Omega Fund Management, LLC

In its 13F for Q2 2026 (holdings as of June 30, 2026, filed August 14, 2026), Omega Fund Management, LLC reported 10 stock positions worth $185.7 million. Its top holding was Bicara Therapeutics (BCAX) at 29.1% of the portfolio, followed by Nuvation Bio (NUVB, 24.7%) and Kestra Medical Technologies (KMTS, 14.0%). Compared with Q1 2026, it opened 1 new position, sold out of 1 and reduced 1. The biggest buy was a new position in Odyssey Therapeutics (ODTX) and the biggest sale an exit from Replimune (REPL).

Most Recent 13F
Q2 2026
Location
Boston, MA
CIK
0001637359
Portfolio Value
$185.7M (Q2 2026)
SEC Filing
0001193125-26-350681 ↗ filed Aug 14, 2026

Holdings Value

0$100.0M$200.0M$300.0M Q1 2024: $155.0M Q1 2024 Q2 2024: $135.0M Q2 2024 Q3 2024: $160.0M Q3 2024 Q4 2024: $154.2M Q4 2024 Q1 2025: $169.5M Q1 2025 Q2 2025: $154.4M Q2 2025 Q3 2025: $222.4M Q3 2025 Q4 2025: $286.5M Q4 2025 Q1 2026: $163.1M Q1 2026 Q2 2026: $185.7M $185.7M Q2 2026

Holdings 10 stocks · $185.7M

BCAX Bicara Therapeutics Inc. 29.14% 1,822,150 $54.1M Reduce -23.8%
NUVB Nuvation Bio Inc. 24.72% 8,081,089 $45.9M No change
KMTS Kestra Medical Technologies 14.00% 1,022,149 $26.0M No change
BBOT Bridgebio Oncology Therapeut 13.50% 3,289,661 $25.1M No change
BBNX Beta Bionics Inc. 11.11% 1,316,183 $20.6M No change
ALMS Alumis Inc. 3.66% 241,255 $6.8M No change
SANA Sana Biotechnology Inc. 1.59% 843,750 $2.9M No change
IMA Imagenebio Inc. 1.45% 455,361 $2.7M No change
ENGN Engene Holdings Inc. 0.82% 876,357 $1.5M No change
ODTX Odyssey Therapeutics Inc. 0.03% 2,893 $54K New

Portfolio Sells Q1 2026 → Q2 2026

REPL Replimune Group Inc. Sold out 0.00% −1.17
BCAX Bicara Therapeutics Inc. Reduce -23.8% 29.14% −0.03

Portfolio Buys Q1 2026 → Q2 2026

ODTX Odyssey Therapeutics Inc. New 0.03% +0.03

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 10$185.7MBCAX, NUVB, KMTS, BBOT, BBNX
Q1 2026 10$163.1MBCAX, NUVB, BBOT, KMTS, BBNX
Q4 2025 11$286.5MNUVB, BBOT, BBNX, BCAX, KMTS
Q3 2025 12$222.4MKMTS, BBNX, BBOT, BCAX, NUVB
Q2 2025 13$154.4MBBNX, KMTS, UPB, NUVB, BCAX
Q1 2025 13$169.5MKMTS, BCAX, BBNX, NUVB, REPL
Q4 2024Amended 12$154.2MBCAX, NUVB, UPB, REPL, LXEO
Q3 2024 11$160.0MBCAX, NUVB, REPL, LXEO, ENGN
Q2 2024 11$135.0MNUVB, LXEO, REPL, ENGN, ALMS
Q1 2024 11$155.0MNUVB, LXEO, REPL, ENGN, SANA