Act Capital Management, LLC

In its 13F for Q4 2025 (holdings as of December 31, 2025, filed February 17, 2026), Act Capital Management, LLC reported 58 stock positions worth $123.7 million. Its top holding was Krystal Biotech (KRYS) at 12.1% of the portfolio, followed by Chevron (CVX, 9.7%) and Exxon Mobil (XOM, 8.0%).

Most Recent 13F
Q2 2026
Location
WAYNE, PA
CIK
0001442273
Portfolio Value
$123.7M (Q4 2025)
SEC Filing
0001636587-26-000006 ↗ filed Feb 17, 2026

Holdings Value

0$50.0M$100.0M$150.0M$200.0M Q4 2025: $123.7M $123.7M Q4 2025 Q1 2026: $127.2M Q1 2026 Q2 2026: $153.1M Q2 2026

Holdings 58 stocks · $123.7M

KRYS Krystal Biotech Inc. 12.06% 60,500 $14.9M —
CVX Chevron Corp. 9.67% 78,500 $12.0M —
XOM Exxon Mobil Corp. 8.03% 82,500 $9.9M —
ABVX Abivax SA-ADR 6.97% 63,900 $8.6M —
TGTX TG Therapeutics Inc. 6.48% 268,875 $8.0M —
VKTX Viking Therapeutics Inc. 5.86% 206,100 $7.3M —
CELC Celcuity Inc. 5.11% 63,415 $6.3M —
AMZN Amazon.com Inc. 4.59% 24,600 $5.7M —
NUVB Nuvation Bio Inc. 4.42% 610,500 $5.5M —
ARWR Arrowhead Pharmaceuticals Inc. 4.03% 75,000 $5.0M —
CYTK Cytokinetics Inc. 3.31% 64,500 $4.1M —
CELCUITY INC COM MAR 20 26 $50 CALL (CELC) 2.46% 30,500 $3.0M —
GPCR Structure Therapeutics Inc. 2.17% 38,500 $2.7M —
GBTC Grayscale Bitcoin Trust ETF 1.90% 34,400 $2.4M —
FIGR Figure Technology Solut Class A 1.90% 57,500 $2.3M —
SPOT Spotify Technology SA 1.88% 4,000 $2.3M —
ET Energy Transfer LP 1.77% 133,100 $2.2M —
NKTR Nektar Therapeutics 1.75% 51,200 $2.2M —
OLMA Olema Pharmaceuticals Inc. 1.08% 53,500 $1.3M —
IBM Intl Business Machines Corp. filed as INTERNATIONAL BUSINESS MACHS 1.08% 4,500 $1.3M —
STAA Staar Surgical Co. 1.04% 55,500 $1.3M —
CELCUITY INC COM MAR 20 26 $35 CALL (CELC) 1.01% 12,500 $1.2M —
RGNX Regenxbio Inc. 0.96% 82,500 $1.2M —
BE Bloom Energy Corp. Class A 0.91% 13,000 $1.1M —
HCC Warrior Met Coal Inc. 0.86% 12,000 $1.1M —
EOG EOG Resources Inc. 0.85% 10,000 $1.1M —
SNDK Sandisk Corp. 0.67% 3,500 $831K —
DVN Devon Energy Corp. 0.65% 22,000 $806K —
PATH Uipath Inc. Class A 0.62% 47,000 $770K —
KURA Kura Oncology Inc. 0.62% 73,900 $768K —
TEVA Teva Pharmaceutical-SP ADR 0.58% 23,000 $718K —
REPL Replimune Group Inc. 0.48% 61,500 $598K —
SRRK Scholar Rock Holding Corp. 0.43% 12,000 $529K —
APGE Apogee Therapeutics Inc. 0.43% 7,000 $528K —
CRGY Crescent Energy Inc. Class A 0.42% 61,312 $514K —
WGS Genedx Holdings Corp. 0.32% 3,000 $390K —
PALI Palisade Bio Inc. 0.28% 150,000 $353K —
ACOG Alpha Cognition Inc. 0.27% 51,500 $335K —
LQDA Liquidia Corp. 0.24% 8,500 $293K —
KYTX Kyverna Therapeutics Inc. 0.19% 25,100 $236K —
BW Babcock & Wilcox Enterpr 0.19% 36,500 $231K —
ALDX Aldeyra Therapeutics Inc. 0.17% 41,000 $212K —
NKLR Terra Innovatum Global NV 0.17% 45,000 $208K —
PRAX Praxis Precision Medicines I 0.17% 700 $206K —
ESPR Esperion Therapeutics Inc. 0.14% 47,500 $176K —
LSPD Lightspeed Commerce Inc. 0.12% 12,500 $151K —
DAWN Day One Biopharmaceuticals I 0.10% 12,900 $120K —
TVTX Travere Therapeutics Inc. 0.09% 3,000 $115K —
AMLX Amylyx Pharmaceuticals Inc. 0.09% 9,000 $109K —
WY Weyerhaeuser Co. 0.09% 4,500 $107K —
SSYS Stratasys Ltd. 0.07% 10,000 $87K —
BHVN Biohaven Ltd. 0.07% 7,500 $85K —
BTC Grayscale Bitcoin Mini ETF 0.06% 1,800 $70K —
CAPR Capricor Therapeutics Inc. 0.04% 1,500 $43K —
NVNO Envveno Medical Corporation 0.03% 115,000 $37K —
YALA Yalla Group Ltd. 0.03% 5,000 $35K —
PDSB PDS Biotechnology Corp. 0.02% 30,000 $23K —
MLTX Moonlake Immunotherapeutics 0.02% 1,500 $20K —

Portfolio Sells Q4 2025

No earlier filing to compare with.

Portfolio Buys Q4 2025

No earlier filing to compare with.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 62$153.1MKRYS, TGTX, ABVX, CVX, XOM
Q1 2026 56$127.2MKRYS, CVX, XOM, CELC, TGTX
Q4 2025 58$123.7MKRYS, CVX, XOM, ABVX, TGTX