Howard Hughes Medical Institute

In its 13F for Q1 2026 (holdings as of March 31, 2026, filed May 15, 2026), Howard Hughes Medical Institute reported 31 stock positions worth $415.8 million. Its top holding was SS SPDR S&P 500 ETF Trust-US (SPY) at 13.8% of the portfolio, followed by Nvidia (NVDA, 13.5%) and Apple (AAPL, 12.1%). Compared with Q4 2025, it opened 3 new positions, sold out of 472, added to 27 and reduced 1. The biggest buy was Nvidia (NVDA, shares +6069%) and the biggest sale SS SPDR S&P 500 ETF Trust-US (SPY, shares −63%).

Most Recent 13F
Q2 2026
Location
Chevy Chase, MD
CIK
0000810386
Portfolio Value
$415.8M (Q1 2026)
SEC Filing
0001193125-26-225362 ↗ filed May 15, 2026

Holdings Value

0$200.0M$400.0M$600.0M$800.0M Q1 2024: $332.9M Q1 2024 Q2 2024: $466.2M Q2 2024 Q3 2024: $630.4M Q3 2024 Q4 2024: $568.4M Q4 2024 Q1 2025: $202.2M Q1 2025 Q2 2025: $250.9M Q2 2025 Q3 2025: $170.6M Q3 2025 Q4 2025: $174.7M Q4 2025 Q1 2026: $415.8M $415.8M Q1 2026 Q2 2026: $445.4M Q2 2026

Holdings 31 stocks · $415.8M

SPY SS SPDR S&P 500 ETF Trust-US 13.79% 88,185 $57.4M Reduce -62.9%
NVDA Nvidia Corp. 13.51% 322,105 $56.2M Add +6069.4%
AAPL Apple Inc. 12.13% 198,755 $50.4M Add +6142.3%
GOOGL Alphabet Inc. Class A 9.94% 143,665 $41.3M Add +11393.2%
MSFT Microsoft Corp. 9.11% 102,314 $37.9M Add +6294.6%
AMZN Amazon.com Inc. 6.66% 132,871 $27.7M Add +6248.4%
TSM Taiwan Semiconductor-SP ADR 5.43% 66,773 $22.6M New
AVGO Broadcom Inc. 4.84% 65,028 $20.1M Add +6300.4%
META Meta Platforms Inc. Class A 4.24% 30,787 $17.6M Add +6464.4%
TSLA Tesla Inc. 3.68% 41,177 $15.3M Add +6728.7%
ASML ASML Holding NV-NY Reg SHS filed as ASML HLDG NV 1.72% 5,405 $7.1M New
NFLX Netflix Inc. 1.36% 58,670 $5.6M Add +6326.1%
MU Micron Technology Inc. 1.28% 15,704 $5.3M Add +6416.2%
AMD Advanced Micro Devices 1.11% 22,624 $4.6M Add +6364.0%
PLTR Palantir Technologies Inc. Class A 1.08% 30,757 $4.5M Add +6176.9%
CSCO Cisco Systems Inc. 0.94% 50,326 $3.9M Add +5820.7%
AMAT Applied Materials Inc. 0.90% 10,984 $3.8M Add +6286.1%
LRCX Lam Research Corp. 0.89% 17,396 $3.7M Add +6343.0%
ORCL Oracle Corp. 0.84% 23,851 $3.5M Add +6525.3%
IBM Intl Business Machines Corp. filed as INTERNATIONAL BUSINESS MACHS 0.76% 13,023 $3.2M Add +6379.1%
KLAC KLA Corp. 0.65% 1,825 $2.7M Add +6417.9%
SAP Sap SE-Sponsored ADR 0.61% 14,868 $2.5M New
INTC Intel Corp. 0.61% 57,142 $2.5M Add +5821.4%
TXN Texas Instruments Inc. 0.59% 12,645 $2.5M Add +6351.5%
DIS The Walt Disney Co. filed as DISNEY WALT CO 0.57% 24,660 $2.4M Add +6305.2%
CRM Salesforce Inc. 0.57% 12,612 $2.4M Add +6052.2%
UBER Uber Technologies Inc. 0.50% 28,895 $2.1M Add +6364.2%
QCOM Qualcomm Inc. 0.46% 14,838 $1.9M Add +6295.7%
BKNG Booking Holdings Inc. 0.45% 444 $1.9M Add +6242.9%
ACN Accenture PLC Class A 0.41% 8,607 $1.7M Add +6323.1%
INTU Intuit Inc. 0.39% 3,794 $1.6M Add +6223.3%

Portfolio Sells Q4 2025 → Q1 2026

SPY SS SPDR S&P 500 ETF Trust-US Reduce -62.9% 13.79% −79.06
GOOG Alphabet Inc. Class C Sold out 0.00% −0.18
BRK.B Berkshire Hathaway Inc. Class B Sold out 0.00% −0.11
JPM JPMorgan Chase & Co. Sold out 0.00% −0.11
LLY Eli Lilly & Co. Sold out 0.00% −0.11
V Visa Inc. Class A Sold out 0.00% −0.07
XOM Exxon Mobil Corp. Sold out 0.00% −0.06
JNJ Johnson & Johnson Sold out 0.00% −0.06
WMT Walmart Inc. Sold out 0.00% −0.06
MA Mastercard Inc. Class A Sold out 0.00% −0.06
ABBV Abbvie Inc. Sold out 0.00% −0.05
COST Costco Wholesale Corp. Sold out 0.00% −0.05
BAC Bank of America Corp. Sold out 0.00% −0.05
HD Home Depot Inc. Sold out 0.00% −0.04
PG The Procter & Gamble Co. Sold out 0.00% −0.04
GE General Electric Sold out 0.00% −0.04
UNH Unitedhealth Group Inc. Sold out 0.00% −0.04
WFC Wells Fargo & Co. Sold out 0.00% −0.04
CVX Chevron Corp. Sold out 0.00% −0.04
KO The Coca-Cola Co. Sold out 0.00% −0.03
CAT Caterpillar Inc. Sold out 0.00% −0.03
GS Goldman Sachs Group Inc. Sold out 0.00% −0.03
MRK Merck & Co. Inc. Sold out 0.00% −0.03
RTX RTX Corp. Sold out 0.00% −0.03
ABT Abbott Laboratories Sold out 0.00% −0.03
MCD McDonald's Corp. Sold out 0.00% −0.03
TMO Thermo Fisher Scientific Inc. Sold out 0.00% −0.03
MS Morgan Stanley Sold out 0.00% −0.03
C Citigroup Inc. Sold out 0.00% −0.03
ISRG Intuitive Surgical Inc. Sold out 0.00% −0.03
AXP American Express Co. Sold out 0.00% −0.02
LIN Linde PLC Sold out 0.00% −0.02
PEP Pepsico Inc. Sold out 0.00% −0.02
APP AppLovin Corp. Class A Sold out 0.00% −0.02
GEV GE Vernova Inc. Sold out 0.00% −0.02
T AT&T Inc. Sold out 0.00% −0.02
AMGN Amgen Inc. Sold out 0.00% −0.02
VZ Verizon Communications Inc. Sold out 0.00% −0.02
TJX TJX Companies Inc. Sold out 0.00% −0.02
BA The Boeing Co. Sold out 0.00% −0.02
NEE Nextera Energy Inc. Sold out 0.00% −0.02
SCHW Schwab (charles) Corp. Sold out 0.00% −0.02
APH Amphenol Corp. Class A Sold out 0.00% −0.02
SPGI S&P Global Inc. Sold out 0.00% −0.02
NOW ServiceNow Inc. Sold out 0.00% −0.02
BLK BlackRock Inc. Sold out 0.00% −0.02
COF Capital One Financial Corp. Sold out 0.00% −0.02
GILD Gilead Sciences Inc. Sold out 0.00% −0.02
ADBE Adobe Inc. Sold out 0.00% −0.02
DHR Danaher Corp. Sold out 0.00% −0.02

Portfolio Buys Q4 2025 → Q1 2026

NVDA Nvidia Corp. Add +6069.4% 13.51% +12.95
AAPL Apple Inc. Add +6142.3% 12.13% +11.64
GOOGL Alphabet Inc. Class A Add +11393.2% 9.94% +9.71
MSFT Microsoft Corp. Add +6294.6% 9.11% +8.67
AMZN Amazon.com Inc. Add +6248.4% 6.66% +6.38
TSM Taiwan Semiconductor-SP ADR New 5.43% +5.43
AVGO Broadcom Inc. Add +6300.4% 4.84% +4.64
META Meta Platforms Inc. Class A Add +6464.4% 4.24% +4.06
TSLA Tesla Inc. Add +6728.7% 3.68% +3.53
ASML ASML Holding NV-NY Reg SHS New 1.72% +1.72
NFLX Netflix Inc. Add +6326.1% 1.36% +1.31
MU Micron Technology Inc. Add +6416.2% 1.28% +1.24
AMD Advanced Micro Devices Add +6364.0% 1.11% +1.06
PLTR Palantir Technologies Inc. Class A Add +6176.9% 1.08% +1.03
CSCO Cisco Systems Inc. Add +5820.7% 0.94% +0.90
AMAT Applied Materials Inc. Add +6286.1% 0.90% +0.88
LRCX Lam Research Corp. Add +6343.0% 0.89% +0.87
ORCL Oracle Corp. Add +6525.3% 0.84% +0.80
IBM Intl Business Machines Corp. Add +6379.1% 0.76% +0.73
KLAC KLA Corp. Add +6417.9% 0.65% +0.63
SAP Sap SE-Sponsored ADR New 0.61% +0.61
INTC Intel Corp. Add +5821.4% 0.61% +0.59
TXN Texas Instruments Inc. Add +6351.5% 0.59% +0.57
DIS The Walt Disney Co. Add +6305.2% 0.57% +0.55
CRM Salesforce Inc. Add +6052.2% 0.57% +0.54
UBER Uber Technologies Inc. Add +6364.2% 0.50% +0.48
QCOM Qualcomm Inc. Add +6295.7% 0.46% +0.44
BKNG Booking Holdings Inc. Add +6242.9% 0.45% +0.43
ACN Accenture PLC Class A Add +6323.1% 0.41% +0.39
INTU Intuit Inc. Add +6223.3% 0.39% +0.37

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 30$445.4MNVDA, AAPL, GOOGL, MSFT, TSM
Q1 2026 31$415.8MSPY, NVDA, AAPL, GOOGL, MSFT
Q4 2025 500$174.7MSPY, NVDA, AAPL, MSFT, AMZN
Q3 2025 500$170.6MSPY, NVDA, MSFT, AAPL, AMZN
Q2 2025 501$250.9MSPY, NVDA, MSFT, AAPL, AMZN
Q1 2025 2$202.2MSPY, BIOA
Q4 2024 2$568.4MSPY, BIOA
Q3 2024 2$630.4MSPY, BIOA
Q2 2024 1$466.2MSPY
Q1 2024 2$332.9MSPY, PCT