Soleno TherapeuticsSLNO
13F holders, Q4 2025 (December 31)248holders +8
55new positions
48sold out
5famous investors
$46.31avg. 13F price*
At the end of Q4 2025, 248 institutions reported holding Soleno Therapeutics Inc. (SLNO) in their 13F filings, up 8 from Q3 2025. 55 opened new positions and 48 sold out. The largest holders were FMR LLC ($374.1M), Janus Henderson Group PLC ($332.3M) and BlackRock, Inc. ($179.3M). 5 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Joel Greenblatt (0.0% of Gotham Asset Management's portfolio).
- Company
- Soleno Therapeutics Inc.
- CUSIP
- 834203309
- Latest filing quarter
- Q1 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 55 | $186.3M |
| Exits | 48 | $485.9M |
All 13F filers, Q3 2025 → Q4 2025: 13,631,913 shares bought and 14,313,405 shares sold, net −681,492 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 248 holders
| FMR LLC | 0.02% | Add +1.0% | 8,079,304 | $374.1M |
| Janus Henderson Group PLC | 0.15% | Add +18.5% | 7,178,354 | $332.3M |
| BlackRock, Inc. | 0.00% | Add +10.9% | 3,871,639 | $179.3M |
| Wellington Management Group LLP | 0.03% | Add +43.7% | 3,322,799 | $153.8M |
| T. Rowe Price Associates Inc. | 0.02% | Reduce -15.0% | 3,318,698 | $153.7M |
| Vanguard Group Inc. | 0.00% | Add +9.0% | 3,060,361 | $141.7M |
| Avoro Capital Advisors LLC | 1.32% | Add +12.5% | 2,900,000 | $134.3M |
| State Street Corp. | 0.00% | Add +21.9% | 2,649,626 | $122.7M |
| Nantahala Capital Management, LLC | 3.64% | Add +52.1% | 1,314,002 | $60.8M |
| Millennium Management | 0.04% | Add +26.2% | 1,236,321 | $57.2M |
| Commodore Capital LP | 3.70% | Reduce -11.1% | 1,200,000 | $55.6M |
| Braidwell LP | 2.11% | Reduce -7.3% | 1,187,859 | $55.0M |
| Geode Capital Management, LLC | 0.00% | Add +7.2% | 1,163,338 | $53.9M |
| Polar Capital Holdings Plc | 0.24% | Reduce -4.5% | 1,136,929 | $52.6M |
| Woodline Partners LP | 0.20% | Add +310.5% | 1,111,778 | $51.5M |
| Deep Track Capital, LP | 1.06% | New | 1,000,000 | $46.3M |
| Goldman Sachs Group Inc. | 0.01% | Add +64.4% | 913,050 | $42.3M |
| Vivo Capital, LLC | 2.68% | Reduce -60.7% | 894,909 | $41.4M |
| Invesco Ltd. | 0.00% | Reduce -41.7% | 875,019 | $40.5M |
| Readystate Asset Management LP | 3.11% | Add +324.9% | 874,447 | $40.5M |
| Franklin Resources Inc. | 0.01% | Reduce -1.4% | 823,958 | $38.1M |
| Pictet Asset Management Holding SA | 0.03% | Add +13.3% | 624,128 | $28.9M |
| Bank of New York Mellon Corp | 0.01% | Reduce -0.9% | 621,811 | $28.8M |
| Hood River Capital Management LLC | 0.31% | Add +0.8% | 618,005 | $28.6M |
| Artia Global Partners LP | 3.97% | Reduce -20.6% | 533,698 | $24.7M |
| Squarepoint Ops LLC | 0.04% | Add +579.7% | 468,654 | $21.7M |
| Schroder Investment Management Group | 0.02% | Add +60.5% | 449,848 | $20.8M |
| Emerald Advisers, LLC | 0.59% | Reduce -34.3% | 412,651 | $19.1M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +3.0% | 401,186 | $18.6M |
| Great Point Partners LLC | 6.00% | Add +77.8% | 400,000 | $18.5M |
| Kingdon Capital Management, L.L.C. | 2.83% | Add +32.9% | 399,900 | $18.5M |
| Assenagon Asset Management S.A. | 0.03% | New | 384,166 | $17.8M |
| Northern Trust Corp. | 0.00% | Add +3.2% | 365,418 | $16.9M |
| Catalio Capital Management, LP | 2.95% | Reduce -13.8% | 360,340 | $16.7M |
| Integral Health Asset Management, LLC | 0.76% | New | 325,000 | $15.0M |
| Citadel Advisors | 0.01% | Reduce -31.4% | 308,830 | $14.3M |
| Logos Global Management LP | 0.93% | New | 300,000 | $13.9M |
| Morgan Stanley | 0.00% | Add +73.4% | 287,639 | $13.3M |
| Aberdeen Group plc | 0.02% | New | 287,456 | $13.3M |
| Qube Research & Technologies Ltd | 0.02% | Add +336.8% | 287,293 | $13.3M |
| Penn Capital Management Company, LLC | 1.02% | New | 275,782 | $12.8M |
| PFM Health Sciences, LP | 1.18% | Add +1.9% | 247,893 | $11.5M |
| Rock Springs Capital Management LP | 0.59% | Add +59.9% | 247,053 | $11.4M |
| Susquehanna International Group, LLP | 0.02% | Add +1425.5% | 244,358 | $11.3M |
| Emerald Mutual Fund Advisers Trust | 0.52% | Reduce -38.8% | 232,485 | $10.8M |
| Balyasny Asset Management L.P. | 0.02% | Reduce -65.5% | 227,751 | $10.5M |
| Alyeska Investment Group, L.P. | 0.03% | Add +13.0% | 217,500 | $10.1M |
| BNP Paribas Financial Markets | 0.01% | Add +2524.8% | 212,818 | $9.9M |
| SummitTX Capital, L.P. | 0.30% | Add +59.4% | 211,727 | $9.8M |
| Bank of America Corp. | 0.00% | Add +28.7% | 208,595 | $9.7M |
| Skandinaviska Enskilda Banken AB (publ) | 0.03% | Add +52.7% | 187,475 | $8.7M |
| New York State Common Retirement Fund | 0.01% | Add +1087.9% | 185,317 | $8.6M |
| Clark Capital Management Group, Inc. | 0.05% | New | 180,250 | $8.3M |
| UBS Group AG | 0.00% | Add +7.1% | 169,506 | $7.8M |
| Ally Bridge Group (NY) LLC | 12.35% | Reduce -44.5% | 168,029 | $7.8M |
| Engineers Gate Manager LP | 0.09% | New | 168,005 | $7.8M |
| Barclays PLC | 0.00% | Reduce -7.8% | 157,685 | $7.3M |
| Buckley Capital Advisors, LLC | 6.01% | — | 149,150 | $6.9M |
| Brevan Howard Capital Management LP | 0.14% | Add +936.5% | 147,800 | $6.8M |
| Capital World Investors | 0.00% | Reduce -82.3% | 145,522 | $6.7M |
| Deutsche Bank AG | 0.00% | Add +3.8% | 141,982 | $6.6M |
| Jane Street Group, LLC | 0.01% | New | 141,740 | $6.6M |
| Granahan Investment Management, LLC | 0.27% | Add +25.9% | 137,592 | $6.4M |
| Sphera Funds Management LTD. | 1.32% | Add +227.6% | 136,314 | $6.3M |
| Eagle Health Investments LP | 1.37% | New | 135,100 | $6.3M |
| HighVista Strategies LLC | 1.61% | Add +622.3% | 135,069 | $6.3M |
| Trexquant Investment LP | 0.05% | Add +1185.9% | 132,912 | $6.2M |
| Seven Fleet Capital Management LP | 4.08% | — | 130,079 | $6.0M |
| Royce & Associates LP | 0.06% | Add +316.4% | 129,043 | $6.0M |
| Nan Fung Trinity (hk) Ltd. | 0.45% | No change | 123,850 | $5.7M |
| Frontier Capital Management Co. LLC | 0.06% | Add +1.1% | 119,695 | $5.5M |
| Peregrine Capital Management LLC | 0.17% | Add +28.6% | 119,564 | $5.5M |
| Centiva Capital, LP | 0.33% | New | 118,804 | $5.5M |
| Silverarc Capital Management, LLC | 0.79% | New | 117,485 | $5.4M |
| JPMorgan Chase & Co. | 0.00% | Reduce -71.7% | 115,517 | $5.3M |
| Nuveen, LLC | 0.00% | Add +6.3% | 100,622 | $4.7M |
| Rafferty Asset Management, LLC | 0.02% | Add +3.4% | 95,597 | $4.4M |
| Swiss National Bank | 0.00% | Add +16.2% | 89,100 | $4.1M |
| Mutual of America Capital Management LLC | 0.04% | Add +5.5% | 83,166 | $3.9M |
| State of Wisconsin Investment Board | 0.01% | Add +80.3% | 72,482 | $3.4M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +23.9% | 72,360 | $3.4M |
| National Philanthropic Trust | 0.03% | New | 69,545 | $3.2M |
| Ikarian Capital, LLC | 0.41% | Add +23.0% | 68,823 | $3.2M |
| Sei Investments Co. | 0.00% | Reduce -40.9% | 67,330 | $3.1M |
| Atle Fund Management AB | 0.93% | Add +4.3% | 62,735 | $2.9M |
| KVP Capital Advisors, LP | 2.85% | — | 59,700 | $2.8M |
| AQR Capital Management | 0.00% | Add +58.4% | 58,752 | $2.7M |
| Rhumbline Advisers | 0.00% | Reduce -8.0% | 55,068 | $2.5M |
| Jump Financial, LLC | 0.03% | New | 54,487 | $2.5M |
| DV Trading LLC | 0.22% | — | 54,000 | $2.5M |
| Wells Fargo & Company | 0.00% | Add +72.7% | 52,643 | $2.4M |
| Simplex Trading, LLC | 0.06% | Add +95.6% | 49,108 | $2.3M |
| Lazard Asset Management LLC | 0.00% | Reduce -14.2% | 48,445 | $2.2M |
| Russell Investments Group, Ltd. | 0.00% | Reduce -50.5% | 46,678 | $2.2M |
| Moody Aldrich Partners LLC | 0.40% | Reduce -9.7% | 46,306 | $2.1M |
| WINTON GROUP Ltd | 0.07% | New | 44,200 | $2.0M |
| Boothbay Fund Management, LLC | 0.05% | Add +28.1% | 43,862 | $2.0M |
| Banque Pictet & Cie SA | 0.02% | New | 43,796 | $2.0M |
| Alliancebernstein L.P. | 0.00% | No change | 42,290 | $2.0M |
| Caption Management, LLC | 0.09% | Reduce -88.6% | 42,100 | $1.9M |
"% of holder's portfolio" is SLNO's weight in each manager's 13F, not the share of Soleno Therapeutics Inc. the manager owns.