Zentalis PharmaceuticalsZNTL

13F holders, Q2 2025 (June 30)
117holders −15
21new positions
37sold out
6famous investors
$1.16avg. 13F price*

At the end of Q2 2025, 117 institutions reported holding Zentalis Pharmaceuticals Inc. (ZNTL) in their 13F filings, down 15 from Q1 2025. 21 opened new positions and 37 sold out. The largest holders were Matrix Capital Management Company, LP ($16.2M), Millennium Management ($4.0M) and Vanguard Group Inc. ($3.3M). 6 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio).

Company
Zentalis Pharmaceuticals Inc.
CUSIP
98943L107
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150 Q1 2024: 142Q1 2024Q2 2024: 145Q2 2024Q3 2024: 136Q3 2024Q4 2024: 142Q4 2024Q1 2025: 132Q1 2025Q2 2025: 117Q2 2025Q3 2025: 99Q3 2025Q4 2025: 86Q4 2025Q1 2026: 102Q1 2026Q2 2026: 114Q2 2026

Total Exit/New Position Q1 2025 → Q2 2025

InstitutionsTotal Value
New Positions21$1.8M
Exits37$3.0M

All 13F filers, Q1 2025 → Q2 2025: 7,957,899 shares bought and 10,803,697 shares sold, net −2,845,798 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 117 holders

Matrix Capital Management Company, LP 7.27% No change 13,959,973 $16.2M
Millennium Management 0.00% Add +13.3% 3,476,808 $4.0M
Vanguard Group Inc. 0.00% Reduce -11.5% 2,884,632 $3.3M
Acadian Asset Management LLC 0.01% Add +4.7% 2,799,020 $3.2M
Opaleye Management Inc. 0.46% Reduce -3.1% 1,924,300 $2.2M
BlackRock, Inc. 0.00% Reduce -58.8% 1,741,747 $2.0M
Almitas Capital LLC 0.47% Reduce -6.5% 1,599,266 $1.9M
Tang Capital Management LLC 0.09% Add +3.3% 1,550,000 $1.8M
Renaissance Technologies 0.00% Add +85.2% 1,529,553 $1.8M
Tybourne Capital Management (hk) Ltd. 4.96% Add +53.7% 1,478,152 $1.7M
Decheng Capital LLC 0.39% Reduce -34.5% 1,323,327 $1.5M
Two Sigma Advisers, LP 0.00% Add +51.4% 1,275,914 $1.5M
D. E. Shaw & Co. 0.00% Add +7.1% 1,197,624 $1.4M
Gsa Capital Partners LLP 0.09% Add +109.1% 1,133,375 $1.3M
Morgan Stanley 0.00% Add +0.3% 1,097,651 $1.3M
Two Sigma Investments, LP 0.00% Add +99.0% 1,093,053 $1.3M
Primecap Management Co. 0.00% Reduce -18.7% 1,027,620 $1.2M
Balyasny Asset Management L.P. 0.00% New 970,862 $1.1M
Pfizer Inc 0.19% No change 953,834 $1.1M
Goldman Sachs Group Inc. 0.00% Add +88.8% 861,767 $1000K
Jacobs Levy Equity Management, Inc. 0.00% Add +145.8% 857,582 $995K
Bank of America Corp. 0.00% Reduce -36.9% 713,315 $827K
Jane Street Group, LLC 0.00% Add +346.3% 664,061 $770K
Geode Capital Management, LLC 0.00% Reduce -54.4% 618,167 $717K
Peapod Lane Capital LLC 0.65% Add +0.1% 559,213 $649K
JPMorgan Chase & Co. 0.00% Reduce -26.3% 550,447 $639K
Woodline Partners LP 0.00% No change 530,582 $615K
5AM Venture Management, LLC 0.22% No change 490,000 $568K
Citadel Advisors 0.00% Add +550.6% 462,340 $536K
AQR Capital Management 0.00% Reduce -29.8% 434,958 $505K
Man Group plc 0.00% Add +302.3% 406,344 $471K
Dimensional Fund Advisors LP 0.00% Reduce -24.9% 335,966 $390K
Cubist Systematic Strategies, LLC 0.00% Add +309.6% 320,318 $372K
Connor, Clark & Lunn Investment Management Ltd. 0.00% Reduce -12.8% 314,845 $365K
Charles Schwab Investment Management Inc. 0.00% Reduce -38.5% 299,097 $347K
State Street Corp. 0.00% Reduce -79.4% 271,790 $315K
XTX Topco Ltd 0.01% Add +112.9% 264,829 $307K
Wealth Enhancement Advisory Services, LLC 0.00% Reduce -25.7% 174,006 $219K
FMR LLC 0.00% Add +1.4% 184,677 $214K
BNP Paribas Financial Markets 0.00% Add +144.9% 173,484 $201K
Sei Investments Co. 0.00% Reduce -17.4% 167,100 $194K
Invesco Ltd. 0.00% Add +4.2% 155,714 $181K
Russell Investments Group, Ltd. 0.00% Reduce -0.8% 150,990 $175K
Susquehanna International Group, LLP 0.00% Add +37.9% 145,769 $169K
Walleye Capital LLC 0.00% Reduce -62.0% 129,867 $151K
UBS Group AG 0.00% Reduce -8.8% 129,468 $150K
Northern Trust Corp. 0.00% Reduce -73.3% 123,444 $143K
HRT Financial LP 0.00% New 113,863 $132K
Stonepine Capital Management, LLC 0.12% Add +81.7% 109,010 $126K
Quarry LP 0.03% Reduce -12.5% 105,000 $122K
Ameriprise Financial Inc. 0.00% Add +622.8% 91,195 $106K
Ieq Capital, LLC 0.00% Reduce -8.1% 86,300 $100K
RBF Capital, LLC 0.00% New 80,000 $93K
Bridgeway Capital Management, LLC 0.00% Reduce -49.2% 77,300 $90K
State of Wyoming 0.01% Add +63.4% 73,797 $86K
Jain Global LLC 0.00% New 72,261 $84K
Anfield Capital Management, LLC 0.03% No change 71,377 $83K
Thrivent Financial for Lutherans 0.00% No change 70,641 $82K
Commonwealth Equity Services, LLC 0.00% Add +0.5% 60,987 $71K
Point72 Asia (Singapore) Pte. Ltd. 0.01% Add +228.4% 59,453 $69K
Quadrature Capital Ltd 0.00% New 52,456 $61K
Universal- Beteiligungs- und Servicegesellschaft mbH 0.00% No change 51,061 $59K
ADAR1 Capital Management, LLC 0.01% New 50,000 $58K
Squarepoint Ops LLC 0.00% Reduce -5.4% 46,461 $54K
T. Rowe Price Associates Inc. 0.00% Reduce -40.5% 41,454 $49K
Barr E S & Co. 0.00% No change 40,000 $46K
Federated Hermes, Inc. 0.00% Reduce -94.7% 39,736 $46K
Public Employees Retirement System of Ohio 0.00% Add +351.8% 36,700 $43K
Corient Private Wealth LP 0.00% New 35,760 $41K
Graham Capital Management, L.P. 0.00% Reduce -71.6% 35,475 $41K
Tudor Investment Corporation 0.00% No change 34,849 $40K
Y-Intercept (Hong Kong) Ltd 0.00% New 32,740 $38K
Qube Research & Technologies Ltd 0.00% New 32,113 $37K
Creative Planning 0.00% Reduce -87.2% 30,340 $35K
Carson Advisory Inc. 0.02% No change 29,570 $34K
Regency Capital Management Inc.\DE 0.02% No change 29,500 $34K
HSBC Holdings PLC 0.00% New 27,877 $33K
Cwm, LLC 0.00% Reduce -27.8% 28,646 $33K
Catalyst Funds Management Pty Ltd 0.01% New 26,800 $31K
Harvest Investment Services, LLC 0.01% Add +2.9% 25,472 $30K
SG Americas Securities, LLC 0.00% Reduce -3.2% 23,343 $27K
49 Wealth Management, LLC 0.00% Reduce -52.7% 21,546 $25K
Raymond James Financial Inc. 0.00% Reduce -7.5% 20,595 $24K
Acorn Wealth Advisors, LLC 0.01% New 20,000 $23K
Citigroup Inc. 0.00% Reduce -52.2% 19,447 $23K
Prudential Financial Inc. 0.00% Reduce -40.9% 18,900 $22K
Tower Research Capital LLC (TRC) 0.00% Add +226.5% 17,114 $20K
Birchview Capital, LP 0.02% No change 17,000 $20K
Evergreen Capital Management LLC 0.00% No change 16,915 $20K
DRW Securities, LLC 0.00% New 16,830 $20K
Hudson Bay Capital Management LP 0.00% New 16,638 $19K
Engineers Gate Manager LP 0.00% New 13,021 $15K
Captrust Financial Advisors 0.00% Reduce -25.7% 11,842 $14K
Jump Financial, LLC 0.00% New 11,692 $14K
R Squared Ltd 0.01% New 10,808 $13K
Dynamic Technology Lab Private Ltd 0.00% Reduce -46.6% 10,546 $12K
Simplex Trading, LLC 0.00% Add +527.8% 9,699 $11K
Highline Wealth Partners LLC 0.00% New 7,000 $8K
Caitong International Asset Management Co., Ltd 0.00% Add +30044.4% 2,713 $3K
EverSource Wealth Advisors, LLC 0.00% Reduce -5.1% 2,350 $3K
Wells Fargo & Company 0.00% Reduce -93.6% 2,278 $3K
Group One Trading LLC 0.00% Reduce -90.9% 2,271 $3K
Clearstead Advisors, LLC 0.00% New 2,061 $2K
Royal Bank of Canada 0.00% Reduce -61.3% 2,441 $2K
US Bancorp \de 0.00% Reduce -87.5% 1,164 $1K
Wilmington Savings Fund Society, FSB 0.00% No change 1,000 $1K
Nisa Investment Advisors, LLC 0.00% Add +18.4% 387 $449
HighMark Wealth Management LLC 0.00% No change 130 $151
Essential Partners LLC 0.00% — 58 $67
Allworth Financial LP 0.00% New 42 $49
IFP Advisors, Inc 0.00% New 35 $40
PNC Financial Services Group, Inc. 0.00% Reduce -95.5% 28 $32
SBI Securities Co., Ltd. 0.00% No change 27 $31
Osaic Holdings, Inc. 0.00% No change 10 $12
True Wealth Design, LLC 0.00% Reduce -88.8% 9 $11
Barclays PLC 0.00% Reduce -100.0% 1 $1
Covestor Ltd 0.00% Add +126.1% 52 $0

"% of holder's portfolio" is ZNTL's weight in each manager's 13F, not the share of Zentalis Pharmaceuticals Inc. the manager owns.