TalpheraTLPH
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 38 institutions reported holding Talphera Inc. (TLPH) in their 13F filings, up 4 from Q3 2025. 9 opened new positions and 6 sold out. The largest holders were AIGH Capital Management LLC ($5.3M), Rock Springs Capital Management LP ($4.1M) and Rosalind Advisors, Inc. ($4.1M). 2 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Talphera Inc.
- CUSIP
- 00444T209
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 9 | $1.2M |
| Exits | 6 | $40K |
All 13F filers, Q3 2025 → Q4 2025: 2,649,363 shares bought and 892,913 shares sold, net +1,756,450 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 38 holders
| AIGH Capital Management LLC | 1.57% | Add +4.7% | 4,661,502 | $5.3M |
| Rock Springs Capital Management LP | 0.21% | No change | 3,589,186 | $4.1M |
| Rosalind Advisors, Inc. | 1.49% | Reduce -18.4% | 3,579,273 | $4.1M |
| Nantahala Capital Management, LLC | 0.24% | No change | 3,492,519 | $4.0M |
| Empery Asset Management, LP | 1.35% | — | 1,333,497 | $1.5M |
| Bleichroeder LP | 0.18% | No change | 881,166 | $1.0M |
| Vanguard Group Inc. | 0.00% | Add +131.9% | 663,677 | $757K |
| Dauntless Investment Group, LLC | 2.43% | Add +479.3% | 579,320 | $660K |
| Cantor Fitzgerald, L. P. | 0.02% | New | 577,490 | $658K |
| Geode Capital Management, LLC | 0.00% | Add +107.0% | 342,987 | $391K |
| Renaissance Technologies | 0.00% | Add +412.6% | 257,380 | $293K |
| Diadema Partners LP | 0.09% | New | 136,923 | $156K |
| BlackRock, Inc. | 0.00% | No change | 91,548 | $104K |
| Simplex Trading, LLC | 0.00% | Add +6892.6% | 85,799 | $98K |
| Jane Street Group, LLC | 0.00% | New | 84,938 | $97K |
| Values First Advisors, Inc. | 0.05% | Reduce -17.0% | 81,208 | $93K |
| Citadel Advisors | 0.00% | New | 76,445 | $87K |
| Mariner, LLC | 0.00% | Add +132.0% | 58,000 | $66K |
| Group One Trading LLC | 0.00% | Add +88.0% | 57,173 | $65K |
| Susquehanna International Group, LLP | 0.00% | New | 56,432 | $64K |
| Northern Trust Corp. | 0.00% | Add +382.8% | 52,580 | $60K |
| Persistent Asset Partners Ltd | 0.02% | New | 36,630 | $42K |
| Two Sigma Investments, LP | 0.00% | New | 24,588 | $28K |
| State Street Corp. | 0.00% | No change | 22,182 | $25K |
| Gsa Capital Partners LLP | 0.00% | New | 20,973 | $24K |
| Onyx Bridge Wealth Group LLC | 0.00% | No change | 11,500 | $13K |
| UBS Group AG | 0.00% | Reduce -75.3% | 6,818 | $8K |
| MAI Capital Management | 0.00% | No change | 3,314 | $4K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -54.5% | 2,801 | $3K |
| Wells Fargo & Company | 0.00% | Add +103.5% | 983 | $1K |
| Bank of America Corp. | 0.00% | Add +90.3% | 335 | $382 |
| Silicon Valley Capital Partners | 0.00% | No change | 137 | $156 |
| BNP Paribas Financial Markets | 0.00% | No change | 136 | $155 |
| Arax Advisory Partners | 0.00% | New | 81 | $92 |
| SBI Securities Co., Ltd. | 0.00% | Reduce -69.2% | 78 | $89 |
| Global Retirement Partners, LLC | 0.00% | Reduce -68.5% | 23 | $26 |
| Morgan Stanley | 0.00% | No change | 10 | $11 |
| Dogwood Wealth Management LLC | 0.00% | No change | 10 | $11 |
"% of holder's portfolio" is TLPH's weight in each manager's 13F, not the share of Talphera Inc. the manager owns.