Skye BioscienceSKYE

13F holders, Q4 2025 (December 31)
50holders −8
14new positions
23sold out
1famous investor
$0.75avg. 13F price*

At the end of Q4 2025, 50 institutions reported holding Skye Bioscience Inc. (SKYE) in their 13F filings, down 8 from Q3 2025. 14 opened new positions and 23 sold out. The largest holders were 5AM Venture Management, LLC ($7.3M), Versant Venture Management, LLC ($1.5M) and Baker Bros. Advisors LP ($1.1M). One famous investor held it Israel Englander (0.0% of Millennium Management's portfolio).

Company
Skye Bioscience Inc.
CUSIP
83086J200
Latest filing quarter
Q2 2026

History

Number of 13F holders

020406080 Q1 2024: 3Q1 2024Q2 2024: 62Q2 2024Q3 2024: 74Q3 2024Q4 2024: 73Q4 2024Q1 2025: 75Q1 2025Q2 2025: 58Q2 2025Q3 2025: 58Q3 2025Q4 2025: 50Q4 2025Q1 2026: 39Q1 2026Q2 2026: 42Q2 2026

Total Exit/New Position Q3 2025 → Q4 2025

InstitutionsTotal Value
New Positions14$158K
Exits23$10.9M

All 13F filers, Q3 2025 → Q4 2025: 242,804 shares bought and 3,994,397 shares sold, net −3,751,593 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 50 holders

5AM Venture Management, LLC 2.28% No change 9,681,763 $7.3M
Versant Venture Management, LLC 1.00% No change 2,007,704 $1.5M
Baker Bros. Advisors LP 0.01% No change 1,450,638 $1.1M
Vanguard Group Inc. 0.00% No change 882,785 $662K
Sphera Funds Management LTD. 0.07% No change 478,928 $359K
Millennium Management 0.00% Reduce -5.4% 380,478 $285K
BlackRock, Inc. 0.00% Add +0.7% 281,841 $211K
Platinum Investment Management Ltd. 0.04% No change 233,095 $175K
Geode Capital Management, LLC 0.00% Add +0.7% 210,151 $158K
Schonfeld Strategic Advisors LLC 0.00% Reduce -92.1% 93,407 $70K
State Street Corp. 0.00% No change 75,326 $56K
XTX Topco Ltd 0.00% New 53,040 $40K
Two Sigma Investments, LP 0.00% Reduce -44.0% 51,706 $39K
Two Sigma Advisers, LP 0.00% New 40,982 $31K
HRT Financial LP 0.00% New 27,348 $20K
Jane Street Group, LLC 0.00% Add +93.3% 24,615 $18K
Engineers Gate Manager LP 0.00% New 23,138 $17K
Gsa Capital Partners LLP 0.00% New 22,877 $17K
Barclays PLC 0.00% New 21,251 $16K
Northern Trust Corp. 0.00% Reduce -30.6% 20,142 $15K
Group One Trading LLC 0.00% Add +634.3% 17,697 $13K
R Squared Ltd 0.01% New 14,782 $11K
UBS Group AG 0.00% Reduce -55.7% 13,286 $10K
Capital Advisors Inc. 0.00% No change 10,000 $7K
Simplex Trading, LLC 0.00% New 6,331 $5K
Morgan Stanley 0.00% Reduce -13.8% 4,269 $3K
Federated Hermes, Inc. 0.00% New 1,158 $868
FMR LLC 0.00% Reduce -93.7% 748 $561
Bank of America Corp. 0.00% Add +315.6% 586 $438
BNP Paribas Financial Markets 0.00% No change 510 $382
National Bank of Canada 0.00% New 400 $295
Fortitude Family Office, LLC 0.00% Add +237.7% 385 $289
JPMorgan Chase & Co. 0.00% New 66 $49
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% Reduce -99.8% 52 $39
Federation des caisses Desjardins du Quebec 0.00% No change 51 $38
Rockefeller Capital Management L.P. 0.00% No change 39 $29
TD Waterhouse Canada Inc. 0.00% No change 25 $18
Optiver Holding B.V. 0.00% No change 20 $15
NFSG Corp 0.00% No change 18 $13
Dynamic Wealth Strategies, LLC 0.00% New 8 $6
CoreCap Advisors, LLC 0.00% New 8 $6
Plante Moran Financial Advisors, LLC 0.00% No change 3 $2
McGuire Capital Advisors Inc. 0.00% — 2 $2
Wells Fargo & Company 0.00% No change 1 $1
Harbour Investments, Inc. 0.00% No change 1 $1
IFP Advisors, Inc 0.00% No change 1 $1
Osaic Holdings, Inc. 0.00% Reduce -88.9% 2 $1
Tucker Asset Management LLC 0.00% New 1 $1
PFS Partners, LLC 0.00% No change 1 $1
Royal Bank of Canada 0.00% Reduce -69.1% 124 $0

"% of holder's portfolio" is SKYE's weight in each manager's 13F, not the share of Skye Bioscience Inc. the manager owns.