Sionna TherapeuticsSION
13F holders, Q4 2025 (December 31)101holders +23
27new positions
7sold out
4famous investors
$41.14avg. 13F price*
At the end of Q4 2025, 101 institutions reported holding Sionna Therapeutics Inc. (SION) in their 13F filings, up 23 from Q3 2025. 27 opened new positions and 7 sold out. The largest holders were Ra Capital Management, L.P. ($407.5M), TPG GP A, LLC ($277.5M) and Orbimed Advisors LLC ($146.5M). 4 famous investors held it, including Andreas Halvorsen (0.3% of Viking Global Investors's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Sionna Therapeutics Inc.
- CUSIP
- 829401108
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 27 | $54.8M |
| Exits | 7 | $12.3M |
All 13F filers, Q3 2025 → Q4 2025: 4,039,495 shares bought and 3,131,357 shares sold, net +908,138 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 101 holders
| Ra Capital Management, L.P. | 4.18% | Reduce -5.2% | 9,905,045 | $407.5M |
| TPG GP A, LLC | 10.33% | No change | 6,744,962 | $277.5M |
| Orbimed Advisors LLC | 3.00% | Reduce -3.9% | 3,561,655 | $146.5M |
| Viking Global Investors | 0.35% | No change | 3,195,181 | $131.4M |
| Atlas Venture Life Science Advisors, LLC | 14.24% | Reduce -17.1% | 2,995,602 | $123.2M |
| Enavate Sciences Gp, LLC | 20.12% | No change | 2,478,030 | $101.9M |
| BlackRock, Inc. | 0.00% | Add +52.9% | 1,291,599 | $53.1M |
| JPMorgan Chase & Co. | 0.00% | Reduce -37.7% | 1,231,819 | $50.7M |
| Vanguard Group Inc. | 0.00% | Add +3.7% | 1,184,951 | $48.7M |
| Perceptive Advisors LLC | 0.89% | No change | 1,179,098 | $48.5M |
| Jennison Associates LLC | 0.03% | Add +11.8% | 1,115,278 | $45.9M |
| Citadel Advisors | 0.03% | Add +2926.8% | 1,087,325 | $44.7M |
| Deerfield Management Company, L.P. | 0.58% | No change | 970,590 | $39.9M |
| Aberdeen Group plc | 0.05% | Reduce -11.6% | 839,960 | $34.6M |
| T. Rowe Price Associates Inc. | 0.00% | Add +30.4% | 831,373 | $34.2M |
| State Street Corp. | 0.00% | Add +188.7% | 693,395 | $28.5M |
| Eventide Asset Management, LLC | 0.41% | New | 639,045 | $26.3M |
| Baker Bros. Advisors LP | 0.10% | No change | 400,000 | $16.5M |
| Geode Capital Management, LLC | 0.00% | Add +20.1% | 380,042 | $15.6M |
| Siren, L.L.C. | 0.37% | Reduce -7.7% | 300,000 | $12.3M |
| Soleus Capital Management, L.P. | 0.47% | Reduce -35.1% | 268,500 | $11.0M |
| Kalehua Capital Management LLC | 8.02% | — | 197,072 | $8.1M |
| Superstring Capital Management LP | 3.98% | New | 180,593 | $7.4M |
| Franklin Resources Inc. | 0.00% | Reduce -27.5% | 175,483 | $7.2M |
| Alyeska Investment Group, L.P. | 0.02% | Reduce -26.9% | 136,222 | $5.6M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +10.9% | 123,686 | $5.1M |
| Artia Global Partners LP | 0.79% | New | 119,741 | $4.9M |
| TD Asset Management Inc | 0.00% | Add +30.2% | 113,352 | $4.7M |
| Northern Trust Corp. | 0.00% | Add +14.7% | 112,116 | $4.6M |
| Invesco Ltd. | 0.00% | New | 111,162 | $4.6M |
| Ameriprise Financial Inc. | 0.00% | Reduce -33.6% | 101,643 | $4.2M |
| Rock Springs Capital Management LP | 0.21% | No change | 99,429 | $4.1M |
| UBS Group AG | 0.00% | Add +91.1% | 89,177 | $3.7M |
| Driehaus Capital Management LLC | 0.02% | No change | 83,850 | $3.4M |
| Millennium Management | 0.00% | Reduce -62.4% | 80,546 | $3.3M |
| Ensign Peak Advisors, Inc | 0.01% | New | 79,862 | $3.3M |
| Longaeva Partners L.P. | 0.39% | Add +29.7% | 79,729 | $3.3M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +116.4% | 69,424 | $2.9M |
| Seven Grand Managers, LLC | 0.16% | New | 50,000 | $2.1M |
| Morgan Stanley | 0.00% | Add +118.4% | 49,876 | $2.1M |
| Barclays PLC | 0.00% | Add +173.0% | 48,172 | $2.0M |
| Bank of America Corp. | 0.00% | Add +566.1% | 43,567 | $1.8M |
| Silverarc Capital Management, LLC | 0.25% | Reduce -61.9% | 41,460 | $1.7M |
| Wellington Management Group LLP | 0.00% | Reduce -9.2% | 38,347 | $1.6M |
| Alps Advisors Inc. | 0.01% | New | 36,648 | $1.5M |
| Goldman Sachs Group Inc. | 0.00% | Add +197.8% | 36,269 | $1.5M |
| Bank of New York Mellon Corp | 0.00% | Add +27.9% | 35,134 | $1.4M |
| Polen Capital Management LLC | 0.01% | No change | 31,258 | $1.3M |
| Rafferty Asset Management, LLC | 0.00% | New | 24,690 | $1.0M |
| Nuveen, LLC | 0.00% | Add +48.0% | 23,734 | $976K |
| Russell Investments Group, Ltd. | 0.00% | Add +2046.9% | 21,941 | $903K |
| Rhumbline Advisers | 0.00% | Add +2.6% | 17,694 | $728K |
| Wells Fargo & Company | 0.00% | Add +131.7% | 17,551 | $722K |
| Squarepoint Ops LLC | 0.00% | Add +61.0% | 16,360 | $673K |
| Alliancebernstein L.P. | 0.00% | New | 15,620 | $643K |
| SG Americas Securities, LLC | 0.00% | New | 10,691 | $440K |
| China Universal Asset Management Co., Ltd. | 0.03% | Add +105.4% | 10,272 | $423K |
| Deutsche Bank AG | 0.00% | Add +4.5% | 10,029 | $413K |
| Profund Advisors LLC | 0.01% | New | 9,213 | $379K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +58.0% | 8,915 | $367K |
| MetLife Investment Management, LLC | 0.00% | Add +6.6% | 8,565 | $352K |
| Intech Investment Management LLC | 0.00% | Add +1.4% | 7,589 | $312K |
| Kennedy Capital Management LLC | 0.01% | New | 6,752 | $278K |
| Two Sigma Investments, LP | 0.00% | New | 6,400 | $263K |
| Virtus Investment Advisers, LLC | 0.07% | Reduce -7.1% | 6,220 | $256K |
| American Century Companies Inc. | 0.00% | New | 6,180 | $254K |
| Dark Forest Capital Management LP | 0.01% | New | 5,991 | $246K |
| D. E. Shaw & Co. | 0.00% | New | 5,742 | $236K |
| New York State Common Retirement Fund | 0.00% | No change | 5,300 | $218K |
| Citigroup Inc. | 0.00% | Add +654.7% | 5,185 | $213K |
| XTX Topco Ltd | 0.01% | New | 4,926 | $203K |
| ProShare Advisors LLC | 0.00% | New | 4,903 | $202K |
| Los Angeles Capital Management LLC | 0.00% | New | 5,189 | $197K |
| CIBC Private Wealth Group LLC | 0.00% | New | 4,500 | $185K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +30.9% | 4,232 | $174K |
| AlphaCentric Advisors LLC | 0.11% | — | 2,720 | $112K |
| Cygnus Capital Advisors, LLC | 0.08% | — | 2,400 | $99K |
| BNP Paribas Financial Markets | 0.00% | Reduce -4.9% | 2,264 | $93K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | New | 2,169 | $89K |
| Legal & General Group Plc | 0.00% | Reduce -77.2% | 1,682 | $69K |
| Balyasny Asset Management L.P. | 0.00% | New | 1,406 | $58K |
| Ameritas Investment Partners, Inc. | 0.00% | Add +3.4% | 1,302 | $54K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -74.9% | 1,129 | $46K |
| California State Teachers Retirement System | 0.00% | Add +28.1% | 988 | $41K |
| GF Fund Management Co. LTD. | 0.00% | New | 876 | $36K |
| Amalgamated Bank | 0.00% | Add +19.7% | 504 | $21K |
| Royal Bank of Canada | 0.00% | Add +29.4% | 489 | $21K |
| FMR LLC | 0.00% | Add +64.1% | 384 | $16K |
| Farther Finance Advisors, LLC | 0.00% | New | 190 | $8K |
| GAMMA Investing LLC | 0.00% | Add +15.7% | 177 | $7K |
| Daiwa Securities Group Inc. | 0.00% | New | 149 | $6K |
| Sterling Capital Management LLC | 0.00% | Add +250.0% | 105 | $4K |
| Cwm, LLC | 0.00% | Add +33.3% | 80 | $3K |
| US Bancorp \de | 0.00% | Reduce -41.4% | 65 | $3K |
| Rockefeller Capital Management L.P. | 0.00% | New | 48 | $2K |
| Aster Capital Management (DIFC) Ltd | 0.00% | Reduce -91.0% | 37 | $2K |
| Allworth Financial LP | 0.00% | Add +27.3% | 28 | $1K |
| Hughes Financial Services, LLC | 0.00% | Reduce -43.2% | 25 | $1K |
| EverSource Wealth Advisors, LLC | 0.00% | No change | 20 | $823 |
| PNC Financial Services Group, Inc. | 0.00% | No change | 5 | $206 |
"% of holder's portfolio" is SION's weight in each manager's 13F, not the share of Sionna Therapeutics Inc. the manager owns.