Stoke TherapeuticsSTOK
13F holders, Q4 2025 (December 31)183holders +32
42new positions
12sold out
5famous investors
$31.74avg. 13F price*
At the end of Q4 2025, 183 institutions reported holding Stoke Therapeutics Inc. (STOK) in their 13F filings, up 32 from Q3 2025. 42 opened new positions and 12 sold out. The largest holders were FMR LLC ($177.8M), RTW Investments, LP ($176.1M) and Lynx1 Capital Management LP ($171.5M). 5 famous investors held it, including Steve Cohen (0.1% of Point72 Asset Management's portfolio), Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio) and David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio).
- Company
- Stoke Therapeutics Inc.
- CUSIP
- 86150R107
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 42 | $104.8M |
| Exits | 12 | $27.4M |
All 13F filers, Q3 2025 → Q4 2025: 8,264,908 shares bought and 6,720,921 shares sold, net +1,543,987 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 183 holders
| FMR LLC | 0.01% | Reduce -18.4% | 5,600,920 | $177.8M |
| RTW Investments, LP | 1.76% | Add +8.3% | 5,546,856 | $176.1M |
| Lynx1 Capital Management LP | 34.73% | No change | 5,404,674 | $171.5M |
| BlackRock, Inc. | 0.00% | Reduce -12.9% | 5,212,554 | $165.4M |
| Redmile Group, LLC | 9.43% | Reduce -3.4% | 4,034,070 | $128.0M |
| Morgan Stanley | 0.01% | Add +0.3% | 3,546,158 | $112.6M |
| Baker Bros. Advisors LP | 0.62% | Reduce -28.0% | 3,336,697 | $105.9M |
| Toronto Dominion Bank | 0.18% | No change | 3,173,258 | $100.7M |
| Vanguard Group Inc. | 0.00% | Reduce -0.5% | 3,149,239 | $100.0M |
| State Street Corp. | 0.00% | Add +75.2% | 2,498,049 | $79.3M |
| BVF Inc. | 2.42% | Add +36.7% | 2,265,674 | $71.9M |
| Siren, L.L.C. | 2.13% | No change | 2,247,347 | $71.3M |
| Deerfield Management Company, L.P. | 0.85% | New | 1,823,500 | $57.9M |
| Janus Henderson Group PLC | 0.02% | Add +333.8% | 1,450,933 | $46.0M |
| Polar Capital Holdings Plc | 0.18% | Reduce -4.1% | 1,269,131 | $40.3M |
| Assenagon Asset Management S.A. | 0.06% | Add +36.4% | 1,227,723 | $39.0M |
| Point72 Asset Management | 0.06% | Reduce -6.5% | 1,222,213 | $38.8M |
| Geode Capital Management, LLC | 0.00% | Add +1.7% | 1,166,145 | $37.0M |
| Goldman Sachs Group Inc. | 0.01% | Reduce -0.7% | 1,142,737 | $36.3M |
| Dimensional Fund Advisors LP | 0.01% | Add +21.9% | 827,139 | $26.3M |
| MPM Bioimpact LLC | 2.80% | Reduce -2.5% | 770,289 | $24.4M |
| Wellington Management Group LLP | 0.00% | Reduce -0.3% | 735,799 | $23.4M |
| Opaleye Management Inc. | 2.91% | Add +1.9% | 695,000 | $22.1M |
| Tang Capital Management LLC | 0.78% | No change | 500,000 | $15.9M |
| Candriam S.C.A. | 0.07% | New | 446,690 | $14.2M |
| Parkman Healthcare Partners LLC | 1.30% | Add +72.1% | 430,155 | $13.7M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +2.0% | 410,906 | $13.0M |
| Northern Trust Corp. | 0.00% | Reduce -2.8% | 403,168 | $12.8M |
| Erste Asset Management GmbH | 0.11% | No change | 396,000 | $12.6M |
| T. Rowe Price Associates Inc. | 0.00% | Add +626.3% | 372,334 | $11.8M |
| JPMorgan Chase & Co. | 0.00% | Add +1040.2% | 277,930 | $8.8M |
| Birchview Capital, LP | 4.83% | Add +23.8% | 260,000 | $8.3M |
| Invesco Ltd. | 0.00% | Add +24.7% | 259,543 | $8.2M |
| Baillie Gifford & Co. | 0.01% | New | 246,900 | $7.8M |
| Rhenman & Partners Asset Management AB | 0.64% | Reduce -13.6% | 216,000 | $6.9M |
| Bank of America Corp. | 0.00% | Reduce -17.4% | 206,164 | $6.5M |
| Granahan Investment Management, LLC | 0.26% | Reduce -24.6% | 191,397 | $6.1M |
| UBS Group AG | 0.00% | Reduce -44.5% | 169,713 | $5.4M |
| First Trust Advisors LP | 0.00% | Add +6.8% | 162,679 | $5.2M |
| Barclays PLC | 0.00% | Add +40.1% | 150,945 | $4.8M |
| Bank of New York Mellon Corp | 0.00% | Add +16.9% | 140,802 | $4.5M |
| Franklin Resources Inc. | 0.00% | Add +14.2% | 132,222 | $4.2M |
| Susquehanna Portfolio Strategies, LLC | 0.06% | No change | 126,350 | $4.0M |
| Gilder Gagnon Howe & Co. LLC | 0.04% | Reduce -21.1% | 122,448 | $3.9M |
| Informed Momentum Co LLC | 0.42% | Reduce -2.0% | 117,823 | $3.7M |
| HighVista Strategies LLC | 0.94% | New | 115,539 | $3.7M |
| American Century Companies Inc. | 0.00% | Add +16.2% | 115,118 | $3.7M |
| DAFNA Capital Management LLC | 0.81% | Reduce -35.9% | 108,875 | $3.5M |
| Nuveen, LLC | 0.00% | Reduce -1.6% | 104,261 | $3.3M |
| Rafferty Asset Management, LLC | 0.01% | Add +155.3% | 90,193 | $2.9M |
| Penserra Capital Management LLC | 0.03% | Reduce -41.2% | 88,507 | $2.8M |
| Quantedge Capital Pte Ltd | 1.32% | Add +118.0% | 87,200 | $2.8M |
| Swiss National Bank | 0.00% | Add +2.2% | 75,700 | $2.4M |
| Alyeska Investment Group, L.P. | 0.01% | New | 75,000 | $2.4M |
| Palo Alto Investors LP | 0.32% | Reduce -31.7% | 72,022 | $2.3M |
| Principal Financial Group Inc. | 0.00% | Add +55.5% | 70,282 | $2.2M |
| Jane Street Group, LLC | 0.00% | New | 67,112 | $2.1M |
| Alps Advisors Inc. | 0.01% | Add +48.9% | 66,502 | $2.1M |
| Schonfeld Strategic Advisors LLC | 0.01% | Reduce -73.5% | 63,109 | $2.0M |
| Hussman Strategic Advisors, Inc. | 0.48% | New | 63,000 | $2.0M |
| Rhumbline Advisers | 0.00% | Reduce -8.6% | 62,414 | $2.0M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -24.6% | 57,212 | $1.8M |
| Privium Fund Management B.V. | 0.32% | New | 55,000 | $1.7M |
| Woodline Partners LP | 0.01% | Reduce -47.3% | 50,120 | $1.6M |
| D. E. Shaw & Co. | 0.00% | Reduce -5.2% | 49,901 | $1.6M |
| Wells Fargo & Company | 0.00% | Add +76.6% | 49,585 | $1.6M |
| Susquehanna International Group, LLP | 0.00% | Add +71.8% | 46,022 | $1.5M |
| Nomura Holdings Inc. | 0.00% | Reduce -45.4% | 44,352 | $1.4M |
| Creative Planning | 0.00% | Reduce -3.7% | 41,712 | $1.3M |
| Victory Capital Management Inc. | 0.00% | New | 41,140 | $1.3M |
| Platinum Investment Management Ltd. | 0.30% | Add +24.1% | 40,815 | $1.3M |
| Alliancebernstein L.P. | 0.00% | No change | 40,630 | $1.3M |
| Kennondale Capital Management LLC | 0.90% | Reduce -44.5% | 38,731 | $1.2M |
| Harvest Investment Services, LLC | 0.23% | New | 38,347 | $1.2M |
| California State Teachers Retirement System | 0.00% | Add +15.8% | 37,127 | $1.2M |
| Legal & General Group Plc | 0.00% | Reduce -3.8% | 36,366 | $1.2M |
| Canada Pension Plan Investment Board | 0.00% | New | 35,200 | $1.1M |
| Deutsche Bank AG | 0.00% | Add +37.9% | 33,406 | $1.1M |
| Profund Advisors LLC | 0.03% | New | 33,388 | $1.1M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -35.6% | 32,515 | $1.0M |
| AQR Capital Management | 0.00% | Add +1.2% | 29,467 | $935K |
| Readystate Asset Management LP | 0.07% | New | 29,059 | $922K |
| Cresset Asset Management, LLC | 0.00% | Reduce -1.5% | 26,325 | $836K |
| SG Americas Securities, LLC | 0.00% | Add +187.2% | 25,836 | $820K |
| MetLife Investment Management, LLC | 0.00% | No change | 25,320 | $804K |
| Allspring Global Investments Holdings, LLC | 0.00% | Reduce -30.2% | 24,462 | $756K |
| Ameriprise Financial Inc. | 0.00% | Add +0.4% | 21,076 | $669K |
| Tudor Investment Corporation | 0.00% | New | 19,309 | $613K |
| Massachusetts Financial Services Co. | 0.00% | New | 19,101 | $606K |
| Intech Investment Management LLC | 0.01% | Add +41.9% | 18,652 | $592K |
| Diadema Partners LP | 0.32% | New | 17,181 | $545K |
| Sei Investments Co. | 0.00% | Add +1.1% | 16,631 | $528K |
| PSP Research LLC | 0.46% | — | 16,621 | $528K |
| Aviva PLC | 0.00% | Reduce -28.9% | 15,871 | $504K |
| Citadel Advisors | 0.00% | Reduce -78.6% | 15,851 | $503K |
| AlphaQuest LLC | 0.03% | Reduce -0.4% | 15,036 | $477K |
| New York State Common Retirement Fund | 0.00% | No change | 15,035 | $477K |
| State of Wisconsin Investment Board | 0.00% | New | 14,819 | $470K |
| CANADA LIFE ASSURANCE Co | 0.00% | Add +23.3% | 14,768 | $469K |
| Simplex Trading, LLC | 0.01% | New | 14,281 | $453K |
| Acadian Asset Management LLC | 0.00% | New | 14,134 | $447K |
| Citigroup Inc. | 0.00% | Add +108.8% | 13,603 | $432K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -9.9% | 13,550 | $430K |
| Campbell & CO Investment Adviser LLC | 0.02% | Reduce -57.3% | 12,995 | $412K |
| China Universal Asset Management Co., Ltd. | 0.03% | Add +34.4% | 12,907 | $410K |
| Jacobs Levy Equity Management, Inc. | 0.00% | Reduce -14.6% | 12,878 | $409K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +0.9% | 12,535 | $398K |
| Entropy Technologies, LP | 0.02% | New | 11,764 | $373K |
| Capital Fund Management S.A. | 0.00% | New | 11,717 | $372K |
| Quantinno Capital Management LP | 0.00% | New | 11,088 | $352K |
| Arizona State Retirement System | 0.00% | Reduce -3.2% | 10,936 | $347K |
| Dorsey & Whitney Trust CO LLC | 0.02% | No change | 10,815 | $343K |
| ProShare Advisors LLC | 0.00% | Add +11.4% | 10,721 | $340K |
| NewEdge Advisors, LLC | 0.00% | New | 10,403 | $330K |
| Osaic Holdings, Inc. | 0.00% | Add +0.5% | 10,260 | $326K |
| Vestcor Inc | 0.01% | No change | 10,171 | $323K |
| Balyasny Asset Management L.P. | 0.00% | New | 9,340 | $296K |
| Los Angeles Capital Management LLC | 0.00% | Reduce -0.6% | 9,206 | $292K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | No change | 9,129 | $290K |
| Bank of Montreal | 0.00% | New | 9,055 | $287K |
| Farallon Capital Management, L.L.C. | 0.00% | New | 9,000 | $286K |
| Tidal Investments LLC | 0.00% | New | 8,355 | $265K |
| Virtus Investment Advisers, LLC | 0.07% | Reduce -14.7% | 8,214 | $261K |
| KLP Kapitalforvaltning As | 0.00% | Reduce -14.6% | 8,200 | $260K |
| Dynamic Technology Lab Private Ltd | 0.06% | Reduce -40.9% | 8,054 | $256K |
| Voya Investment Management LLC | 0.00% | New | 7,761 | $246K |
| LPL Financial LLC | 0.00% | New | 7,380 | $234K |
| Gsa Capital Partners LLP | 0.02% | Reduce -85.1% | 7,076 | $225K |
| STRS Ohio | 0.00% | Add +9.4% | 7,000 | $222K |
| J. Goldman & Co LP | 0.01% | New | 6,827 | $217K |
| Swiss Life Asset Management Ltd | 0.00% | New | 6,798 | $216K |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 0.00% | New | 6,550 | $208K |
| Prelude Capital Management, LLC | 0.01% | New | 6,369 | $202K |
| Persistent Asset Partners Ltd | 0.07% | New | 4,576 | $145K |
| BNP Paribas Financial Markets | 0.00% | Reduce -68.2% | 4,257 | $135K |
| Group One Trading LLC | 0.00% | New | 4,110 | $130K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 3,748 | $119K |
| Russell Investments Group, Ltd. | 0.00% | Reduce -5.6% | 3,617 | $115K |
| Cygnus Capital Advisors, LLC | 0.07% | — | 3,000 | $95K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +31.1% | 2,776 | $88K |
| Jones Financial Companies LLLP | 0.00% | Reduce -22.1% | 2,570 | $82K |
| Generali Investments, Management Co LLC | 0.02% | Add +41.0% | 2,471 | $78K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -10.8% | 2,436 | $77K |
| CFG Wealth Management Services, Inc. | 0.07% | — | 2,230 | $71K |
| Royal Bank of Canada | 0.00% | Reduce -99.8% | 1,623 | $52K |
| Versant Capital Management, Inc | 0.01% | No change | 1,592 | $51K |
| Amalgamated Bank | 0.00% | Add +13.6% | 1,409 | $45K |
| Harbour Investments, Inc. | 0.00% | Add +312.9% | 1,185 | $38K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -4.9% | 1,121 | $36K |
| State of Wyoming | 0.00% | Reduce -85.8% | 1,110 | $35K |
| GAMMA Investing LLC | 0.00% | Add +22.1% | 830 | $26K |
| Kestra Advisory Services, LLC | 0.00% | New | 818 | $26K |
| Valley National Advisers Inc. | 0.00% | No change | 750 | $23K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -45.7% | 630 | $20K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +3558.8% | 622 | $20K |
| Cwm, LLC | 0.00% | Add +3.1% | 565 | $18K |
| Stone House Investment Management, LLC | 0.00% | No change | 500 | $16K |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | Add +50.2% | 476 | $15K |
| Montag A & Associates Inc. | 0.00% | No change | 440 | $14K |
| Wilmington Savings Fund Society, FSB | 0.00% | No change | 400 | $13K |
| Sterling Capital Management LLC | 0.00% | Add +173.4% | 298 | $9K |
| Rothschild Investment LLC | 0.00% | Add +1.0% | 293 | $9K |
| US Bancorp \de | 0.00% | No change | 244 | $8K |
| Prestige Wealth Management Group LLC | 0.00% | New | 200 | $6K |
| Daiwa Securities Group Inc. | 0.00% | No change | 175 | $6K |
| Smartleaf Asset Management LLC | 0.00% | New | 155 | $5K |
| Optiver Holding B.V. | 0.00% | Reduce -59.9% | 142 | $5K |
| Rockefeller Capital Management L.P. | 0.00% | New | 98 | $3K |
| J.Safra Asset Management Corp | 0.00% | Reduce -27.6% | 97 | $3K |
| Larson Financial Group LLC | 0.00% | Reduce -19.3% | 92 | $3K |
| Quantbot Technologies LP | 0.00% | New | 88 | $3K |
| Signaturefd, LLC | 0.00% | No change | 83 | $3K |
| PNC Financial Services Group, Inc. | 0.00% | No change | 44 | $1K |
| Rachor Investment Advisory Services, LLC | 0.00% | — | 40 | $1K |
| Global Retirement Partners, LLC | 0.00% | No change | 35 | $1K |
| Arax Advisory Partners | 0.00% | Reduce -88.1% | 21 | $667 |
| Farther Finance Advisors, LLC | 0.00% | Add +5.9% | 18 | $571 |
| Parallel Advisors, LLC | 0.00% | New | 13 | $413 |
| Allworth Financial LP | 0.00% | Add +250.0% | 7 | $223 |
| Root Financial Partners, LLC | 0.00% | New | 7 | $222 |
| IFP Advisors, Inc | 0.00% | No change | 5 | $159 |
| SBI Securities Co., Ltd. | 0.00% | Reduce -91.1% | 5 | $159 |
| True Wealth Design, LLC | 0.00% | No change | 4 | $127 |
"% of holder's portfolio" is STOK's weight in each manager's 13F, not the share of Stoke Therapeutics Inc. the manager owns.