Act Capital Management, LLC
In its 13F for Q1 2026 (holdings as of March 31, 2026, filed May 8, 2026), Act Capital Management, LLC reported 56 stock positions worth $127.2 million. Its top holding was Krystal Biotech (KRYS) at 12.3% of the portfolio, followed by Chevron (CVX, 12.2%) and Exxon Mobil (XOM, 9.3%). Compared with Q4 2025, it opened 20 new positions, sold out of 22, added to 12 and reduced 12. The biggest buy was Celcuity (CELC, shares +45%) and the biggest sale Nuvation Bio (NUVB, shares −53%).
- Most Recent 13F
- Q2 2026
- Location
- WAYNE, PA
- CIK
- 0001442273
- Portfolio Value
- $127.2M (Q1 2026)
- SEC Filing
- 0001636587-26-000028 ↗ filed May 8, 2026
Holdings Value
Holdings 56 stocks · $127.2M
| KRYS Krystal Biotech Inc. | 12.28% | 60,477 | $15.6M | Reduce -0.0% |
| CVX Chevron Corp. | 12.20% | 75,000 | $15.5M | Reduce -4.5% |
| XOM Exxon Mobil Corp. | 9.33% | 70,000 | $11.9M | Reduce -15.2% |
| CELC Celcuity Inc. | 8.22% | 91,675 | $10.5M | Add +44.6% |
| TGTX TG Therapeutics Inc. | 6.50% | 249,025 | $8.3M | Reduce -7.4% |
| ABVX Abivax SA-ADR | 6.20% | 70,900 | $7.9M | Add +10.9% |
| AMZN Amazon.com Inc. | 5.40% | 33,000 | $6.9M | Add +34.1% |
| VKTX Viking Therapeutics Inc. | 5.35% | 209,300 | $6.8M | Add +1.6% |
| ARWR Arrowhead Pharmaceuticals Inc. | 4.07% | 82,500 | $5.2M | Add +10.0% |
| NKTR Nektar Therapeutics | 4.01% | 70,900 | $5.1M | Add +38.5% |
| CYTK Cytokinetics Inc. | 3.34% | 64,500 | $4.3M | No change |
| ALMS Alumis Inc. | 3.02% | 174,250 | $3.8M | New |
| ET Energy Transfer LP | 2.02% | 133,100 | $2.6M | No change |
| FCX Freeport-McMoran Inc. | 1.78% | 38,500 | $2.3M | New |
| AAOI Applied Optoelectronics Inc. | 1.72% | 25,900 | $2.2M | New |
| XENE Xenon Pharmaceuticals Inc. | 1.53% | 33,500 | $1.9M | New |
| NUVB Nuvation Bio Inc. | 0.98% | 290,000 | $1.2M | Reduce -52.5% |
| STAA Staar Surgical Co. | 0.82% | 55,500 | $1.0M | No change |
| PRAX Praxis Precision Medicines I | 0.68% | 2,700 | $870K | Add +285.7% |
| GBTC Grayscale Bitcoin Trust ETF | 0.64% | 15,400 | $813K | Reduce -55.2% |
| S Sentinelone Inc. Class A | 0.55% | 54,300 | $699K | New |
| LITE Lumentum Holdings Inc. | 0.50% | 900 | $632K | New |
| BE Bloom Energy Corp. Class A | 0.48% | 4,500 | $610K | Reduce -65.4% |
| CRGY Crescent Energy Inc. Class A | 0.48% | 45,000 | $608K | Reduce -26.6% |
| KURA Kura Oncology Inc. | 0.47% | 73,900 | $601K | No change |
| VIR Vir Biotechnology Inc. | 0.45% | 64,300 | $576K | New |
| CRCL Circle Internet Group Inc. | 0.45% | 6,000 | $572K | New |
| HCC Warrior Met Coal Inc. | 0.44% | 6,000 | $559K | Reduce -50.0% |
| PATH Uipath Inc. Class A | 0.44% | 50,000 | $555K | Add +6.4% |
| SRRK Scholar Rock Holding Corp. | 0.42% | 10,800 | $531K | Reduce -10.0% |
| WGS Genedx Holdings Corp. | 0.40% | 8,000 | $514K | Add +166.7% |
| MU Micron Technology Inc. | 0.40% | 1,500 | $507K | New |
| NVDA Nvidia Corp. | 0.38% | 2,800 | $488K | New |
| REPL Replimune Group Inc. | 0.37% | 61,500 | $470K | No change |
| RGNX Regenxbio Inc. | 0.37% | 56,000 | $469K | Reduce -32.1% |
| PALI Palisade Bio Inc. | 0.35% | 257,500 | $451K | Add +71.7% |
| OLMA Olema Pharmaceuticals Inc. | 0.29% | 25,000 | $373K | Reduce -53.3% |
| GLUE Monte Rosa Therapeutics Inc. | 0.29% | 22,500 | $370K | New |
| ONDS Ondas Inc. | 0.27% | 37,500 | $339K | New |
| ACOG Alpha Cognition Inc. | 0.22% | 51,500 | $283K | No change |
| MBX MBX Biosciences Inc. | 0.21% | 9,000 | $269K | New |
| APC Arko Petroleum Corp. | 0.21% | 15,000 | $268K | New |
| KYTX Kyverna Therapeutics Inc. | 0.20% | 30,000 | $259K | Add +19.5% |
| RYZ Ryerson Holding Corp. | 0.19% | 10,800 | $243K | New |
| NKLR Terra Innovatum Global NV | 0.16% | 45,000 | $209K | No change |
| INCY Incyte Corp. | 0.15% | 2,000 | $188K | New |
| CAPR Capricor Therapeutics Inc. | 0.12% | 5,000 | $152K | Add +233.3% |
| VPG Vishay Precision Group | 0.10% | 3,000 | $130K | New |
| ESPR Esperion Therapeutics Inc. | 0.10% | 47,500 | $130K | No change |
| AMLX Amylyx Pharmaceuticals Inc. | 0.10% | 9,000 | $125K | No change |
| LSPD Lightspeed Commerce Inc. | 0.09% | 12,500 | $112K | No change |
| CMPS Compass Pathways PLC | 0.07% | 15,500 | $86K | New |
| LTRX Lantronix Inc. | 0.06% | 15,000 | $79K | New |
| SSYS Stratasys Ltd. | 0.06% | 10,000 | $78K | No change |
| HIMS Hims & Hers Health Inc. | 0.04% | 2,500 | $52K | New |
| PDSB PDS Biotechnology Corp. | 0.01% | 30,000 | $18K | No change |
Portfolio Sells Q4 2025 → Q1 2026
| NUVB Nuvation Bio Inc. | Reduce -52.5% | 0.98% | −3.45 |
| CELCUITY INC COM MAR 20 26 $50 CALL (CELC) | Sold out | 0.00% | −2.46 |
| GPCR Structure Therapeutics Inc. | Sold out | 0.00% | −2.17 |
| FIGR Figure Technology Solut Class A | Sold out | 0.00% | −1.90 |
| SPOT Spotify Technology SA | Sold out | 0.00% | −1.88 |
| GBTC Grayscale Bitcoin Trust ETF | Reduce -55.2% | 0.64% | −1.26 |
| IBM Intl Business Machines Corp. | Sold out | 0.00% | −1.08 |
| CELCUITY INC COM MAR 20 26 $35 CALL (CELC) | Sold out | 0.00% | −1.01 |
| EOG EOG Resources Inc. | Sold out | 0.00% | −0.85 |
| OLMA Olema Pharmaceuticals Inc. | Reduce -53.3% | 0.29% | −0.79 |
| SNDK Sandisk Corp. | Sold out | 0.00% | −0.67 |
| DVN Devon Energy Corp. | Sold out | 0.00% | −0.65 |
| RGNX Regenxbio Inc. | Reduce -32.1% | 0.37% | −0.59 |
| TEVA Teva Pharmaceutical-SP ADR | Sold out | 0.00% | −0.58 |
| BE Bloom Energy Corp. Class A | Reduce -65.4% | 0.48% | −0.43 |
| APGE Apogee Therapeutics Inc. | Sold out | 0.00% | −0.43 |
| HCC Warrior Met Coal Inc. | Reduce -50.0% | 0.44% | −0.42 |
| LQDA Liquidia Corp. | Sold out | 0.00% | −0.24 |
| BW Babcock & Wilcox Enterpr | Sold out | 0.00% | −0.19 |
| ALDX Aldeyra Therapeutics Inc. | Sold out | 0.00% | −0.17 |
| DAWN Day One Biopharmaceuticals I | Sold out | 0.00% | −0.10 |
| TVTX Travere Therapeutics Inc. | Sold out | 0.00% | −0.09 |
| WY Weyerhaeuser Co. | Sold out | 0.00% | −0.09 |
| BHVN Biohaven Ltd. | Sold out | 0.00% | −0.07 |
| BTC Grayscale Bitcoin Mini ETF | Sold out | 0.00% | −0.06 |
| NVNO Envveno Medical Corporation | Sold out | 0.00% | −0.03 |
| YALA Yalla Group Ltd. | Sold out | 0.00% | −0.03 |
| MLTX Moonlake Immunotherapeutics | Sold out | 0.00% | −0.02 |
| SRRK Scholar Rock Holding Corp. | Reduce -10.0% | 0.42% | −0.01 |
| TGTX TG Therapeutics Inc. | Reduce -7.4% | 6.50% | +0.02 |
| CRGY Crescent Energy Inc. Class A | Reduce -26.6% | 0.48% | +0.06 |
| KRYS Krystal Biotech Inc. | Reduce -0.0% | 12.28% | +0.22 |
| XOM Exxon Mobil Corp. | Reduce -15.2% | 9.33% | +1.31 |
| CVX Chevron Corp. | Reduce -4.5% | 12.20% | +2.52 |
Portfolio Buys Q4 2025 → Q1 2026
| CELC Celcuity Inc. | Add +44.6% | 8.22% | +3.11 |
| ALMS Alumis Inc. | New | 3.02% | +3.02 |
| NKTR Nektar Therapeutics | Add +38.5% | 4.01% | +2.26 |
| FCX Freeport-McMoran Inc. | New | 1.78% | +1.78 |
| AAOI Applied Optoelectronics Inc. | New | 1.72% | +1.72 |
| XENE Xenon Pharmaceuticals Inc. | New | 1.53% | +1.53 |
| AMZN Amazon.com Inc. | Add +34.1% | 5.40% | +0.81 |
| S Sentinelone Inc. Class A | New | 0.55% | +0.55 |
| PRAX Praxis Precision Medicines I | Add +285.7% | 0.68% | +0.52 |
| LITE Lumentum Holdings Inc. | New | 0.50% | +0.50 |
| VIR Vir Biotechnology Inc. | New | 0.45% | +0.45 |
| CRCL Circle Internet Group Inc. | New | 0.45% | +0.45 |
| MU Micron Technology Inc. | New | 0.40% | +0.40 |
| NVDA Nvidia Corp. | New | 0.38% | +0.38 |
| GLUE Monte Rosa Therapeutics Inc. | New | 0.29% | +0.29 |
| ONDS Ondas Inc. | New | 0.27% | +0.27 |
| MBX MBX Biosciences Inc. | New | 0.21% | +0.21 |
| APC Arko Petroleum Corp. | New | 0.21% | +0.21 |
| RYZ Ryerson Holding Corp. | New | 0.19% | +0.19 |
| INCY Incyte Corp. | New | 0.15% | +0.15 |
| VPG Vishay Precision Group | New | 0.10% | +0.10 |
| WGS Genedx Holdings Corp. | Add +166.7% | 0.40% | +0.09 |
| CAPR Capricor Therapeutics Inc. | Add +233.3% | 0.12% | +0.08 |
| PALI Palisade Bio Inc. | Add +71.7% | 0.35% | +0.07 |
| CMPS Compass Pathways PLC | New | 0.07% | +0.07 |
| LTRX Lantronix Inc. | New | 0.06% | +0.06 |
| HIMS Hims & Hers Health Inc. | New | 0.04% | +0.04 |
| ARWR Arrowhead Pharmaceuticals Inc. | Add +10.0% | 4.07% | +0.04 |
| KYTX Kyverna Therapeutics Inc. | Add +19.5% | 0.20% | +0.01 |
| PATH Uipath Inc. Class A | Add +6.4% | 0.44% | −0.19 |
| VKTX Viking Therapeutics Inc. | Add +1.6% | 5.35% | −0.51 |
| ABVX Abivax SA-ADR | Add +10.9% | 6.20% | −0.76 |