Sionna TherapeuticsSION
13F holders, Q3 2025 (September 30)78holders +13
19new positions
6sold out
4famous investors
$29.41avg. 13F price*
At the end of Q3 2025, 78 institutions reported holding Sionna Therapeutics Inc. (SION) in their 13F filings, up 13 from Q2 2025. 19 opened new positions and 6 sold out. The largest holders were Ra Capital Management, L.P. ($307.2M), TPG GP A, LLC ($198.4M) and Orbimed Advisors LLC ($109.0M). 4 famous investors held it, including Andreas Halvorsen (0.2% of Viking Global Investors's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Sionna Therapeutics Inc.
- CUSIP
- 829401108
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 19 | $5.0M |
| Exits | 6 | $4.6M |
All 13F filers, Q2 2025 → Q3 2025: 1,606,760 shares bought and 2,214,590 shares sold, net −607,830 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 78 holders
| Ra Capital Management, L.P. | 3.79% | No change | 10,445,322 | $307.2M |
| TPG GP A, LLC | 10.80% | No change | 6,744,962 | $198.4M |
| Orbimed Advisors LLC | 2.61% | No change | 3,704,959 | $109.0M |
| Atlas Venture Life Science Advisors, LLC | 14.13% | Reduce -2.1% | 3,615,527 | $106.3M |
| Viking Global Investors | 0.24% | No change | 3,195,181 | $94.0M |
| Enavate Sciences Gp, LLC | 22.25% | No change | 2,478,030 | $72.9M |
| JPMorgan Chase & Co. | 0.00% | Reduce -10.9% | 1,978,626 | $58.2M |
| Perceptive Advisors LLC | 1.02% | Reduce -3.0% | 1,179,098 | $34.7M |
| Vanguard Group Inc. | 0.00% | Add +81.3% | 1,143,154 | $33.6M |
| Jennison Associates LLC | 0.02% | Add +32.5% | 997,375 | $29.3M |
| Deerfield Management Company, L.P. | 0.47% | No change | 970,590 | $28.5M |
| Aberdeen Group plc | 0.04% | No change | 950,547 | $28.0M |
| BlackRock, Inc. | 0.00% | Add +32.6% | 844,605 | $24.8M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -25.9% | 637,760 | $18.8M |
| Soleus Capital Management, L.P. | 0.65% | Add +10.0% | 413,500 | $12.2M |
| Baker Bros. Advisors LP | 0.09% | No change | 400,000 | $11.8M |
| Siren, L.L.C. | 0.37% | No change | 325,000 | $9.6M |
| Geode Capital Management, LLC | 0.00% | Add +9.4% | 316,564 | $9.3M |
| Braidwell LP | 0.37% | Reduce -71.0% | 314,013 | $9.2M |
| Franklin Resources Inc. | 0.00% | Reduce -51.6% | 242,147 | $7.1M |
| State Street Corp. | 0.00% | Add +92.9% | 240,199 | $7.1M |
| Millennium Management | 0.01% | Add +1425.5% | 214,085 | $6.3M |
| Alyeska Investment Group, L.P. | 0.02% | No change | 186,222 | $5.5M |
| Ameriprise Financial Inc. | 0.00% | Reduce -35.3% | 153,151 | $4.5M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +20.1% | 111,496 | $3.3M |
| Silverarc Capital Management, LLC | 0.46% | Reduce -41.5% | 108,801 | $3.2M |
| Rock Springs Capital Management LP | 0.17% | No change | 99,429 | $2.9M |
| Northern Trust Corp. | 0.00% | Add +6.3% | 97,711 | $2.9M |
| TD Asset Management Inc | 0.00% | Add +74.3% | 87,082 | $2.6M |
| Driehaus Capital Management LLC | 0.02% | No change | 83,850 | $2.5M |
| Longaeva Partners L.P. | 0.39% | New | 61,457 | $1.8M |
| Holocene Advisors, LP | 0.00% | No change | 50,000 | $1.5M |
| UBS Group AG | 0.00% | Reduce -9.2% | 46,666 | $1.4M |
| Wellington Management Group LLP | 0.00% | New | 42,234 | $1.2M |
| Citadel Advisors | 0.00% | Reduce -72.3% | 35,923 | $1.1M |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -15.7% | 32,080 | $943K |
| Polen Capital Management LLC | 0.00% | Add +84.1% | 31,258 | $919K |
| Marshall Wace, LLP | 0.00% | New | 30,103 | $885K |
| Bank of New York Mellon Corp | 0.00% | Add +13.8% | 27,463 | $808K |
| Morgan Stanley | 0.00% | Reduce -48.1% | 22,837 | $672K |
| Barclays PLC | 0.00% | Reduce -23.4% | 17,643 | $519K |
| Rhumbline Advisers | 0.00% | Reduce -2.4% | 17,240 | $507K |
| Nuveen, LLC | 0.00% | No change | 16,040 | $472K |
| Renaissance Technologies | 0.00% | Reduce -43.9% | 14,600 | $429K |
| Goldman Sachs Group Inc. | 0.00% | Reduce -73.5% | 12,178 | $358K |
| Squarepoint Ops LLC | 0.00% | New | 10,162 | $299K |
| Deutsche Bank AG | 0.00% | No change | 9,596 | $282K |
| Jain Global LLC | 0.00% | New | 8,513 | $250K |
| MetLife Investment Management, LLC | 0.00% | No change | 8,033 | $236K |
| Wells Fargo & Company | 0.00% | Add +18.9% | 7,576 | $223K |
| Intech Investment Management LLC | 0.00% | New | 7,486 | $220K |
| Legal & General Group Plc | 0.00% | Add +436.7% | 7,374 | $217K |
| Virtus Investment Advisers, LLC | 0.06% | Add +21.0% | 6,698 | $197K |
| Bank of America Corp. | 0.00% | Add +8.8% | 6,541 | $192K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -16.4% | 5,643 | $166K |
| New York State Common Retirement Fund | 0.00% | Reduce -22.1% | 5,300 | $156K |
| China Universal Asset Management Co., Ltd. | 0.01% | New | 5,000 | $147K |
| Tower Research Capital LLC (TRC) | 0.00% | New | 4,490 | $132K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +24.0% | 3,234 | $95K |
| BNP Paribas Financial Markets | 0.00% | Add +35.1% | 2,380 | $70K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 1,259 | $37K |
| Russell Investments Group, Ltd. | 0.00% | New | 1,022 | $30K |
| California State Teachers Retirement System | 0.00% | Add +0.1% | 771 | $23K |
| Citigroup Inc. | 0.00% | Reduce -84.3% | 687 | $20K |
| Aster Capital Management (DIFC) Ltd | 0.01% | New | 409 | $12K |
| Amalgamated Bank | 0.00% | No change | 421 | $12K |
| Royal Bank of Canada | 0.00% | Add +530.0% | 378 | $11K |
| FMR LLC | 0.00% | New | 234 | $7K |
| GAMMA Investing LLC | 0.00% | New | 153 | $5K |
| Federated Hermes, Inc. | 0.00% | New | 113 | $3K |
| US Bancorp \de | 0.00% | New | 111 | $3K |
| Arax Advisory Partners | 0.00% | New | 92 | $3K |
| Cwm, LLC | 0.00% | New | 60 | $2K |
| Hughes Financial Services, LLC | 0.00% | No change | 44 | $2K |
| Sterling Capital Management LLC | 0.00% | No change | 30 | $882 |
| Allworth Financial LP | 0.00% | New | 22 | $648 |
| EverSource Wealth Advisors, LLC | 0.00% | New | 20 | $588 |
| PNC Financial Services Group, Inc. | 0.00% | New | 5 | $147 |
"% of holder's portfolio" is SION's weight in each manager's 13F, not the share of Sionna Therapeutics Inc. the manager owns.