Spruce BiosciencesSPRB

13F holders, Q1 2025 (March 31)
31holders
5new positions
5sold out
1famous investor
$0.29avg. 13F price*

At the end of Q1 2025, 31 institutions reported holding Spruce Biosciences Inc. (SPRB) in their 13F filings, unchanged from Q4 2024. 5 opened new positions and 5 sold out. The largest holders were Carlyle Group Inc. ($840K), Rock Springs Capital Management LP ($757K) and Acadian Asset Management LLC ($301K). One famous investor held it Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).

Company
Spruce Biosciences Inc.
CUSIP
85209E109
Latest filing quarter
Q2 2025

History

Number of 13F holders

01020304050 Q1 2024: 50Q1 2024Q2 2024: 38Q2 2024Q3 2024: 30Q3 2024Q4 2024: 31Q4 2024Q1 2025: 31Q1 2025Q2 2025: 3Q2 2025

Total Exit/New Position Q4 2024 → Q1 2025

InstitutionsTotal Value
New Positions5$44K
Exits5$357K

All 13F filers, Q4 2024 → Q1 2025: 197,220 shares bought and 925,338 shares sold, net −728,118 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 31 holders

Carlyle Group Inc. 0.02% No change 2,896,518 $840K
Rock Springs Capital Management LP 0.04% No change 2,609,125 $757K
Acadian Asset Management LLC 0.00% No change 1,045,828 $301K
Ikarian Capital, LLC 0.09% No change 1,000,000 $290K
Vanguard Group Inc. 0.00% No change 843,844 $245K
ADAR1 Capital Management, LLC 0.02% No change 403,716 $117K
Renaissance Technologies 0.00% Reduce -5.7% 382,900 $111K
Boothbay Fund Management, LLC 0.00% No change 288,800 $84K
Geode Capital Management, LLC 0.00% Add +1.1% 276,708 $80K
BlackRock, Inc. 0.00% No change 124,734 $36K
UBS Group AG 0.00% Add +35.4% 116,464 $34K
Lion Point Capital, LP 0.14% No change 75,000 $22K
State Street Corp. 0.00% No change 60,700 $18K
Two Sigma Securities, LLC 0.00% New 47,686 $14K
XTX Topco Ltd 0.00% Add +15.9% 41,217 $12K
Shay Capital LLC 0.00% No change 38,119 $11K
Virtu Financial LLC 0.00% New 39,426 $11K
Jane Street Group, LLC 0.00% New 37,429 $11K
Northern Trust Corp. 0.00% Reduce -59.3% 32,721 $9K
Two Sigma Investments, LP 0.00% Reduce -0.3% 20,545 $6K
Ground Swell Capital, LLC 0.01% New 17,312 $5K
Marex Group Ltd 0.00% No change 14,800 $4K
Two Sigma Advisers, LP 0.00% Reduce -11.6% 12,200 $4K
Citigroup Inc. 0.00% New 11,083 $3K
Morgan Stanley 0.00% Add +246.7% 7,396 $2K
Tower Research Capital LLC (TRC) 0.00% Reduce -1.3% 4,697 $1K
Group One Trading LLC 0.00% Reduce -34.8% 1,153 $334
Caldwell Sutter Capital, Inc. 0.00% No change 1,000 $290
Bank of America Corp. 0.00% Add +5.0% 233 $68
BNP Paribas Financial Markets 0.00% No change 181 $52
JPMorgan Chase & Co. 0.00% Reduce -5.8% 65 $19

"% of holder's portfolio" is SPRB's weight in each manager's 13F, not the share of Spruce Biosciences Inc. the manager owns.