Xilio TherapeuticsXLO

13F holders, Q3 2025 (September 30)
36holders +1
4new positions
3sold out
1famous investor
$0.84avg. 13F price*

At the end of Q3 2025, 36 institutions reported holding Xilio Therapeutics Inc. (XLO) in their 13F filings, up 1 from Q2 2025. 4 opened new positions and 3 sold out. The largest holders were Gilead Sciences, Inc. ($7.7M), Bain Capital Life Sciences Investors, LLC ($3.8M) and Merck & Co., Inc. ($1.3M). One famous investor held it Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).

Company
Xilio Therapeutics Inc.
CUSIP
98422T100
Latest filing quarter
Q2 2026

History

Number of 13F holders

010203040 Q1 2024: 31Q1 2024Q2 2024: 32Q2 2024Q3 2024: 33Q3 2024Q4 2024: 35Q4 2024Q1 2025: 35Q1 2025Q2 2025: 35Q2 2025Q3 2025: 36Q3 2025Q4 2025: 37Q4 2025Q1 2026: 1Q1 2026Q2 2026: 1Q2 2026

Total Exit/New Position Q2 2025 → Q3 2025

InstitutionsTotal Value
New Positions4$72K
Exits3$1.0M

All 13F filers, Q2 2025 → Q3 2025: 496,902 shares bought and 2,240,249 shares sold, net −1,743,347 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 36 holders

Gilead Sciences, Inc. 0.43% No change 9,105,451 $7.7M
Bain Capital Life Sciences Investors, LLC 0.26% No change 4,566,817 $3.8M
Merck & Co., Inc. 0.55% No change 1,483,758 $1.3M
Takeda Pharmaceutical Co. Ltd. 7.59% No change 1,475,121 $1.2M
Vanguard Group Inc. 0.00% Add +9.1% 1,255,692 $1.1M
Morgan Stanley 0.00% Reduce -33.4% 961,917 $811K
AJU IB Investment Co., Ltd. 0.52% No change 667,742 $596K
FMR LLC 0.00% No change 511,820 $431K
Geode Capital Management, LLC 0.00% Reduce -11.0% 328,972 $277K
Squarepoint Ops LLC 0.00% Add +39.6% 328,794 $277K
Trustees of Columbia University in the City of New York 0.03% No change 249,635 $210K
Renaissance Technologies 0.00% Add +24.7% 204,700 $173K
Balyasny Asset Management L.P. 0.00% No change 198,859 $168K
State Street Corp. 0.00% Add +277.7% 163,890 $138K
Two Sigma Investments, LP 0.00% Add +12.5% 87,790 $74K
XTX Topco Ltd 0.00% Add +119.0% 76,045 $64K
Northern Trust Corp. 0.00% No change 66,609 $56K
Bridgeway Capital Management, LLC 0.00% No change 56,081 $47K
Two Sigma Securities, LLC 0.00% New 32,130 $27K
LPL Financial LLC 0.00% No change 31,000 $26K
Two Sigma Advisers, LP 0.00% New 29,689 $25K
Aptus Capital Advisors, LLC 0.00% No change 25,000 $21K
Mariner, LLC 0.00% No change 25,000 $21K
HRT Financial LP 0.00% New 24,736 $20K
SevenBridge Financial Group, LLC 0.00% No change 25,000 $19K
Raymond James Financial Inc. 0.00% No change 18,761 $16K
UBS Group AG 0.00% Reduce -94.3% 13,652 $12K
Dunhill Financial, LLC 0.00% No change 10,274 $9K
Investors Asset Management of Georgia Inc. /Ga/ 0.00% No change 10,000 $8K
Pinnacle Financial Group, LLC / IL 0.00% No change 10,000 $8K
Federation des caisses Desjardins du Quebec 0.00% No change 3,300 $3K
BlackRock, Inc. 0.00% No change 2,037 $2K
Key Financial Inc 0.00% No change 830 $691
Private Wealth Management Group, LLC 0.00% No change 310 $262
Citigroup Inc. 0.00% New 258 $217
Bank of America Corp. 0.00% Reduce -25.7% 246 $207

"% of holder's portfolio" is XLO's weight in each manager's 13F, not the share of Xilio Therapeutics Inc. the manager owns.