Soleno TherapeuticsSLNO
13F holders, Q4 2025 (December 31)248holders +8
55new positions
48sold out
5famous investors
$46.31avg. 13F price*
At the end of Q4 2025, 248 institutions reported holding Soleno Therapeutics Inc. (SLNO) in their 13F filings, up 8 from Q3 2025. 55 opened new positions and 48 sold out. The largest holders were FMR LLC ($374.1M), Janus Henderson Group PLC ($332.3M) and BlackRock, Inc. ($179.3M). 5 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Joel Greenblatt (0.0% of Gotham Asset Management's portfolio).
- Company
- Soleno Therapeutics Inc.
- CUSIP
- 834203309
- Latest filing quarter
- Q1 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 55 | $186.3M |
| Exits | 48 | $485.9M |
All 13F filers, Q3 2025 → Q4 2025: 13,631,913 shares bought and 14,313,405 shares sold, net −681,492 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 248 holders
| FMR LLC | 0.02% | Add +1.0% | 8,079,304 | $374.1M |
| Janus Henderson Group PLC | 0.15% | Add +18.5% | 7,178,354 | $332.3M |
| BlackRock, Inc. | 0.00% | Add +10.9% | 3,871,639 | $179.3M |
| Wellington Management Group LLP | 0.03% | Add +43.7% | 3,322,799 | $153.8M |
| T. Rowe Price Associates Inc. | 0.02% | Reduce -15.0% | 3,318,698 | $153.7M |
| Vanguard Group Inc. | 0.00% | Add +9.0% | 3,060,361 | $141.7M |
| Avoro Capital Advisors LLC | 1.32% | Add +12.5% | 2,900,000 | $134.3M |
| State Street Corp. | 0.00% | Add +21.9% | 2,649,626 | $122.7M |
| Nantahala Capital Management, LLC | 3.64% | Add +52.1% | 1,314,002 | $60.8M |
| Millennium Management | 0.04% | Add +26.2% | 1,236,321 | $57.2M |
| Commodore Capital LP | 3.70% | Reduce -11.1% | 1,200,000 | $55.6M |
| Braidwell LP | 2.11% | Reduce -7.3% | 1,187,859 | $55.0M |
| Geode Capital Management, LLC | 0.00% | Add +7.2% | 1,163,338 | $53.9M |
| Polar Capital Holdings Plc | 0.24% | Reduce -4.5% | 1,136,929 | $52.6M |
| Woodline Partners LP | 0.20% | Add +310.5% | 1,111,778 | $51.5M |
| Deep Track Capital, LP | 1.06% | New | 1,000,000 | $46.3M |
| Goldman Sachs Group Inc. | 0.01% | Add +64.4% | 913,050 | $42.3M |
| Vivo Capital, LLC | 2.68% | Reduce -60.7% | 894,909 | $41.4M |
| Invesco Ltd. | 0.00% | Reduce -41.7% | 875,019 | $40.5M |
| Readystate Asset Management LP | 3.11% | Add +324.9% | 874,447 | $40.5M |
| Franklin Resources Inc. | 0.01% | Reduce -1.4% | 823,958 | $38.1M |
| Pictet Asset Management Holding SA | 0.03% | Add +13.3% | 624,128 | $28.9M |
| Bank of New York Mellon Corp | 0.01% | Reduce -0.9% | 621,811 | $28.8M |
| Hood River Capital Management LLC | 0.31% | Add +0.8% | 618,005 | $28.6M |
| Artia Global Partners LP | 3.97% | Reduce -20.6% | 533,698 | $24.7M |
| Squarepoint Ops LLC | 0.04% | Add +579.7% | 468,654 | $21.7M |
| Schroder Investment Management Group | 0.02% | Add +60.5% | 449,848 | $20.8M |
| Emerald Advisers, LLC | 0.59% | Reduce -34.3% | 412,651 | $19.1M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +3.0% | 401,186 | $18.6M |
| Great Point Partners LLC | 6.00% | Add +77.8% | 400,000 | $18.5M |
| Kingdon Capital Management, L.L.C. | 2.83% | Add +32.9% | 399,900 | $18.5M |
| Assenagon Asset Management S.A. | 0.03% | New | 384,166 | $17.8M |
| Northern Trust Corp. | 0.00% | Add +3.2% | 365,418 | $16.9M |
| Catalio Capital Management, LP | 2.95% | Reduce -13.8% | 360,340 | $16.7M |
| Integral Health Asset Management, LLC | 0.76% | New | 325,000 | $15.0M |
| Citadel Advisors | 0.01% | Reduce -31.4% | 308,830 | $14.3M |
| Logos Global Management LP | 0.93% | New | 300,000 | $13.9M |
| Morgan Stanley | 0.00% | Add +73.4% | 287,639 | $13.3M |
| Aberdeen Group plc | 0.02% | New | 287,456 | $13.3M |
| Qube Research & Technologies Ltd | 0.02% | Add +336.8% | 287,293 | $13.3M |
| Penn Capital Management Company, LLC | 1.02% | New | 275,782 | $12.8M |
| PFM Health Sciences, LP | 1.18% | Add +1.9% | 247,893 | $11.5M |
| Rock Springs Capital Management LP | 0.59% | Add +59.9% | 247,053 | $11.4M |
| Susquehanna International Group, LLP | 0.02% | Add +1425.5% | 244,358 | $11.3M |
| Emerald Mutual Fund Advisers Trust | 0.52% | Reduce -38.8% | 232,485 | $10.8M |
| Balyasny Asset Management L.P. | 0.02% | Reduce -65.5% | 227,751 | $10.5M |
| Alyeska Investment Group, L.P. | 0.03% | Add +13.0% | 217,500 | $10.1M |
| BNP Paribas Financial Markets | 0.01% | Add +2524.8% | 212,818 | $9.9M |
| SummitTX Capital, L.P. | 0.30% | Add +59.4% | 211,727 | $9.8M |
| Bank of America Corp. | 0.00% | Add +28.7% | 208,595 | $9.7M |
| Skandinaviska Enskilda Banken AB (publ) | 0.03% | Add +52.7% | 187,475 | $8.7M |
| New York State Common Retirement Fund | 0.01% | Add +1087.9% | 185,317 | $8.6M |
| Clark Capital Management Group, Inc. | 0.05% | New | 180,250 | $8.3M |
| UBS Group AG | 0.00% | Add +7.1% | 169,506 | $7.8M |
| Ally Bridge Group (NY) LLC | 12.35% | Reduce -44.5% | 168,029 | $7.8M |
| Engineers Gate Manager LP | 0.09% | New | 168,005 | $7.8M |
| Barclays PLC | 0.00% | Reduce -7.8% | 157,685 | $7.3M |
| Buckley Capital Advisors, LLC | 6.01% | — | 149,150 | $6.9M |
| Brevan Howard Capital Management LP | 0.14% | Add +936.5% | 147,800 | $6.8M |
| Capital World Investors | 0.00% | Reduce -82.3% | 145,522 | $6.7M |
| Deutsche Bank AG | 0.00% | Add +3.8% | 141,982 | $6.6M |
| Jane Street Group, LLC | 0.01% | New | 141,740 | $6.6M |
| Granahan Investment Management, LLC | 0.27% | Add +25.9% | 137,592 | $6.4M |
| Sphera Funds Management LTD. | 1.32% | Add +227.6% | 136,314 | $6.3M |
| Eagle Health Investments LP | 1.37% | New | 135,100 | $6.3M |
| HighVista Strategies LLC | 1.61% | Add +622.3% | 135,069 | $6.3M |
| Trexquant Investment LP | 0.05% | Add +1185.9% | 132,912 | $6.2M |
| Seven Fleet Capital Management LP | 4.08% | — | 130,079 | $6.0M |
| Royce & Associates LP | 0.06% | Add +316.4% | 129,043 | $6.0M |
| Nan Fung Trinity (hk) Ltd. | 0.45% | No change | 123,850 | $5.7M |
| Frontier Capital Management Co. LLC | 0.06% | Add +1.1% | 119,695 | $5.5M |
| Peregrine Capital Management LLC | 0.17% | Add +28.6% | 119,564 | $5.5M |
| Centiva Capital, LP | 0.33% | New | 118,804 | $5.5M |
| Silverarc Capital Management, LLC | 0.79% | New | 117,485 | $5.4M |
| JPMorgan Chase & Co. | 0.00% | Reduce -71.7% | 115,517 | $5.3M |
| Nuveen, LLC | 0.00% | Add +6.3% | 100,622 | $4.7M |
| Rafferty Asset Management, LLC | 0.02% | Add +3.4% | 95,597 | $4.4M |
| Swiss National Bank | 0.00% | Add +16.2% | 89,100 | $4.1M |
| Mutual of America Capital Management LLC | 0.04% | Add +5.5% | 83,166 | $3.9M |
| State of Wisconsin Investment Board | 0.01% | Add +80.3% | 72,482 | $3.4M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +23.9% | 72,360 | $3.4M |
| National Philanthropic Trust | 0.03% | New | 69,545 | $3.2M |
| Ikarian Capital, LLC | 0.41% | Add +23.0% | 68,823 | $3.2M |
| Sei Investments Co. | 0.00% | Reduce -40.9% | 67,330 | $3.1M |
| Atle Fund Management AB | 0.93% | Add +4.3% | 62,735 | $2.9M |
| KVP Capital Advisors, LP | 2.85% | — | 59,700 | $2.8M |
| AQR Capital Management | 0.00% | Add +58.4% | 58,752 | $2.7M |
| Rhumbline Advisers | 0.00% | Reduce -8.0% | 55,068 | $2.5M |
| Jump Financial, LLC | 0.03% | New | 54,487 | $2.5M |
| DV Trading LLC | 0.22% | — | 54,000 | $2.5M |
| Wells Fargo & Company | 0.00% | Add +72.7% | 52,643 | $2.4M |
| Simplex Trading, LLC | 0.06% | Add +95.6% | 49,108 | $2.3M |
| Lazard Asset Management LLC | 0.00% | Reduce -14.2% | 48,445 | $2.2M |
| Russell Investments Group, Ltd. | 0.00% | Reduce -50.5% | 46,678 | $2.2M |
| Moody Aldrich Partners LLC | 0.40% | Reduce -9.7% | 46,306 | $2.1M |
| WINTON GROUP Ltd | 0.07% | New | 44,200 | $2.0M |
| Boothbay Fund Management, LLC | 0.05% | Add +28.1% | 43,862 | $2.0M |
| Banque Pictet & Cie SA | 0.02% | New | 43,796 | $2.0M |
| Alliancebernstein L.P. | 0.00% | No change | 42,290 | $2.0M |
| Caption Management, LLC | 0.09% | Reduce -88.6% | 42,100 | $1.9M |
| ADAR1 Capital Management, LLC | 0.14% | Add +65.8% | 41,830 | $1.9M |
| Legal & General Group Plc | 0.00% | Add +4.6% | 41,788 | $1.9M |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -50.8% | 41,186 | $1.9M |
| California State Teachers Retirement System | 0.00% | Add +27.5% | 40,717 | $1.9M |
| SG Americas Securities, LLC | 0.00% | Add +171.9% | 40,198 | $1.9M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | Add +9663.9% | 38,958 | $1.8M |
| XTX Topco Ltd | 0.04% | New | 36,294 | $1.7M |
| Profund Advisors LLC | 0.05% | Add +78.3% | 35,371 | $1.6M |
| Militia Capital Partners, LP | 0.61% | New | 35,000 | $1.6M |
| Citigroup Inc. | 0.00% | Add +51.2% | 34,663 | $1.6M |
| Nomura Asset Management International Inc. | 0.00% | — | 33,155 | $1.5M |
| Diametric Capital, LP | 0.39% | Add +319.9% | 31,328 | $1.5M |
| F/m Investments LLC | 0.05% | Reduce -46.4% | 29,871 | $1.4M |
| Los Angeles Capital Management LLC | 0.00% | Reduce -14.2% | 19,669 | $1.4M |
| Jefferies Financial Group Inc. | 0.01% | Add +69.4% | 29,304 | $1.4M |
| Aquatic Capital Management LLC | 0.04% | New | 28,572 | $1.3M |
| Fred Alger Management, LLC | 0.01% | Reduce -0.1% | 28,479 | $1.3M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +12.9% | 27,243 | $1.3M |
| Diadema Partners LP | 0.74% | Reduce -84.8% | 26,892 | $1.2M |
| Y-Intercept (Hong Kong) Ltd | 0.03% | New | 26,685 | $1.2M |
| Erste Asset Management GmbH | 0.01% | No change | 25,600 | $1.2M |
| MetLife Investment Management, LLC | 0.01% | Add +7.5% | 25,761 | $1.2M |
| Prudential Financial Inc. | 0.00% | Add +104.4% | 24,855 | $1.2M |
| Virtu Financial LLC | 0.04% | New | 22,878 | $1.1M |
| Group One Trading LLC | 0.03% | Add +168.3% | 22,530 | $1.0M |
| MIdWestOne Financial Group, Inc. | 0.11% | New | 21,817 | $1.0M |
| Fox Run Management, L.L.C. | 0.16% | Add +464.8% | 21,785 | $1.0M |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +191.0% | 21,075 | $976K |
| Teachers Retirement System of the State of Kentucky | 0.01% | Add +50.6% | 20,941 | $970K |
| AWM Investment Company, Inc. | 0.09% | New | 20,000 | $926K |
| Envestnet Asset Management Inc. | 0.00% | Add +139.4% | 18,975 | $879K |
| TD Asset Management Inc | 0.00% | Reduce -83.6% | 18,622 | $862K |
| Intech Investment Management LLC | 0.01% | Reduce -18.8% | 18,346 | $849K |
| Guggenheim Capital LLC | 0.01% | Add +92.0% | 18,181 | $842K |
| Quantitative Investment Management, LLC | 0.08% | New | 17,581 | $814K |
| Atom Investors LP | 0.06% | New | 17,550 | $813K |
| Walleye Capital LLC | 0.00% | Add +2191.9% | 16,983 | $786K |
| FORA Capital, LLC | 0.10% | New | 16,979 | $786K |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | Add +46.6% | 16,774 | $777K |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 0.00% | Reduce -9.0% | 16,100 | $745K |
| State of New Jersey Common Pension Fund D | 0.00% | Reduce -49.4% | 15,418 | $714K |
| Handelsbanken Fonder AB | 0.00% | Add +11.6% | 15,400 | $713K |
| Man Group plc | 0.00% | Add +30.9% | 15,047 | $697K |
| Oxford Asset Management LLP | 0.25% | New | 15,021 | $695K |
| DNB Asset Management AS | 0.00% | Add +121.2% | 14,071 | $651K |
| Magnetar Financial LLC | 0.01% | New | 13,946 | $646K |
| Natixis | 0.00% | New | 13,840 | $641K |
| Jackson Creek Investment Advisors LLC | 0.19% | Reduce -9.5% | 13,760 | $637K |
| Arizona State Retirement System | 0.00% | Add +8.1% | 12,629 | $585K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +8.9% | 12,572 | $582K |
| Sofinnova Investments, Inc. | 0.02% | Reduce -92.5% | 12,414 | $575K |
| Gotham Asset Management | 0.00% | New | 12,130 | $562K |
| Aspiriant, LLC | 0.02% | No change | 12,128 | $562K |
| AlphaGrep UK Ltd | 0.18% | — | 11,809 | $547K |
| Victory Capital Management Inc. | 0.00% | Reduce -71.8% | 11,732 | $543K |
| Freestone Grove Partners LP | 0.00% | Reduce -79.7% | 10,258 | $475K |
| KLP Kapitalforvaltning As | 0.00% | Add +20.5% | 10,000 | $463K |
| Royal Bank of Canada | 0.00% | Add +2382.3% | 9,656 | $447K |
| Canada Pension Plan Investment Board | 0.00% | New | 9,500 | $440K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 9,041 | $419K |
| Oppenheimer & Co. Inc. | 0.01% | Reduce -1.1% | 8,747 | $405K |
| Brummer Multi-Strategy AB | 2.45% | New | 8,741 | $405K |
| Ameriprise Financial Inc. | 0.00% | Reduce -93.3% | 8,725 | $404K |
| ProShare Advisors LLC | 0.00% | Add +19.3% | 8,522 | $395K |
| Scientech Research LLC | 0.24% | New | 8,126 | $376K |
| Voya Investment Management LLC | 0.00% | Add +11.0% | 8,106 | $375K |
| Glenmede Trust Co. NA | 0.00% | — | 7,789 | $361K |
| LPL Financial LLC | 0.00% | New | 7,720 | $357K |
| Persistent Asset Partners Ltd | 0.17% | Reduce -82.0% | 7,416 | $343K |
| Teacher Retirement System of Texas | 0.00% | Reduce -31.0% | 6,669 | $309K |
| Graham Capital Management, L.P. | 0.02% | Reduce -59.5% | 6,630 | $307K |
| Marshall Wace, LLP | 0.00% | Reduce -96.4% | 6,595 | $305K |
| Integrated Wealth Concepts LLC | 0.00% | New | 6,560 | $304K |
| Walleye Trading LLC | 0.00% | New | 6,521 | $302K |
| Martingale Asset Management L P | 0.01% | Reduce -13.4% | 5,810 | $269K |
| Perbak Capital Partners LLP | 0.08% | Add +11.1% | 5,767 | $267K |
| D. E. Shaw & Co. | 0.00% | Reduce -25.7% | 5,767 | $267K |
| EntryPoint Capital, LLC | 0.10% | New | 5,766 | $267K |
| Prelude Capital Management, LLC | 0.02% | Reduce -67.2% | 5,378 | $249K |
| Virtus Investment Advisers, LLC | 0.06% | Add +260.5% | 5,116 | $237K |
| DLD Asset Management, LP | 0.08% | New | 5,000 | $232K |
| Farallon Capital Management, L.L.C. | 0.00% | Reduce -96.7% | 5,000 | $232K |
| Caxton Associates LLP | 0.00% | New | 4,959 | $230K |
| Creative Planning | 0.00% | Reduce -2.0% | 4,789 | $222K |
| HRT Financial LP | 0.00% | New | 4,784 | $221K |
| MML Investors Services, LLC | 0.00% | New | 4,757 | $220K |
| Shay Capital LLC | 0.03% | New | 4,600 | $213K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 4,435 | $205K |
| Ameritas Investment Partners, Inc. | 0.01% | Add +8.6% | 3,790 | $175K |
| FNY Investment Advisers, LLC | 0.05% | Add +600.0% | 3,500 | $162K |
| Ensign Peak Advisors, Inc | 0.00% | Reduce -98.4% | 3,351 | $155K |
| Avanza Fonder AB | 0.00% | Add +11.3% | 3,195 | $148K |
| Quantbot Technologies LP | 0.00% | Add +216.2% | 3,118 | $144K |
| AlphaQuest LLC | 0.01% | Add +33.8% | 2,408 | $111K |
| Comerica Bank | 0.00% | Reduce -98.6% | 2,330 | $108K |
| Bollard Group LLC | 0.00% | No change | 2,288 | $106K |
| Osaic Holdings, Inc. | 0.00% | Add +25.3% | 1,909 | $88K |
| Amalgamated Bank | 0.00% | Add +65.6% | 1,467 | $68K |
| KBC Group NV | 0.00% | No change | 1,367 | $63K |
| US Bancorp \de | 0.00% | Reduce -41.0% | 1,343 | $62K |
| Caitong International Asset Management Co., Ltd | 0.01% | New | 822 | $38K |
| Global Retirement Partners, LLC | 0.00% | Add +519.0% | 619 | $29K |
| T. Rowe Price Investment Management, Inc. | 0.00% | Reduce -97.8% | 553 | $26K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -5.8% | 508 | $24K |
| State of Wyoming | 0.00% | New | 497 | $23K |
| Richardson Financial Services Inc. | 0.01% | New | 436 | $20K |
| Cwm, LLC | 0.00% | Add +526.6% | 401 | $19K |
| Danske Bank A/S | 0.00% | No change | 400 | $19K |
| Hudson Bay Capital Management LP | 0.00% | Reduce -98.5% | 339 | $16K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -82.0% | 331 | $15K |
| Sterling Capital Management LLC | 0.00% | Add +202.0% | 305 | $14K |
| Optiver Holding B.V. | 0.00% | Reduce -27.1% | 210 | $10K |
| NewEdge Advisors, LLC | 0.00% | No change | 175 | $8K |
| Smartleaf Asset Management LLC | 0.00% | Add +30.5% | 171 | $8K |
| Larson Financial Group LLC | 0.00% | Add +47.8% | 170 | $8K |
| Farther Finance Advisors, LLC | 0.00% | Add +96.4% | 165 | $8K |
| GAMMA Investing LLC | 0.00% | Add +47.7% | 127 | $6K |
| Versant Capital Management, Inc | 0.00% | Reduce -27.8% | 117 | $5K |
| EverSource Wealth Advisors, LLC | 0.00% | Reduce -19.9% | 109 | $5K |
| Pinnacle Wealth Planning Services, Inc. | 0.00% | New | 104 | $5K |
| SBI Securities Co., Ltd. | 0.00% | Add +388.2% | 83 | $4K |
| CIBC Private Wealth Group LLC | 0.00% | New | 62 | $3K |
| Keating Financial Advisory Services, Inc. | 0.00% | — | 54 | $3K |
| J.Safra Asset Management Corp | 0.00% | Add +642.9% | 52 | $2K |
| PNC Financial Services Group, Inc. | 0.00% | Reduce -98.4% | 49 | $2K |
| Arax Advisory Partners | 0.00% | Reduce -33.3% | 46 | $2K |
| Bellevue Asset Management, LLC | 0.00% | New | 31 | $1K |
| Aventura Private Wealth, LLC | 0.00% | No change | 30 | $1K |
| Rothschild Investment LLC | 0.00% | Reduce -27.5% | 29 | $1K |
| Jones Financial Companies LLLP | 0.00% | No change | 28 | $1K |
| Bare Financial Services, Inc | 0.00% | New | 23 | $1K |
| Steward Partners Investment Advisory, LLC | 0.00% | No change | 22 | $1K |
| Assetmark, Inc. | 0.00% | New | 19 | $880 |
| IFP Advisors, Inc | 0.00% | Add +1100.0% | 12 | $556 |
| Allworth Financial LP | 0.00% | Reduce -45.0% | 11 | $510 |
| Signaturefd, LLC | 0.00% | New | 11 | $509 |
| Rockefeller Capital Management L.P. | 0.00% | Reduce -94.6% | 11 | $509 |
| Blue Trust, Inc. | 0.00% | New | 11 | $509 |
| Parkside Financial Bank & Trust | 0.00% | No change | 10 | $463 |
| SJS Investment Consulting Inc. | 0.00% | New | 5 | $232 |
| CoreCap Advisors, LLC | 0.00% | Reduce -42.9% | 4 | $185 |
| Hughes Financial Services, LLC | 0.00% | New | 3 | $139 |
| CENTRAL TRUST Co | 0.00% | New | 2 | $93 |
| Private Trust Co. NA | 0.00% | No change | 2 | $93 |
| Essential Partners LLC | 0.00% | No change | 2 | $93 |
| TFC Financial Management, Inc. | 0.00% | No change | 1 | $47 |
| Stone House Investment Management, LLC | 0.00% | Reduce -96.3% | 1 | $46 |
| Covestor Ltd | 0.00% | No change | 2 | $0 |
"% of holder's portfolio" is SLNO's weight in each manager's 13F, not the share of Soleno Therapeutics Inc. the manager owns.