Stoke TherapeuticsSTOK
13F holders, Q4 2025 (December 31)183holders +32
42new positions
12sold out
5famous investors
$31.74avg. 13F price*
At the end of Q4 2025, 183 institutions reported holding Stoke Therapeutics Inc. (STOK) in their 13F filings, up 32 from Q3 2025. 42 opened new positions and 12 sold out. The largest holders were FMR LLC ($177.8M), RTW Investments, LP ($176.1M) and Lynx1 Capital Management LP ($171.5M). 5 famous investors held it, including Steve Cohen (0.1% of Point72 Asset Management's portfolio), Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio) and David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio).
- Company
- Stoke Therapeutics Inc.
- CUSIP
- 86150R107
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 42 | $104.8M |
| Exits | 12 | $27.4M |
All 13F filers, Q3 2025 → Q4 2025: 8,264,908 shares bought and 6,720,921 shares sold, net +1,543,987 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 183 holders
| FMR LLC | 0.01% | Reduce -18.4% | 5,600,920 | $177.8M |
| RTW Investments, LP | 1.76% | Add +8.3% | 5,546,856 | $176.1M |
| Lynx1 Capital Management LP | 34.73% | No change | 5,404,674 | $171.5M |
| BlackRock, Inc. | 0.00% | Reduce -12.9% | 5,212,554 | $165.4M |
| Redmile Group, LLC | 9.43% | Reduce -3.4% | 4,034,070 | $128.0M |
| Morgan Stanley | 0.01% | Add +0.3% | 3,546,158 | $112.6M |
| Baker Bros. Advisors LP | 0.62% | Reduce -28.0% | 3,336,697 | $105.9M |
| Toronto Dominion Bank | 0.18% | No change | 3,173,258 | $100.7M |
| Vanguard Group Inc. | 0.00% | Reduce -0.5% | 3,149,239 | $100.0M |
| State Street Corp. | 0.00% | Add +75.2% | 2,498,049 | $79.3M |
| BVF Inc. | 2.42% | Add +36.7% | 2,265,674 | $71.9M |
| Siren, L.L.C. | 2.13% | No change | 2,247,347 | $71.3M |
| Deerfield Management Company, L.P. | 0.85% | New | 1,823,500 | $57.9M |
| Janus Henderson Group PLC | 0.02% | Add +333.8% | 1,450,933 | $46.0M |
| Polar Capital Holdings Plc | 0.18% | Reduce -4.1% | 1,269,131 | $40.3M |
| Assenagon Asset Management S.A. | 0.06% | Add +36.4% | 1,227,723 | $39.0M |
| Point72 Asset Management | 0.06% | Reduce -6.5% | 1,222,213 | $38.8M |
| Geode Capital Management, LLC | 0.00% | Add +1.7% | 1,166,145 | $37.0M |
| Goldman Sachs Group Inc. | 0.01% | Reduce -0.7% | 1,142,737 | $36.3M |
| Dimensional Fund Advisors LP | 0.01% | Add +21.9% | 827,139 | $26.3M |
| MPM Bioimpact LLC | 2.80% | Reduce -2.5% | 770,289 | $24.4M |
| Wellington Management Group LLP | 0.00% | Reduce -0.3% | 735,799 | $23.4M |
| Opaleye Management Inc. | 2.91% | Add +1.9% | 695,000 | $22.1M |
| Tang Capital Management LLC | 0.78% | No change | 500,000 | $15.9M |
| Candriam S.C.A. | 0.07% | New | 446,690 | $14.2M |
| Parkman Healthcare Partners LLC | 1.30% | Add +72.1% | 430,155 | $13.7M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +2.0% | 410,906 | $13.0M |
| Northern Trust Corp. | 0.00% | Reduce -2.8% | 403,168 | $12.8M |
| Erste Asset Management GmbH | 0.11% | No change | 396,000 | $12.6M |
| T. Rowe Price Associates Inc. | 0.00% | Add +626.3% | 372,334 | $11.8M |
| JPMorgan Chase & Co. | 0.00% | Add +1040.2% | 277,930 | $8.8M |
| Birchview Capital, LP | 4.83% | Add +23.8% | 260,000 | $8.3M |
| Invesco Ltd. | 0.00% | Add +24.7% | 259,543 | $8.2M |
| Baillie Gifford & Co. | 0.01% | New | 246,900 | $7.8M |
| Rhenman & Partners Asset Management AB | 0.64% | Reduce -13.6% | 216,000 | $6.9M |
| Bank of America Corp. | 0.00% | Reduce -17.4% | 206,164 | $6.5M |
| Granahan Investment Management, LLC | 0.26% | Reduce -24.6% | 191,397 | $6.1M |
| UBS Group AG | 0.00% | Reduce -44.5% | 169,713 | $5.4M |
| First Trust Advisors LP | 0.00% | Add +6.8% | 162,679 | $5.2M |
| Barclays PLC | 0.00% | Add +40.1% | 150,945 | $4.8M |
| Bank of New York Mellon Corp | 0.00% | Add +16.9% | 140,802 | $4.5M |
| Franklin Resources Inc. | 0.00% | Add +14.2% | 132,222 | $4.2M |
| Susquehanna Portfolio Strategies, LLC | 0.06% | No change | 126,350 | $4.0M |
| Gilder Gagnon Howe & Co. LLC | 0.04% | Reduce -21.1% | 122,448 | $3.9M |
| Informed Momentum Co LLC | 0.42% | Reduce -2.0% | 117,823 | $3.7M |
| HighVista Strategies LLC | 0.94% | New | 115,539 | $3.7M |
| American Century Companies Inc. | 0.00% | Add +16.2% | 115,118 | $3.7M |
| DAFNA Capital Management LLC | 0.81% | Reduce -35.9% | 108,875 | $3.5M |
| Nuveen, LLC | 0.00% | Reduce -1.6% | 104,261 | $3.3M |
| Rafferty Asset Management, LLC | 0.01% | Add +155.3% | 90,193 | $2.9M |
| Penserra Capital Management LLC | 0.03% | Reduce -41.2% | 88,507 | $2.8M |
| Quantedge Capital Pte Ltd | 1.32% | Add +118.0% | 87,200 | $2.8M |
| Swiss National Bank | 0.00% | Add +2.2% | 75,700 | $2.4M |
| Alyeska Investment Group, L.P. | 0.01% | New | 75,000 | $2.4M |
| Palo Alto Investors LP | 0.32% | Reduce -31.7% | 72,022 | $2.3M |
| Principal Financial Group Inc. | 0.00% | Add +55.5% | 70,282 | $2.2M |
| Jane Street Group, LLC | 0.00% | New | 67,112 | $2.1M |
| Alps Advisors Inc. | 0.01% | Add +48.9% | 66,502 | $2.1M |
| Schonfeld Strategic Advisors LLC | 0.01% | Reduce -73.5% | 63,109 | $2.0M |
| Hussman Strategic Advisors, Inc. | 0.48% | New | 63,000 | $2.0M |
| Rhumbline Advisers | 0.00% | Reduce -8.6% | 62,414 | $2.0M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -24.6% | 57,212 | $1.8M |
| Privium Fund Management B.V. | 0.32% | New | 55,000 | $1.7M |
| Woodline Partners LP | 0.01% | Reduce -47.3% | 50,120 | $1.6M |
| D. E. Shaw & Co. | 0.00% | Reduce -5.2% | 49,901 | $1.6M |
| Wells Fargo & Company | 0.00% | Add +76.6% | 49,585 | $1.6M |
| Susquehanna International Group, LLP | 0.00% | Add +71.8% | 46,022 | $1.5M |
| Nomura Holdings Inc. | 0.00% | Reduce -45.4% | 44,352 | $1.4M |
| Creative Planning | 0.00% | Reduce -3.7% | 41,712 | $1.3M |
| Victory Capital Management Inc. | 0.00% | New | 41,140 | $1.3M |
| Platinum Investment Management Ltd. | 0.30% | Add +24.1% | 40,815 | $1.3M |
| Alliancebernstein L.P. | 0.00% | No change | 40,630 | $1.3M |
| Kennondale Capital Management LLC | 0.90% | Reduce -44.5% | 38,731 | $1.2M |
| Harvest Investment Services, LLC | 0.23% | New | 38,347 | $1.2M |
| California State Teachers Retirement System | 0.00% | Add +15.8% | 37,127 | $1.2M |
| Legal & General Group Plc | 0.00% | Reduce -3.8% | 36,366 | $1.2M |
| Canada Pension Plan Investment Board | 0.00% | New | 35,200 | $1.1M |
| Deutsche Bank AG | 0.00% | Add +37.9% | 33,406 | $1.1M |
| Profund Advisors LLC | 0.03% | New | 33,388 | $1.1M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -35.6% | 32,515 | $1.0M |
| AQR Capital Management | 0.00% | Add +1.2% | 29,467 | $935K |
| Readystate Asset Management LP | 0.07% | New | 29,059 | $922K |
| Cresset Asset Management, LLC | 0.00% | Reduce -1.5% | 26,325 | $836K |
| SG Americas Securities, LLC | 0.00% | Add +187.2% | 25,836 | $820K |
| MetLife Investment Management, LLC | 0.00% | No change | 25,320 | $804K |
| Allspring Global Investments Holdings, LLC | 0.00% | Reduce -30.2% | 24,462 | $756K |
| Ameriprise Financial Inc. | 0.00% | Add +0.4% | 21,076 | $669K |
| Tudor Investment Corporation | 0.00% | New | 19,309 | $613K |
| Massachusetts Financial Services Co. | 0.00% | New | 19,101 | $606K |
| Intech Investment Management LLC | 0.01% | Add +41.9% | 18,652 | $592K |
| Diadema Partners LP | 0.32% | New | 17,181 | $545K |
| Sei Investments Co. | 0.00% | Add +1.1% | 16,631 | $528K |
| PSP Research LLC | 0.46% | — | 16,621 | $528K |
| Aviva PLC | 0.00% | Reduce -28.9% | 15,871 | $504K |
| Citadel Advisors | 0.00% | Reduce -78.6% | 15,851 | $503K |
| AlphaQuest LLC | 0.03% | Reduce -0.4% | 15,036 | $477K |
| New York State Common Retirement Fund | 0.00% | No change | 15,035 | $477K |
| State of Wisconsin Investment Board | 0.00% | New | 14,819 | $470K |
| CANADA LIFE ASSURANCE Co | 0.00% | Add +23.3% | 14,768 | $469K |
| Simplex Trading, LLC | 0.01% | New | 14,281 | $453K |
"% of holder's portfolio" is STOK's weight in each manager's 13F, not the share of Stoke Therapeutics Inc. the manager owns.