XencorXNCR
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 208 institutions reported holding Xencor Inc. (XNCR) in their 13F filings, up 2 from Q3 2025. 26 opened new positions and 28 sold out. The largest holders were BlackRock, Inc. ($182.6M), Primecap Management Co. ($156.4M) and Vanguard Group Inc. ($109.7M). 6 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).
- Company
- Xencor Inc.
- CUSIP
- 98401F105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 26 | $22.5M |
| Exits | 28 | $26.7M |
All 13F filers, Q3 2025 → Q4 2025: 10,076,385 shares bought and 11,780,058 shares sold, net −1,703,673 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 208 holders
| BlackRock, Inc. | 0.00% | Add +1.0% | 11,927,218 | $182.6M |
| Primecap Management Co. | 0.12% | Reduce -4.3% | 10,218,322 | $156.4M |
| Vanguard Group Inc. | 0.00% | Add +0.9% | 7,165,450 | $109.7M |
| BVF Inc. | 3.68% | Add +160.3% | 7,133,720 | $109.2M |
| RTW Investments, LP | 1.04% | Add +8.9% | 6,777,461 | $103.8M |
| State Street Corp. | 0.00% | Add +22.7% | 4,507,254 | $69.0M |
| EcoR1 Capital, LLC | 2.28% | Reduce -47.1% | 3,251,112 | $49.8M |
| TCG Crossover Management, LLC | 1.24% | No change | 2,452,138 | $37.5M |
| Geode Capital Management, LLC | 0.00% | Add +1.4% | 1,752,918 | $26.8M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -5.4% | 1,601,762 | $24.5M |
| Morgan Stanley | 0.00% | Add +67.5% | 1,508,727 | $23.1M |
| Defilade Capital Management, L.P. | 2.94% | — | 1,414,755 | $21.7M |
| Legal & General Group Plc | 0.00% | Add +2.8% | 1,308,088 | $20.0M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -21.4% | 1,249,288 | $19.1M |
| Baker Bros. Advisors LP | 0.10% | No change | 1,102,106 | $16.9M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -26.0% | 753,258 | $11.5M |
| Johnson & Johnson | 2.06% | No change | 748,062 | $11.5M |
| Jefferies Financial Group Inc. | 0.09% | Add +620.4% | 720,440 | $11.0M |
| Lynx1 Capital Management LP | 2.19% | New | 705,558 | $10.8M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +1.8% | 700,435 | $10.7M |
| Northern Trust Corp. | 0.00% | Reduce -5.3% | 674,657 | $10.3M |
| UBS Group AG | 0.00% | Reduce -45.7% | 638,021 | $9.8M |
| Bank of America Corp. | 0.00% | Reduce -16.5% | 629,408 | $9.6M |
| Millennium Management | 0.01% | Reduce -15.4% | 594,435 | $9.1M |
| Panagora Asset Management Inc. | 0.03% | Reduce -6.0% | 583,778 | $8.9M |
| Two Sigma Advisers, LP | 0.02% | Reduce -37.5% | 506,600 | $7.8M |
| Toronto Dominion Bank | 0.01% | Add +882.0% | 491,000 | $7.5M |
| Erste Asset Management GmbH | 0.06% | Add +26.3% | 480,200 | $7.3M |
| Braidwell LP | 0.27% | Reduce -63.2% | 459,166 | $7.0M |
| Hudson Bay Capital Management LP | 0.04% | Reduce -7.6% | 425,000 | $6.5M |
| Acadian Asset Management LLC | 0.01% | Reduce -22.6% | 411,725 | $6.3M |
| Bank of New York Mellon Corp | 0.00% | Reduce -3.6% | 410,650 | $6.3M |
| Barclays PLC | 0.00% | Reduce -40.2% | 359,235 | $5.5M |
| Principal Financial Group Inc. | 0.00% | Reduce -1.2% | 340,326 | $5.2M |
| Citadel Advisors | 0.00% | Reduce -33.1% | 321,808 | $4.9M |
| JPMorgan Chase & Co. | 0.00% | Reduce -24.3% | 303,979 | $4.7M |
| Two Sigma Investments, LP | 0.01% | Reduce -57.3% | 268,737 | $4.1M |
| Invesco Ltd. | 0.00% | Add +5.7% | 265,820 | $4.1M |
| Jacobs Levy Equity Management, Inc. | 0.02% | New | 259,319 | $4.0M |
| Public Sector Pension Investment Board | 0.01% | Reduce -11.1% | 247,242 | $3.8M |
| Deutsche Bank AG | 0.00% | Add +378.8% | 216,568 | $3.3M |
| Nomura Asset Management International Inc. | 0.00% | — | 200,000 | $3.1M |
| Woodline Partners LP | 0.01% | No change | 193,117 | $3.0M |
| Susquehanna Portfolio Strategies, LLC | 0.05% | Add +79.2% | 191,463 | $2.9M |
| Trexquant Investment LP | 0.02% | Add +28.7% | 175,152 | $2.7M |
| American Century Companies Inc. | 0.00% | Add +0.7% | 174,603 | $2.7M |
| Rhumbline Advisers | 0.00% | Reduce -5.7% | 165,797 | $2.5M |
| Rhenman & Partners Asset Management AB | 0.24% | No change | 165,750 | $2.5M |
| Nantahala Capital Management, LLC | 0.15% | Reduce -85.0% | 164,639 | $2.5M |
| DCF Advisers, LLC | 0.78% | Reduce -18.4% | 154,736 | $2.4M |
| Ameriprise Financial Inc. | 0.00% | Reduce -7.4% | 135,806 | $2.1M |
| Nuveen, LLC | 0.00% | No change | 134,051 | $2.1M |
| SG Americas Securities, LLC | 0.00% | Add +41.8% | 128,345 | $2.0M |
| Algert Global LLC | 0.03% | Reduce -65.5% | 124,400 | $1.9M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -27.9% | 119,789 | $1.8M |
| Swiss National Bank | 0.00% | Add +3.7% | 119,600 | $1.8M |
| Citigroup Inc. | 0.00% | Add +374.5% | 112,275 | $1.7M |
| AQR Capital Management | 0.00% | Add +29.3% | 112,271 | $1.7M |
| Seven Fleet Capital Management LP | 1.14% | — | 109,554 | $1.7M |
| Essex LLC | 0.27% | Reduce -1.2% | 98,661 | $1.5M |
| Rafferty Asset Management, LLC | 0.01% | Add +39.9% | 97,749 | $1.5M |
| FMR LLC | 0.00% | Add +25.6% | 92,883 | $1.4M |
| WINTON GROUP Ltd | 0.05% | Reduce -29.8% | 88,038 | $1.3M |
| Voloridge Investment Management, LLC | 0.00% | New | 87,717 | $1.3M |
| Thrivent Financial for Lutherans | 0.00% | Reduce -5.4% | 82,828 | $1.3M |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -12.8% | 82,942 | $1.3M |
| Wells Fargo & Company | 0.00% | Add +45.5% | 79,667 | $1.2M |
| TD Asset Management Inc | 0.00% | Reduce -9.3% | 77,802 | $1.2M |
| Alliancebernstein L.P. | 0.00% | No change | 72,090 | $1.1M |
| Intech Investment Management LLC | 0.01% | Add +138.6% | 70,612 | $1.1M |
| New York State Teachers Retirement System | 0.00% | Add +18.3% | 70,526 | $1.1M |
| Prudential Financial Inc. | 0.00% | Reduce -6.2% | 67,570 | $1.0M |
| NEOS Investment Management LLC | 0.01% | New | 61,362 | $939K |
| Tema ETFs LLC | 0.07% | New | 60,457 | $926K |
| Alps Advisors Inc. | 0.01% | Add +72.3% | 58,639 | $898K |
| California State Teachers Retirement System | 0.00% | Reduce -0.1% | 58,530 | $896K |
| CANADA LIFE ASSURANCE Co | 0.00% | Reduce -18.4% | 57,164 | $875K |
| ADAR1 Capital Management, LLC | 0.06% | Reduce -56.4% | 56,165 | $860K |
| Point72 Asset Management | 0.00% | New | 55,339 | $847K |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 31,800 | $775K |
| BNP Paribas Financial Markets | 0.00% | Reduce -60.8% | 48,687 | $745K |
| Schonfeld Strategic Advisors LLC | 0.00% | Add +274.9% | 47,848 | $733K |
| Russell Investments Group, Ltd. | 0.00% | Add +293.1% | 47,189 | $722K |
| Quantinno Capital Management LP | 0.00% | Add +4.5% | 47,134 | $722K |
| Profund Advisors LLC | 0.02% | Add +150.0% | 43,960 | $673K |
| Franklin Resources Inc. | 0.00% | Reduce -7.7% | 41,225 | $631K |
| Linden Thomas Advisory Services, LLC | 0.06% | Reduce -4.2% | 40,963 | $627K |
| MetLife Investment Management, LLC | 0.00% | Add +14.6% | 40,212 | $616K |
| CIBC Private Wealth Group LLC | 0.00% | Reduce -23.9% | 40,017 | $613K |
| State of Wisconsin Investment Board | 0.00% | Add +109.3% | 38,825 | $594K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +4.9% | 38,448 | $587K |
| Raymond James Financial Inc. | 0.00% | Add +127.4% | 38,037 | $582K |
| State of Alaska, Department of Revenue | 0.01% | Add +1.4% | 36,407 | $557K |
| Tudor Investment Corporation | 0.00% | New | 34,794 | $533K |
| Renaissance Technologies | 0.00% | Reduce -82.1% | 34,158 | $523K |
| Jump Financial, LLC | 0.01% | Reduce -81.1% | 33,198 | $508K |
| Louisiana State Employees Retirement System | 0.01% | Reduce -0.3% | 32,700 | $501K |
| XTX Topco Ltd | 0.01% | New | 32,009 | $490K |
| Los Angeles Capital Management LLC | 0.00% | Reduce -65.5% | 34,097 | $482K |
| Cerity Partners LLC | 0.00% | Add +3.8% | 31,302 | $479K |
"% of holder's portfolio" is XNCR's weight in each manager's 13F, not the share of Xencor Inc. the manager owns.