Spruce BiosciencesSPRB

13F holders, Q4 2024 (December 31)
31holders +1
6new positions
4sold out
1famous investor
$0.42avg. 13F price*

At the end of Q4 2024, 31 institutions reported holding Spruce Biosciences Inc. (SPRB) in their 13F filings, up 1 from Q3 2024. 6 opened new positions and 4 sold out. The largest holders were Carlyle Group Inc. ($1.2M), Rock Springs Capital Management LP ($1.1M) and Acadian Asset Management LLC ($437K). One famous investor held it Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).

Company
Spruce Biosciences Inc.
CUSIP
85209E109
Latest filing quarter
Q2 2025

History

Number of 13F holders

01020304050 Q1 2024: 50Q1 2024Q2 2024: 38Q2 2024Q3 2024: 30Q3 2024Q4 2024: 31Q4 2024Q1 2025: 31Q1 2025Q2 2025: 3Q2 2025

Total Exit/New Position Q3 2024 → Q4 2024

InstitutionsTotal Value
New Positions6$583K
Exits4$234K

All 13F filers, Q3 2024 → Q4 2024: 1,510,436 shares bought and 1,008,188 shares sold, net +502,248 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 31 holders

Carlyle Group Inc. 0.03% No change 2,896,518 $1.2M
Rock Springs Capital Management LP 0.04% No change 2,609,125 $1.1M
Acadian Asset Management LLC 0.00% Reduce -16.9% 1,045,828 $437K
Ikarian Capital, LLC 0.12% New 1,000,000 $420K
Vanguard Group Inc. 0.00% No change 843,844 $354K
Sands Capital Alternatives, LLC 0.07% Reduce -9.1% 715,817 $301K
Renaissance Technologies 0.00% Reduce -33.4% 405,900 $170K
ADAR1 Capital Management, LLC 0.04% No change 403,716 $170K
Boothbay Fund Management, LLC 0.00% New 288,800 $121K
Geode Capital Management, LLC 0.00% Add +4.5% 273,785 $115K
BlackRock, Inc. 0.00% No change 124,734 $52K
UBS Group AG 0.00% Add +661784.6% 86,045 $36K
Northern Trust Corp. 0.00% Add +7.2% 80,308 $34K
Lion Point Capital, LP 0.16% No change 75,000 $32K
State Street Corp. 0.00% Reduce -5.8% 60,700 $25K
Susquehanna International Group, LLP 0.00% New 58,984 $25K
Shay Capital LLC 0.00% No change 38,119 $16K
HRT Financial LP 0.00% New 37,838 $15K
XTX Topco Ltd 0.00% Add +85.8% 35,549 $15K
Bridgeway Capital Management, LLC 0.00% Reduce -12.8% 34,900 $15K
Two Sigma Investments, LP 0.00% Reduce -11.8% 20,616 $9K
Marex Group Ltd 0.00% No change 14,800 $6K
Two Sigma Advisers, LP 0.00% Reduce -49.1% 13,800 $6K
Simplex Trading, LLC 0.00% New 4,857 $2K
Tower Research Capital LLC (TRC) 0.00% Add +2.4% 4,761 $2K
Morgan Stanley 0.00% No change 2,133 $896
Group One Trading LLC 0.00% Reduce -53.9% 1,769 $743
Caldwell Sutter Capital, Inc. 0.00% No change 1,000 $420
Bank of America Corp. 0.00% Reduce -0.5% 222 $93
BNP Paribas Financial Markets 0.00% New 181 $76
JPMorgan Chase & Co. 0.00% Reduce -2.8% 69 $29

"% of holder's portfolio" is SPRB's weight in each manager's 13F, not the share of Spruce Biosciences Inc. the manager owns.