Eventide Asset Management, LLC
In its 13F for Q3 2025 (holdings as of September 30, 2025, filed November 14, 2025), Eventide Asset Management, LLC reported 239 stock positions worth $6.1 billion. Its top holding was Guardant Health (GH) at 3.4% of the portfolio, followed by Mirum Pharmaceuticals (MIRM, 3.0%) and Xometry Class A (XMTR, 2.8%). Compared with Q2 2025, it opened 25 new positions, sold out of 23, added to 137 and reduced 69. The biggest buy was Talen Energy (TLN, shares +282%) and the biggest sale Verona Pharma (VRNA, shares −75%).
- Most Recent 13F
- Q2 2026
- Location
- Boston, MA
- CIK
- 0001442891
- Portfolio Value
- $6.1B (Q3 2025)
- SEC Filing
- 0001580642-25-007287 ↗ filed Nov 14, 2025
Holdings Value
Holdings 239 stocks · $6.1B
| GH Guardant Health Inc. | 3.41% | 3,321,338 | $207.5M | Reduce -4.0% |
| MIRM Mirum Pharmaceuticals Inc. | 3.04% | 2,522,563 | $184.9M | Reduce -4.4% |
| XMTR Xometry Inc. Class A | 2.79% | 3,117,906 | $169.9M | Reduce -1.3% |
| TT Trane Technologies PLC | 2.76% | 398,521 | $168.0M | Add +2.6% |
| INSM Insmed Inc. | 2.38% | 1,005,107 | $144.7M | Reduce -16.0% |
| LRCX Lam Research Corp. | 1.99% | 904,695 | $120.9M | Reduce -9.3% |
| IRTC Irhythm Holdings Inc. | 1.96% | 691,512 | $118.9M | Reduce -0.0% |
| GEV GE Vernova Inc. | 1.95% | 192,698 | $118.4M | Reduce -3.9% |
| SRRK Scholar Rock Holding Corp. | 1.71% | 2,799,456 | $104.3M | Reduce -3.9% |
| BBNX Beta Bionics Inc. | 1.62% | 4,957,252 | $98.5M | Add +0.5% |
| ARGX Argenx SE - ADR | 1.52% | 125,371 | $92.5M | Reduce -0.0% |
| ROP Roper Technologies Inc. | 1.49% | 181,906 | $90.7M | Reduce -0.0% |
| VST Vistra Corp. | 1.49% | 462,841 | $90.7M | Reduce -4.8% |
| AXSM Axsome Therapeutics Inc. | 1.49% | 746,398 | $90.6M | Add +2.9% |
| TOST Toast Inc. Class A | 1.49% | 2,481,575 | $90.6M | Add +0.3% |
| ODFL Old Dominion Freight Line | 1.40% | 606,679 | $85.4M | Add +1.3% |
| COLL Collegium Pharmaceutical Inc. | 1.38% | 2,390,912 | $83.7M | Reduce -9.5% |
| DHI D.R. Horton Inc. | 1.27% | 455,674 | $77.2M | Add +3.1% |
| URI United Rentals Inc. | 1.26% | 80,244 | $76.6M | Add +0.5% |
| VRNA Verona Pharma Ltd. | 1.19% | 680,929 | $72.7M | Reduce -74.9% |
| WMB Williams Cos Inc. | 1.13% | 1,085,237 | $68.9M | Add +3.9% |
| AJG Arthur J Gallagher & Co. filed as GALLAGHER ARTHUR J & CO | 1.10% | 216,693 | $67.1M | Add +2.9% |
| ASML ASML Holding NV-NY Reg SHS | 1.05% | 66,084 | $64.0M | Reduce -2.0% |
| TRGP Targa Resources Corp. | 1.04% | 375,619 | $63.0M | Add +6.9% |
| TMDX Transmedics Group Inc. | 1.01% | 547,296 | $61.4M | Reduce -0.0% |
| ETR Entergy Corp. | 1.00% | 651,043 | $60.7M | Add +9.8% |
| MTD Mettler-Toledo International | 1.00% | 49,443 | $60.6M | Add +1.8% |
| NDAQ Nasdaq Inc. | 0.98% | 674,642 | $59.7M | Add +23.8% |
| ORLY O'reilly Automotive Inc. | 0.94% | 533,086 | $57.5M | Add +0.9% |
| LAD Lithia Motors Inc. | 0.94% | 181,175 | $57.3M | Reduce -2.2% |
| RBA RB Global Inc. | 0.94% | 526,319 | $57.0M | Add +0.4% |
| CHWY Chewy Inc. Class A | 0.94% | 1,409,144 | $57.0M | Add +32.2% |
| WCN Waste Connections Inc. | 0.89% | 309,521 | $54.4M | Add +0.1% |
| CELC Celcuity Inc. | 0.88% | 1,088,799 | $53.8M | Reduce -21.6% |
| NVT Nvent Electric PLC | 0.88% | 541,333 | $53.3M | Add +1.9% |
| EVH Evolent Health Inc. Class A | 0.88% | 6,292,511 | $53.2M | Add +54.0% |
| VMC Vulcan Materials Co. | 0.85% | 167,954 | $51.7M | Reduce -0.0% |
| KLAC KLA Corp. | 0.82% | 46,549 | $50.1M | Add +17.5% |
| DDOG Datadog Inc. Class A | 0.82% | 350,794 | $50.0M | Add +0.5% |
| AXON Axon Enterprise Inc. | 0.82% | 69,104 | $49.6M | Add +2.6% |
| CLDX Celldex Therapeutics Inc. | 0.79% | 1,859,095 | $48.1M | Add +37.1% |
| TLN Talen Energy Corp. | 0.78% | 111,759 | $47.5M | Add +282.3% |
| SITM Sitime Corp. | 0.77% | 155,608 | $46.9M | Add +0.8% |
| ALNY Alnylam Pharmaceuticals Inc. | 0.76% | 101,739 | $46.4M | Reduce -19.2% |
| VRSK Verisk Analytics Inc. | 0.75% | 182,010 | $45.8M | Add +6.4% |
| NTNX Nutanix Inc. Class A | 0.75% | 610,963 | $45.5M | Reduce -3.4% |
| HLI Houlihan Lokey Inc. | 0.74% | 220,048 | $45.2M | Add +12.8% |
| LSCC Lattice Semiconductor Corp. | 0.74% | 610,088 | $44.7M | Add +3.1% |
| NVDA Nvidia Corp. | 0.73% | 238,539 | $44.2M | Reduce -3.7% |
| PNR Pentair PLC | 0.72% | 396,769 | $43.9M | Add +3.2% |
| GLBE Global-E Online Ltd. | 0.71% | 1,215,529 | $43.5M | Reduce -0.7% |
| STE Steris PLC | 0.71% | 175,067 | $43.3M | Add +3.8% |
| ROL Rollins Inc. | 0.69% | 719,047 | $42.2M | Add +15.1% |
| HBAN Huntington Bancshares Inc. | 0.69% | 2,418,727 | $41.8M | Add +30.6% |
| EGP Eastgroup Properties Inc. | 0.68% | 244,320 | $41.4M | Add +3.6% |
| LOW Lowe's Cos Inc. | 0.67% | 162,454 | $40.9M | Add +12.8% |
| HUBS HubSpot Inc. | 0.66% | 86,273 | $40.4M | Add +1.3% |
| FERG Ferguson Enterprises Inc. | 0.66% | 178,772 | $40.2M | Add +18.9% |
| PLD Prologis Inc. | 0.66% | 350,070 | $40.1M | Add +72.9% |
| MSI Motorola Solutions Inc. | 0.64% | 85,161 | $38.9M | Add +4.3% |
| SHW The Sherwin-Williams Co. | 0.63% | 111,408 | $38.5M | Add +3.7% |
| SO The Southern Co. | 0.63% | 406,399 | $38.4M | Add +3.6% |
| MPWR Monolithic Power Systems Inc. | 0.62% | 41,242 | $38.0M | Reduce -2.5% |
| FAST Fastenal Co. | 0.62% | 769,756 | $37.7M | Reduce -3.4% |
| KYMR Kymera Therapeutics Inc. | 0.60% | 644,590 | $36.5M | Add +14.5% |
| LNG Cheniere Energy Inc. | 0.60% | 154,323 | $36.3M | Add +0.2% |
| TGTX TG Therapeutics Inc. | 0.57% | 954,531 | $34.5M | No change |
| ABVX Abivax SA-ADR | 0.55% | 396,904 | $33.7M | New |
| IP International Paper Co. | 0.54% | 705,797 | $32.7M | Add +4.2% |
| FTDR Frontdoor Inc. | 0.54% | 483,656 | $32.5M | Reduce 0.0% |
| RPRX Royalty Pharma PLC Class A | 0.53% | 916,489 | $32.3M | Reduce -0.6% |
| EQT Eqt Corp. | 0.52% | 582,713 | $31.7M | Add +16.0% |
| SLNO Soleno Therapeutics Inc. | 0.52% | 467,435 | $31.6M | New |
| AIT Applied Industrial Tech Inc. | 0.52% | 120,814 | $31.5M | Add +3.6% |
| EXAS Exact Sciences Corp. | 0.51% | 565,574 | $30.9M | Add +0.0% |
| BBIO Bridgebio Pharma Inc. | 0.50% | 584,296 | $30.3M | Add +52.1% |
| GPI Group 1 Automotive Inc. | 0.50% | 69,166 | $30.3M | Add +4.3% |
| PWR Quanta Services Inc. | 0.47% | 69,330 | $28.7M | Add +0.2% |
| PANW Palo Alto Networks Inc. | 0.47% | 140,897 | $28.7M | Add +6.1% |
| KMTS Kestra Medical Technologies | 0.47% | 1,204,363 | $28.6M | Add +13.6% |
| ESI Element Solutions Inc. | 0.46% | 1,117,834 | $28.1M | Add +3.8% |
| RVMD Revolution Medicines Inc. | 0.46% | 595,038 | $27.8M | Add +59.9% |
| TYL Tyler Technologies Inc. | 0.45% | 51,938 | $27.2M | Add +35.9% |
| ISRG Intuitive Surgical Inc. | 0.44% | 59,362 | $26.5M | Add +0.5% |
| UTHR United Therapeutics Corp. | 0.43% | 62,241 | $26.1M | Add +31.8% |
| CYBR Cyberark Software Ltd./Israel | 0.41% | 51,313 | $24.8M | Reduce -7.7% |
| NI Nisource Inc. | 0.41% | 570,769 | $24.7M | Add +9.5% |
| GKOS Glaukos Corp. | 0.39% | 289,275 | $23.6M | Add +31.1% |
| VCYT Veracyte Inc. | 0.39% | 684,856 | $23.5M | Add +0.0% |
| CEG Constellation Energy | 0.38% | 69,546 | $22.9M | Add +7.5% |
| VITL Vital Farms Inc. | 0.35% | 516,728 | $21.3M | Add +11.3% |
| MTSR Metsera Inc. | 0.34% | 396,160 | $20.7M | No change |
| DTM DT Midstream Inc. | 0.34% | 183,253 | $20.7M | Add +3.8% |
| AKRO Akero Therapeutics Inc. | 0.34% | 435,293 | $20.7M | Add +117.7% |
| AMLX Amylyx Pharmaceuticals Inc. | 0.34% | 1,512,500 | $20.6M | New |
| FLEX Flex Ltd. | 0.34% | 352,624 | $20.4M | Add +445.5% |
| IRON Disc Medicine Inc. | 0.33% | 308,043 | $20.4M | Add +0.0% |
| MSCI MSCI Inc. | 0.33% | 35,300 | $20.0M | Add +4.3% |
| CDW CDW Corp. | 0.32% | 122,685 | $19.6M | Reduce -28.0% |
| INSP Inspire Medical Systems Inc. | 0.31% | 256,658 | $19.0M | Add +63.8% |
Other holdings (1): bonds, preferreds, convertibles and warrants · $666K (not counted above)
| Security | Class | Shares / Principal | Value | Change |
|---|---|---|---|---|
| CELCUITY INC (CELC 2.75 08/01/31) | NOTE 2.750% 8/0 · principal | 500,000 | $666K | New |
Total filed on the 13F, all lines: $6.1B.
Portfolio Sells Q2 2025 → Q3 2025
| VRNA Verona Pharma Ltd. | Reduce -74.9% | 1.19% | −3.30 |
| BPMC Blueprint Medicines Corp. | Sold out | 0.00% | −1.64 |
| WDAY Workday Inc. Class A | Reduce -88.8% | 0.06% | −0.51 |
| MNDY Monday.com Ltd. | Reduce -35.4% | 0.30% | −0.49 |
| RELY Remitly Global Inc. | Sold out | 0.00% | −0.47 |
| TTD Trade Desk Inc./the Class A | Reduce -55.5% | 0.19% | −0.47 |
| ROP Roper Technologies Inc. | Reduce -0.0% | 1.49% | −0.32 |
| TMDX Transmedics Group Inc. | Reduce -0.0% | 1.01% | −0.28 |
| EXLS Exlservice Holdings Inc. | Reduce -89.6% | 0.03% | −0.27 |
| PCVX Vaxcyte Inc. | Reduce -55.3% | 0.22% | −0.26 |
| FICO Fair Isaac Corp. | Sold out | 0.00% | −0.25 |
| CRWD CrowdStrike Holdings Inc. Class A | Reduce -54.0% | 0.18% | −0.25 |
| AVB Avalonbay Communities Inc. | Sold out | 0.00% | −0.24 |
| MKC McCormick & Co.-Non VTG SHRS | Reduce -93.5% | 0.01% | −0.23 |
| CDW CDW Corp. | Reduce -28.0% | 0.32% | −0.21 |
| BRKR Bruker Corp. | Sold out | 0.00% | −0.20 |
| POOL Pool Corp. | Reduce -95.3% | 0.01% | −0.20 |
| VST Vistra Corp. | Reduce -4.8% | 1.49% | −0.16 |
| ELS Equity Lifestyle Properties | Sold out | 0.00% | −0.16 |
| LAD Lithia Motors Inc. | Reduce -2.2% | 0.94% | −0.15 |
| VMRK Vivmark Residential | Reduce -31.2% | 0.15% | −0.14 |
| RLI Rli Corp. | Sold out | 0.00% | −0.14 |
| UNP Union Pacific Corp. | Reduce -77.0% | 0.03% | −0.10 |
| NTNX Nutanix Inc. Class A | Reduce -3.4% | 0.75% | −0.10 |
| SRRK Scholar Rock Holding Corp. | Reduce -3.9% | 1.71% | −0.09 |
| BHVN Biohaven Ltd. | Sold out | 0.00% | −0.07 |
| ACAD Acadia Pharmaceuticals Inc. | Reduce -21.0% | 0.20% | −0.07 |
| PEG Public Service Enterprise GP | Reduce -12.8% | 0.27% | −0.07 |
| FITB Fifth Third Bancorp | Reduce -78.6% | 0.01% | −0.06 |
| IEX Idex Corp. | Reduce -5.3% | 0.26% | −0.06 |
| RPRX Royalty Pharma PLC Class A | Reduce -0.6% | 0.53% | −0.05 |
| SAP Sap SE-Sponsored ADR | Reduce -4.7% | 0.11% | −0.03 |
| AIP Arteris Inc. | Sold out | 0.00% | −0.03 |
| PRVA Privia Health Group Inc. | Reduce -10.3% | 0.30% | −0.03 |
| SNV Synovus Financial Corp. | Reduce -70.0% | 0.01% | −0.03 |
| DT Dynatrace Inc. | Reduce -78.9% | 0.01% | −0.02 |
| TW Tradeweb Markets Inc. Class A | Reduce -75.4% | 0.00% | −0.02 |
| KD Kyndryl Holdings Inc. | Sold out | 0.00% | −0.02 |
| PCTY Paylocity Holding Corp. | Sold out | 0.00% | −0.02 |
| CFLT Confluent Inc. Class A | Sold out | 0.00% | −0.02 |
| AMT American Tower Corp. | Reduce -16.4% | 0.04% | −0.02 |
| SNPS Synopsys Inc. | Sold out | 0.00% | −0.02 |
| ENTG Entegris Inc. | Sold out | 0.00% | −0.02 |
| APD Air Products & Chemicals Inc. | Reduce -25.5% | 0.03% | −0.02 |
| PGR Progressive Corp. | Reduce -11.7% | 0.05% | −0.02 |
| MANH Manhattan Associates Inc. | Reduce -73.0% | 0.01% | −0.02 |
| ZS Zscaler Inc. | Reduce -53.8% | 0.01% | −0.02 |
| AVPT Avepoint Inc. | Sold out | 0.00% | −0.01 |
| EMR Emerson Electric Co. | Sold out | 0.00% | −0.01 |
| RSG Republic Services Inc. | Reduce -12.0% | 0.04% | −0.01 |
Portfolio Buys Q2 2025 → Q3 2025
| TLN Talen Energy Corp. | Add +282.3% | 0.78% | +0.63 |
| ABVX Abivax SA-ADR | New | 0.55% | +0.55 |
| SLNO Soleno Therapeutics Inc. | New | 0.52% | +0.52 |
| BBNX Beta Bionics Inc. | Add +0.5% | 1.62% | +0.36 |
| AMLX Amylyx Pharmaceuticals Inc. | New | 0.34% | +0.34 |
| CLDX Celldex Therapeutics Inc. | Add +37.1% | 0.79% | +0.31 |
| MDB Mongodb Inc. | Add +3968.7% | 0.29% | +0.28 |
| FLEX Flex Ltd. | Add +445.5% | 0.34% | +0.28 |
| PLD Prologis Inc. | Add +72.9% | 0.66% | +0.28 |
| DHI D.R. Horton Inc. | Add +3.1% | 1.27% | +0.27 |
| BLTE Belite Bio Inc. - ADR | New | 0.24% | +0.24 |
| LSCC Lattice Semiconductor Corp. | Add +3.1% | 0.74% | +0.23 |
| RVMD Revolution Medicines Inc. | Add +59.9% | 0.46% | +0.22 |
| BBIO Bridgebio Pharma Inc. | Add +52.1% | 0.50% | +0.21 |
| URI United Rentals Inc. | Add +0.5% | 1.26% | +0.21 |
| BBOT Bridgebio Oncology Therapeut | New | 0.20% | +0.20 |
| KLAC KLA Corp. | Add +17.5% | 0.82% | +0.20 |
| NVT Nvent Electric PLC | Add +1.9% | 0.88% | +0.20 |
| SITM Sitime Corp. | Add +0.8% | 0.77% | +0.19 |
| UTHR United Therapeutics Corp. | Add +31.8% | 0.43% | +0.19 |
| KYMR Kymera Therapeutics Inc. | Add +14.5% | 0.60% | +0.17 |
| AXSM Axsome Therapeutics Inc. | Add +2.9% | 1.49% | +0.16 |
| KMTS Kestra Medical Technologies | Add +13.6% | 0.47% | +0.16 |
| STX Seagate Technology Holdings | New | 0.16% | +0.16 |
| AKRO Akero Therapeutics Inc. | Add +117.7% | 0.34% | +0.15 |
| CHWY Chewy Inc. Class A | Add +32.2% | 0.94% | +0.14 |
| HBAN Huntington Bancshares Inc. | Add +30.6% | 0.69% | +0.14 |
| NDAQ Nasdaq Inc. | Add +23.8% | 0.98% | +0.13 |
| ETR Entergy Corp. | Add +9.8% | 1.00% | +0.13 |
| HLI Houlihan Lokey Inc. | Add +12.8% | 0.74% | +0.13 |
| RF Regions Financial Corp. | Add +112.4% | 0.23% | +0.12 |
| LFUS Littelfuse Inc. | New | 0.12% | +0.12 |
| OCUL Ocular Therapeutix Inc. | New | 0.11% | +0.11 |
| ORLY O'reilly Automotive Inc. | Add +0.9% | 0.94% | +0.11 |
| LOW Lowe's Cos Inc. | Add +12.8% | 0.67% | +0.11 |
| CDTX Cidara Therapeutics Inc. | New | 0.10% | +0.10 |
| FERG Ferguson Enterprises Inc. | Add +18.9% | 0.66% | +0.09 |
| CAT Caterpillar Inc. | New | 0.09% | +0.09 |
| RNAM Avidity Biosciences Inc. | Add +0.0% | 0.27% | +0.08 |
| ROL Rollins Inc. | Add +15.1% | 0.69% | +0.08 |
| EVH Evolent Health Inc. Class A | Add +54.0% | 0.88% | +0.07 |
| VCYT Veracyte Inc. | Add +0.0% | 0.39% | +0.06 |
| TYL Tyler Technologies Inc. | Add +35.9% | 0.45% | +0.05 |
| IRON Disc Medicine Inc. | Add +0.0% | 0.33% | +0.05 |
| HTFL Heartflow Inc. | New | 0.05% | +0.05 |
| AIT Applied Industrial Tech Inc. | Add +3.6% | 0.52% | +0.04 |
| AXP American Express Co. | Add +22.2% | 0.28% | +0.04 |
| NOW ServiceNow Inc. | Add +63.7% | 0.15% | +0.04 |
| MDT Medtronic PLC | Add +93.0% | 0.08% | +0.04 |
| MSI Motorola Solutions Inc. | Add +4.3% | 0.64% | +0.04 |
Notes & Other Activity Q2 2025 → Q3 2025
| CELCUITY INC (CELC 2.75 08/01/31) | NOTE 2.750% 8/0 · principal | New | 500,000 | $666K |
Bonds, preferreds, convertibles and warrants; not part of the stock holdings or percentages above.
All Filings
| Quarter | Positions | 13F Reported Value | Top Holdings |
|---|---|---|---|
| Q2 2026 | 301 | $7.5B | GH, LRCX, XMTR, TT, MIRM |
| Q1 2026 | 278 | $6.0B | GH, TT, LRCX, MIRM, TRGP |
| Q4 2025 | 268 | $6.4B | GH, XMTR, MIRM, TT, BBNX |
| Q3 2025 | 239 | $6.1B | GH, MIRM, XMTR, TT, INSM |
| Q2 2025 | 237 | $5.7B | VRNA, GH, TT, MIRM, INSM |
| Q1 2025 | 217 | $5.0B | VRNA, GH, TT, MIRM, ROP |
| Q4 2024 | 204 | $5.5B | VRNA, TT, XMTR, GH, SRRK |
| Q3 2024 | 180 | $5.8B | TT, DHI, ODFL, ROP, WCN |
| Q2 2024 | 159 | $5.8B | TT, TMDX, WCN, ROP, ODFL |
| Q1 2024 | 156 | $6.4B | TT, ZNTL, SWAV, ODFL, ROP |