Howard Hughes Medical Institute

In its 13F for Q2 2025 (holdings as of June 30, 2025, filed August 14, 2025), Howard Hughes Medical Institute reported 501 stock positions worth $250.9 million. Its top holding was SS SPDR S&P 500 ETF Trust-US (SPY) at 95.5% of the portfolio, followed by Nvidia (NVDA, 0.3%) and Microsoft (MSFT, 0.3%). Compared with Q1 2025, it opened 500 new positions, sold out of 1 and added to 1. The biggest buy was a new position in Nvidia (NVDA) and the biggest sale an exit from Bioage Labs (BIOA).

Most Recent 13F
Q2 2026
Location
Chevy Chase, MD
CIK
0000810386
Portfolio Value
$250.9M (Q2 2025)
SEC Filing
0000950123-25-007937 ↗ filed Aug 14, 2025

Holdings Value

0$200.0M$400.0M$600.0M$800.0M Q1 2024: $332.9M Q1 2024 Q2 2024: $466.2M Q2 2024 Q3 2024: $630.4M Q3 2024 Q4 2024: $568.4M Q4 2024 Q1 2025: $202.2M Q1 2025 Q2 2025: $250.9M $250.9M Q2 2025 Q3 2025: $170.6M Q3 2025 Q4 2025: $174.7M Q4 2025 Q1 2026: $415.8M Q1 2026 Q2 2026: $445.4M Q2 2026

Holdings 501 stocks · $250.9M

SPY SS SPDR S&P 500 ETF Trust-US 95.52% 387,885 $239.7M Add +7.5%
NVDA Nvidia Corp. 0.33% 5,285 $835K New
MSFT Microsoft Corp. 0.32% 1,611 $801K New
AAPL Apple Inc. 0.26% 3,232 $663K New
AMZN Amazon.com Inc. 0.18% 2,039 $447K New
META Meta Platforms Inc. Class A 0.14% 473 $349K New
AVGO Broadcom Inc. 0.11% 1,011 $279K New
GOOGL Alphabet Inc. Class A 0.09% 1,260 $222K New
BRK.B Berkshire Hathaway Inc. Class B 0.08% 396 $192K New
TSLA Tesla Inc. 0.08% 601 $191K New
GOOG Alphabet Inc. Class C 0.07% 1,021 $181K New
JPM JPMorgan Chase & Co. 0.07% 605 $175K New
LLY Eli Lilly & Co. 0.05% 170 $133K New
V Visa Inc. Class A 0.05% 372 $132K New
NFLX Netflix Inc. 0.05% 92 $123K New
XOM Exxon Mobil Corp. 0.04% 943 $102K New
MA Mastercard Inc. Class A 0.04% 176 $99K New
COST Costco Wholesale Corp. 0.04% 95 $94K New
WMT Walmart Inc. 0.04% 937 $92K New
PG The Procter & Gamble Co. 0.03% 506 $81K New
JNJ Johnson & Johnson 0.03% 520 $79K New
HD Home Depot Inc. 0.03% 214 $78K New
ORCL Oracle Corp. 0.03% 350 $77K New
ABBV Abbvie Inc. 0.03% 381 $71K New
BAC Bank of America Corp. filed as BANK AMERICA CORP 0.03% 1,432 $68K New
UNH Unitedhealth Group Inc. 0.02% 198 $62K New
PLTR Palantir Technologies Inc. Class A 0.02% 441 $60K New
CSCO Cisco Systems Inc. 0.02% 860 $60K New
GE General Electric filed as GE AEROSPACE 0.02% 231 $59K New
KO The Coca-Cola Co. 0.02% 836 $59K New
IBM Intl Business Machines Corp. filed as INTERNATIONAL BUSINESS MACHS 0.02% 199 $59K New
WFC Wells Fargo & Co. 0.02% 711 $57K New
CRM Salesforce Inc. 0.02% 206 $56K New
CVX Chevron Corp. 0.02% 361 $52K New
ABT Abbott Laboratories 0.02% 374 $51K New
AMD Advanced Micro Devices 0.02% 350 $50K New
DIS The Walt Disney Co. filed as DISNEY WALT CO 0.02% 390 $48K New
LIN Linde PLC 0.02% 102 $48K New
GS Goldman Sachs Group Inc. 0.02% 67 $47K New
INTU Intuit Inc. 0.02% 60 $47K New
NOW ServiceNow Inc. 0.02% 44 $45K New
T AT&T Inc. 0.02% 1,557 $45K New
MCD McDonald's Corp. 0.02% 154 $45K New
MRK Merck & Co. Inc. 0.02% 546 $43K New
UBER Uber Technologies Inc. 0.02% 451 $42K New
RTX RTX Corp. 0.02% 287 $42K New
ISRG Intuitive Surgical Inc. 0.02% 77 $42K New
TXN Texas Instruments Inc. 0.02% 196 $41K New
BKNG Booking Holdings Inc. 0.02% 7 $41K New
ACN Accenture PLC Class A 0.02% 135 $40K New
CAT Caterpillar Inc. 0.02% 103 $40K New
VZ Verizon Communications Inc. 0.02% 909 $39K New
PEP Pepsico Inc. 0.02% 296 $39K New
QCOM Qualcomm Inc. 0.02% 239 $38K New
AXP American Express Co. 0.02% 119 $38K New
MS Morgan Stanley 0.01% 267 $38K New
ADBE Adobe Inc. 0.01% 94 $36K New
SPGI S&P Global Inc. 0.01% 68 $36K New
C Citigroup Inc. 0.01% 405 $34K New
BSX Boston Scientific Corp. 0.01% 318 $34K New
BA The Boeing Co. 0.01% 162 $34K New
PGR Progressive Corp. 0.01% 126 $34K New
SCHW Schwab (charles) Corp. 0.01% 368 $34K New
TMO Thermo Fisher Scientific Inc. 0.01% 82 $33K New
HON Honeywell International Inc. 0.01% 140 $33K New
BLK BlackRock Inc. 0.01% 31 $33K New
AMGN Amgen Inc. 0.01% 116 $32K New
AMAT Applied Materials Inc. 0.01% 175 $32K New
GEV GE Vernova Inc. 0.01% 59 $31K New
NEE Nextera Energy Inc. 0.01% 444 $31K New
ETN Eaton Corp. PLC 0.01% 85 $30K New
UNP Union Pacific Corp. 0.01% 130 $30K New
TJX TJX Companies Inc. filed as TJX COS INC NEW 0.01% 242 $30K New
GILD Gilead Sciences Inc. 0.01% 269 $30K New
PFE Pfizer Inc. 0.01% 1,222 $30K New
MU Micron Technology Inc. 0.01% 240 $30K New
SYK Stryker Corp. 0.01% 74 $29K New
PANW Palo Alto Networks Inc. 0.01% 143 $29K New
CMCSA Comcast Corp. Class A 0.01% 817 $29K New
COF Capital One Financial Corp. 0.01% 137 $29K New
DE Deere & Co. 0.01% 54 $27K New
DHR Danaher Corp. 0.01% 138 $27K New
LOW Lowe's Cos Inc. 0.01% 122 $27K New
CRWD CrowdStrike Holdings Inc. Class A 0.01% 53 $27K New
LRCX Lam Research Corp. 0.01% 277 $27K New
ADP Automatic Data Processing 0.01% 87 $27K New
APH Amphenol Corp. Class A 0.01% 261 $26K New
ADI Analog Devices Inc. 0.01% 107 $25K New
KLAC KLA Corp. 0.01% 28 $25K New
COP Conocophillips 0.01% 275 $25K New
TMUS T-Mobile US Inc. 0.01% 103 $25K New
VRTX Vertex Pharmaceuticals Inc. 0.01% 55 $24K New
MDT Medtronic PLC 0.01% 277 $24K New
BX Blackstone Inc. 0.01% 158 $24K New
CB Chubb Ltd. 0.01% 80 $23K New
MRSH Marsh & McLennan Cos 0.01% 106 $23K New
ANET Arista Networks Inc. 0.01% 223 $23K New
ICE Intercontinental Exchange Inc. 0.01% 124 $23K New
SBUX Starbucks Corp. 0.01% 245 $22K New
AMT American Tower Corp. 0.01% 100 $22K New

Show all 501 holdings

Portfolio Sells Q1 2025 → Q2 2025

BIOA Bioage Labs Inc. Sold out 0.00% −0.21

Portfolio Buys Q1 2025 → Q2 2025

NVDA Nvidia Corp. New 0.33% +0.33
MSFT Microsoft Corp. New 0.32% +0.32
AAPL Apple Inc. New 0.26% +0.26
AMZN Amazon.com Inc. New 0.18% +0.18
META Meta Platforms Inc. Class A New 0.14% +0.14
AVGO Broadcom Inc. New 0.11% +0.11
GOOGL Alphabet Inc. Class A New 0.09% +0.09
BRK.B Berkshire Hathaway Inc. Class B New 0.08% +0.08
TSLA Tesla Inc. New 0.08% +0.08
GOOG Alphabet Inc. Class C New 0.07% +0.07
JPM JPMorgan Chase & Co. New 0.07% +0.07
LLY Eli Lilly & Co. New 0.05% +0.05
V Visa Inc. Class A New 0.05% +0.05
NFLX Netflix Inc. New 0.05% +0.05
XOM Exxon Mobil Corp. New 0.04% +0.04
MA Mastercard Inc. Class A New 0.04% +0.04
COST Costco Wholesale Corp. New 0.04% +0.04
WMT Walmart Inc. New 0.04% +0.04
PG The Procter & Gamble Co. New 0.03% +0.03
JNJ Johnson & Johnson New 0.03% +0.03
HD Home Depot Inc. New 0.03% +0.03
ORCL Oracle Corp. New 0.03% +0.03
ABBV Abbvie Inc. New 0.03% +0.03
BAC Bank of America Corp. New 0.03% +0.03
UNH Unitedhealth Group Inc. New 0.02% +0.02
PLTR Palantir Technologies Inc. Class A New 0.02% +0.02
CSCO Cisco Systems Inc. New 0.02% +0.02
GE General Electric New 0.02% +0.02
KO The Coca-Cola Co. New 0.02% +0.02
IBM Intl Business Machines Corp. New 0.02% +0.02
WFC Wells Fargo & Co. New 0.02% +0.02
CRM Salesforce Inc. New 0.02% +0.02
CVX Chevron Corp. New 0.02% +0.02
ABT Abbott Laboratories New 0.02% +0.02
AMD Advanced Micro Devices New 0.02% +0.02
DIS The Walt Disney Co. New 0.02% +0.02
LIN Linde PLC New 0.02% +0.02
GS Goldman Sachs Group Inc. New 0.02% +0.02
INTU Intuit Inc. New 0.02% +0.02
T AT&T Inc. New 0.02% +0.02
NOW ServiceNow Inc. New 0.02% +0.02
MCD McDonald's Corp. New 0.02% +0.02
MRK Merck & Co. Inc. New 0.02% +0.02
UBER Uber Technologies Inc. New 0.02% +0.02
ISRG Intuitive Surgical Inc. New 0.02% +0.02
RTX RTX Corp. New 0.02% +0.02
BKNG Booking Holdings Inc. New 0.02% +0.02
TXN Texas Instruments Inc. New 0.02% +0.02
ACN Accenture PLC Class A New 0.02% +0.02
CAT Caterpillar Inc. New 0.02% +0.02

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 30$445.4MNVDA, AAPL, GOOGL, MSFT, TSM
Q1 2026 31$415.8MSPY, NVDA, AAPL, GOOGL, MSFT
Q4 2025 500$174.7MSPY, NVDA, AAPL, MSFT, AMZN
Q3 2025 500$170.6MSPY, NVDA, MSFT, AAPL, AMZN
Q2 2025 501$250.9MSPY, NVDA, MSFT, AAPL, AMZN
Q1 2025 2$202.2MSPY, BIOA
Q4 2024 2$568.4MSPY, BIOA
Q3 2024 2$630.4MSPY, BIOA
Q2 2024 1$466.2MSPY
Q1 2024 2$332.9MSPY, PCT