Eventide Asset Management, LLC

In its 13F for Q1 2026 (holdings as of March 31, 2026, filed May 15, 2026), Eventide Asset Management, LLC reported 278 stock positions worth $6.0 billion. Its top holding was Guardant Health (GH) at 3.6% of the portfolio, followed by Trane Technologies (TT, 2.8%) and Lam Research (LRCX, 2.4%). Compared with Q4 2025, it opened 46 new positions, sold out of 36, added to 155 and reduced 70. The biggest buy was Generac (GNRC, shares +227%) and the biggest sale Roper Technologies (ROP, shares −48%).

Most Recent 13F
Q2 2026
Location
Boston, MA
CIK
0001442891
Portfolio Value
$6.0B (Q1 2026)
SEC Filing
0001580642-26-003193 ↗ filed May 15, 2026

Holdings Value

0$2.0B$4.0B$6.0B$8.0B Q1 2024: $6.4B Q1 2024 Q2 2024: $5.8B Q2 2024 Q3 2024: $5.8B Q3 2024 Q4 2024: $5.5B Q4 2024 Q1 2025: $5.0B Q1 2025 Q2 2025: $5.7B Q2 2025 Q3 2025: $6.1B Q3 2025 Q4 2025: $6.4B Q4 2025 Q1 2026: $6.0B $6.0B Q1 2026 Q2 2026: $7.5B Q2 2026

Holdings 278 stocks · $6.0B

GH Guardant Health Inc. 3.61% 2,362,379 $218.1M Reduce -5.9%
TT Trane Technologies PLC 2.80% 406,555 $169.0M Add +0.8%
LRCX Lam Research Corp. 2.42% 688,402 $146.6M Add +2.9%
MIRM Mirum Pharmaceuticals Inc. 2.15% 1,408,871 $130.1M Reduce -32.7%
TRGP Targa Resources Corp. 2.08% 502,287 $125.8M Add +4.5%
XMTR Xometry Inc. Class A 2.00% 2,960,239 $120.8M Add +0.8%
GEV GE Vernova Inc. 1.91% 133,200 $115.6M Reduce -28.8%
ODFL Old Dominion Freight Line 1.91% 591,691 $115.5M Reduce -3.1%
SRRK Scholar Rock Holding Corp. 1.78% 2,197,385 $107.9M Reduce -9.6%
ARGX Argenx SE - ADR 1.52% 125,657 $91.7M Add +3.7%
ASML ASML Holding NV-NY Reg SHS filed as ASML HLDG NV 1.49% 68,110 $89.9M Add +1.9%
IRTC Irhythm Holdings Inc. 1.48% 760,825 $89.8M Add +9.9%
INSM Insmed Inc. 1.48% 546,310 $89.3M Add +13.0%
AXSM Axsome Therapeutics Inc. 1.45% 519,558 $87.8M Reduce -9.1%
PCVX Vaxcyte Inc. 1.32% 1,374,292 $79.8M Add +49.9%
ETR Entergy Corp. 1.27% 682,847 $76.5M Add +1.4%
VST Vistra Corp. 1.22% 492,711 $74.0M Add +1.0%
URI United Rentals Inc. 1.18% 97,795 $71.2M Add +1.9%
LBRT Liberty Energy Inc. 1.14% 2,403,098 $69.2M Add +22.0%
TOST Toast Inc. Class A 1.09% 2,488,669 $66.0M Add +0.1%
MTD Mettler-Toledo International 1.06% 50,751 $64.0M Add +1.0%
MPWR Monolithic Power Systems Inc. 1.05% 58,154 $63.4M Reduce -14.9%
RPRX Royalty Pharma PLC Class A 1.04% 1,312,534 $62.6M Add +1.2%
NVT Nvent Electric PLC 1.02% 523,557 $61.6M Add +1.7%
WMB Williams Cos Inc. 1.00% 832,248 $60.5M Add +4.9%
NDAQ Nasdaq Inc. 1.00% 711,839 $60.2M Add +0.7%
GNRC Generac Holdings Inc. 0.99% 306,838 $59.9M Add +226.9%
BBNX Beta Bionics Inc. 0.99% 5,945,488 $59.6M Add +19.0%
DHI D.R. Horton Inc. 0.98% 430,871 $59.0M Add +0.9%
KLAC KLA Corp. 0.96% 39,639 $57.8M Reduce -12.5%
BLTE Belite Bio Inc. - ADR 0.94% 357,650 $57.0M Reduce -6.6%
LSCC Lattice Semiconductor Corp. 0.94% 611,138 $56.6M Reduce -1.6%
PLD Prologis Inc. 0.93% 427,133 $56.1M Add +1.5%
TMDX Transmedics Group Inc. 0.90% 548,824 $54.5M Add +0.1%
DTM DT Midstream Inc. 0.90% 401,951 $54.1M Add +1.8%
NI Nisource Inc. 0.88% 1,143,590 $53.3M Add +0.9%
KYMR Kymera Therapeutics Inc. 0.86% 626,925 $52.2M Add +0.1%
RBA RB Global Inc. 0.84% 528,143 $50.6M Add +0.1%
WCN Waste Connections Inc. 0.83% 309,927 $50.3M Reduce -0.1%
ORLY O'reilly Automotive Inc. 0.82% 539,880 $49.8M Reduce -0.4%
PWR Quanta Services Inc. 0.81% 89,386 $49.0M Add +0.5%
COLL Collegium Pharmaceutical Inc. 0.78% 1,424,282 $47.1M Reduce -24.1%
APGE Apogee Therapeutics Inc. 0.78% 557,423 $46.9M Add +27.8%
VMC Vulcan Materials Co. 0.76% 169,572 $46.2M Add +0.1%
NVDA Nvidia Corp. 0.74% 259,419 $44.7M Add +8.4%
EGP Eastgroup Properties Inc. 0.72% 235,730 $43.6M Reduce -0.2%
IONS Ionis Pharmaceuticals Inc. 0.71% 575,000 $43.2M No change
STE Steris PLC 0.71% 194,635 $43.0M Add +2.2%
PANW Palo Alto Networks Inc. 0.67% 252,151 $40.4M Add +72.8%
LOW Lowe's Cos Inc. 0.67% 170,635 $40.2M Add +0.0%
ROL Rollins Inc. 0.67% 753,499 $40.2M Add +1.9%
ESI Element Solutions Inc. 0.66% 1,171,467 $39.8M Add +1.9%
FERG Ferguson Enterprises Inc. 0.65% 169,460 $39.3M Add +0.7%
HBAN Huntington Bancshares Inc. 0.65% 2,533,502 $39.3M Reduce -0.3%
CHWY Chewy Inc. Class A 0.63% 1,412,290 $38.1M Reduce -0.0%
TER Teradyne Inc. 0.62% 127,466 $37.6M Add +229.9%
GLBE Global-E Online Ltd. 0.62% 1,218,345 $37.6M Add +0.1%
TLN Talen Energy Corp. 0.62% 117,183 $37.4M Reduce -6.0%
FAST Fastenal Co. 0.61% 797,585 $36.9M Add +2.6%
ABVX Abivax SA-ADR 0.59% 320,576 $35.7M Reduce -2.2%
ROP Roper Technologies Inc. 0.56% 95,661 $33.8M Reduce -48.1%
HLI Houlihan Lokey Inc. 0.56% 236,136 $33.8M Add +0.7%
CLDX Celldex Therapeutics Inc. 0.54% 1,037,000 $32.9M Reduce -36.9%
BBIO Bridgebio Pharma Inc. 0.54% 437,130 $32.5M Add +20.7%
AIT Applied Industrial Tech Inc. 0.53% 121,287 $32.1M Add +1.6%
CYTK Cytokinetics Inc. 0.52% 479,098 $31.6M Reduce -0.1%
TRVI Trevi Therapeutics Inc. 0.52% 2,622,306 $31.3M No change
DXCM Dexcom Inc. 0.51% 495,003 $31.1M Add +4.4%
AXON Axon Enterprise Inc. 0.49% 69,843 $29.6M Reduce -1.2%
WGS Genedx Holdings Corp. 0.49% 459,015 $29.5M New
PVLA Palvella Therapeutics Inc. 0.48% 233,248 $29.0M Add +129.2%
KMTS Kestra Medical Technologies 0.48% 1,445,864 $28.8M Add +13.9%
DDOG Datadog Inc. Class A 0.47% 239,835 $28.3M Add +0.4%
CELC Celcuity Inc. 0.46% 243,899 $27.8M Reduce -22.3%
EVMN Evommune Inc. 0.46% 1,209,129 $27.8M Add +25.8%
ISRG Intuitive Surgical Inc. 0.46% 59,942 $27.6M Add +0.9%
MSCI MSCI Inc. 0.45% 51,068 $27.5M Add +40.8%
BKR Baker Hughes Co. 0.44% 438,017 $26.7M Add +25.2%
MBX MBX Biosciences Inc. 0.44% 890,000 $26.6M No change
CNTA Centessa Pharmaceuticals Ltd. 0.44% 668,142 $26.5M New
SION Sionna Therapeutics Inc. 0.43% 645,530 $25.9M Add +1.0%
FTDR Frontdoor Inc. 0.42% 486,232 $25.7M Add +0.2%
EQT Eqt Corp. 0.42% 399,975 $25.5M Reduce -2.4%
SITM Sitime Corp. 0.42% 73,665 $25.4M Reduce -52.8%
RVMD Revolution Medicines Inc. 0.42% 261,425 $25.4M Reduce -30.9%
IRON Disc Medicine Inc. 0.42% 395,572 $25.3M Add +0.1%
CGON CG Oncology Inc. 0.41% 369,985 $25.0M Add +18.4%
WEC WEC Energy Group Inc. 0.40% 209,072 $24.2M Add +1.1%
VRT Vertiv Holdings Co. Class A 0.39% 95,010 $23.8M Reduce -10.4%
IMMX Immix Biopharma Inc. 0.38% 2,549,019 $23.2M No change
ARWR Arrowhead Pharmaceuticals Inc. 0.38% 370,000 $23.2M No change
IP International Paper Co. 0.38% 645,438 $23.0M Reduce -11.1%
ULS Ul Solutions Inc. Class A 0.38% 267,774 $22.8M New
MSI Motorola Solutions Inc. 0.38% 52,581 $22.8M Reduce -29.0%
SHW The Sherwin-Williams Co. 0.38% 71,124 $22.8M Add +0.7%
PNR Pentair PLC 0.37% 259,595 $22.5M Reduce -20.4%
HAL Halliburton Co. 0.37% 568,546 $22.2M Add +770.1%
CEG Constellation Energy 0.37% 78,108 $22.1M Add +5.5%
OVID Ovid Therapeutics Inc. 0.36% 9,916,911 $22.0M Add +131.4%
ADCT Adc Therapeutics SA 0.35% 5,701,655 $21.4M Add +69.5%

Show all 278 holdings

Portfolio Sells Q4 2025 → Q1 2026

ROP Roper Technologies Inc. Reduce -48.1% 0.56% −0.72
LAD Lithia Motors Inc. Reduce -72.8% 0.18% −0.64
INSP Inspire Medical Systems Inc. Sold out 0.00% −0.63
RNAM Avidity Biosciences Inc. Sold out 0.00% −0.59
COLL Collegium Pharmaceutical Inc. Reduce -24.1% 0.78% −0.58
SITM Sitime Corp. Reduce -52.8% 0.42% −0.44
MIRM Mirum Pharmaceuticals Inc. Reduce -32.7% 2.15% −0.43
SNDX Syndax Pharmaceuticals Inc. Sold out 0.00% −0.41
EXAS Exact Sciences Corp. Sold out 0.00% −0.40
GH Guardant Health Inc. Reduce -5.9% 3.61% −0.40
VCYT Veracyte Inc. Sold out 0.00% −0.38
TYL Tyler Technologies Inc. Reduce -97.3% 0.01% −0.37
CYBR Cyberark Software Ltd./Israel Sold out 0.00% −0.35
TGTX TG Therapeutics Inc. Sold out 0.00% −0.33
AJG Arthur J Gallagher & Co. Reduce -40.2% 0.30% −0.27
VITL Vital Farms Inc. Sold out 0.00% −0.26
GKOS Glaukos Corp. Reduce -48.1% 0.27% −0.24
HUBS HubSpot Inc. Reduce -7.8% 0.33% −0.23
OLMA Olema Pharmaceuticals Inc. Sold out 0.00% −0.22
MNDY Monday.com Ltd. Sold out 0.00% −0.21
MAZE Maze Therapeutics Inc. Sold out 0.00% −0.21
DYN Dyne Therapeutics Inc. Sold out 0.00% −0.21
ALNY Alnylam Pharmaceuticals Inc. Reduce -96.7% 0.01% −0.21
QURE Uniqure NV Sold out 0.00% −0.19
AXSM Axsome Therapeutics Inc. Reduce -9.1% 1.45% −0.18
VRSK Verisk Analytics Inc. Sold out 0.00% −0.17
PNR Pentair PLC Reduce -20.4% 0.37% −0.16
GPI Group 1 Automotive Inc. Reduce -32.9% 0.23% −0.16
IDYA Ideaya Biosciences Inc. Sold out 0.00% −0.15
PEG Public Service Enterprise GP Reduce -96.3% 0.01% −0.15
CLDX Celldex Therapeutics Inc. Reduce -36.9% 0.54% −0.15
EWTX Edgewise Therapeutics Inc. Reduce -73.6% 0.08% −0.14
AXON Axon Enterprise Inc. Reduce -1.2% 0.49% −0.14
ENGN Engene Holdings Inc. Sold out 0.00% −0.13
WVE Wave Life Sciences Ltd. Sold out 0.00% −0.13
BBOT Bridgebio Oncology Therapeut Reduce -50.0% 0.08% −0.13
TTAN Servicetitan Inc. Class A Reduce -8.8% 0.17% −0.13
SPGI S&P Global Inc. Reduce -49.0% 0.10% −0.12
TLN Talen Energy Corp. Reduce -6.0% 0.62% −0.11
AXP American Express Co. Reduce -26.2% 0.18% −0.11
PRAX Praxis Precision Medicines I Reduce -42.4% 0.21% −0.10
NOW ServiceNow Inc. Reduce -48.5% 0.06% −0.10
ABVX Abivax SA-ADR Reduce -2.2% 0.59% −0.10
CHWY Chewy Inc. Class A Reduce -0.0% 0.63% −0.10
TTD Trade Desk Inc./the Class A Sold out 0.00% −0.08
UTHR United Therapeutics Corp. Reduce -39.3% 0.28% −0.08
FLEX Flex Ltd. Reduce -42.0% 0.14% −0.07
IP International Paper Co. Reduce -11.1% 0.38% −0.07
MSI Motorola Solutions Inc. Reduce -29.0% 0.38% −0.07
RVMD Revolution Medicines Inc. Reduce -30.9% 0.42% −0.05

Portfolio Buys Q4 2025 → Q1 2026

GNRC Generac Holdings Inc. Add +226.9% 0.99% +0.79
TRGP Targa Resources Corp. Add +4.5% 2.08% +0.69
PCVX Vaxcyte Inc. Add +49.9% 1.32% +0.66
LRCX Lam Research Corp. Add +2.9% 2.42% +0.63
LBRT Liberty Energy Inc. Add +22.0% 1.14% +0.58
TER Teradyne Inc. Add +229.9% 0.62% +0.50
WGS Genedx Holdings Corp. New 0.49% +0.49
CNTA Centessa Pharmaceuticals Ltd. New 0.44% +0.44
ULS Ul Solutions Inc. Class A New 0.38% +0.38
ASML ASML Holding NV-NY Reg SHS Add +1.9% 1.49% +0.37
TT Trane Technologies PLC Add +0.8% 2.80% +0.34
HAL Halliburton Co. Add +770.1% 0.37% +0.34
PVLA Palvella Therapeutics Inc. Add +129.2% 0.48% +0.31
DNTH Dianthus Therapeutics Inc. New 0.31% +0.31
WTW Willis Towers Watson PLC New 0.30% +0.30
STRO Sutro Biopharma Inc. New 0.29% +0.29
ETR Entergy Corp. Add +1.4% 1.27% +0.29
EYPT Eyepoint Inc. New 0.27% +0.27
APGE Apogee Therapeutics Inc. Add +27.8% 0.78% +0.26
WMB Williams Cos Inc. Add +4.9% 1.00% +0.26
OVID Ovid Therapeutics Inc. Add +131.4% 0.36% +0.26
RPRX Royalty Pharma PLC Class A Add +1.2% 1.04% +0.25
PANW Palo Alto Networks Inc. Add +72.8% 0.67% +0.25
PWR Quanta Services Inc. Add +0.5% 0.81% +0.22
DFTX Definium Therapeutics Inc. New 0.21% +0.21
CGON CG Oncology Inc. Add +18.4% 0.41% +0.21
ESI Element Solutions Inc. Add +1.9% 0.66% +0.21
EVMN Evommune Inc. Add +25.8% 0.46% +0.20
NVT Nvent Electric PLC Add +1.7% 1.02% +0.20
FANG Diamondback Energy Inc. Add +547.3% 0.22% +0.20
BKR Baker Hughes Co. Add +25.2% 0.44% +0.19
OCS Oculis Holding AG New 0.19% +0.19
DELL Dell Technologies -C Add +103.6% 0.26% +0.17
ADCT Adc Therapeutics SA Add +69.5% 0.35% +0.17
INSM Insmed Inc. Add +13.0% 1.48% +0.16
DTM DT Midstream Inc. Add +1.8% 0.90% +0.16
AKTS Aktis Oncology Inc. New 0.15% +0.15
FN Fabrinet Add +81.8% 0.27% +0.14
LITE Lumentum Holdings Inc. Add +200.0% 0.17% +0.14
NI Nisource Inc. Add +0.9% 0.88% +0.14
CRVS Corvus Pharmaceuticals Inc. New 0.13% +0.13
STX Seagate Technology Holdings Add +1413.8% 0.14% +0.13
MSCI MSCI Inc. Add +40.8% 0.45% +0.13
BE Bloom Energy Corp. Class A Add +0.4% 0.31% +0.12
FAST Fastenal Co. Add +2.6% 0.61% +0.12
COHR Coherent Corp. Add +313.2% 0.15% +0.12
BBIO Bridgebio Pharma Inc. Add +20.7% 0.54% +0.10
KYMR Kymera Therapeutics Inc. Add +0.1% 0.86% +0.10
RLMD Relmada Therapeutics Inc. New 0.10% +0.10
EVH Evolent Health Inc. Class A New 0.10% +0.10

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 301$7.5BGH, LRCX, XMTR, TT, MIRM
Q1 2026 278$6.0BGH, TT, LRCX, MIRM, TRGP
Q4 2025 268$6.4BGH, XMTR, MIRM, TT, BBNX
Q3 2025 239$6.1BGH, MIRM, XMTR, TT, INSM
Q2 2025 237$5.7BVRNA, GH, TT, MIRM, INSM
Q1 2025 217$5.0BVRNA, GH, TT, MIRM, ROP
Q4 2024 204$5.5BVRNA, TT, XMTR, GH, SRRK
Q3 2024 180$5.8BTT, DHI, ODFL, ROP, WCN
Q2 2024 159$5.8BTT, TMDX, WCN, ROP, ODFL
Q1 2024 156$6.4BTT, ZNTL, SWAV, ODFL, ROP