Eventide Asset Management, LLC
In its 13F for Q4 2025 (holdings as of December 31, 2025, filed February 13, 2026), Eventide Asset Management, LLC reported 268 stock positions worth $6.4 billion. Its top holding was Guardant Health (GH) at 4.0% of the portfolio, followed by Xometry Class A (XMTR, 2.7%) and Mirum Pharmaceuticals (MIRM, 2.6%). Compared with Q3 2025, it opened 50 new positions, sold out of 21, added to 129 and reduced 80. The biggest buy was Beta Bionics (BBNX, shares +1%) and the biggest sale an exit from Verona Pharma (VRNA).
- Most Recent 13F
- Q2 2026
- Location
- Boston, MA
- CIK
- 0001442891
- Portfolio Value
- $6.4B (Q4 2025)
- SEC Filing
- 0001580642-26-001080 ↗ filed Feb 13, 2026
Holdings Value
Holdings 268 stocks · $6.4B
| GH Guardant Health Inc. | 4.01% | 2,511,091 | $256.5M | Reduce -24.4% |
| XMTR Xometry Inc. Class A | 2.73% | 2,936,126 | $174.7M | Reduce -5.8% |
| MIRM Mirum Pharmaceuticals Inc. | 2.58% | 2,093,582 | $165.4M | Reduce -17.0% |
| TT Trane Technologies PLC | 2.45% | 403,274 | $157.0M | Add +1.2% |
| BBNX Beta Bionics Inc. | 2.38% | 4,994,728 | $152.2M | Add +0.8% |
| IRTC Irhythm Holdings Inc. | 1.92% | 692,486 | $122.9M | Add +0.1% |
| GEV GE Vernova Inc. | 1.91% | 187,122 | $122.4M | Reduce -2.9% |
| LRCX Lam Research Corp. | 1.79% | 669,089 | $114.6M | Reduce -26.0% |
| SRRK Scholar Rock Holding Corp. | 1.67% | 2,431,333 | $107.1M | Reduce -13.2% |
| AXSM Axsome Therapeutics Inc. | 1.63% | 571,226 | $104.2M | Reduce -23.5% |
| ARGX Argenx SE - ADR | 1.59% | 121,221 | $101.9M | Reduce -3.3% |
| ODFL Old Dominion Freight Line | 1.50% | 610,644 | $95.8M | Add +0.7% |
| TRGP Targa Resources Corp. | 1.39% | 480,550 | $88.7M | Add +27.9% |
| TOST Toast Inc. Class A | 1.38% | 2,486,040 | $88.3M | Add +0.2% |
| COLL Collegium Pharmaceutical Inc. | 1.36% | 1,876,239 | $86.9M | Reduce -21.5% |
| INSM Insmed Inc. | 1.31% | 483,589 | $84.2M | Reduce -51.9% |
| ROP Roper Technologies Inc. | 1.28% | 184,166 | $82.0M | Add +1.2% |
| VST Vistra Corp. | 1.23% | 487,636 | $78.7M | Add +5.4% |
| URI United Rentals Inc. | 1.21% | 95,940 | $77.7M | Add +19.6% |
| ASML ASML Holding NV-NY Reg SHS | 1.12% | 66,820 | $71.5M | Add +1.1% |
| MTD Mettler-Toledo International | 1.10% | 50,258 | $70.1M | Add +1.6% |
| NDAQ Nasdaq Inc. | 1.07% | 707,048 | $68.8M | Add +4.8% |
| TMDX Transmedics Group Inc. | 1.04% | 548,267 | $66.7M | Add +0.2% |
| ETR Entergy Corp. | 0.97% | 673,082 | $62.3M | Add +3.4% |
| MPWR Monolithic Power Systems Inc. | 0.97% | 68,373 | $62.0M | Add +65.8% |
| DHI D.R. Horton Inc. | 0.96% | 427,045 | $61.5M | Reduce -6.3% |
| BLTE Belite Bio Inc. - ADR | 0.96% | 383,091 | $61.3M | Add +96.1% |
| KLAC KLA Corp. | 0.86% | 45,282 | $55.2M | Reduce -2.7% |
| SITM Sitime Corp. | 0.86% | 155,983 | $55.1M | Add +0.2% |
| WCN Waste Connections Inc. | 0.85% | 310,111 | $54.4M | Add +0.2% |
| RBA RB Global Inc. | 0.85% | 527,595 | $54.3M | Add +0.2% |
| PLD Prologis Inc. | 0.84% | 420,834 | $53.9M | Add +20.2% |
| NVT Nvent Electric PLC | 0.82% | 514,890 | $52.6M | Reduce -4.9% |
| LAD Lithia Motors Inc. | 0.81% | 156,374 | $52.0M | Reduce -13.7% |
| RPRX Royalty Pharma PLC Class A | 0.78% | 1,296,826 | $50.2M | Add +41.5% |
| ORLY O'reilly Automotive Inc. | 0.77% | 541,867 | $49.4M | Add +1.6% |
| KYMR Kymera Therapeutics Inc. | 0.76% | 626,430 | $48.7M | Reduce -2.8% |
| STE Steris PLC | 0.75% | 190,483 | $48.3M | Add +8.8% |
| VMC Vulcan Materials Co. | 0.75% | 169,367 | $48.3M | Add +0.8% |
| GLBE Global-E Online Ltd. | 0.75% | 1,217,689 | $47.9M | Add +0.2% |
| WMB Williams Cos Inc. | 0.74% | 793,160 | $47.7M | Reduce -26.9% |
| NI Nisource Inc. | 0.74% | 1,133,220 | $47.3M | Add +98.5% |
| DTM DT Midstream Inc. | 0.74% | 394,724 | $47.3M | Add +115.4% |
| TLN Talen Energy Corp. | 0.73% | 124,596 | $46.7M | Add +11.5% |
| CHWY Chewy Inc. Class A | 0.73% | 1,412,717 | $46.7M | Add +0.3% |
| LSCC Lattice Semiconductor Corp. | 0.71% | 621,156 | $45.7M | Add +1.8% |
| IONS Ionis Pharmaceuticals Inc. | 0.71% | 575,000 | $45.5M | New |
| NVDA Nvidia Corp. | 0.70% | 239,284 | $44.7M | Add +0.3% |
| CLDX Celldex Therapeutics Inc. | 0.70% | 1,642,559 | $44.6M | Reduce -11.7% |
| ROL Rollins Inc. | 0.69% | 739,746 | $44.4M | Add +2.9% |
| ABVX Abivax SA-ADR | 0.69% | 327,911 | $44.2M | Reduce -17.4% |
| HBAN Huntington Bancshares Inc. | 0.69% | 2,540,661 | $44.2M | Add +5.0% |
| PCVX Vaxcyte Inc. | 0.66% | 917,115 | $42.3M | Add +141.8% |
| EGP Eastgroup Properties Inc. | 0.66% | 236,158 | $42.1M | Reduce -3.3% |
| LOW Lowe's Cos Inc. | 0.64% | 170,628 | $41.2M | Add +5.0% |
| HLI Houlihan Lokey Inc. | 0.64% | 234,404 | $40.9M | Add +6.5% |
| INSP Inspire Medical Systems Inc. | 0.63% | 440,205 | $40.6M | Add +71.5% |
| AXON Axon Enterprise Inc. | 0.63% | 70,702 | $40.2M | Add +2.3% |
| RNAM Avidity Biosciences Inc. | 0.59% | 524,643 | $37.8M | Add +39.5% |
| PWR Quanta Services Inc. | 0.59% | 88,932 | $37.6M | Add +28.3% |
| FERG Ferguson Enterprises Inc. | 0.59% | 168,275 | $37.5M | Reduce -5.9% |
| LBRT Liberty Energy Inc. | 0.57% | 1,970,459 | $36.4M | New |
| AJG Arthur J Gallagher & Co. filed as GALLAGHER ARTHUR J & CO | 0.57% | 139,874 | $36.2M | Reduce -35.5% |
| HUBS HubSpot Inc. | 0.56% | 89,921 | $36.1M | Add +4.2% |
| PNR Pentair PLC | 0.53% | 326,280 | $34.0M | Reduce -17.8% |
| KMTS Kestra Medical Technologies | 0.53% | 1,269,651 | $33.7M | Add +5.4% |
| ISRG Intuitive Surgical Inc. | 0.53% | 59,391 | $33.7M | Add +0.1% |
| APGE Apogee Therapeutics Inc. | 0.51% | 436,015 | $32.9M | New |
| TRVI Trevi Therapeutics Inc. | 0.51% | 2,622,306 | $32.8M | Add +89.8% |
| GKOS Glaukos Corp. | 0.51% | 289,275 | $32.7M | No change |
| DDOG Datadog Inc. Class A | 0.51% | 238,916 | $32.5M | Reduce -31.9% |
| DXCM Dexcom Inc. | 0.49% | 474,310 | $31.5M | New |
| IRON Disc Medicine Inc. | 0.49% | 395,392 | $31.4M | Add +28.4% |
| CELC Celcuity Inc. | 0.49% | 313,679 | $31.3M | Reduce -71.2% |
| FAST Fastenal Co. | 0.49% | 777,666 | $31.3M | Add +1.0% |
| AIT Applied Industrial Tech Inc. | 0.48% | 119,335 | $30.7M | Reduce -1.2% |
| CYTK Cytokinetics Inc. | 0.48% | 479,611 | $30.5M | Add +181.9% |
| RVMD Revolution Medicines Inc. | 0.47% | 378,261 | $30.1M | Reduce -36.4% |
| ESI Element Solutions Inc. | 0.45% | 1,149,146 | $28.7M | Add +2.8% |
| IP International Paper Co. | 0.45% | 726,220 | $28.7M | Add +2.9% |
| MSI Motorola Solutions Inc. | 0.44% | 74,029 | $28.4M | Reduce -13.1% |
| MBX MBX Biosciences Inc. | 0.44% | 890,000 | $28.1M | New |
| FTDR Frontdoor Inc. | 0.44% | 485,161 | $28.0M | Add +0.3% |
| BBIO Bridgebio Pharma Inc. | 0.43% | 362,130 | $27.7M | Reduce -38.0% |
| PANW Palo Alto Networks Inc. | 0.42% | 145,891 | $26.9M | Add +3.5% |
| SION Sionna Therapeutics Inc. | 0.41% | 639,045 | $26.3M | New |
| CEG Constellation Energy | 0.41% | 74,036 | $26.2M | Add +6.5% |
| SNDX Syndax Pharmaceuticals Inc. | 0.41% | 1,238,196 | $26.0M | Add +25.3% |
| EXAS Exact Sciences Corp. | 0.40% | 254,921 | $25.9M | Reduce -54.9% |
| GPI Group 1 Automotive Inc. | 0.39% | 63,823 | $25.2M | Reduce -7.7% |
| NRIX Nurix Therapeutics Inc. | 0.38% | 1,297,893 | $24.6M | New |
| ARWR Arrowhead Pharmaceuticals Inc. | 0.38% | 370,000 | $24.6M | New |
| TYL Tyler Technologies Inc. | 0.38% | 53,185 | $24.2M | Add +2.4% |
| VCYT Veracyte Inc. | 0.38% | 570,720 | $24.0M | Reduce -16.7% |
| MDB Mongodb Inc. | 0.37% | 56,601 | $23.8M | Add +0.2% |
| UTHR United Therapeutics Corp. | 0.36% | 47,004 | $22.9M | Reduce -24.5% |
| SHW The Sherwin-Williams Co. | 0.36% | 70,604 | $22.9M | Reduce -36.6% |
| CYBR Cyberark Software Ltd./Israel | 0.35% | 50,142 | $22.4M | Reduce -2.3% |
| EQT Eqt Corp. | 0.34% | 409,607 | $22.0M | Reduce -29.7% |
| WEC WEC Energy Group Inc. | 0.34% | 206,717 | $21.8M | Add +550.8% |
Portfolio Sells Q3 2025 → Q4 2025
| VRNA Verona Pharma Ltd. | Sold out | 0.00% | −1.19 |
| INSM Insmed Inc. | Reduce -51.9% | 1.31% | −1.07 |
| EVH Evolent Health Inc. Class A | Sold out | 0.00% | −0.88 |
| NTNX Nutanix Inc. Class A | Reduce -99.0% | 0.00% | −0.74 |
| LNG Cheniere Energy Inc. | Reduce -98.6% | 0.01% | −0.59 |
| VRSK Verisk Analytics Inc. | Reduce -73.6% | 0.17% | −0.58 |
| ALNY Alnylam Pharmaceuticals Inc. | Reduce -66.5% | 0.21% | −0.55 |
| AJG Arthur J Gallagher & Co. | Reduce -35.5% | 0.57% | −0.54 |
| SLNO Soleno Therapeutics Inc. | Sold out | 0.00% | −0.52 |
| SO The Southern Co. | Reduce -72.7% | 0.15% | −0.48 |
| MIRM Mirum Pharmaceuticals Inc. | Reduce -17.0% | 2.58% | −0.46 |
| CELC Celcuity Inc. | Reduce -71.2% | 0.49% | −0.40 |
| WMB Williams Cos Inc. | Reduce -26.9% | 0.74% | −0.39 |
| MTSR Metsera Inc. | Sold out | 0.00% | −0.34 |
| AKRO Akero Therapeutics Inc. | Sold out | 0.00% | −0.34 |
| DDOG Datadog Inc. Class A | Reduce -31.9% | 0.51% | −0.31 |
| DHI D.R. Horton Inc. | Reduce -6.3% | 0.96% | −0.31 |
| CDW CDW Corp. | Reduce -93.9% | 0.02% | −0.31 |
| SHW The Sherwin-Williams Co. | Reduce -36.6% | 0.36% | −0.28 |
| PRCT Procept Biorobotics Corp. | Sold out | 0.00% | −0.27 |
| TGTX TG Therapeutics Inc. | Reduce -24.9% | 0.33% | −0.23 |
| ACAD Acadia Pharmaceuticals Inc. | Sold out | 0.00% | −0.20 |
| LRCX Lam Research Corp. | Reduce -26.0% | 1.79% | −0.20 |
| MSI Motorola Solutions Inc. | Reduce -13.1% | 0.44% | −0.20 |
| PNR Pentair PLC | Reduce -17.8% | 0.53% | −0.19 |
| EQT Eqt Corp. | Reduce -29.7% | 0.34% | −0.18 |
| RGEN Repligen Corp. | Sold out | 0.00% | −0.17 |
| RRC Range Resources Corp. | Sold out | 0.00% | −0.16 |
| STX Seagate Technology Holdings | Reduce -96.6% | 0.01% | −0.16 |
| VMRK Vivmark Residential | Sold out | 0.00% | −0.15 |
| RF Regions Financial Corp. | Reduce -61.7% | 0.09% | −0.15 |
| LAD Lithia Motors Inc. | Reduce -13.7% | 0.81% | −0.13 |
| FLEX Flex Ltd. | Reduce -37.5% | 0.21% | −0.13 |
| IDYA Ideaya Biosciences Inc. | Reduce -54.6% | 0.15% | −0.13 |
| LFUS Littelfuse Inc. | Sold out | 0.00% | −0.12 |
| OCUL Ocular Therapeutix Inc. | Sold out | 0.00% | −0.11 |
| PEG Public Service Enterprise GP | Reduce -36.2% | 0.16% | −0.11 |
| TTD Trade Desk Inc./the Class A | Reduce -40.9% | 0.08% | −0.11 |
| GPI Group 1 Automotive Inc. | Reduce -7.7% | 0.39% | −0.10 |
| EXAS Exact Sciences Corp. | Reduce -54.9% | 0.40% | −0.10 |
| CDTX Cidara Therapeutics Inc. | Sold out | 0.00% | −0.10 |
| CLDX Celldex Therapeutics Inc. | Reduce -11.7% | 0.70% | −0.09 |
| MNDY Monday.com Ltd. | Reduce -1.2% | 0.21% | −0.08 |
| FERG Ferguson Enterprises Inc. | Reduce -5.9% | 0.59% | −0.07 |
| UTHR United Therapeutics Corp. | Reduce -24.5% | 0.36% | −0.07 |
| BBIO Bridgebio Pharma Inc. | Reduce -38.0% | 0.43% | −0.07 |
| XMTR Xometry Inc. Class A | Reduce -5.8% | 2.73% | −0.06 |
| SAP Sap SE-Sponsored ADR | Reduce -50.2% | 0.05% | −0.06 |
| CYBR Cyberark Software Ltd./Israel | Reduce -2.3% | 0.35% | −0.06 |
| NVT Nvent Electric PLC | Reduce -4.9% | 0.82% | −0.06 |
Portfolio Buys Q3 2025 → Q4 2025
| BBNX Beta Bionics Inc. | Add +0.8% | 2.38% | +0.76 |
| BLTE Belite Bio Inc. - ADR | Add +96.1% | 0.96% | +0.72 |
| IONS Ionis Pharmaceuticals Inc. | New | 0.71% | +0.71 |
| LBRT Liberty Energy Inc. | New | 0.57% | +0.57 |
| APGE Apogee Therapeutics Inc. | New | 0.51% | +0.51 |
| DXCM Dexcom Inc. | New | 0.49% | +0.49 |
| MBX MBX Biosciences Inc. | New | 0.44% | +0.44 |
| PCVX Vaxcyte Inc. | Add +141.8% | 0.66% | +0.44 |
| SION Sionna Therapeutics Inc. | New | 0.41% | +0.41 |
| DTM DT Midstream Inc. | Add +115.4% | 0.74% | +0.40 |
| NRIX Nurix Therapeutics Inc. | New | 0.38% | +0.38 |
| ARWR Arrowhead Pharmaceuticals Inc. | New | 0.38% | +0.38 |
| TRGP Targa Resources Corp. | Add +27.9% | 1.39% | +0.35 |
| MPWR Monolithic Power Systems Inc. | Add +65.8% | 0.97% | +0.34 |
| NI Nisource Inc. | Add +98.5% | 0.74% | +0.33 |
| CYTK Cytokinetics Inc. | Add +181.9% | 0.48% | +0.32 |
| RNAM Avidity Biosciences Inc. | Add +39.5% | 0.59% | +0.32 |
| INSP Inspire Medical Systems Inc. | Add +71.5% | 0.63% | +0.32 |
| PRAX Praxis Precision Medicines I | New | 0.31% | +0.31 |
| TRVI Trevi Therapeutics Inc. | Add +89.8% | 0.51% | +0.30 |
| TTAN Servicetitan Inc. Class A | Add +1888.6% | 0.30% | +0.28 |
| WEC WEC Energy Group Inc. | Add +550.8% | 0.34% | +0.28 |
| VRT Vertiv Holdings Co. Class A | Add +2884.2% | 0.27% | +0.26 |
| EVMN Evommune Inc. | New | 0.26% | +0.26 |
| RPRX Royalty Pharma PLC Class A | Add +41.5% | 0.78% | +0.25 |
| IVVD Invivyd Inc. | New | 0.22% | +0.22 |
| BKR Baker Hughes Co. | Add +1042.6% | 0.25% | +0.22 |
| OLMA Olema Pharmaceuticals Inc. | New | 0.22% | +0.22 |
| MAZE Maze Therapeutics Inc. | New | 0.21% | +0.21 |
| IMMX Immix Biopharma Inc. | New | 0.21% | +0.21 |
| DYN Dyne Therapeutics Inc. | New | 0.21% | +0.21 |
| CGON CG Oncology Inc. | New | 0.20% | +0.20 |
| GNRC Generac Holdings Inc. | New | 0.20% | +0.20 |
| BE Bloom Energy Corp. Class A | New | 0.19% | +0.19 |
| QURE Uniqure NV | New | 0.19% | +0.19 |
| ADCT Adc Therapeutics SA | New | 0.19% | +0.19 |
| CSTL Castle Biosciences Inc. | New | 0.19% | +0.19 |
| HTFL Heartflow Inc. | Add +502.4% | 0.23% | +0.18 |
| PLD Prologis Inc. | Add +20.2% | 0.84% | +0.18 |
| PVLA Palvella Therapeutics Inc. | New | 0.17% | +0.17 |
| HELP Cybin Inc. | New | 0.16% | +0.16 |
| SNDX Syndax Pharmaceuticals Inc. | Add +25.3% | 0.41% | +0.16 |
| IRON Disc Medicine Inc. | Add +28.4% | 0.49% | +0.16 |
| GRMN Garmin Ltd. | Add +280.0% | 0.22% | +0.15 |
| ENGN Engene Holdings Inc. | New | 0.13% | +0.13 |
| WVE Wave Life Sciences Ltd. | New | 0.13% | +0.13 |
| DRUG Bright Minds Biosciences Inc. | New | 0.13% | +0.13 |
| FIX Comfort Systems USA Inc. | New | 0.12% | +0.12 |
| TER Teradyne Inc. | New | 0.12% | +0.12 |
| PWR Quanta Services Inc. | Add +28.3% | 0.59% | +0.11 |
Notes & Other Activity Q3 2025 → Q4 2025
| CELCUITY INC (CELC 2.75 08/01/31) | NOTE 2.750% 8/0 · principal | Sold out | 500,000 | $666Kbefore exit |
Bonds, preferreds, convertibles and warrants; not part of the stock holdings or percentages above.
All Filings
| Quarter | Positions | 13F Reported Value | Top Holdings |
|---|---|---|---|
| Q2 2026 | 301 | $7.5B | GH, LRCX, XMTR, TT, MIRM |
| Q1 2026 | 278 | $6.0B | GH, TT, LRCX, MIRM, TRGP |
| Q4 2025 | 268 | $6.4B | GH, XMTR, MIRM, TT, BBNX |
| Q3 2025 | 239 | $6.1B | GH, MIRM, XMTR, TT, INSM |
| Q2 2025 | 237 | $5.7B | VRNA, GH, TT, MIRM, INSM |
| Q1 2025 | 217 | $5.0B | VRNA, GH, TT, MIRM, ROP |
| Q4 2024 | 204 | $5.5B | VRNA, TT, XMTR, GH, SRRK |
| Q3 2024 | 180 | $5.8B | TT, DHI, ODFL, ROP, WCN |
| Q2 2024 | 159 | $5.8B | TT, TMDX, WCN, ROP, ODFL |
| Q1 2024 | 156 | $6.4B | TT, ZNTL, SWAV, ODFL, ROP |