quarter
Q1 2025

History

Number of 13F holders

020406080 Q1 2024: 44Q1 2024Q2 2024: 62Q2 2024Q3 2024: 70Q3 2024Q4 2024: 69Q4 2024Q1 2025: 74Q1 2025

Total Exit/New Position Q3 2024 → Q4 2024

InstitutionsTotal Value
New Positions7$226K
Exits11$3.7M

All 13F filers, Q3 2024 → Q4 2024: 2,267,874 shares bought and 5,502,470 shares sold, net −3,234,596 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 69 holders

Federated Hermes, Inc. 0.04% No change 12,852,654 $20.3M
NEA Management Company, LLC 0.58% No change 6,467,802 $10.2M
Vivo Capital, LLC 0.89% No change 5,000,000 $7.9M
Octagon Capital Advisors LP 1.30% Add +13.7% 4,848,802 $7.7M
BlackRock, Inc. 0.00% Add +3.8% 4,236,569 $6.7M
Vanguard Group Inc. 0.00% Reduce -3.0% 3,967,091 $6.3M
Deep Track Capital, LP 0.19% No change 3,262,564 $5.2M
Millennium Management 0.00% Add +69.8% 2,192,158 $3.5M
Adage Capital Partners Gp, L.L.C. 0.01% No change 2,000,000 $3.2M
Geode Capital Management, LLC 0.00% Reduce -0.1% 1,279,331 $2.0M
State Street Corp. 0.00% Add +5.5% 1,056,411 $1.7M
Alyeska Investment Group, L.P. 0.01% No change 1,037,500 $1.6M
Point72 Asset Management 0.00% Add +0.1% 895,128 $1.4M
DAFNA Capital Management LLC 0.36% Reduce -2.2% 875,200 $1.4M
Northern Trust Corp. 0.00% Reduce -8.1% 457,233 $722K
Victory Capital Management Inc. 0.00% Reduce -2.3% 389,886 $616K
Ra Capital Management, L.P. 0.01% Reduce -56.1% 336,843 $532K
Goldman Sachs Group Inc. 0.00% Add +18.6% 212,379 $336K
JPMorgan Chase & Co. 0.00% Add +141.2% 190,457 $301K
Charles Schwab Investment Management Inc. 0.00% No change 178,879 $283K
Citadel Advisors 0.00% Add +486018.8% 155,558 $246K
Bank of New York Mellon Corp 0.00% Reduce 0.0% 149,355 $236K
Morgan Stanley 0.00% Reduce -16.8% 139,791 $221K
Renaissance Technologies 0.00% Add +20.5% 117,100 $185K
Tyche Wealth Partners LLC 0.04% No change 106,089 $168K
Barclays PLC 0.00% Add +13.9% 96,247 $152K
UBS Group AG 0.00% Add +201.7% 90,147 $142K
Nuveen Asset Management, LLC 0.00% No change 85,602 $135K
Velan Capital Investment Management LP 0.10% New 70,000 $111K
PEAK6 LLC 0.00% — 60,000 $95K
Rhumbline Advisers 0.00% Reduce -20.1% 59,531 $94K
Bank of America Corp. 0.00% Reduce -1.1% 53,841 $85K
Citigroup Inc. 0.00% Reduce -6.7% 50,138 $79K
LPL Financial LLC 0.00% Reduce -13.8% 49,980 $79K
New York State Common Retirement Fund 0.00% No change 49,400 $78K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Add +4.4% 36,701 $58K
Susquehanna International Group, LLP 0.00% New 36,188 $57K
Wells Fargo & Company 0.00% Add +32.3% 35,159 $56K
Corebridge Financial, Inc. 0.00% Reduce -7.0% 31,397 $50K
Invesco Ltd. 0.00% Add +7.1% 30,248 $48K
T. Rowe Price Associates Inc. 0.00% Reduce -98.6% 29,597 $47K
Intech Investment Management LLC 0.00% New 28,480 $45K
Alliancebernstein L.P. 0.00% No change 26,880 $42K
SG Americas Securities, LLC 0.00% Add +27.2% 26,460 $42K
Voya Investment Management LLC 0.00% No change 23,074 $36K
Two Sigma Investments, LP 0.00% Add +16.1% 22,264 $35K
ProShare Advisors LLC 0.00% Add +49.0% 17,785 $28K
Creative Planning 0.00% Reduce -14.3% 14,116 $22K
Police & Firemen's Retirement System of New Jersey 0.00% — 12,696 $20K
Commonwealth Equity Services, LLC 0.00% Add +1.7% 11,700 $18K
Tower Research Capital LLC (TRC) 0.00% Add +61.8% 11,186 $18K
Royal Bank of Canada 0.00% Add +24.6% 7,752 $12K
BNP Paribas Financial Markets 0.00% New 7,151 $11K
Ameritas Investment Partners, Inc. 0.00% No change 6,187 $10K
Legal & General Group Plc 0.00% No change 5,956 $9K
FMR LLC 0.00% Reduce -98.3% 5,556 $9K
California State Teachers Retirement System 0.00% No change 4,576 $7K
Amalgamated Bank 0.00% No change 2,185 $3K
Sterling Capital Management LLC 0.00% Add +874.7% 1,618 $3K
Osaic Holdings, Inc. 0.00% No change 800 $1K
Nisa Investment Advisors, LLC 0.00% New 760 $1K
Community Bank, N.A. 0.00% No change 690 $1K
Cwm, LLC 0.00% Add +28.5% 496 $1K
Russell Investments Group, Ltd. 0.00% New 458 $724
SBI Securities Co., Ltd. 0.00% — 412 $651
Continuum Advisory, LLC 0.00% No change 300 $474
EverSource Wealth Advisors, LLC 0.00% New 82 $130
Accredited Wealth Management, LLC 0.00% — 2 $4
Lazard Asset Management LLC 0.00% No change 122 $0

"% of holder's portfolio" is RGLS's weight in each manager's 13F, not the share of Regulus Therapeutics Inc. the manager owns.