Sionna TherapeuticsSION

13F holders, Q2 2025 (June 30)
65holders +18
26new positions
8sold out
4famous investors
$17.35avg. 13F price*

At the end of Q2 2025, 65 institutions reported holding Sionna Therapeutics Inc. (SION) in their 13F filings, up 18 from Q1 2025. 26 opened new positions and 8 sold out. The largest holders were Ra Capital Management, L.P. ($181.2M), TPG GP A, LLC ($117.0M) and Orbimed Advisors LLC ($64.3M). 4 famous investors held it, including Andreas Halvorsen (0.2% of Viking Global Investors's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).

Company
Sionna Therapeutics Inc.
CUSIP
829401108
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150 Q1 2025: 47Q1 2025Q2 2025: 65Q2 2025Q3 2025: 78Q3 2025Q4 2025: 101Q4 2025Q1 2026: 122Q1 2026Q2 2026: 146Q2 2026

Total Exit/New Position Q1 2025 → Q2 2025

InstitutionsTotal Value
New Positions26$22.7M
Exits8$5.3M

All 13F filers, Q1 2025 → Q2 2025: 3,364,116 shares bought and 1,407,668 shares sold, net +1,956,448 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 65 holders

Ra Capital Management, L.P. 3.05% No change 10,445,322 $181.2M
TPG GP A, LLC 6.24% Add +0.9% 6,744,962 $117.0M
Orbimed Advisors LLC 1.62% No change 3,704,959 $64.3M
Atlas Venture Life Science Advisors, LLC 9.68% No change 3,694,020 $64.1M
Viking Global Investors 0.16% Add +8.2% 3,195,181 $55.4M
Enavate Sciences Gp, LLC 24.35% No change 2,478,030 $43.0M
JPMorgan Chase & Co. 0.00% Add +2.4% 2,221,188 $38.5M
Perceptive Advisors LLC 0.79% Reduce -2.8% 1,216,045 $21.1M
Braidwell LP 0.90% New 1,081,855 $18.8M
Deerfield Management Company, L.P. 0.34% Add +29.9% 970,590 $16.8M
Aberdeen Group plc 0.03% Add +27.4% 950,547 $16.5M
T. Rowe Price Associates Inc. 0.00% Reduce -13.6% 861,238 $14.9M
Jennison Associates LLC 0.01% Reduce -12.5% 752,800 $13.1M
BlackRock, Inc. 0.00% Add +221.1% 637,104 $11.1M
Vanguard Group Inc. 0.00% Add +15.4% 630,351 $10.9M
Franklin Resources Inc. 0.00% No change 500,023 $8.7M
Baker Bros. Advisors LP 0.07% No change 400,000 $6.9M
Soleus Capital Management, L.P. 0.45% Add +56.7% 376,000 $6.5M
Siren, L.L.C. 0.29% No change 325,000 $5.6M
Geode Capital Management, LLC 0.00% Add +113.4% 289,275 $5.0M
Ameriprise Financial Inc. 0.00% Add +13.2% 236,813 $4.1M
Alyeska Investment Group, L.P. 0.01% No change 186,222 $3.2M
Silverarc Capital Management, LLC 0.66% Add +63.0% 186,015 $3.2M
Prudential Financial Inc. 0.00% Add +114.6% 135,185 $2.3M
Citadel Advisors 0.00% Reduce -60.2% 129,912 $2.3M
State Street Corp. 0.00% Add +764.7% 124,518 $2.2M
Rock Springs Capital Management LP 0.11% No change 99,429 $1.7M
Charles Schwab Investment Management Inc. 0.00% Add +43.6% 92,832 $1.6M
Northern Trust Corp. 0.00% Add +242.6% 91,890 $1.6M
Driehaus Capital Management LLC 0.01% Reduce -74.5% 83,850 $1.5M
Woodline Partners LP 0.01% No change 80,000 $1.4M
UBS Group AG 0.00% Add +360.9% 51,367 $891K
Holocene Advisors, LP 0.00% No change 50,000 $868K
TD Asset Management Inc 0.00% Reduce -9.8% 49,966 $867K
Goldman Sachs Group Inc. 0.00% Reduce -27.8% 46,048 $799K
Morgan Stanley 0.00% Add +1017.5% 44,018 $764K
Manufacturers Life Insurance Company, The 0.00% Add +13.4% 38,038 $660K
Renaissance Technologies 0.00% New 26,000 $451K
Bank of New York Mellon Corp 0.00% New 24,131 $419K
Barclays PLC 0.00% New 23,022 $399K
Rhumbline Advisers 0.00% New 17,670 $307K
Bantamac Capital, LLC 0.11% New 16,975 $295K
Polen Capital Management LLC 0.00% New 16,975 $295K
Nuveen, LLC 0.00% New 16,040 $278K
Susquehanna International Group, LLP 0.00% New 14,834 $257K
Millennium Management 0.00% Reduce -92.2% 14,034 $243K
Commonwealth Equity Services, LLC 0.00% New 14,017 $243K
Deutsche Bank AG 0.00% New 9,596 $166K
MetLife Investment Management, LLC 0.00% New 8,033 $139K
New York State Common Retirement Fund 0.00% New 6,800 $118K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% New 6,747 $117K
Wells Fargo & Company 0.00% New 6,374 $111K
Bank of America Corp. 0.00% Reduce -31.2% 6,012 $104K
Virtus Investment Advisers, LLC 0.03% New 5,535 $96K
Citigroup Inc. 0.00% New 4,380 $76K
Police & Firemen's Retirement System of New Jersey 0.00% New 2,608 $45K
STRS Ohio 0.00% New 2,300 $40K
BNP Paribas Financial Markets 0.00% New 1,761 $31K
Legal & General Group Plc 0.00% New 1,374 $24K
Ameritas Investment Partners, Inc. 0.00% New 1,259 $22K
California State Teachers Retirement System 0.00% New 770 $13K
Amalgamated Bank 0.00% New 421 $7K
Royal Bank of Canada 0.00% Reduce -90.3% 60 $1K
Hughes Financial Services, LLC 0.00% New 44 $747
Sterling Capital Management LLC 0.00% New 30 $521

"% of holder's portfolio" is SION's weight in each manager's 13F, not the share of Sionna Therapeutics Inc. the manager owns.